CoChat
Sign Up
Cited by 246

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Novel roles for A-type lamins in telomere biology and the DNA damage response pathway

Gonzalez‐Suarez, Ignacio, Redwood, Abena B, Perkins, Stephanie M, Vermolen, Bart, Lichtensztejin, Daniel, Grotsky, David A, Morgado‐Palacin, Lucia, Gapud, Eric J, Sleckman, Barry P, Sullivan, Teresa, Sage, Julien, Stewart, Colin L, Mai, Sabine, Gonzalo, Susana·2009·The EMBO Journal
DOI 10.1038/emboj.2009.196
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1038/emboj.2009.196

Cites

11 of 11 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Show all 11 references

Research works printed but not linked: 59

  1. Agrelo R, Setien F, Espada J, Artiga MJ, Rodriguez M, Perez‐Rosado A, Sanchez‐Aguilera A, Fraga MF, Piris MA, Esteller M (2005) Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B‐cell lymphoma. J Clin Oncol 23: 3940–3947 · DOI
  2. Akhtar A, Gasser SM (2007) The nuclear envelope and transcriptional control. Nat Rev Genet 8: 507–517 · DOI
  3. Allsopp RC, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB, Greider CW, Harley CB (1992) Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 89: 10114–10118 · DOI · Paper page
  4. Azzalin CM, Reichenbach P, Khoriauli L, Giulotto E, Lingner J (2007) Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science 318: 798–801 · DOI
  5. Bailey SM, Brenneman MA, Goodwin EH (2004) Frequent recombination in telomeric DNA may extend the proliferative life of telomerase‐negative cells. Nucleic Acids Res 32: 3743–3751 · DOI
  6. Bailey SM, Cornforth MN, Kurimasa A, Chen DJ, Goodwin EH (2001) Strand‐specific postreplicative processing of mammalian telomeres. Science 293: 2462–2465 · DOI
  7. Benetti R, Gonzalo S, Jaco I, Schotta G, Klatt P, Jenuwein T, Blasco MA (2007) Suv4‐20h deficiency results in telomere elongation and derepression of telomere recombination. J Cell Biol 178: 925–936 · DOI
  8. Blackburn EH (2001) Switching and signaling at the telomere. Cell 106: 661–673 · DOI
  9. Blackburn EH, Greider CW, Szostak JW (2006) Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging. Nat Med 12: 1133–1138 · DOI · Paper page
  10. Blasco MA (2007) The epigenetic regulation of mammalian telomeres. Nat Rev Genet 8: 299–309 · DOI · Paper page
  11. Broers JL, Ramaekers FC, Bonne G, Yaou RB, Hutchison CJ (2006) Nuclear lamins: laminopathies and their role in premature ageing. Physiol Rev 86: 967–1008 · DOI
  12. Broers JL, Raymond Y, Rot MK, Kuijpers H, Wagenaar SS, Ramaekers FC (1993) Nuclear A‐type lamins are differentially expressed in human lung cancer subtypes. Am J Pathol 143: 211–220
  13. Capell BC, Collins FS (2006) Human laminopathies: nuclei gone genetically awry. Nat Rev Genet 7: 940–952 · DOI
  14. Chuang TC, Moshir S, Garini Y, Chuang AY, Young IT, Vermolen B, van den Doel R, Mougey V, Perrin M, Braun M, Kerr PD, Fest T, Boukamp P, Mai S (2004) The three‐dimensional organization of telomeres in the nucleus of mammalian cells. BMC Biol 2: 12 · DOI
  15. De Lange T (2005b) Telomere‐related genome instability in cancer. Cold Spring Harb Symp Quant Biol 70: 197–204 · DOI · Paper page
  16. Dechat T, Pfleghaar K, Sengupta K, Shimi T, Shumaker DK, Solimando L, Goldman RD (2008) Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin. Genes Dev 22: 832–853 · DOI · Paper page
  17. di Masi A, D'Apice MR, Ricordy R, Tanzarella C, Novelli G (2008) The R527H mutation in LMNA gene causes an increased sensitivity to ionizing radiation. Cell Cycle 7: 2030–2037 · DOI
  18. Dimitrova N, Chen YC, Spector DL, de Lange T (2008) 53BP1 promotes non‐homologous end joining of telomeres by increasing chromatin mobility. Nature 456: 524–528 · DOI
  19. Garcia‐Cao M, O'Sullivan R, Peters AH, Jenuwein T, Blasco MA (2004) Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. Nat Genet 36: 94–99 · DOI
  20. Glass CA, Glass JR, Taniura H, Hasel KW, Blevitt JM, Gerace L (1993) The alpha‐helical rod domain of human lamins A and C contains a chromatin binding site. EMBO J 12: 4413–4424 · DOI
  21. Goldman RD, Gruenbaum Y, Moir RD, Shumaker DK, Spann TP (2002) Nuclear lamins: building blocks of nuclear architecture. Genes Dev 16: 533–547 · DOI
  22. Gonzalo S, Jaco I, Fraga MF, Chen T, Li E, Esteller M, Blasco MA (2006) DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat Cell Biol 8: 416–424 · DOI · Paper page
  23. Gruenbaum Y, Margalit A, Goldman RD, Shumaker DK, Wilson KL (2005) The nuclear lamina comes of age. Nat Rev Mol Cell Biol 6: 21–31 · DOI
  24. Han X, Feng X, Rattner JB, Smith H, Bose P, Suzuki K, Soliman MA, Scott MS, Burke BE, Riabowol K (2008) Tethering by lamin A stabilizes and targets the ING1 tumour suppressor. Nat Cell Biol 10: 1333–1340 · DOI
  25. Herrera E, Samper E, Blasco MA (1999) Telomere shortening in mTR−/− embryos is associated with failure to close the neural tube. EMBO J 18: 1172–1181 · DOI · Paper page
  26. Huang S, Risques RA, Martin GM, Rabinovitch PS, Oshima J (2008) Accelerated telomere shortening and replicative senescence in human fibroblasts overexpressing mutant and wild‐type lamin A. Exp Cell Res 314: 82–91 · DOI
  27. Johnson BR, Nitta RT, Frock RL, Mounkes L, Barbie DA, Stewart CL, Harlow E, Kennedy BK (2004) A‐type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation. Proc Natl Acad Sci USA 101: 9677–9682 · DOI
  28. Kudlow BA, Stanfel MN, Burtner CR, Johnston ED, Kennedy BK (2008) Suppression of proliferative defects associated with processing‐defective lamin A mutants by hTERT or inactivation of p53. Mol Biol Cell 19: 5238–5248 · DOI
  29. Kumaran RI, Muralikrishna B, Parnaik VK (2002) Lamin A/C speckles mediate spatial organization of splicing factor compartments and RNA polymerase II transcription. J Cell Biol 159: 783–793 · DOI
  30. Liu D, O'Connor MS, Qin J, Songyang Z (2004) Telosome, a mammalian telomere‐associated complex formed by multiple telomeric proteins. J Biol Chem 279: 51338–51342 · DOI · Paper page
  31. Luke B, Panza A, Redon S, Iglesias N, Li Z, Lingner J (2008) The Rat1p 5′ to 3′ exonuclease degrades telomeric repeat‐containing RNA and promotes telomere elongation in Saccharomyces cerevisiae. Mol Cell 32: 465–477 · DOI
  32. Mai S, Garini Y (2006) The significance of telomeric aggregates in the interphase nuclei of tumor cells. J Cell Biochem 97: 904–915 · DOI
  33. Mekhail K, Seebacher J, Gygi SP, Moazed D (2008) Role for perinuclear chromosome tethering in maintenance of genome stability. Nature 456: 667–670 · DOI
  34. Misteli T (2007) Beyond the sequence: cellular organization of genome function. Cell 128: 787–800 · DOI
  35. Mounkes LC, Stewart CL (2004) Aging and nuclear organization: lamins and progeria. Curr Opin Cell Biol 16: 322–327 · DOI
  36. Munoz P, Blanco R, Flores JM, Blasco MA (2005) XPF nuclease‐dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer. Nat Genet 37: 1063–1071 · DOI
  37. Nagai S, Dubrana K, Tsai‐Pflugfelder M, Davidson MB, Roberts TM, Brown GW, Varela E, Hediger F, Gasser SM, Krogan NJ (2008) Functional targeting of DNA damage to a nuclear pore‐associated SUMO‐dependent ubiquitin ligase. Science 322: 597–602 · DOI
  38. Ng LJ, Cropley JE, Pickett HA, Reddel RR, Suter CM (2009) Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription. Nucleic Acids Res 37: 1152–1159 · DOI
  39. Nitta RT, Jameson SA, Kudlow BA, Conlan LA, Kennedy BK (2006) Stabilization of the retinoblastoma protein by A‐type nuclear lamins is required for INK4A‐mediated cell cycle arrest. Mol Cell Biol 26: 5360–5372 · DOI
  40. Prokocimer M, Davidovich M, Nissim‐Rafinia M, Wiesel‐Motiuk N, Bar D, Barkan R, Meshorer E, Gruenbaum Y (2009) Nuclear lamins: key regulators of nuclear structure and activities. J Cell Mol Med 13: 1059–1085 · DOI
  41. Prokocimer M, Margalit A, Gruenbaum Y (2006) The nuclear lamina and its proposed roles in tumorigenesis: projection on the hematologic malignancies and future targeted therapy. J Struct Biol 155: 351–360 · DOI
  42. Raz V, Vermolen BJ, Garini Y, Onderwater JJ, Mommaas‐Kienhuis MA, Koster AJ, Young IT, Tanke H, Dirks RW (2008) The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells. J Cell Sci 121: 4018–4028 · DOI
  43. Riha K, Heacock ML, Shippen DE (2006) The role of the nonhomologous end‐joining DNA double‐strand break repair pathway in telomere biology. Annu Rev Genet 40: 237–277 · DOI
  44. Scaffidi P, Misteli T (2006) Lamin A‐dependent nuclear defects in human aging. Science 312: 1059–1063 · DOI · Paper page
  45. Schermelleh L, Carlton PM, Haase S, Shao L, Winoto L, Kner P, Burke B, Cardoso MC, Agard DA, Gustafsson MG, Leonhardt H, Sedat JW (2008) Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy. Science 320: 1332–1336 · DOI
  46. Schoeftner S, Blasco MA (2008) Developmentally regulated transcription of mammalian telomeres by DNA‐dependent RNA polymerase II. Nat Cell Biol 10: 228–236 · DOI
  47. Shechter D, Dormann HL, Allis CD, Hake SB (2007) Extraction, purification and analysis of histones. Nat Protoc 2: 1445–1457 · DOI
  48. Shumaker DK, Dechat T, Kohlmaier A, Adam SA, Bozovsky MR, Erdos MR, Eriksson M, Goldman AE, Khuon S, Collins FS, Jenuwein T, Goldman RD (2006) Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging. Proc Natl Acad Sci USA 103: 8703–8708 · DOI · Paper page
  49. Smogorzewska A, Karlseder J, Holtgreve‐Grez H, Jauch A, de Lange T (2002) DNA ligase IV‐dependent NHEJ of deprotected mammalian telomeres in G1 and G2. Curr Biol 12: 1635–1644 · DOI
  50. Spann TP, Goldman AE, Wang C, Huang S, Goldman RD (2002) Alteration of nuclear lamin organization inhibits RNA polymerase II‐dependent transcription. J Cell Biol 156: 603–608 · DOI
  51. Stewart CL, Kozlov S, Fong LG, Young SG (2007) Mouse models of the laminopathies. Exp Cell Res 313: 2144–2156 · DOI
  52. Stierle V, Couprie J, Ostlund C, Krimm I, Zinn‐Justin S, Hossenlopp P, Worman HJ, Courvalin JC, Duband‐Goulet I (2003) The carboxyl‐terminal region common to lamins A and C contains a DNA binding domain. Biochemistry 42: 4819–4828 · DOI
  53. Sullivan T, Escalante‐Alcalde D, Bhatt H, Anver M, Bhat N, Nagashima K, Stewart CL, Burke B (1999) Loss of A‐type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy. J Cell Biol 147: 913–920 · DOI
  54. Taddei A, Hediger F, Neumann FR, Gasser SM (2004) The function of nuclear architecture: a genetic approach. Annu Rev Genet 38: 305–345 · DOI
  55. Takai H, Smogorzewska A, de Lange T (2003) DNA damage foci at dysfunctional telomeres. Curr Biol 13: 1549–1556 · DOI · Paper page
  56. Therizols P, Fairhead C, Cabal GG, Genovesio A, Olivo‐Marin JC, Dujon B, Fabre E (2006) Telomere tethering at the nuclear periphery is essential for efficient DNA double strand break repair in subtelomeric region. J Cell Biol 172: 189–199 · DOI
  57. Vermolen BJ, Garini Y, Mai S, Mougey V, Fest T, Chuang TC, Chuang AY, Wark L, Young IT (2005) Characterizing the three‐dimensional organization of telomeres. Cytometry A 67: 144–150 · DOI
  58. Willis ND, Cox TR, Rahman‐Casans SF, Smits K, Przyborski SA, van den Brandt P, van Engeland M, Weijenberg M, Wilson RG, de Bruine A, Hutchison CJ (2008) Lamin A/C is a risk biomarker in colorectal cancer. PLoS ONE 3: e2988 · DOI
  59. Zijlmans JM, Martens UM, Poon SS, Raap AK, Tanke HJ, Ward RK, Lansdorp PM (1997) Telomeres in the mouse have large inter‐chromosomal variations in the number of T2AG3 repeats. Proc Natl Acad Sci USA 94: 7423–7428 · DOI

Cited by

Sorted by citations

See all 246

Metadata

Authors
Gonzalez‐Suarez, I., Redwood, A. B., Perkins, S. M., Vermolen, B., Lichtensztejin, D., Grotsky, D. A., Morgado‐Palacin, L., Gapud, E. J., Sleckman, B. P., Sullivan, T., Sage, J., Stewart, C. L., Mai, S., & Gonzalo, S.
Venue
The EMBO Journal
Publisher
Springer Science and Business Media LLC
Published
2009-07-23
Volume
28
Issue
16
Pages
2414-2427
ISSN
  • 0261-4189
  • 1460-2075
DOI
10.1038/emboj.2009.196
Cited by
246
References
11
Language
en
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review