The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Osteochondral tissue engineering: scaffolds, stem cells and applications
Open accessAbstract
Osteochondral tissue engineering has shown an increasing development to provide suitable strategies for the regeneration of damaged cartilage and underlying subchondral bone tissue. For reasons of the limitation in the capacity of articular cartilage to self‐repair, it is essential to develop approaches based on suitable scaffolds made of appropriate engineered biomaterials. The combination of biodegradable polymers and bioactive ceramics in a variety of composite structures is promising in this area, whereby the fabrication methods, associated cells and signalling factors determine the success of the strategies. The objective of this review is to present and discuss approaches being proposed in osteochondral tissue engineering, which are focused on the application of various materials forming bilayered composite scaffolds, including polymers and ceramics, discussing the variety of scaffold designs and fabrication methods being developed. Additionally, cell sources and biological protein incorporation methods are discussed, addressing their interaction with scaffolds and highlighting the potential for creating a new generation of bilayered composite scaffolds that can mimic the native interfacial tissue properties, and are able to adapt to the biological environment.
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Petrenko, Y. A., Ivanov, R. V., Petrenko, A. Y., & Lozinsky, V. I. (2011) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-011-4323-6 · Cited by 78 · cited 1×
“[29] investigated Ca-alginate scaffolds with covalently attached gelatin to improve cell adhesion and proliferation.”
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Mohd Roslan, M. R., Mohd Kamal, N. L., Abdul Khalid, M. F., Mohd Nasir, N. F., Cheng, E. M., Beh, C. Y., Tan, J. S., & Mohamed, M. S. (2021) · Materials · doi:10.3390/ma14081960 · Cited by 55
Farkas, B., Romano, I., Ceseracciu, L., Diaspro, A., Brandi, F., & Beke, S. (2015) · Materials Science and Engineering: C · doi:10.1016/j.msec.2015.05.054 · Cited by 24
Metadata
- Authors
- Nooeaid, P., Salih, V., Beier, J. P., & Boccaccini, A. R.
- Venue
- Journal of Cellular and Molecular Medicine
- Publisher
- Wiley
- Published
- 2012-09-26
- Volume
- 16
- Issue
- 10
- Pages
- 2247-2270
- ISSN
- 1582-1838 (ISSN-L)
- 1582-4934
- OpenAlex
- W2042065329
- Cited by
- 300
- References
- 1
- FWCI
- 12.38
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.