Subthreshold depression and cognitive impairment but not demented in stroke patients during their rehabilitation
Open accessAbstract
BACKGROUND: Subthreshold depression (sD) and cognitive impairment but not demented (CIND) in stroke patients are associated with poorer rehabilitative outcomes. Their diagnosis can easily be operationalized using validated scales. AIM: The aim of the study was to ascertain the prevalence of depressive symptoms and cognitive impairment in stroke patients during three crucial stages of the rehabilitative process, viz. upon admission, upon planned discharges from rehabilitation hospitals and at 6 months post-stroke, using validated scales like the Geriatric Depression Scale and Abbreviated Mental Test (recommended by the British Geriatric Society). Their baseline risk factors were also ascertained. RESULTS: On admission, the prevalence of depressive symptoms and cognitive impairment was 60% and 54% respectively. The prevalence upon planned discharges and 6 months post-stroke, respectively, of depressive symptoms was 38% and 34% and that of impaired cognition was 33% and 40%. Baseline independent correlates at 6 months post-stroke depressive symptoms were: recurrent stroke (OR 3.34); on admission cognitive impairment (OR 4.78) and ADL dependence (OR 5.28). And that of cognitive impairment were: increasing age (OR 8.07); post-stroke dysphagia (OR 4.58); on admission cognitive impairment (OR 23.95) and on admission depressive symptoms (OR 3.50). CONCLUSIONS: Continuous screening and appropriate intervention, especially at baseline, would significantly decrease the burden posed by stroke patients with such psychological impairments in the community.
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Post-stroke depression is the most common neuropsychiatric complication following stroke and affects 20-65% of stroke patients within three to six months.
“Post-stroke depression (PSD) is recognized as the most common neuropsychiatric complication following stroke. Its symptoms develop within three to six months after a stroke event and affect 20–65% of stroke patients.3”
From Effects of Immersive Virtual Therapy as a Method Supporting Recovery of Depressive Symptoms in Post-Stroke Rehabilitation: Randomized Controlled Trial (2022) · cites this paper as [3]
The Introduction (page unavailable) states that major and minor depression occur in 20–65% of stroke patients. The paper reports depressive symptoms at six months after stroke, but does not say symptoms develop within three to six months or identify depression as the most common neuropsychiatric complication. (LLM, conf=0.88)
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- Authors
- Saxena, S. K., Ng, T. P., Yong, D., Fong, N. P., & Koh, G.
- Affiliations
- National University Hospital (SG)
- Changi General Hospital (SG)
- St Luke's Hospital (SG)
- National University of Singapore (SG)
- Corresponding author
- Saxena, S. K.
- Ng, T. P.
- Venue
- Acta Neurologica Scandinavica
- Publisher
- Hindawi Limited
- Published
- 2007-09-04
- Volume
- 0
- Issue
- 0
- Pages
- 070907072758002-???
- ISSN
- 0001-6314 (ISSN-L)
- 1600-0404
- OpenAlex
- W2119180454
- Cited by
- 48
- References
- 52
- Citations by year
- 2025: 1 · 2024: 3 · 2023: 3 · 2022: 3 · 2021: 2 · 2020: 1 · 2019: 3 · 2018: 2 · 2017: 1 · 2016: 2 · 2014: 4 · 2013: 6 · 2012: 3
- FWCI
- 3.25
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Acta Neurologica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- National University of Singapore (submittedVersion)
- Funders
- National University of Singapore
- Topics
- Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Health Professions › Speech and Hearing › Dysphagia Assessment and Management
- Keywords
- subthreshold depression, cognitive impairment, stroke, stroke rehabilitation, depressive symptoms, prevalence, risk factors, stroke recurrence, activities of daily living dependence, post-stroke dysphagia, Geriatric Depression Scale, Abbreviated Mental Test, cognitive screening
- MeSH terms
- Stroke Rehabilitation, Adult, Aged, Aged, 80 and over, Cognition Disorders, Depression, Female, Follow-Up Studies, Humans, Male, Middle Aged, Retrospective Studies, Risk Factors, Time Factors, Stroke
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