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Cited by 199Oral microbiology and periodontitis researchAntioxidant Activity and Oxidative StressDental Health and Care Utilization

The DOI matches its Crossref record; 177 of the 179 references it cites were found in a registry or an index.

Micronutritional approaches to periodontal therapy

Van der Velden, U., Kuzmanova, D., Chapple, I. L. C.·2011·Journal of Clinical Periodontology
DOI 10.1111/j.1600-051x.2010.01663.x
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Abstract

Van der Velden U, Kuzmanova D, Chapple ILC. Micronutritional approaches to periodontal therapy. J Clin Periodontol 2011; 38 (Suppl. 11): 142–158. doi: 10.1111/j.1600‐051X.2010.01663.x. Aim: Periodontitis results from the loss of a delicate balance between microbial virulence factors and a proportionate host response. Nutritional factors have been implicated in several chronic inflammatory diseases that are associated with periodontitis. This manuscript reviews the evidence for nutritional exposures in the etiology and therapeutic management of periodontitis, and makes recommendations for daily nutritional intake for vitamin C (ascorbic acid), vitamin D, calcium, and antioxidants. Results and conclusion: Periodontitis is associated with low serum/plasma micronutrient levels, which may result from dietary and/or life‐style factors as well as nutrigenetic characteristics. Early evidence suggests beneficial outcomes from nutritional interventions; supporting the contention that daily intake of certain nutrients should be at the higher end of recommended daily allowances. For prevention and treatment of periodontitis daily nutrition should include sufficient antioxidants, vitamin D, and calcium. Inadequate antioxidant levels may be managed by higher intake of vegetables, berries, and fruits (e.g. kiwi fruit), or by phytonutrient supplementation. Current evidence is insufficient to support recommendations of mono‐antioxidant vitamin supplements and randomised controlled double‐blind intervention studies are needed to provide evidence to underpin future recommendations. Inadequate supply of vitamin D and calcium may be addressed by implementing changes in diet/life style or by supplements.

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Crossref · 10.1111/j.1600-051x.2010.01663.x

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Research works printed but not linked: 5

  1. Anderson R., 1979, Effects of ascorbate on leucocytes, South African Medical Journal, 56, 429
  2. Food and Nutrition Board., 1997, Diatery Reference Intakes (DRI) for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Food and Nutrition Board (FNB), Institute of Medicine
  3. FNB, 2000, Food and Nutrition Board and panel on dietary antioxidants and related compounds, Vitamin C, 5, 95
  4. Havel R. J., 1989, Recommended Dietary Allowances, Food and Nutrition Board
  5. World Health Organization, 2005, Global Oral Health Data Bank: Periodontal Country Profiles

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Metadata

Authors
Van der Velden, U., Kuzmanova, D., & Chapple, I. L. C.
Affiliations
  • Academic Center for Dentistry Amsterdam (NL)
  • University of Birmingham (GB)
ORCID
Chapple, I. L. C.
Venue
Journal of Clinical Periodontology
Publisher
Wiley
Published
2011-02-16
Volume
38
Issue
s11
Pages
142-158
ISSN
  • 0303-6979 (ISSN-L)
  • 1600-051X
DOI
10.1111/j.1600-051x.2010.01663.x
OpenAlex
W2159104664
Cited by
199
References
179
Citations by year
2026: 6 · 2025: 16 · 2024: 7 · 2023: 13 · 2022: 18 · 2021: 21 · 2020: 14 · 2019: 14 · 2018: 13 · 2017: 13 · 2016: 18 · 2015: 7 · 2014: 15 · 2013: 11 · 2012: 5
FWCI
1.99
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Journal Of Clinical Periodontology (publishedVersion)
  • PubMed (publishedVersion)
  • UvA-DARE (University of Amsterdam) (publishedVersion)
  • VU Research Portal (publishedVersion)
  • UvA-DARE (University of Amsterdam) (submittedVersion)
  • University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
Topics
  • Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
  • Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
  • Health Sciences › Dentistry › General Dentistry › Dental Health and Care Utilization
Keywords
periodontitis, micronutrient nutrition, vitamin C, vitamin D, calcium, antioxidants, phytochemicals, dietary supplementation, nutrigenetics, chronic inflammation, dietary recommendations
MeSH terms
Antioxidants, Ascorbic Acid, Calcium, Dietary, Diet, Fatty Acids, Unsaturated, Humans, Periodontitis, Vitamin D, Vitamins, Micronutrients, Dietary Supplements, Nutrigenomics

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