Differential expression of microRNAs in hematopoietic cell lineages
Open accessAbstract
Objectives: MicroRNAs (miRNAs) play key roles in a wide variety of normal and pathological cellular processes. A number of studies identified hematopoietic‐specific miRNAs that are necessary for correct function of blood cells. Out of our microarray data, we chose 13 miRNAs that showed differential expression in peripheral blood cells (miR‐15b, miR‐16, miR‐24, miR‐30c, miR‐106b, miR‐142‐3p, miR‐142‐5p, miR‐150, miR‐155, miR‐181, miR‐223, miR‐342, and miR‐451) and examined their expression in separated hematopoietic cell lineages. Methods: Using quantitative real‐time polymerase chain reaction, we measured relative expression of the miRNAs in fractions of reticulocytes, platelets, granulocytes, monocytes, B‐ and T‐lymphocytes as well as in several hematopoietic cell lines. Results: We observed that miR‐16 and miR‐142‐3p were highly expressed in all native cell lineages, miR‐451 reached the maximal expression in reticulocytes, miR‐223 in platelets, granulocytes and monocytes, and miR‐150 in B‐ and T‐lymphocytes. Hierarchical clustering analysis grouped the lineage samples according to their origin based on the expression of these miRNAs. To validate discrimination power of the miRNAs, we quantified expression of the 13 miRNAs in several immortalized cell lines. Although the cell lines showed miRNA expression patterns considerably different from those of native cell lineages, clustering analysis distinguished between myeloid, lymphoid and non‐hematopoietic cells. Conclusions: In conclusion, the study reports the expression levels of 13 miRNAs in particular blood cell lineages as well as immortalized cell lines. We demonstrate that the expression profiles of these miRNAs may be used for discrimination of the hematopoietic cell lineages.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
Livak, K. J., & Schmittgen, T. D. (2001) · Methods · doi:10.1006/meth.2001.1262 · Cited by 180,860 · see citing works
Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714 · see citing works
A microRNA expression signature of human solid tumors defines cancer gene targets
Volinia, S., Calin, G. A., Liu, C.-G., Ambs, S., Cimmino, A., Petrocca, F., Visone, R., Iorio, M., Roldo, C., Ferracin, M., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510565103 · Cited by 5,697 · see citing works
Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., Aldler, H., Rattan, S., Keating, M., Rai, K., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242606799 · Cited by 4,269 · see citing works
MicroRNAs Modulate Hematopoietic Lineage Differentiation
Chen, C.-Z., Li, L., Lodish, H. F., & Bartel, D. P. (2004) · Science · doi:10.1126/science.1091903 · Cited by 3,257 · see citing works
Identification of hundreds of conserved and nonconserved human microRNAs
Bentwich, I., Avniel, A., Karov, Y., Aharonov, R., Gilad, S., Barad, O., Barzilai, A., Einat, P., Einav, U., Meiri, E., et al. (2005) · Nature Genetics · doi:10.1038/ng1590 · Cited by 1,465 · see citing works
The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism
Xu, P., Vernooy, S. Y., Guo, M., & Hay, B. A. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00250-1 · Cited by 1,006 · see citing works
A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans
Johnston, R. J., & Hobert, O. (2003) · Nature · doi:10.1038/nature02255 · Cited by 760 · see citing works
Zhou, B., Wang, S. Y., Mayr, C., Bartel, D. P., & Lodish, H. F. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702409104 · Cited by 609 · see citing works
Li, J., Smyth, P. C., Flavin, R., Cahill, S., Denning, K. M., Aherne, S. T., Guenther, S. M., O’Leary, J. J., & Sheils, O. M. (2007) · BMC Biotechnology · doi:10.1186/1472-6750-7-36 · Cited by 344 · see citing works
Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysisPreprint
Berezikov, E., van Tetering, G., Verheul, M., van de Belt, J., Laake, L. W. V., Vos, J. B., Verloop, R. E., van de Wetering, M., Guryev, V., Takada, S., et al. (2006) · Genome Research · doi:10.1101/gr.5159906 · Cited by 269 · see citing works
Hematopoietic-specific microRNA expression in human cells
Ramkissoon, S. H., Mainwaring, L. A., Ogasawara, Y., Keyvanfar, K., McCoy, J. P., Sloand, E. M., Kajigaya, S., & Young, N. S. (2005) · Leukemia Research · doi:10.1016/j.leukres.2005.09.001 · Cited by 241 · see citing works
Expression patterns of microRNAs 155 and 451 during normal human erythropoiesis
Masaki, S., Ohtsuka, R., Abe, Y., Muta, K., & Umemura, T. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.10.077 · Cited by 205 · see citing works
Regulated expression of microRNAs in normal and polycythemia vera erythropoiesis
Bruchova, H., Yoon, D., Agarwal, A. M., Mendell, J., & Prchal, J. T. (2007) · Experimental Hematology · doi:10.1016/j.exphem.2007.08.021 · Cited by 176 · see citing works
Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells
Kasashima, K., Nakamura, Y., & Kozu, T. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.07.130 · Cited by 155 · see citing works
Aberrant expression of microRNA in polycythemia vera
Bruchova, H., Merkerová, M. D., & Prchal, J. T. (2008) · Haematologica · doi:10.3324/haematol.12706 · Cited by 138 · see citing works
Self-citationMicroRNA-155 Function in B Cells
Calame, K. L. (2007) · Immunity · doi:10.1016/j.immuni.2007.11.010 · Cited by 120 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Physiological and pathological roles for microRNAs in the immune system
O’Connell, R. M., Rao, D. S., Chaudhuri, A. A., & Baltimore, D. (2010) · Nature reviews. Immunology · doi:10.1038/nri2708 · Cited by 1,538 · see citing works
MicroRNA Control in the Immune System: Basic Principles
Xiao, C., & Rajewsky, K. (2009) · Cell · doi:10.1016/j.cell.2008.12.027 · Cited by 1,008 · see citing works
Haemolysis during sample preparation alters microRNA content of plasma
Kirschner, M. B., Kao, S. C., Edelman, J. J., Armstrong, N. J., Vallely, M. P., van Zandwijk, N., & Reid, G. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024145 · Cited by 498 · see citing works
Existence of a microRNA pathway in anucleate platelets
Landry, P., Plante, I., Ouellet, D. L., Perron, M. P., Rousseau, G., & Provost, P. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1651 · Cited by 485 · see citing works
Circulating microRNAs: Association with disease and potential use as biomarkers
Reid, G., Kirschner, M. B., & van Zandwijk, N. (2010) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2010.11.004 · Cited by 465 · see citing works
Expression Profile of MicroRNAs in Young Stroke Patients
Tan, K. S., Armugam, A., Sepramaniam, S., Lim, K. Y., Karolina, D. S., Wang, C. W., & Jeyaseelan, K. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007689 · Cited by 396 · see citing works
Hanson, E., Lubenow, H., & Ballantyne, J. (2009) · Analytical Biochemistry · doi:10.1016/j.ab.2009.01.037 · Cited by 379 · see citing works
Keller, A., Leidinger, P., Lange, J., Borries, A., Schrörs, H., Scheffler, M., Lenhof, H., Ruprecht, K., & Meese, E. U. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007440 · Cited by 365 · see citing works
MicroRNA expression profiles predictive of human renal allograft status
Anglicheau, D., Sharma, V. K., Ding, R., Hummel, A., Snopkowski, C., Dadhania, D. M., Seshan, S. V., & Suthanthiran, M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813121106 · Cited by 337 · see citing works
Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity
Nagalla, S., Shaw, C. A., Kong, X., Kondkar, A. A., Edelstein, L. C., Ma, L., Chen, J., McKnight, G. S., López, J. A., Yang, L., et al. (2011) · Blood · doi:10.1182/blood-2010-09-299719 · Cited by 327 · see citing works
Regulation of MicroRNA Expression and Abundance during Lymphopoiesis
Kuchen, S., Resch, W., Yamane, A., Kuo, N., Li, Z., Chakraborty, T., Wei, L., Laurence, A. D. J., Yasuda, T., Peng, S., et al. (2010) · Immunity · doi:10.1016/j.immuni.2010.05.009 · Cited by 324 · see citing works
Finnerty, J. R., Wang, W.-X., Hébert, S. S., Wilfred, B. R., Mao, G., & Nelson, P. T. (2010) · Journal of Molecular Biology · doi:10.1016/j.jmb.2010.07.051 · Cited by 321 · see citing works
Gidlöf, O., van der Brug, M., Öhman, J. N., Gilje, P., Olde, B., Wahlestedt, C., & Erlinge, D. (2013) · Blood · doi:10.1182/blood-2012-10-461798 · Cited by 273 · see citing works
miR-451 protects against erythroid oxidant stress by repressing 14-3-3ζPreprint
Yu, D., dos Santos, C. O., Zhao, G., Jiang, J., Amigo, J. D., Khandros, E., Doré, L. C., Yao, Y., D'Souza, J., Zhang, Z., et al. (2010) · Genes & Development · doi:10.1101/gad.1942110 · Cited by 234 · see citing works
Role of microRNAs in the immune system, inflammation and cancer
Raisch, J. (2013) · World Journal of Gastroenterology · doi:10.3748/wjg.v19.i20.2985 · Cited by 204 · see citing works
The microRNA network and tumor metastasis
Zhang, H., Li, Y., & Lai, M. (2009) · Oncogene · doi:10.1038/onc.2009.406 · Cited by 185 · see citing works
Targeting microRNAs as key modulators of tumor immune response
Paladini, L., Fabris, L., Bottai, G., Raschioni, C., Călin, G. A., & Santarpia, L. (2016) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-016-0375-2 · Cited by 183 · see citing works
Lv, M., Zhang, X., Jia, H., Li, D., Zhang, B., Zhang, H., Hong, M., Jiang, T., Jiang, Q., Lu, J., et al. (2011) · Leukemia · doi:10.1038/leu.2011.273 · Cited by 173 · see citing works
The role of microRNA-150 as a tumor suppressor in malignant lymphoma
Watanabe, A., Tagawa, H., Yamashita, J., Teshima, K., Nara, M., Iwamoto, K., Kume, M., Kameoka, Y., Takahashi, N., Nakagawa, T., et al. (2011) · Leukemia · doi:10.1038/leu.2011.81 · Cited by 172 · see citing works
MicroRNAs of the immune system
Davidson-Moncada, J. K., Papavasiliou, F. N., & Tam, W. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05121.x · Cited by 171 · see citing works
Immuno‐miRs: critical regulators of T‐cell development, function and ageing
Kroesen, B., Teteloshvili, N., Smigielska‐Czepiel, K., Brouwer, E., Boots, A. M. H., van den Berg, A., & Kluiver, J. L. (2014) · Immunology · doi:10.1111/imm.12367 · Cited by 168 · see citing works
Scian, M. J., Maluf, D. G., David, K. G., Archer, K. J., Suh, J. L., Wolen, A. R., Mba, M. U., Massey, H. D., King, A. L., Gehr, T. W. B., et al. (2011) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2011.03666.x · Cited by 167 · see citing works
Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood
Vaz, C., Ahmad, H. M., Sharma, P., Gupta, R., Kumar, L., Kulshreshtha, R., & Bhattacharya, A. (2010) · BMC Genomics · doi:10.1186/1471-2164-11-288 · Cited by 144 · see citing works
MicroRNA dysregulation in spinal cord injury: causes, consequences and therapeutics
Nieto‐Díaz, M., Esteban, F. J., Reigada, D., Muñoz‐Galdeano, T., Yunta, M., Caballero-López, M. J., Navarro-Ruíz, R., del Águila, Á., & Maza, R. M. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00053 · Cited by 135 · see citing works
A Critical Evaluation of microRNA Biomarkers in Non-Neoplastic Disease
Haider, B. A., Baras, A. S., McCall, M. N., Hertel, J. A., Cornish, T. C., & Halushka, M. K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089565 · Cited by 133 · see citing works
Shi, L., Fißlthaler, B., Zippel, N., Frömel, T., Hu, J., Elgheznawy, A., Heide, H., Popp, R., & Fleming, I. (2013) · Circulation Research · doi:10.1161/circresaha.113.301824 · Cited by 127 · see citing works
Jeon, Y. J., Kim, O. J., Kim, S. Y., Oh, S. H., Oh, D., Kim, O. J., Shin, B. S., & Kim, N. K. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.300251 · Cited by 124 · see citing works
Expression and Rhythmic Modulation of Circulating MicroRNAs Targeting the Clock Gene Bmal1 in Mice
Shende, V. R., Goldrick, M. M., Ramani, S., & Earnest, D. J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022586 · Cited by 121 · see citing works
MicroRNAs in platelet production and activation
Edelstein, L. C., & Bray, P. F. (2011) · Blood · doi:10.1182/blood-2011-01-292011 · Cited by 120 · see citing works
MicroRNAs in vascular aging and atherosclerosis
Menghini, R., Stöhr, R., & Federici, M. (2014) · Ageing Research Reviews · doi:10.1016/j.arr.2014.03.005 · Cited by 117 · see citing works
miR-142-3p Is a Key Regulator of IL-1β-Dependent Synaptopathy in Neuroinflammation
Mandolesi, G., Vito, F. D., Musella, A., Gentile, A., Bullitta, S., Fresegna, D., Sepman, H., Sanza, C. D., Haji, N., Mori, F., et al. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.0851-16.2016 · Cited by 116 · see citing works
Kagiya, T., & Nakamura, S. (2012) · Journal of Periodontal Research · doi:10.1111/jre.12017 · Cited by 113 · see citing works
Denecke, B., Rostalsky, A., Hristov, M., Koeppel, T. A., Bidzhekov, K., Gan, L., Zernecke, A., & Weber, C. (2012) · Thrombosis and Haemostasis · doi:10.1160/th11-09-0607 · Cited by 112 · see citing works
Haller, F., von Heydebreck, A., Zhang, J. D., Gunawan, B., Langer, C., Ramadori, G. P., Wiemann, S., & Şahin, Ö. (2009) · The Journal of Pathology · doi:10.1002/path.2610 · Cited by 112 · see citing works
Danger, R., Pallier, A., Giral, M., Martínez‐Llordella, M., Lozano, J. J., Degauque, N., Fueyo, A. S., Soulillou, J., & Brouard, S. (2012) · Journal of the American Society of Nephrology · doi:10.1681/asn.2011060543 · Cited by 111 · see citing works
Dicer Cleavage by Calpain Determines Platelet microRNA Levels and Function in Diabetes
Elgheznawy, A., Shi, L., Hu, J., Wittig, I., Laban, H., Pircher, J., Mann, A. W., Provost, P., Randriamboavonjy, V., & Fleming, I. (2015) · Circulation Research · doi:10.1161/circresaha.117.305784 · Cited by 109 · see citing works
The Potential Role of miR-451 in Cancer Diagnosis, Prognosis, and Therapy
Pan, X., Wang, R., & Wang, Z.-X. (2013) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-12-0802 · Cited by 108 · see citing works
Osman, A., & Fälker, K. (2011) · Platelets · doi:10.3109/09537104.2011.560305 · Cited by 103 · see citing works
Hally, K. E., Fauteux‐Daniel, S., Hamzeh‐Cognasse, H., Larsen, P., & Cognasse, F. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21176150 · Cited by 101 · see citing works
Sondermeijer, B. M., Bakker, A., Halliani, A., de Ronde, M. W. J., Marquart, A. A., Tijsen, A. J., Mulders, T. A., Kok, M. G. M., Battjes, S., Maiwald, S., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025946 · Cited by 100 · see citing works
Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets
Rowley, J. W., Chappaz, S., Corduan, A., Chong, M. M. W., Campbell, R. A., Khoury, A., Manne, B. K., Wurtzel, J. G. T., Michael, J. V., Goldfinger, L. E., et al. (2016) · Blood · doi:10.1182/blood-2015-07-661371 · Cited by 99 · see citing works
Rahmani, A., Saleki, K., Javanmehr, N., Javad, K., Saadat, P., & Nouri, H. R. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101106 · Cited by 97 · see citing works
Dewi, I. S., Celik, S., Karlsson, A., Hollander, Z., Lam, K., McManus, J. E. W., Tebbutt, S. J., Ng, R. T., Keown, P. A., McMaster, R., et al. (2016) · Cardiovascular Research · doi:10.1093/cvr/cvw244 · Cited by 94 · see citing works
Considerations and Suggestions for the Reliable Analysis of miRNA in Plasma Using qRT-PCR
Ban, E., & Song, E. J. (2022) · Genes · doi:10.3390/genes13020328 · Cited by 94 · see citing works
miR-29a and miR-142-3p downregulation and diagnostic implication in human acute myeloid leukemia
Wang, F., Wang, X., Yang, G., Zhai, P.-F., Xiao, Z., Xia, L., Chen, L., Wang, Y., Wang, X., Bi, L., et al. (2011) · Molecular Biology Reports · doi:10.1007/s11033-011-1026-5 · Cited by 91 · see citing works
Teruel‐Montoya, R., Kong, X., Abraham, S., Ma, L., Kunapuli, S. P., Holinstat, M. A., Shaw, C. A., McKenzie, S. E., Edelstein, L. C., & Bray, P. F. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102259 · Cited by 90 · see citing works
The urine microRNA profile may help monitor post-transplant renal graft function
Maluf, D. G., Dumur, C. I., Suh, J. L., Scian, M. J., King, A. L., Cathro, H. P., Lee, J. K., Gehrau, R. C., Brayman, K. L., Gallon, L. G., et al. (2013) · Kidney International · doi:10.1038/ki.2013.338 · Cited by 87 · see citing works
MicroRNA-145 Regulates Human Corneal Epithelial Differentiation
Lee, S. K.-W., Teng, Y., Wong, H.-K., Ng, T. K., Huang, L., Peng, L., Choy, K. W., Liu, Y., Zhang, M., Lam, D. S.-C., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021249 · Cited by 86 · see citing works
Retinoic acid induces HL-60 cell differentiation via the upregulation of miR-663
Jian, P., Li, Z. W., Fang, T., Wang, J., Zhuan, Z., Mei, L. X., Yan, W. S., & Jian, N. (2011) · Journal of Hematology & Oncology · doi:10.1186/1756-8722-4-20 · Cited by 86 · see citing works
MicroRNA Expression Profiles in Umbilical Cord Blood Cell Lineages
Merkerová, M. D., Vašíková, A., Beličková, M., & Votavová, H. (2009) · Stem Cells and Development · doi:10.1089/scd.2009.0071 · Cited by 86 · see citing works
Li, L., Hou, D., Guo, Y.-L., Yang, J., Liu, Y., Zhang, C., & Zen, K. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1001633 · Cited by 83 · see citing works
Alshatwi, A. A., Shafi, G., Hasan, T. N., Syed, N. A., Al‐Hazzani, A. A., Alsaif, M. A., & Alsaif, A. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030049 · Cited by 81 · see citing works
miR-142 orchestrates a network of actin cytoskeleton regulators during megakaryopoiesis
Chapnik, E., Rivkin, N., Mildner, A., Beck, G., Pasvolsky, R., Metzl-Raz, E., Birger, Y., Amir, G., Tirosh, I., Porat, Z., et al. (2014) · eLife · doi:10.7554/elife.01964 · Cited by 79 · see citing works
MicroRNA-96 Directly Inhibits γ-Globin Expression in Human Erythropoiesis
Azzouzi, I., Moest, H., Winkler, J., Fauchère, J., Gerber, A. P., Wollscheid, B., Stoffel, M., Schmugge, M., & Speer, O. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022838 · Cited by 79 · see citing works
Awwad, K., Hu, J., Shi, L., Mangels, N., Abdel Malik, R., Zippel, N., Fisslthaler, B., Eble, J. A., Pfeilschifter, J., Popp, R., et al. (2015) · Cardiovascular Research · doi:10.1093/cvr/cvv098 · Cited by 77 · see citing works
Merkerová, M. D., Krejčík, Z., Votavová, H., Beličková, M., Vašíková, A., & Čermák, J. (2010) · European Journal of Human Genetics · doi:10.1038/ejhg.2010.209 · Cited by 76 · see citing works
Gieni, R. S., & Hendzel, M. J. (2009) · Biochemistry and Cell Biology · doi:10.1139/o09-057 · Cited by 74 · see citing works
Yamakuchi, M. (2012) · International Journal of Vascular Medicine · doi:10.1155/2012/794898 · Cited by 73 · see citing works
Pre-Micro RNA Signatures Delineate Stages of Endothelial Cell Transformation in Kaposi Sarcoma
O’Hara, A. J., Chugh, P., Wang, L., Netto, E. M., Luz, E., Harrington, W. J., Dezube, B. J., Damania, B., & Dittmer, D. P. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000389 · Cited by 72 · see citing works
Chaudhuri, A. D., Yelamanchili, S. V., Marcondes, M. C. G., & Fox, H. S. (2013) · The FASEB Journal · doi:10.1096/fj.13-232678 · Cited by 67 · see citing works
Wang, F., Liang, R., Tandon, N., Matthews, E. R., Shrestha, S., Yang, J., Soibam, B., Yang, J., & Liu, Y. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2971-0 · Cited by 71 · see citing works
Expression of miR-15/107 Family MicroRNAs in Human Tissues and Cultured Rat Brain Cells
Wang, W.-X., Danaher, R. J., Miller, C. S., Berger, J. R., Nubia, V. G., Wilfred, B. S., Neltner, J. H., Norris, C. M., & Nelson, P. T. (2014) · Genomics, Proteomics & Bioinformatics · doi:10.1016/j.gpb.2013.10.003 · Cited by 67 · see citing works
Regulation of Neutrophil Senescence by MicroRNAs
Ward, J. R., Heath, P. R., Catto, J. W. F., Whyte, M. K. B., Milo, M., & Renshaw, S. A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0015810 · Cited by 67 · see citing works
Pulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage
Halappanavar, S. S., Wu, D., Williams, A., Kuo, B. Y.-L., Godschalk, R., van Schooten, F., & Yauk, C. L. (2011) · Toxicology · doi:10.1016/j.tox.2011.04.011 · Cited by 67 · see citing works
Trissal, M. C., Wong, T. N., Yao, J.-C., Ramaswamy, R., Kuo, I., Baty, J., Sun, Y., Jih, G. T., Parikh, N., Berrien-Elliott, M. M., et al. (2018) · Cancer Research · doi:10.1158/0008-5472.can-17-3592 · Cited by 66 · see citing works
Hand, N. J., Horner, A. M., Master, Z. R., Boateng, L. A., Guen, C. L. L., Uvaydova, M., & Friedman, J. R. (2011) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e318244148b · Cited by 66 · see citing works
Differential expression of microRNAs in Marek's disease virus-transformed T-lymphoma cell lines
Yao, Y., Zhao, Y., Smith, L. P., Lawrie, C. H., Saunders, N. J. S. G., Watson, M., & Nair, V. (2009) · Journal of General Virology · doi:10.1099/vir.0.009902-0 · Cited by 64 · see citing works
MicroRNAs in Platelet Biogenesis and Function: Implications in Vascular Homeostasis and Inflammation
Gatsiou, A., Boeckel, J., Randriamboavonjy, V., & Stellos, K. (2012) · Current Vascular Pharmacology · doi:10.2174/157016112801784611 · Cited by 63 · see citing works
Manoharan, P., Basford, J. E., Pilcher-Roberts, R., Neumann, J. C., Hui, D. Y., & Lingrel, J. B. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.579763 · Cited by 61 · see citing works
MicroRNAs in hematological malignancies
Lawrie, C. H. (2013) · Blood Reviews · doi:10.1016/j.blre.2013.04.002 · Cited by 61 · see citing works
Immunosenescence-Associated Micrornas in Age and Heart Failure
Seeger, T., Haffez, F., Fischer, A., Koehl, U., Leistner, D. M., Seeger, F. H., Boon, R. A., Zeiher, A. M., & Dimmeler, S. (2012) · European Journal of Heart Failure · doi:10.1093/eurjhf/hfs184 · Cited by 60 · see citing works
Kannan, M., Mohan, K. V. K., Kulkarni, S., & Atreya, C. D. (2009) · Transfusion · doi:10.1111/j.1537-2995.2009.02140.x · Cited by 60 · see citing works
Involvement of MicroRNA in T-Cell Differentiation and Malignancy.
Saki, N., Abroun, S., Soleimani, M., Hajizamani, S., Shahjahani, M., Kast, R. E., & Mortazavi, Y. (2015) · Europe PMC (PubMed Central) · Cited by 58 · see citing works
Leidinger, P., Backes, C., Dahmke, I. N., Galata, V., Huwer, H., Stehle, I., Bals, R., Keller, A., & Meese, E. U. (2014) · Oncotarget · doi:10.18632/oncotarget.2419 · Cited by 58 · see citing works
Immunomodulation: A definitive role of microRNA-142
Sharma, S. (2017) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2017.08.001 · Cited by 58 · see citing works
Soltaninejad, E., Nicknam, M. H., Nafar, M., Ahmadpoor, P., Pour-Reza-Gholi, F., Sharbafi, M. H., Hosseinzadeh, M., Foroughi, F., Yekaninejad, M. S., Bahrami, T., et al. (2015) · Transplant Immunology · doi:10.1016/j.trim.2015.05.002 · Cited by 57 · see citing works
Pan-cancer analysis of somatic mutations in miRNA genes
Urbanek-Trzeciak, M. O., Galka-Marciniak, P., Nawrocka, P. M., Kowal-Wiśniewska, E., Szwec, S., Giefing, M., & Kozłowski, P. (2020) · EBioMedicine · doi:10.1016/j.ebiom.2020.103051 · Cited by 56 · see citing works
Prognostic Role of MicroRNA-181a/b in Hematological Malignancies: A Meta-Analysis
Lin, S., Pan, L., Guo, S., Wu, J., Li, J., Wang, J., & Wang, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0059532 · Cited by 56 · see citing works
Cai, L., Gong, C., Li, W., Zhu, J., Li, F., Qi, B., Wei, Y. X., Chen, S., Zhou, G., Lu, X., et al. (2020) · Aging · doi:10.18632/aging.103084 · Cited by 56 · see citing works
microRNAs as Promising Biomarkers of Platelet Activity in Antiplatelet Therapy Monitoring
Krammer, T. L., Mayr, M., & Hackl, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21103477 · Cited by 55 · see citing works
microRNA expression in erythropoiesis and erythroid disorders
Lawrie, C. H. (2009) · British Journal of Haematology · doi:10.1111/j.1365-2141.2009.07978.x · Cited by 54 · see citing works
Glémain, A., Néel, M., Néel, A., André‐Grégoire, G., Gavard, J., Martinet, B., Bloas, R. L., Riquin, K., Hamidou, M. A., Fakhouri, F., et al. (2022) · Journal of Autoimmunity · doi:10.1016/j.jaut.2022.102826 · Cited by 53 · see citing works
MicroRNAs, Major Players in B Cells Homeostasis and Function
Danger, R., Braza, F., Giral, M., Soulillou, J., & Brouard, S. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00098 · Cited by 53 · see citing works
Diagnostic microRNAs in myelodysplastic syndrome
Erdoğan, B., Facey, C., Qualtieri, J. N., Tedesco, J., Rinker, E. B., Isett, R. B., Tobias, J. W., Baldwin, D. A., Thompson, J. E., Carroll, M. P., et al. (2011) · Experimental Hematology · doi:10.1016/j.exphem.2011.06.002 · Cited by 53 · see citing works
Activating stimuli induce platelet microRNA modulation and proteome reorganisation
Nassa, G., Filippo, M. D., Giurato, G., Ravo, M., Rizzo, F. M., Conte, S., Pellegrino, G., Cirillo, P. L., Calabrò, P., Öhman, T., et al. (2015) · Thrombosis and Haemostasis · doi:10.1160/th14-09-0726 · Cited by 51 · see citing works
Mortarino, M., Gioia, G., Gelain, M. E., Albonico, F., Roccabianca, P., Ferri, E., & Comazzi, S. (2009) · Leukemia Research · doi:10.1016/j.leukres.2009.10.023 · Cited by 51 · see citing works
A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset
Selimoglu‐Buet, D., Rivière, J., Ghamlouch, H., Bencheikh, L., Lacout, C., Morabito, M., Diop, M. K., Meurice, G., Breckler, M., Chauveau, A., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-07801-x · Cited by 51 · see citing works
The distribution of circulating microRNA and their relation to coronary disease
Freedman, J. E., Ercan, B., Morin, K. M., Liu, C., Tamer, L., Ayaz, L., Kanadaşı, M., Çiçek, D., Seyhan, A. I., Akıllı, R. E., et al. (2012) · F1000Research · doi:10.12688/f1000research.1-50.v1 · Cited by 48 · see citing works
Lagrange, B., Martin, R. Z., Droin, N. M., Aucagne, R., Paggetti, J., Largeot, A., Itzykson, R., Solary, É., Delva, L., & Bastie, J.-N. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2013.04.007 · Cited by 48 · see citing works
MicroRNA-142-5p contributes to Hashimoto’s thyroiditis by targeting CLDN1
Zhu, J., Zhang, Y., Zhang, W., Zhang, W., Fan, L., Wang, L., Liu, Y., Liu, S., Guo, Y., Wang, Y., et al. (2016) · Journal of Translational Medicine · doi:10.1186/s12967-016-0917-6 · Cited by 48 · see citing works
Aberrant micro RNA expression in multiple myeloma
Dimopoulos, K., Gimsing, P., & Grønbæk, K. (2013) · European Journal Of Haematology · doi:10.1111/ejh.12124 · Cited by 47 · see citing works
Differential Regulation of microRNAs in Patients with Ischemic Stroke
Li, S., Su, S., & Liu, J. (2015) · Current Neurovascular Research · doi:10.2174/1567202612666150605121709 · Cited by 47 · see citing works
HTLV-1/-2 and HIV-1 co-infections: retroviral interference on host immune status
Pilotti, E., Bianchi, M. V., Maria, A. D., Bozzano, F. M., Romanelli, M. G., Bertazzoni, U., & Casoli, C. (2013) · Frontiers in Microbiology · doi:10.3389/fmicb.2013.00372 · Cited by 45 · see citing works
Sweeney, C. L., Teng, R., Wang, H., Merling, R. K., Lee, J. S., Choi, U., Koontz, S. M., Wright, D. G., & Malech, H. L. (2016) · Stem Cells · doi:10.1002/stem.2332 · Cited by 45 · see citing works
Li, X. H., Ha, C. T., Fu, D., & Xiao, M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0048700 · Cited by 44 · see citing works
HOXA9 regulates miR-155 in hematopoietic cells
Hu, Y., Fong, S., Largman, C., & Shen, W.-F. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq337 · Cited by 43 · see citing works
Miceli, G., Basso, M. G., Rizzo, G., Pintus, C., & Tuttolomondo, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232314914 · Cited by 42 · see citing works
Identification and Characterization of MicroRNAs in the Spleen of Common Carp Immune Organ
Li, G., Zhao, Y., Wen, L., Liu, Z., Yan, F., & Gao, C. (2014) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24843 · Cited by 42 · see citing works
Hussein, K., Theophile, K., Dralle, W., Wiese, B., Kreipe, H. H., & Bock, O. (2009) · Platelets · doi:10.1080/09537100903114537 · Cited by 42 · see citing works
Wu, J., Zhang, Y.-C., Suo, W.-H., Liu, X.-B., Shen, W.-W., Tian, H., & Fu, G. (2010) · Oncogene · doi:10.1038/onc.2009.481 · Cited by 41 · see citing works
- Authors
- Merkerova, M., Belickova, M., & Bruchova, H.
- Venue
- European Journal of Haematology
- Publisher
- Wiley
- Published
- 2008-09-15
- Volume
- 81
- Issue
- 4
- Pages
- 304-310
- ISSN
- 0902-4441 (ISSN-L)
- 1600-0609
- OpenAlex
- W2077066570
- Cited by
- 240
- References
- 17
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 4 · 2023: 7 · 2022: 6 · 2021: 10 · 2020: 9 · 2019: 13 · 2018: 10 · 2017: 8 · 2016: 19 · 2015: 14 · 2014: 19 · 2013: 29 · 2012: 25
- FWCI
- 6.92
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Journal Of Haematology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministerstvo Zdravotnictví Ceské Republiky
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › MicroRNA in disease regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gene expression and cancer classification
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Keywords
- microRNA, hematopoietic lineage, miR-150, miR-155, miR-142-3p, miR-142-5p, miR-223, miR-451, miR-16, miR-15b, miR-15b-5p, miR-106b, miR-24, miR-30c, miR-342, miR-181, miR-30c-5p, reticulocytes, platelets, granulocytes, monocytes, B cells, T cells, hematopoietic cell lines, gene expression profiling
- MeSH terms
- Blood Platelets, Cell Differentiation, Gene Expression Regulation, HeLa Cells, Humans, Leukocytes, Reticulocytes, K562 Cells, Oligonucleotide Array Sequence Analysis, Gene Expression Profiling, MicroRNAs, Granulocyte Precursor Cells, Lymphoid Progenitor Cells
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
