The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Tumor‐induced tolerance and immune suppression by myeloid derived suppressor cells
Abstract
Summary: Emerging evidence indicates that the Achilles' heel of cancer immunotherapies is often the complex interplay of tumor‐derived factors and deviant host properties, which involve a wide range of immune elements in the lymphoid and myeloid compartments. Regulatory lymphocytes, tumor‐conditioned myeloid‐derived suppressor cells (MDSCs), tumor‐associated macrophages, and dysfunctional and immature dendritic cells take part in a complex immunoregulatory network. Despite the fact that some mechanisms governing tumor‐induced immune tolerance and suppression are starting to be better understood and their complexity dissected, little is known about the diachronic picture of immune tolerance. Based on observations of MDSCs, we present a time‐structured and topologically consistent idea of tumor‐dependent tolerance progression in tumor‐bearing hosts.
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Ido expression by dendritic cells: tolerance and tryptophan catabolism
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Self-citationCancer despite immunosurveillance: immunoselection and immunosubversion
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Cited by
Cancer immunotherapy comes of age
Mellman, I., Coukos, G., & Dranoff, G. (2011) · Nature · doi:10.1038/nature10673 · Cited by 3,893
Microenvironmental regulation of metastasis
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Immune evasion in cancer: mechanistic basis and therapeutic strategies
Vinay, D. S., Ryan, E. P., Pawelec, G., Talib, W. H., Stagg, J., Elkord, E., Lichtor, T., Decker, W. K., Whelan, R. L., Kumara, H. M. C. S., et al. (2015) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2015.03.004 · Cited by 1,625
Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells
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Metadata
- Authors
- Marigo, I., Dolcetti, L., Serafini, P., Zanovello, P., & Bronte, V.
- Venue
- Immunological Reviews
- Publisher
- Wiley
- Published
- 2008-03-19
- Volume
- 222
- Issue
- 1
- Pages
- 162-179
- ISSN
- 0105-2896 (ISSN-L)
- 1600-065X
- OpenAlex
- W2053829861
- Cited by
- 608
- References
- 16
- FWCI
- 3.11
- Type
- journal article
- Language
- en
- Open access
- closed
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- Marigo, I., Dolcetti, L., Serafini, P., Zanovello, P., & Bronte, V. (2008). Tumor‐induced tolerance and immune suppression by myeloid derived suppressor cells. Immunological Reviews. https://doi.org/10.1111/j.1600-065x.2008.00602.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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