The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Activation of gelatinolytic/collagenolytic activity in dentin by self‐etching adhesives
Abstract
Mild acids are known to activate dentin matrix metalloproteinase (MMPs). All self‐etching dental adhesives are acidic (pH 1.5–2.7) and may activate dentin MMPs. The purpose of this study was to compare the ability of several all‐in‐one adhesives to activate gelatinolytic and collagenolytic activities in powdered mineralized dentin. Powdered dentin made from human teeth was mixed with all‐in‐one adhesives (Clearfil Tri‐S Bond, G‐Bond, Adper Prompt L‐Pop) or a self‐etching primer (Clearfil SE Bond primer) for varying times and then the reaction was stopped by extracting the adhesives using acetone. Fresh untreated mineralized dentin powder had a gelatinolytic activity of 3.31 ± 0.39 relative fluorescent units (RFU) per mg dry weight (24 h) that increased, over storage time, to 87.5 RFU mg−1 (24 h) after 6–8 wk. When fresh powder was treated with acidic Tri‐S Bond, the gelatinolytic activity increased from 3.24 ± 0.70 RFU mg−1 to > 112.5 RFU mg−1 (24 h) after 20 min and then remained unchanged. Monomers with lower pH values produced less activity. There was a significant, direct correlation between gelatinolytic activity and pH, with Tri‐S giving the highest activity. Coating dentin powder with Tri‐S resin prevented fluorescent substrates from gaining access to the enzyme, even though it activated the enzyme. In conclusion, self‐etch adhesives may activate latent MMP and increase the activity to near‐maximum levels and contribute to the degradation of resin–dentin bonds over time.
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Collagen Degradation by Host-derived Enzymes during Aging
Pashley, D. H., Tay, F. R., Yiu, C., Hashimoto, M., Breschi, L., Carvalho, R. M., & Ito, S. (2004) · Journal of Dental Research · doi:10.1177/154405910408300306 · Cited by 1,123
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Self-citationEffects of resin hydrophilicity on water sorption and changes in modulus of elasticity
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Self-citationInhibition of the Activities of Matrix Metalloproteinases 2, 8, and 9 by Chlorhexidine
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Chlorhexidine Arrests Subclinical Degradation of Dentin Hybrid Layers in vivo
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The matrix metalloproteinase gelatinase A in human dentine
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The Localization of Matrix Metalloproteinase-20 (MMP-20, Enamelysin) in Mature Human Teeth
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Self-citationThe effects of MMP inhibitors on human salivary MMP activity and caries progression in rats
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Tjäderhane, L., Buzalaf, M. A. R., Carrilho, M., & Chaussain, C. (2015) · Caries Research · doi:10.1159/000363582 · Cited by 2,306
Self-citationLimitations in bonding to dentin and experimental strategies to prevent bond degradation
Liu, Y., Tjäderhane, L., Breschi, L., Mazzoni, A., Li, N., Mao, J., Pashley, D. H., & Tay, F. R. (2011) · Journal of Dental Research · doi:10.1177/0022034510391799 · Cited by 665
Self-citationRole of dentin MMPs in caries progression and bond stability
Mazzoni, A., Tjäderhane, L., Checchi, V., Di Lenarda, R., Salo, T., Tay, F. R., Pashley, D. H., & Breschi, L. (2015) · Journal of Dental Research · doi:10.1177/0022034514562833 · Cited by 429
Self-citationStrategies to prevent hydrolytic degradation of the hybrid layer—A review
Tjäderhane, L., Nascimento, F. D., Breschi, L., Mazzoni, A., Tersariol, I. L. S., Geraldeli, S., Tezvergil-Mutluay, A., Carrilho, M., Carvalho, R. M., Tay, F. R., et al. (2013) · Dental Materials · doi:10.1016/j.dental.2013.07.016 · Cited by 428
Self-citationZymographic Analysis and Characterization of MMP-2 and -9 Forms in Human Sound Dentin
Mazzoni, A., Mannello, F., Tay, F. R., Tonti, G. A. M., Papa, S., Mazzotti, G., Di Lenarda, R., Pashley, D. H., & Breschi, L. (2007) · Journal of Dental Research · doi:10.1177/154405910708600509 · Cited by 329
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Metadata
- Authors
- Nishitani, Y., Yoshiyama, M., Wadgaonkar, B., Breschi, L., Mannello, F., Mazzoni, A., Carvalho, R. M., Tjäderhane, L., Tay, F. R., & Pashley, D. H.
- Venue
- European Journal of Oral Sciences
- Publisher
- Wiley
- Published
- 2006-03-27
- Volume
- 114
- Issue
- 2
- Pages
- 160-166
- ISSN
- 0029-845X (ISSN-L)
- 0909-8836
- 1600-0722
- OpenAlex
- W2109894097
- Cited by
- 375
- References
- 15
- FWCI
- 18.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- Nishitani, Y., Yoshiyama, M., Wadgaonkar, B., Breschi, L., Mannello, F., Mazzoni, A., Carvalho, R. M., Tjäderhane, L., Tay, F. R., & Pashley, D. H. (2006). Activation of gelatinolytic/collagenolytic activity in dentin by self‐etching adhesives. European Journal of Oral Sciences. https://doi.org/10.1111/j.1600-0722.2006.00342.x
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