The DOI matches its Crossref record; 77 of the 77 references it cites were found in a registry or an index.
Regulation of Nuclear Transport: Central Role in Development and Transformation?
Abstract
Transport of macromolecules into and out of the nucleus is generally effected by targeting signals that are recognized by specific members of the importin/exportin transport receptor family. The latter mediate passage through the nuclear envelope‐embedded nuclear pore complexes (NPCs) by conferring interaction with NPC constituents, as well as with other components of the nuclear transport machinery, including the guanine nucleotide‐binding protein Ran. Importantly, nuclear transport is regulated at multiple levels via a diverse range of mechanisms, such as the modulation of the accessibility and affinity of target signal recognition by importins/exportins, with phosphorylation/dephosphorylation as a major mechanism. Alteration of the level of the expression of components of the nuclear transport machinery also appears to be a key determinant of transport efficiency, having central importance in development, differentiation and transformation.
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Cites
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Cited by
The Nuclear Pore Complex and Nuclear Transport
Wente, S. R., & Rout, M. P. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a000562 · Cited by 686
Redox regulation of SIRT1 in inflammation and cellular senescence
Hwang, J.-W., Yao, H., Caito, S., Sundar, I. K., & Rahman, I. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.03.015 · Cited by 503
Types of nuclear localization signals and mechanisms of protein import into the nucleus
Lu, J., Wu, T., Zhang, B., Liu, S., Song, W., Qiao, J., & Ruan, H. (2021) · Cell Communication and Signaling · doi:10.1186/s12964-021-00741-y · Cited by 459
Caito, S., Rajendrasozhan, S., Cook, S., Chung, S., Yao, H., Friedman, A. E., Brookes, P. S., & Rahman, I. (2010) · The FASEB Journal · doi:10.1096/fj.09-151308 · Cited by 294
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Metadata
- Authors
- Poon, I. K. H., & Jans, D. A.
- Venue
- Traffic
- Publisher
- Wiley
- Published
- 2005-01-17
- Volume
- 6
- Issue
- 3
- Pages
- 173-186
- ISSN
- 1398-9219 (ISSN-L)
- 1600-0854
- OpenAlex
- W1480534106
- Cited by
- 360
- References
- 77
- FWCI
- 10.49
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
