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Cited by 358

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Prospective Age-Matching in Elderly Kidney Transplant Recipients—A 5-Year Analysis of the Eurotransplant Senior Program

Open access
Frei, U., Noeldeke, J., Machold-Fabrizii, V., Arbogast, H., Margreiter, R., Fricke, L., Voiculescu, A., Kliem, V., Ebel, H., Albert, U., Lopau, K., Schnuelle, P., Nonnast-Daniel, B., Pietruck, F., Offermann, R., Persijn, G., Bernasconi, C.·2008·American Journal of Transplantation

Abstract

Renal transplantation faces challenges: the organ shortage resulting in extended waiting times and an aging population resulting in death with a functioning graft. The Eurotransplant Senior Program (ESP) allocates kidneys within a narrow geographic area from donors aged >/=65 years to recipients >/=65 years regardless of HLA. This analysis investigates the impact of the ESP on waiting time, graft and patient survival. The ESP group (n = 1406, old to old) was compared to two groups allocated via the Eurotransplant Kidney Allocation System (ETKAS) with either similar donor age (old to any [O/A], donor age >/=65, n = 446) or recipient age (any to old, [A/O], recipient age 60-64, n = 1687). All patients were transplanted between 1999 and 2004. Since initiation of the ESP (1999), availability of elderly donors doubled and waiting time for ESP patients decreased. Local allocation led to shorter cold ischemia time (11.9 vs. >17.0 h, p < 0.001) and less delayed graft function (DGF, ESP 29.7% vs. O/A 36.2%, p = 0.047) but 5-10% higher rejection rates. Graft and patient survival were not negatively affected by the ESP allocation when compared to the standard allocation. The ESP age matching of elderly donors and recipients is an effective allocation system for organs from elderly donors.

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Metadata

Authors
Frei, U., Noeldeke, J., Machold-Fabrizii, V., Arbogast, H., Margreiter, R., Fricke, L., Voiculescu, A., Kliem, V., Ebel, H., Albert, U., Lopau, K., Schnuelle, P., Nonnast-Daniel, B., Pietruck, F., Offermann, R., Persijn, G., & Bernasconi, C.
Venue
American Journal of Transplantation
Publisher
Elsevier BV
Published
2008-01
Volume
8
Issue
1
Pages
50-57
ISSN
1600-6135 (ISSN-L)
OpenAlex
W2093758449
Cited by
358
References
11
FWCI
8.46
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Prospective Age-Matching in Elderly Kidney Transplant Recipients—A 5-Year Analysis of the Eurotransplant Senior Program. https://app.cochat.ai/papers/10.1111/j.1600-6143.2007.02014.x
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Frei, U., Noeldeke, J., Machold-Fabrizii, V., Arbogast, H., Margreiter, R., Fricke, L., Voiculescu, A., Kliem, V., Ebel, H., Albert, U., Lopau, K., Schnuelle, P., Nonnast-Daniel, B., Pietruck, F., Offermann, R., Persijn, G., & Bernasconi, C. (2008). Prospective Age-Matching in Elderly Kidney Transplant Recipients—A 5-Year Analysis of the Eurotransplant Senior Program. American Journal of Transplantation. https://doi.org/10.1111/j.1600-6143.2007.02014.x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.