The DOI matches its Crossref record, with a small difference in title or year; 22 of the 24 references it cites were found in a registry or an index.
Prevalence of hypogonadism in males aged at least 45 years: the HIM study
Open accessAbstract
The Hypogonadism in Males study estimated the prevalence of hypogonadism [total testosterone (TT) < 300 ng/dl] in men aged > or = 45 years visiting primary care practices in the United States. A blood sample was obtained between 8 am and noon and assayed for TT, free testosterone (FT) and bioavailable testosterone (BAT). Common symptoms of hypogonadism, comorbid conditions, demographics and reason for visit were recorded. Of 2162 patients, 836 were hypogonadal, with 80 receiving testosterone. Crude prevalence rate of hypogonadism was 38.7%. Similar trends were observed for FT and BAT. Among men not receiving testosterone, 756 (36.3%) were hypogonadal; odds ratios for having hypogonadism were significantly higher in men with hypertension (1.84), hyperlipidaemia (1.47), diabetes (2.09), obesity (2.38), prostate disease (1.29) and asthma or chronic obstructive pulmonary disease (1.40) than in men without these conditions. The prevalence of hypogonadism was 38.7% in men aged > or = 45 years presenting to primary care offices.
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“Testosterone deficiency is highly prevalent, with rates increasing with age from 4% in men aged 40–49 years to nearly 50% in men over 80 years of age, with some studies suggesting a 17% increase in testosterone deficiency for every decade of life (2-4).”
From Non-testosterone management of male hypogonadism: an examination of the existing literature (2020) · cites this paper as [4]
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Cites
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Bhasin, S., Cunningham, G. R., Hayes, F. J., Matsumoto, A. M., Snyder, P. J., Swerdloff, R. S., & Montori, V. M. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2354 · Cited by 1,954
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Metadata
- Authors
- MULLIGAN, T., FRICK, M. F., ZURAW, Q. C., STEMHAGEN, A., & MCWHIRTER, C.
- Affiliations
- University of Florida (US)
- Covance (United States) (US)
- Solvay (United States) (US)
- Corresponding author
- MULLIGAN, T.
- ORCID
- MULLIGAN, T.
- Venue
- International Journal of Clinical Practice
- Publisher
- Hindawi Limited
- Published
- 2008-10-09
- Volume
- 60
- Issue
- 7
- Pages
- 762-769
- ISSN
- 1368-5031 (ISSN-L)
- PMC
- PMC1569444
- OpenAlex
- W1667402504
- Cited by
- 767
- References
- 24
- Citations by year
- 2026: 14 · 2025: 37 · 2024: 37 · 2023: 32 · 2022: 35 · 2021: 42 · 2020: 44 · 2019: 38 · 2018: 34 · 2017: 54 · 2016: 60 · 2015: 40 · 2014: 58 · 2013: 60 · 2012: 42
- FWCI
- 18.19
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- International Journal of Clinical Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Keywords
- hypogonadism, androgen deficiency, prevalence, primary care, free testosterone, bioavailable testosterone, comorbidities, hypertension, hyperlipidemia, diabetes mellitus, obesity, prostate diseases, asthma, chronic obstructive pulmonary disease, testosterone replacement therapy
- MeSH terms
- Aged, Aged, 80 and over, Humans, Hypogonadism, Male, Middle Aged, Testosterone, United States, Prevalence
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