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Thermoregulation during Work in Carbon Monoxide Poisoning

Nielsen, Bodil·1971·Acta Physiologica Scandinavica

Abstract

A mild to moderate CO poisoning, blocking 25 to 33 % of the oxygen binding capacity of the blood, was used to produce a change in maximal oxygen intake (max VO 2). Subjects working at the same work load (Vo 2= 1.5 1/min) for 1 hour under normal conditions and during CO poisoning showed an increase in plateau level of deep body temperature (T e8) of 0.3–0.5° C. The plateau levels correlated with the relative loads (percentage of max Vo 2) of the subjects but not with absolute work load and oxygen uptake. The CO‐poisoning may act 1) directly on the hypothalamic temperature center, the low tissue O 2 tensions changing the activity of its neurons, 2) through the low venous O 2 tensions on peripheral chemoreceptors in the working muscles or the venous side of the circulation, or 3) the changes in temperature may be a passive reaction to a shift in blood towards the periphery in the CO poisoned state.

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Crossref · 10.1111/j.1748-1716.1971.tb04946.x

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Citations

Cites

Research works printed but not linked: 37

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Metadata

Authors
Nielsen, B.
Venue
Acta Physiologica Scandinavica
Publisher
Wiley
Published
1971-05
Volume
82
Issue
1
Pages
98-106
ISSN
  • 0001-6772
  • 1365-201X
Cited by
18
References
1
Language
en

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