Manoeuvres affecting sympathetic outflow in human muscle nerves
Abstract
Abstract Multi‐unit sympathetic activity was recorded in human muscle nerves, together with measurements of intra‐arterial blood pressure and forearm or calf blood flow, during manoeuvres causing circulatory adjustments. Manoeuvres causing an increased vascular resistance in the forearm or calf were regularly associated with an increase in sympathetic outflow, proving that the neural activity was dominated by vasoconstrictor impulses. The inverse changes of blood pressure and sympathetic activity observed during Valsalva's manoeuvre and mental stress are explicable in terms of baroreflex control of the neural outflow. However, during muscle work and hyperventilation the relation between blood pressure and sympathetic activity was more complex, indicating that the baroreflex influence was superimposed or modified by other regulatory mechanisms. Some manoeuvres known to affect sympathetic outflow in skin nerves caused no appreciable change in sympathetic muscle nerve activity.
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The Valsalva-type manoeuvre is particularly potent in enhancing the sympathetic pulse synchronous outflow to the muscles.
“this type of manoeuvre is particularly potent in enhancing the sympathetic pulse synchronous outflow to the muscles.”
From Effects of the Jendrassik manoeuvre on muscle spindle activity in man. (1975) · cites this paper as Delius et al., 1972
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- Authors
- Delius, W., Hagbarth, K. ‐., Hongell, A., & Wallin, B. G.
- Affiliations
- Uppsala University Hospital (SE)
- Venue
- Acta Physiologica Scandinavica
- Publisher
- Wiley
- Published
- 1972-01
- Volume
- 84
- Issue
- 1
- Pages
- 82-94
- ISSN
- 0001-6772 (ISSN-L)
- 1365-201X
- OpenAlex
- W4237546140
- Cited by
- 316
- References
- 23
- Citations by year
- 2026: 3 · 2025: 8 · 2024: 9 · 2023: 6 · 2022: 2 · 2021: 4 · 2020: 8 · 2019: 8 · 2018: 7 · 2017: 11 · 2016: 6 · 2015: 8 · 2014: 6 · 2013: 5 · 2012: 10
- FWCI
- 7.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Physiologica Scandinavica (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Keywords
- sympathetic outflow, muscle nerves, baroreflex, Valsalva maneuver, psychological stress, hyperventilation, muscle work, vasoconstriction, vascular resistance, blood pressure, forearm blood flow, calf blood flow, skin nerves
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