GERMFREE ANIMALS AND LIVER NECROSIS
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The microbiota-TLR4 axis contributes importantly to liver fibrosis.
“There is strong evidence for an important contribution of the microbiota–TLR4 axis to liver fibrosis.”
From The gut microbiome and liver cancer: mechanisms and clinical translation (2017) · cites this paper as [71]
Antibiotics prevent hepatic injury and fibrosis induced by CCl4 treatment, bile duct ligation or a choline-deficient diet, and endotoxin enhances hepatic fibrosis induced by a choline-deficient diet.
“Studies from the past six decades have shown that antibiotics prevent hepatic injury and fibrosis induced by CCl4 treatment, bile duct ligation or a choline-deficient diet, and that endotoxin enhances hepatic fibrosis induced by a choline-deficient diet71–73.”
From The gut microbiome and liver cancer: mechanisms and clinical translation (2017) · cites this paper as [71]
Cites
THE NATURE OF THE BLEEDING IN JAUNDICE
Quick, A. J. (1938) · JAMA · doi:10.1001/jama.1938.02790200026009 · Cited by 252 · see citing works
Hove, E. L., Copeland, D. H., & Salmon, W. D. (1949) · Journal of Nutrition · doi:10.1093/jn/39.3.397 · Cited by 33 · see citing works
Reyniers, J. A., Trexler, P. C., Ervin, R. F., et al. (1950) · PubMed · doi:10.1093/jn/41.1.31 · Cited by 21 · see citing works
Self-citationFurther Observations on Yeast in Production of Experimental Hepatic Necrosis in Rats.
György, P., & Goldblatt, H. (1951) · Experimental Biology and Medicine · doi:10.3181/00379727-76-18409 · Cited by 5 · see citing works
Self-citation
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The gut microbiome and liver cancer: mechanisms and clinical translation
Yu, L.-X., & Schwabe, R. F. (2017) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2017.72 · Cited by 634 · see citing works
Small intestinal bacterial overgrowth in human cirrhosis is associated with systemic endotoxemia
Bauer, T. M., Schwacha, H., Steinbruckner, B., Brinkmann, F. E., Ditzen, A. K., Aponte, J. J., Pelz, K., Berger, D., Kist, M., & Blum, H. E. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.05791.x · Cited by 211 · see citing works
Toll-like Receptor 4 and Hepatic Fibrogenesis
Pradere, J.-P., Troeger, J., Dapito, D., Mencin, A., & Schwabe, R. (2010) · Seminars in Liver Disease · doi:10.1055/s-0030-1255353 · Cited by 158 · see citing works
THE ROLE OF INTESTINAL BACTERIA IN THE DEVELOPMENT OF DIETARY CIRRHOSIS IN RATS
Rutenburg, A. M., Sonnenblick, E., Koven, I., Aprahamian, H. A., Reiner, L., & Fine, J. (1957) · The Journal of Experimental Medicine · doi:10.1084/jem.106.1.1 · Cited by 108 · see citing works
- Authors
- Luckey, T. D., Reyniers, J. A., György, P., & Forbes, M.
- Affiliations
- University of Notre Dame (US)
- ORCID
- Forbes, M.
- Venue
- Annals of the New York Academy of Sciences
- Publisher
- Wiley
- Published
- 1954-05
- Volume
- 57
- Issue
- 6
- Pages
- 932-935
- ISSN
- 0077-8923 (ISSN-L)
- 1749-6632
- OpenAlex
- W2116350349
- Cited by
- 52
- References
- 4
- Citations by year
- 2026: 1 · 2023: 1 · 2018: 1 · 2017: 2 · 2015: 1 · 2014: 2 · 2012: 1
- FWCI
- 3.90
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of the New York Academy of Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Hepatology › Liver physiology and pathology
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Drug-Induced Hepatotoxicity and Protection
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- germ-free animals, liver necrosis, intestinal bacteria, bacterial translocation
- MeSH terms
- Animals, Liver Diseases, Necrosis, Life
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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