The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Fundamental Aspects of Reactive Oxygen Species, or What's the Matter with Oxygen?
Abstract
ABSTRACT: A byproduct of normal aerobic metabolism is the generation of dangerously reactive intermediates of the reduction of O 2. These include O 2−, H 2 O 2, and HO · and arise because of the predisposition of O 2 for univalent reductions. These reactive oxygen species (ROS), and others that they can engender, threaten all cellular macromolecules, and defenses are needed. Among those known to date are: superoxide dismutases to convert O 2− into O 2+ H 2 O 2; catalases to dismute H 2 O 2 into O 2+ H 2 O; and peroxidases to reduce H 2 O 2 into 2H 2 O) and to reduce ROOH into ROH and H 2 O. These defenses are aided by enzymes that repair or recycle oxidatively damaged nucleic acids and proteins. A role for such oxidative damage in aging and neurodegenerative diseases is well supported.
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Citations
Cites
Superoxide Anion Radical (O·̄2), Superoxide Dismutases, and Related Matters
Fridovich, I. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.30.18515 · Cited by 1,337
Self-citation
Cited by
Uttara, B., Singh, A., Zamboni, P., & Mahajan, R. (2009) · Current Neuropharmacology · doi:10.2174/157015909787602823 · Cited by 3,378
Oxidative stress and neurodegeneration: where are we now?
Halliwell, B. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03907.x · Cited by 2,614
Diabetes mellitus and oxidative stress—A concise review
Asmat, U., Abad, K., & Ismail, K. (2016) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2015.03.013 · Cited by 1,570
Trends in oxidative aging theories
Muller, F. L., Lustgarten, M. S., Jang, Y., Richardson, A., & Van Remmen, H. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.03.034 · Cited by 1,053
Complex iii releases superoxide to both sides of the inner mitochondrial membrane
Muller, F. L., Liu, Y., & Van Remmen, H. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407715200 · Cited by 1,036
Metadata
- Authors
- FRIDOVICH, I.
- Venue
- Annals of the New York Academy of Sciences
- Publisher
- Wiley
- Published
- 1999-11
- Volume
- 893
- Issue
- 1
- Pages
- 13-18
- ISSN
- 0077-8923 (ISSN-L)
- 1749-6632
- OpenAlex
- W2130004942
- Cited by
- 541
- References
- 1
- FWCI
- 4.46
- Type
- journal article
- Language
- en
- Open access
- closed
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- FRIDOVICH, I. (1999). Fundamental Aspects of Reactive Oxygen Species, or What's the Matter with Oxygen? Annals of the New York Academy of Sciences. https://doi.org/10.1111/j.1749-6632.1999.tb07814.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
