The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.
Scavenger receptor class B type I: a multifunctional receptor
Open accessAbstract
The scavenger receptor class B type I (SR‐B1) plays an important role in meditating the uptake of HDL‐derived cholesterol and cholesteryl ester in the liver and steroidogenic tissues. In addition to being ubiquitous, SR‐B1 is a high‐density lipoprotein (HDL) receptor in many tissues, though the mechanism by which SR‐B1 does this is unclear. Other than its role as an HDL receptor, SR‐B1 is also involved in pathogen recognition; its expression can be modulated by lipopolysaccharide and oxidative stress; and it plays a significant role in the uptake of lipid soluble vitamins, such as vitamin E and carotenoids. In this short review, we have summarized the biological aspects to which SR‐B1 has been thus far associated.
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“Additionally, SCARB1 can also serve as a transporter for vitamins, including tocopherols, and carotenoids such as β-carotene and xanthophylls [10,11].”
From Vitamin A Transporters in Visual Function: A Mini Review on Membrane Receptors for Dietary Vitamin A Uptake, Storage, and Transport to the Eye (2021) · cites this paper as [10]
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Identification of Scavenger Receptor SR-BI as a High Density Lipoprotein Receptor
Acton, S., Rigotti, A., Landschulz, K. T., Xu, S., Hobbs, H. H., & Krieger, M. (1996) · Science · doi:10.1126/science.271.5248.518 · Cited by 2,026
Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System
Goldstein, J. L., Brown, M. S., Anderson, R. G. W., Russell, D. W., & Schneider, W. J. (1985) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.01.110185.000245 · Cited by 1,600
Data Sharing by Scientists: Practices and Perceptions
Tenopir, C., Allard, S., Douglass, K., Aydinoglu, A. U., Wu, L., Read, E., Manoff, M., & Frame, M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021101 · Cited by 1,432
Rigotti, A., Trigatti, B. L., Penman, M., Rayburn, H., Herz, J., & Krieger, M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.23.12610 · Cited by 860
Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels
Kozarsky, K., Donahee, M. H., Rigotti, A., Iqbal, S. N., Edelman, E. R., & Krieger, M. (1997) · Nature · doi:10.1038/387414a0 · Cited by 697
High Density Lipoproteins and Arteriosclerosis
von Eckardstein, A., Nofer, J., & Assmann, G. (2001) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.21.1.13 · Cited by 696
Scavenger Receptor BI Promotes High Density Lipoprotein-mediated Cellular Cholesterol Efflux
Ji, Y. I., Jian, B., Wang, N., Sun, Y., Moya, M. D. L. L., Phillips, M. C., Rothblat, G. H., Swaney, J. B., & Tall, A. R. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.34.20982 · Cited by 694
Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo
Wang, X., Collins, H. L., Ranalletta, M., Fuki, I. V., Billheimer, J. T., Rothblat, G. H., Tall, A. R., & Rader, D. J. (2007) · Journal of Clinical Investigation · doi:10.1172/jci32057 · Cited by 593
Krieger, M. (1999) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.68.1.523 · Cited by 517
Rahman, I., & MacNee, W. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00215-x · Cited by 484
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Dyslipidemia in the Pediatric Population
Sunil, B., & Ashraf, A. P. (2020) · Springer eBooks · doi:10.1007/978-3-030-52215-5_57
Denton, N. (2021) · Oxford University Press eBooks · doi:10.1093/med/9780198865278.003.0003
Rani, M. R., Azemi, A. K., Bakar, K., Abu-Bakar, L., Muhammad, T. S. T., & Ismail, N. (2024) · Natural Product Research · doi:10.1080/14786419.2024.2327851
Delgado, S. E. (2017) · theses.fr (ABES) · doi:10.70675/d8aabbbazd750z4f3cz824czd7ae7217f99a
Ming, R., Gao, X., Hu, X., Yang, Z., Liang, C., Zhang, G., Luo, B., Cheng, S., & Li, Y. (2026) · ACS Sensors · doi:10.1021/acssensors.6c01215
Metadata
- Authors
- Valacchi, G., Sticozzi, C., Lim, Y., & Pecorelli, A.
- Affiliations
- University of Ferrara (IT)
- University of Trento (IT)
- Kyung Hee University (KR)
- University of Siena (IT)
- Corresponding author
- Valacchi, Giuseppe
- Venue
- Annals of the New York Academy of Sciences
- Publisher
- Wiley
- Published
- 2011-07
- Volume
- 1229
- Issue
- 1
- Pages
- E1-7
- ISSN
- 0077-8923 (ISSN-L)
- 1749-6632
- OpenAlex
- W1671549322
- Semantic Scholar
- 8d8aa42c23deabac7c734ebce862fbf1ccf9108b
- Cited by
- 108
- References
- 82
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 3 · 2023: 4 · 2022: 4 · 2021: 8 · 2020: 8 · 2019: 9 · 2018: 6 · 2017: 15 · 2016: 6 · 2015: 13 · 2014: 15 · 2013: 6 · 2012: 6
- FWCI
- 1.56
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Annals of the New York Academy of Sciences (publishedVersion)
- PubMed (publishedVersion)
- Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion)
- Funders
- Ministero dell’Istruzione, dell’Università e della Ricerca
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Oncology › Drug Transport and Resistance Mechanisms
- Keywords
- scavenger receptor class B type I, HDL cholesterol uptake, cholesterol esters, liver, steroidogenic tissues, HDL receptor, pathogen recognition, lipopolysaccharide, oxidative stress, carotenoid uptake, fat-soluble vitamins
- MeSH terms
- Adrenal Cortex, Animals, Biological Transport, Carotenoids, Cholesterol Esters, Humans, Lipopolysaccharides, Cholesterol, HDL, Liver, Lung, Membrane Proteins, Tissue Distribution, Vitamin E, Mice, Knockout, Oxidative Stress, CD36 Antigens, Mice, Rats, Hep G2 Cells
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