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Progressive Supranuclear Palsy: Pathology and Genetics
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Progressive supranuclear palsy (PSP) is an atypical Parkinsonian disorder associated with progressive axial rigidity, vertical gaze palsy, dysarthria and dysphagia. Neuropathologically, the subthalamic nucleus and brainstem, especially the midbrain tectum and the superior cerebellar peduncle, show atrophy. The substantia nigra shows loss of pigment corresponding to nigrostriatal dopaminergic degeneration. Microscopic findings include neuronal loss, gliosis and neurofibrillary tangles in basal ganglia, diencephalon and brainstem. Characteristic tau pathology is also found in glia. The major genetic risk factor for sporadic PSP is a common variant in the gene encoding microtubule‐associated protein tau (MAPT) and recent studies have suggested that this may result in the altered expression of specific tau protein isoforms. Imaging studies suggest that there may be sensitive and specific means to differentiate PSP from other parkinsonian disorders, but identification of a diagnostic biomarker is still elusive.
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“Progressive supranuclear palsy (PSP) is a devastating neurodegenerative disorder caused by the neuro-glial aggregation of tau protein, particularly in the basal ganglia, diencephalon, and brainstem1,2.”
From Neuroinflammation and Tau Colocalize in vivo in Progressive Supranuclear Palsy (2020) · cites this paper as [1]
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Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
Hutton, M., Lendon, C. L., Rizzu, P., Baker, M., Froelich, S., Houlden, H., Pickering-Brown, S., Chakraverty, S., Isaacs, A., Grover, A., et al. (1998) · Nature · doi:10.1038/31508 · Cited by 3,498
Self-citationMutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology
Zimprich, A. A., Biskup, S., Leitner, P., Lichtner, P., Farrer, M. J., Lincoln, S., Kachergus, J. M., Hulihan, M., Uitti, R. J., Calne, D. B., et al. (2004) · Neuron · doi:10.1016/j.neuron.2004.11.005 · Cited by 3,087
Self-citationGoedert, M., Spillantini, M. G., Jakes, R., Rutherford, D., & Crowther, R. A. (1989) · Neuron · doi:10.1016/0896-6273(89)90210-9 · Cited by 2,492
Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's Disease
Paisán‐Ruiz, C., Jain, S., Evans, E. W., Gilks, W. P., Simón, J., van der Brug, M., de Munaín, A. L., Aparicio, S. F., Gil, A. M., Khan, N. L., et al. (2004) · Neuron · doi:10.1016/j.neuron.2004.10.023 · Cited by 2,453
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17
Baker, M., Mackenzie, I. R., Pickering-Brown, S. M., Gass, J., Rademakers, R., Lindholm, C., Snowden, J., Adamson, J., Sadovnick, A. D., Rollinson, S., et al. (2006) · Nature · doi:10.1038/nature05016 · Cited by 2,058
Self-citationProgressive Supranuclear Palsy
Steele, J. C. (1964) · Archives of Neurology · doi:10.1001/archneur.1964.00460160003001 · Cited by 1,930
Cruts, M., Gijselinck, I., van der Zee, J., Engelborghs, S., Wils, H., Pirici, D., Rademakers, R., Vandenberghe, R., Dermaut, B., Martin, J.-J., et al. (2006) · Nature · doi:10.1038/nature05017 · Cited by 1,512
Self-citationMutation in the tau gene in familial multiple system tauopathy with presenile dementia
Spillantini, M. G., Murrell, J. R., Goedert, M., Farlow, M. R., Klug, A., & Ghetti, B. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.13.7737 · Cited by 1,474
Tau is a candidate gene for chromosome 17 frontotemporal dementia
Poorkaj, P., Bird, T. D., Wijsman, E., Nemens, E., Garruto, R. M., Anderson, L., Andreadis, A., Wiederholt, W. C., Raskind, M., & Schellenberg, G. D. (1998) · Annals of Neurology · doi:10.1002/ana.410430617 · Cited by 1,374
A common inversion under selection in Europeans
Stefánsson, H., Helgason, A., Þorleifsson, G., Steinthórsdóttir, V., Másson, G., Barnard, J., Baker, A., Jónasdóttir, Á., Ingason, A., Gudnadottir, V. G., et al. (2005) · Nature Genetics · doi:10.1038/ng1508 · Cited by 847
Association of an Extended Haplotype in the Tau Gene with Progressive Supranuclear Palsy
Baker, M., Litvan, I., Houlden, H., Adamson, J., Dickson, D., Perez-Tur, J., Hardy, J., Lynch, T., Bigio, E., & Hutton, M. (1999) · Human Molecular Genetics · doi:10.1093/hmg/8.4.711 · Cited by 781
Self-citationWilliams, D. R., de Silva, R., Paviour, D. C., Pittman, A. M., Watt, H., Kilford, L., Holton, J. L., Révész, T., & Lees, A. J. (2005) · Brain · doi:10.1093/brain/awh488 · Cited by 747
Office of Rare Diseases Neuropathologic Criteria for Corticobasal Degeneration
Dickson, D. W., Bergeron, C., Chin, S. S., Duyckaerts, C., Horoupian, D., Ikeda, K., Jellinger, K., Lantos, P. L., Lippa, C. F., Mirra, S. S., et al. (2002) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/61.11.935 · Cited by 724
Self-citationStructure and novel exons of the human .tau. gene
Andreadis, A., Brown, W. M., & Kosik, K. S. (1992) · Biochemistry · doi:10.1021/bi00158a027 · Cited by 659
Corticodentatonigral Degeneration With Neuronal Achromasia
Rebeiz, J. J., Kolodny, E. H., & Richardson, E. P. (1968) · Archives of Neurology · doi:10.1001/archneur.1968.00470310034003 · Cited by 627
Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration
Gass, J. M., Cannon, A. D., Mackenzie, I. R., Boeve, B. F., Baker, M. C., Adamson, J. L., Crook, R., Melquist, S., Kuntz, K., Petersen, R. C., et al. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddl241 · Cited by 587
Self-citationFrontotemporal Dementia and Corticobasal Degeneration in a Family with a P301S Mutation in Tau
Bugiani, O., Murrell, J. R., Giaccone, G., Hasegawa, M., Ghigo, G., Tabaton, M., Morbin, M., Primavera, A., Carella, F., Solaro, C., et al. (1999) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199906000-00011 · Cited by 450
Neuropathologic differentiation of progressive supranuclear palsy and corticobasal degeneration
Dickson, D. W. (1999) · Journal of Neurology · doi:10.1007/bf03161076 · Cited by 424
Self-citationGenetic evidence for the involvement of τ in progressive supranuclear palsy
Conrad, C., Andreadis, A., Trojanowski, J. Q., Dickson, D. W., Kang, D. E., Chen, X., Wiederholt, W. C., Hansen, L., Masliah, E., Thal, L. J., et al. (1997) · Annals of Neurology · doi:10.1002/ana.410410222 · Cited by 388
Self-citationNew and reliable MRI diagnosis for progressive supranuclear palsy
Oba, H., YAGISHITA, A., Terada, H., Barkovich, A. J., Kutomi, K., Yamauchi, T., Furui, S., Shimizu, T., Uchigata, M., Matsumura, K., et al. (2005) · Neurology · doi:10.1212/01.wnl.0000165960.04422.d0 · Cited by 377
Buée, L., & Delacourte, A. (1999) · Brain Pathology · doi:10.1111/j.1750-3639.1999.tb00550.x · Cited by 368
The role of tau (MAPT) in frontotemporal dementia and related tauopathies
Rademakers, R., Cruts, M., & Broeckhoven, C. V. (2004) · Human Mutation · doi:10.1002/humu.20086 · Cited by 361
Self-citationPittman, A. M., Myers, A. J., Abou‐Sleiman, P. M., Fung, H., Kaleem, M., Marlowe, L., Duckworth, J., Leung, D. G., Williams, D. R., Kilford, L., et al. (2005) · Journal of Medical Genetics · doi:10.1136/jmg.2005.031377 · Cited by 283
Self-citationKomori, T. (1999) · Brain Pathology · doi:10.1111/j.1750-3639.1999.tb00549.x · Cited by 282
Panda, D., Samuel, J. C., Massie, M., Feinstein, S. C., & Wilson, L. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1633508100 · Cited by 280
Braak, H., & Braak, E. (1989) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1989.tb01146.x · Cited by 276
Widespread cytoskeletal pathology characterizes corticobasal degeneration.
Feany, M. Β., & Dickson, D. W. (1995) · PubMed Central · Cited by 275
Self-citationArgyrophilic Grain Disease Is a Sporadic 4-Repeat Tauopathy
Togo, T., Sahara, N., Yen, S.-H., Cookson, N., Ishizawa, T., Hutton, M., de Silva, R., Lees, A., & Dickson, D. W. (2002) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/61.6.547 · Cited by 273
Self-citationAutosomal dominant parkinsonism associated with variable synuclein and tau pathology
Wszolek, Z. K., Pfeiffer, R. F., Tsuboi, Y., Uitti, R. J., McComb, R. D., Stoessl, A. J., Strongosky, A. J., Zimprich, A. A., Müller‐Myhsok, B., Farrer, M. J., et al. (2004) · Neurology · doi:10.1212/01.wnl.0000125015.06989.db · Cited by 266
Self-citationFeany, M. Β., Mattiace, L. A., & Dickson, D. W. (1996) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199601000-00006 · Cited by 264
Self-citationMyers, A., Pittman, A. M., Zhao, A. S., Rohrer, K., Kaleem, M. A., Marlowe, L., Lees, A. J., Leung, D. G., McKeith, I. G., Perry, R. H., et al. (2006) · Neurobiology of Disease · doi:10.1016/j.nbd.2006.10.018 · Cited by 263
Stanford, P. M., Halliday, G. M., Brooks, W. S., Kwok, J. B. J., Storey, C. E., Creasey, H., Morris, J. G. L., Fulham, M. J., & Schofield, P. R. (2000) · Brain · doi:10.1093/brain/123.5.880 · Cited by 262
Paviour, D. C., Price, S. L., Jahanshahi, M., Lees, A. J., & Fox, N. C. (2006) · Brain · doi:10.1093/brain/awl021 · Cited by 217
Hauw, J., Verny, M., Delaère, P., Cervera, P., He, Y., & Duyckaerts, C. J. (1990) · Neuroscience Letters · doi:10.1016/0304-3940(90)90829-x · Cited by 216
Parkinsonism, Lrrk2 G2019S, and tau neuropathology
Rajput, A. H., Dickson, D. W., Robinson, C. A., Ross, O. A., Dächsel, J. C., Lincoln, S. J., Cobb, S. A., Rajput, M. L., & Farrer, M. J. (2006) · Neurology · doi:10.1212/01.wnl.0000240220.33950.0c · Cited by 210
Self-citationIshizawa, K., & Dickson, D. W. (2001) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/60.6.647 · Cited by 209
Self-citationAn R5L τ mutation in a subject with a progressive supranuclear palsy phenotype
Poorkaj, P., Muma, N. A., Zhukareva, V. A., Cochran, E. J., Shannon, K. M., Hurtig, H. I., Koller, W. C., Bird, T. D., Trojanowski, J. Q., Lee, V. M. ‐., et al. (2002) · Annals of Neurology · doi:10.1002/ana.10340 · Cited by 203
Josephs, K. A., Boeve, B. F., Duffy, J. R., Smith, G. E., Knopman, D. S., Parisi, J. E., Petersen, R. C., & Dickson, D. W. (2005) · Neurocase · doi:10.1080/13554790590963004 · Cited by 196
Self-citationUltrastructure of Neurofibrillary Tangles in Steele-Richardson-Olszewski Syndrome
Tellez-Nagel, I., & Wı́sniewski, H. M. (1973) · Archives of Neurology · doi:10.1001/archneur.1973.00490290064007 · Cited by 185
Josephs, K. A., Ahmed, Z., Katsuse, O., Parisi, J. F., Boeve, B. F., Knopman, D. S., Petersen, R. C., Davies, P., Duara, R., Graff‐Radford, N. R., et al. (2007) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e31803020cf · Cited by 184
Self-citationQuantitative MRI measurement of superior cerebellar peduncle in progressive supranuclear palsy
Paviour, D. C., Price, S. L., Stevens, J., Lees, A. J., & Fox, N. C. (2005) · Neurology · doi:10.1212/01.wnl.0000151854.85743.c7 · Cited by 173
Delisle, M., Murrell, J. R., Richardson, R., Trofatter, J. A., Rascol, O., Soulages, X., Mohr, M., Calvas, P., & Ghetti, B. F. (1999) · Acta Neuropathologica · doi:10.1007/s004010051052 · Cited by 171
Komori, T., Arai, N., Oda, M., Nakayama, H., Mori, H., Yagishita, S., Takahashi, T., Amano, N., Murayama, S., Murakami, S., et al. (1998) · Acta Neuropathologica · doi:10.1007/s004010050911 · Cited by 166
Josephs, K. A., & Dickson, D. W. (2003) · Movement Disorders · doi:10.1002/mds.10488 · Cited by 164
Self-citationRademakers, R., Melquist, S., Cruts, M., Theuns, J., Del-Favero, J., Poorkaj, P., Baker, M., Sleegers, K., Crook, R., De Pooter, T., et al. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi361 · Cited by 164
Self-citationCerebrospinal fluid tau levels in neurodegenerative diseases with distinct tau-related pathology
Arai, H., Morikawa, Y.-I., Higuchi, M., Matsui, T., Clark, C. M., Miura, M., Machida, N., Lee, V. M.-Y., Trojanowski, J. Q., & Sasaki, H. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.6908 · Cited by 159
Atypical Progressive Supranuclear Palsy With Corticospinal Tract Degeneration
Josephs, K. A., Katsuse, O., Beccano-Kelly, D. A., Lin, W.-L., Uitti, R. J., Fujino, Y., Boeve, B. F., Hutton, M. L., Baker, M., & Dickson, D. W. (2006) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/01.jnen.0000218446.38158.61 · Cited by 152
Self-citationBallooned neurons in select neurodegenerative diseases contain phosphorylated neurofilament epitopes
Dickson, D. W., Yen, S. H., Suzuki, K., Davies, P., García, J. H., & Hirano, A. (1986) · Acta Neuropathologica · doi:10.1007/bf00688042 · Cited by 146
Self-citationHaplotype-specific expression of exon 10 at the human MAPT locus
Caffrey, T. M., Joachim, C. L., Paracchini, S., Esiri, M. M., & Wade‐Martins, R. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddl429 · Cited by 135
Tsuboi, Y., Josephs, K. A., Boeve, B. F., Litvan, I., Caselli, R. J., Caviness, J. N., Uitti, R. J., Bott, A. D., & Dickson, D. W. (2005) · Movement Disorders · doi:10.1002/mds.20478 · Cited by 131
Self-citationAtrophy of superior cerebellar peduncle in progressive supranuclear palsy
Tsuboi, Y., Slowinski, J. L., Josephs, K. A., Honer, W. G., Wszołek, Z. K., & Dickson, D. W. (2003) · Neurology · doi:10.1212/01.wnl.0000068011.21396.f4 · Cited by 130
Self-citationNishimura, M., Namba, Y., Ikeda, K., & Oda, M. (1992) · Neuroscience Letters · doi:10.1016/0304-3940(92)90227-x · Cited by 124
The tau H2 haplotype is almost exclusively Caucasian in origin
Evans, E. W., Fung, H., Steele, J. C., Eerola, J., Tienari, P. J., Pittman, A. M., de Silva, R., Myers, A., Vrièze, F. W., Singleton, A., et al. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.05.119 · Cited by 117
Clinical genetics of familial progressive supranuclear palsy
Rojo, A., Pernaute, R. S., Fontán, A., Ruiz, P., Honnorat, J., Lynch, T., Chin, S. S., Gonzalo, I., Rábano, A., Martínez, A., et al. (1999) · Brain · doi:10.1093/brain/122.7.1233 · Cited by 115
Morris, H. R., Janssen, J. C., Bandmann, O., Daniel, S. E., Rossor, M. N., Lees, A. J., & Wood, N. W. (1999) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.66.5.665 · Cited by 107
Bergeron, C., Davis, A. M., & Lang, A. E. (1998) · Brain Pathology · doi:10.1111/j.1750-3639.1998.tb00159.x · Cited by 103
Togo, T., Cookson, N., & Dickson, D. W. (2002) · Brain Pathology · doi:10.1111/j.1750-3639.2002.tb00421.x · Cited by 100
Self-citationUrakami, K., Wada, K., Arai, H., Sasaki, H., Kanai, M., Shoji, M., Ishizu, H., Kashihara, K., Yamamoto, M., Tsuchiya-Ikemoto, K., et al. (2001) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(00)00480-9 · Cited by 97
A New Mutation of the τ Gene, G303V, in Early-Onset Familial Progressive Supranuclear Palsy
Ros, R., Thobois, S., Streichenberger, N., Kopp, N., Sánchez, M. P., Pérez, M., Hoenicka, J., Ávila, J., Honnorat, J., & de Yébenes, J. G. (2005) · Archives of Neurology · doi:10.1001/archneur.62.9.1444 · Cited by 93
Cholinergic systems in progressive supranuclear palsy
Warren, N. (2004) · Brain · doi:10.1093/brain/awh391 · Cited by 91
Tau exon 10 +16 mutation FTDP-17 presenting clinically as sporadic young onset PSP
Morris, H. R., Osaki, Y., Holton, J. L., Lees, A. J., Wood, N. W., Révész, T., & Quinn, N. P. (2003) · Neurology · doi:10.1212/01.wnl.0000072325.27824.a5 · Cited by 91
Higgins, J. J., Litvan, I., Pho, L. T., Li, W., & Nee, L. E. (1998) · Neurology · doi:10.1212/wnl.50.1.270 · Cited by 89
Familial progressive supranuclear palsy
de Yébenes, J. G., Sarasa, J. L., Daniel, S. E., & Lees, A. J. (1995) · Brain · doi:10.1093/brain/118.5.1095 · Cited by 89
Cruts, M., Rademakers, R., Gijselinck, I., van der Zee, J., Dermaut, B., Pooter, T. D., Rijk, P. D., Del‐Favero, J., & Broeckhoven, C. V. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi182 · Cited by 87
Self-citationProgressive Supranuclear Palsy with Dementia: Cortical Pathology
Bigio, E. H., Brown, D. F., & White, C. L. (1999) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199904000-00006 · Cited by 85
Direct genetic evidence for involvement of tau in progressive supranuclear palsy
Bennett, P., Bonifati, V., Bonuccelli, U., Colosimo, C., Mari, M. D., Fabbrini, G., Marconi, R., Meco, G., Nicholl, D. J., Stocchi, F., et al. (1998) · Neurology · doi:10.1212/wnl.51.4.982 · Cited by 85
The basal nucleus of Meynert in patients with progressive supranuclear palsy
Tagliavini, F., Pilleri, G., Bouras, C., & Constantinidis, J. (1984) · Neuroscience Letters · doi:10.1016/0304-3940(84)90217-9 · Cited by 82
Kato, S., Hirano, A., Umahara, T., KATO, M., Herz, F., & Ohama, E. (1992) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1992.tb00795.x · Cited by 75
Noguchi, M., Yoshita, M., Matsumoto, Y., Ono, K., Iwasa, K., & Yamada, M. (2005) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2005.05.015 · Cited by 73
Togo, T., & Dickson, D. W. (2002) · Acta Neuropathologica · doi:10.1007/s00401-002-0520-1 · Cited by 72
Self-citationDickson, D. W., Kress, Y., Crowe, A., & Yen, S. H. (1985) · PubMed Central · Cited by 71
Self-citationOliva, R., TOLOSA, E. S., Ezquerra, M., Molinuevo, J. L., Valldeoriola, F., Burguera, J. A., Calopa, M., Villa, M., & Ballesta, F. (1998) · Archives of Neurology · doi:10.1001/archneur.55.8.1122 · Cited by 69
Liu, W.-K., Le, T. V., Adamson, J. L., Baker, M., Cookson, N., Hardy, J., Hutton, M. L., Yen, S.-H. C., & Dickson, D. W. (2001) · Annals of Neurology · doi:10.1002/ana.1159 · Cited by 69
Self-citationLewy Bodies in Progressive Supranuclear Palsy Represent an Independent Disease Process
Uchikado, H., DelleDonne, A., Ahmed, Z., & Dickson, D. W. (2006) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/01.jnen.0000218449.17073.43 · Cited by 65
Self-citationUpdate on epidemiological aspects of progressive supranuclear palsy
Litvan, I. (2003) · Movement Disorders · doi:10.1002/mds.10562 · Cited by 64
Arima, K., Nakamura, M., Sunohara, N., Ogawa, M., Anno, M., Izumiyama, Y., Hirai, S., & Ikeda, K. (1997) · Acta Neuropathologica · doi:10.1007/s004010050652 · Cited by 59
Tolnay, M., & Probst, A. (1998) · Neuroscience Letters · doi:10.1016/s0304-3940(98)00250-x · Cited by 54
A Qualitative and Quantitative Study of Grumose Degeneration in Progressive Supranuclear Palsy
Ishizawa, K., Lin, W.-L., Tiseo, P. J., Honer, W. G., Davies, P. J., & Dickson, D. W. (2000) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/59.6.513 · Cited by 52
Self-citationConrad, C., Amano, N., Andreadis, A., Xia, Y., Namekataf, K., Oyama, F., Ikeda, K., Wakabayashi, K., Takahashi, H., Thal, L. J., et al. (1998) · Neuroscience Letters · doi:10.1016/s0304-3940(98)00417-0 · Cited by 50
Genetic linkage of autosomal dominant progressive supranuclear palsy to 1q31.1
Ros, R., Gómez‐Garre, P., Hirano, M., Tai, Y., Ampuero, I., Vidal, L., Rojo, A., Fontán, A., Vazquez, A., Fanjul, S., et al. (2005) · Annals of Neurology · doi:10.1002/ana.20449 · Cited by 49
Lewy bodies are not increased in progressive supranuclear palsy compared with normal controls
Tsuboi, Y., Ahlskog, J. E., Apaydın, H., Parisi, J. E., & Dickson, D. W. (2001) · Neurology · doi:10.1212/wnl.57.9.1675 · Cited by 48
Self-citationAstrocytic pathology in progressive supranuclear palsy: significance for neuropathological diagnosis
Matsusaka, H., Ikeda, K., Akiyama, H., Arai, T., Inoue, M., & Yagishita, S. (1998) · Acta Neuropathologica · doi:10.1007/s004010050891 · Cited by 45
Presymptomatic Hypertension Is a Major Feature in the Diagnosis of Progressive Supranuclear Palsy
Ghika, J., & Bogousslavsky, J. (1997) · Archives of Neurology · doi:10.1001/archneur.1997.00550210038010 · Cited by 45
APOE E4 is a determinant for Alzheimer type pathology in progressive supranuclear palsy
Tsuboi, Y., Josephs, K. A., Cookson, N., & Dickson, D. W. (2003) · Neurology · doi:10.1212/01.wnl.0000044340.37138.a9 · Cited by 45
Self-citationLrrk2 R1441 substitution and progressive supranuclear palsy
Ross, O. A., Whittle, A. J., Cobb, S. A., Hulihan, M., Lincoln, S. J., Toft, M., Farrer, M. J., & Dickson, D. W. (2006) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2006.00693.x · Cited by 40
Self-citationProgressive supranuclear palsy presenting with pure akinesia.
Mizusawa, H., Mochizuki, A., Ohkoshi, N., Yoshizawa, K., Kanazawa, I., & Imai, H. (1993) · PubMed · Cited by 39
Spinal cord lesions in progressive supranuclear palsy: some new observations
Kato, T., Hirano, A., Weinberg, M. N., & Jacobs, A. K. (1986) · Acta Neuropathologica · doi:10.1007/bf00687955 · Cited by 37
Mental Rotation of Perspective Stimuli in a California Sea Lion (Zalophus californianus)
Stich, K. P., Dehnhardt, G., & Mauck, B. (2003) · Brain Behavior and Evolution · doi:10.1159/000069355 · Cited by 36
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Metadata
- Authors
- Dickson, D. W., Rademakers, R., & Hutton, M. L.
- Affiliations
- Mayo Clinic in Florida (US)
- Venue
- Brain Pathology
- Publisher
- Wiley
- Published
- 2007-01
- Volume
- 17
- Issue
- 1
- Pages
- 74-82
- ISSN
- 1015-6305 (ISSN-L)
- 1750-3639
- PMC
- PMC8095545
- OpenAlex
- W2014875179
- Cited by
- 314
- References
- 99
- Citations by year
- 2026: 20 · 2025: 24 · 2024: 25 · 2023: 25 · 2022: 15 · 2021: 17 · 2020: 11 · 2019: 18 · 2018: 7 · 2017: 25 · 2016: 19 · 2015: 11 · 2014: 17 · 2013: 14 · 2012: 10
- FWCI
- 1.58
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Brain Pathology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (R01AG015866, P01AG014449, P01AG003949, P50AG025711, P01AG017216, P50AG016574)
- National Institute of Neurological Disorders and Stroke (P01NS040256, P50NS040256)
- National Institute of Environmental Health Sciences (R01ES013941, R01-ES02941)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Keywords
- progressive supranuclear palsy, tauopathy, tau pathology, MAPT gene, tau isoforms, atypical parkinsonism, subthalamic nucleus, midbrain tectum, superior cerebellar peduncle, nigrostriatal degeneration, neurofibrillary tangles, gliosis, brainstem atrophy, differential diagnosis, diagnostic biomarkers, neuroimaging
- MeSH terms
- Humans, Supranuclear Palsy, Progressive, tau Proteins
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