The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Polyunsaturated Fatty Acid Regulation of Gene Expression
Open accessAbstract
Polyunsaturated fatty acids (PUFAs), specifically the n-3 series, have been implicated in the prevention of various human diseases, including obesity, diabetes, coronary heart disease and stroke, and inflammatory and neurologic diseases. PUFAs function mainly by altering membrane lipid composition, cellular metabolism, signal transduction, and regulation of gene expression. PUFAs regulate the expression of genes in various tissues, including the liver, heart, adipose tissue, and brain. The role of transcription factors such as SREBP1c and nuclear receptors such as PPAR-alpha, HNF-4alpha, and LXRalpha in mediating the nuclear effects of PUFAs are addressed.
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Cites
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Unsaturated Fatty Acids Down-regulate SREBP Isoforms 1a and 1c by Two Mechanisms in HEK-293 Cells
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Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression
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Cited by
Triglycerides and Cardiovascular Disease: A Scientific Statement From the American Heart Association
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POLYUNSATURATED FATTY ACID REGULATION OF GENES OF LIPID METABOLISM
Sampath, H., & Ntambi, J. M. (2005) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.25.051804.101917 · Cited by 555
Self-citationOmega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives
Harris, W. S., Miller, M., Tighe, A. P., Davidson, M. H., & Schaefer, E. J. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2007.11.008 · Cited by 552
Anticonvulsant Mechanisms of the Ketogenic Diet
Bough, K. J., & Rho, J. M. (2007) · Epilepsia · doi:10.1111/j.1528-1167.2007.00915.x · Cited by 523
REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis
Le Martelot, G., Claudel, T., Gatfield, D., Schaad, O., Kornmann, B., Sasso, G. L., Moschetta, A., & Schibler, U. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000181 · Cited by 447
Metadata
- Authors
- Sampath, H., & Ntambi, J. M.
- Venue
- Nutrition Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-09
- Volume
- 62
- Issue
- 9
- Pages
- 333-339
- ISSN
- 0029-6643 (ISSN-L)
- 1753-4887
- OpenAlex
- W2063270248
- Cited by
- 239
- References
- 8
- FWCI
- 13.54
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
