The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Assessment of iodine nutrition in populations: past, present, and future
Open accessAbstract
Iodine status has been historically assessed by palpation of the thyroid and reported as goiter rates. Goiter is a functional biomarker that can be applied to both individuals and populations, but it is subjective. Iodine status is now assessed using an objective biomarker of exposure, i.e., urinary iodine concentrations (UICs) in spot samples and comparison of the median UIC to UIC cut-offs to categorize population status. This has improved standardization, but inappropriate use of the crude proportion of UICs below the cut-off level of 100 µg/L to estimate the number of iodine-deficient children has led to an overestimation of the prevalence of iodine deficiency. In this review, a new approach is proposed in which UIC data are extrapolated to iodine intakes, adjusted for intraindividual variation, and then interpreted using the estimated average requirement cut-point model. This may allow national programs to define the prevalence of iodine deficiency in the population and to quantify the necessary increase in iodine intakes to ensure sufficiency. In addition, thyroglobulin can be measured on dried blood spots to provide an additional sensitive functional biomarker of iodine status.
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Cites
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Andersson, M., Karumbunathan, V., & Zimmermann, M. B. (2012) · The Journal of Nutrition · doi:10.3945/jn.111.149393 · Cited by 703
Self-citationRelative contributions of dietary sodium sources
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Iodine intake as a determinant of thyroid disorders in populations
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Iodine-Induced Hyperthyroidism: Occurrence and Epidemiology
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Cited by
Maternal and child undernutrition and overweight in low-income and middle-income countries
Black, R. E., Victora, C. G., Walker, S. P., Bhutta, Z. A., Christian, P., de Onis, M., Ezzati, M., Grantham-McGregor, S., Katz, J., Martorell, R., et al. (2013) · The Lancet · doi:10.1016/s0140-6736(13)60937-x · Cited by 8,475
Iodine deficiency and thyroid disorders
Zimmermann, M. B., & Boelaert, K. (2015) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(14)70225-6 · Cited by 930
Self-citationGlobal Iodine Nutrition: Where Do We Stand in 2013?
Pearce, E. N., Andersson, M., & Zimmermann, M. B. (2013) · Thyroid · doi:10.1089/thy.2013.0128 · Cited by 438
Self-citationHynes, K. L., Otahal, P., Hay, I., & Burgess, J. R. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-4249 · Cited by 296
Biomarkers of Nutrition for Development—Iodine Review
Rohner, F., Zimmermann, M., Jooste, P., Pandav, C., Caldwell, K., Raghavan, R., & Raiten, D. J. (2014) · The Journal of Nutrition · doi:10.3945/jn.113.181974 · Cited by 281
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Metadata
- Authors
- Zimmermann, M. B., & Andersson, M.
- Venue
- Nutrition Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-10
- Volume
- 70
- Issue
- 10
- Pages
- 553-570
- ISSN
- 0029-6643 (ISSN-L)
- OpenAlex
- W2140741872
- Cited by
- 514
- References
- 9
- FWCI
- 25.31
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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