Digging into the construct of fibrofog: Psychometric properties of the Spanish version of the Multidimensional Inventory of Subjective Cognitive Impairment in patients with fibromyalgia
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Perceived dyscognition or fibrofog has been ranked as one major contributor of distress in fibromyalgia (FM). The Multidimensional Inventory of Subjective Cognitive Impairment (MISCI) was devised as a brief and comprehensive self‐report measure of cognitive function in FM. The main objective of the present study was to assess the psychometric properties of the Spanish version of the MISCI. One hundred and twenty patients with FM were included, and dimensionality, reliability, and validity of the MISCI were evaluated. Data from brain imaging (N = 61) were also used in validity analyses. Known‐groups validity was evaluated by including a subset of 45 patients without FM in partial/total remission from depression. Sensitivity to change was assessed after a mindfulness‐based intervention. Spanish version of the MISCI exhibited a one‐factor structure, excellent internal consistency, and good convergent validity with symptomatology and gray matter volumes in anterior and middle cingulate cortices. Significant improvements in MISCI scores after a mindfulness‐based intervention were reported. An additive effect of FM and depression regarding MISCI scores was also observed. Self‐reported depression, anxiety, and problems in balance predicted the 38% of the MISCI variance. The Spanish version of the MISCI is a valuable instrument to include in FM research and clinical practice.
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Fibromyalgia patients often have cognitive impairment (fibrofog) that can hinder understanding and application of intervention concepts.
“on the other hand, cognitive impairment that entails difficulties in abilities such as attention and memory, referred to as fibrofog, which could hinder their understanding and application of the concepts of the intervention [17].”
From Attachment-Based Compassion Therapy for Reducing Anxiety and Depression in Fibromyalgia (2022) · cites this paper as [17]
The Introduction reports that cognitive complaints are common in fibromyalgia, include memory and concentration difficulties, and are termed fibrofog. It does not say that fibrofog hinders patients’ understanding or application of intervention concepts; that consequence is an extrapolation. (LLM, conf=0.87)
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BackgroundSelf-citationGallego, A., Serrat, M., Royuela-Colomer, E., Sanabria‐Mazo, J. P., Borràs, X., Esteve, M., Grasa, M., Rosa, A., Rozadilla‐Sacanell, A., Almirall, M., et al. (2024) · Digital Health · doi:10.1177/20552076241239177 · Cited by 8 · see citing works
Self-citationRodríguez‐Freire, C., Navarrete, J., Rozadilla‐Sacanell, A., Sanabria‐Mazo, J. P., del Pino-Gaya, B., Borràs, X., Feliu‐Soler, A., & Luciano, J. V. (2026) · European Journal of Pain · doi:10.1002/ejp.70321 · Cited by 2 · see citing works
Self-citationSerrat, M., Royuela-Colomer, E., Auer, W., Ferrés, S., Almirall, M., Neblett, R., Nijs, J., Sanabria‐Mazo, J. P., Borràs, X., Luciano, J. V., et al. (2025) · Journal of Pain · doi:10.1016/j.jpain.2025.105514 · Cited by 1 · see citing works
Self-citation
- Authors
- Feliu‐Soler, A., Pérez‐Aranda, A., Andrés‐Rodríguez, L., Butjosa, A., Díaz, N. S., Trujols, J., Núñez, C., Stephan‐Otto, C., Rozadilla‐Sacanell, A., Serrano‐Blanco, A., Kratz, A. L., & Luciano, J. V.
- Affiliations
- Red de Investigación en Actividades Preventivas y Promoción de la Salud (ES)
- Parc Sanitari Sant Joan de Déu (ES)
- Hospital General de Agudos Dr. Enrique Tornú (AR)
- Hospital de Sant Pau (ES)
- Centro de Investigación Biomédica en Red de Salud Mental (ES)
- University of Michigan (US)
- Corresponding author
- Feliu‐Soler, Albert
- ORCID
- Venue
- Journal of Applied Biobehavioral Research
- Publisher
- Wiley
- Published
- 2018-06
- Volume
- 23
- Issue
- 2
- ISSN
- 1071-2089 (ISSN-L)
- 1751-9861
- OpenAlex
- W2805154277
- Cited by
- 12
- References
- 76
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 3 · 2020: 1 · 2019: 3 · 2018: 1
- FWCI
- 0.98
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Locations
- Journal of Applied Biobehavioral Research (publishedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- Funders
- Instituto de Salud Carlos III (CD16/00147, CP14/00087, RD16/0007/0012)
- Agència de Gestió d’Ajuts Universitaris i de Recerca (2017 FI_B 00754)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (1K01AR064275)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cancer-related cognitive impairment studies
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- fibromyalgia, subjective cognitive impairment, Spanish translation, psychometric properties, mindfulness-based interventions, depression, anxiety, balance problems, known-groups validity, sensitivity to change
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