Blood Pressure Control Provides Less Cardiovascular Protection in Adults With Than Without Apparent Treatment‐Resistant Hypertension
Open accessAbstract
Hypertension control may offer less protection from incident cardiovascular disease (CVDi) in adults with than without apparent treatment‐resistant hypertension (aTRH), ie, blood pressure uncontrolled while taking three or more antihypertensive medications or controlled to <140/<90 mm Hg while taking four or more antihypertensive medications. Electronic health data were matched to health claims for 2006–2012. Patients with CVDi in 2006–2007 or with untreated hypertension were excluded, leaving 118,356 treated hypertensives, including 40,690 with aTRH, and 460,599 observation years. Blood pressure and medication number were determined by all clinic visit means from 2008 to CVDi or end of study. Primary outcome was first CVDi (stroke, coronary heart disease, heart failure) from hospital and emergency department claims. Controlling for age, race, sex, diabetes, chronic kidney disease, and statin use, hypertension control afforded less CVDi protection in patients with aTRH (hazard ratio, 0.87; 95% confidence interval, 0.82–0.93) than without aTRH (hazard ratio, 0.69; 95% confidence interval, 0.65–0.74; P<.001). Strategies beyond hypertension control may prevent more CVDi in patients with aTRH.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In another study of more than 118,000 treated hypertensive adults, blood pressure control was associated with significantly lower rates of incident stroke and coronary heart disease with no difference in rates of incident heart failure.
“In another study of >118 000 treated hypertensive adults, including >40 000 individuals with RH and 460 000 observation-years, BP control was associated with significantly lower rates of incident stroke and coronary heart disease with no difference in rates of incident heart failure.37”
From Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association (2018) · cites this paper as [37]
Among patients with resistant hypertension, lower blood pressure is associated with reduced risk for some cardiovascular events.
“Among patients with RH, lower BP is associated with reduced risk for some cardiovascular events.28,37”
From Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association (2018) · cites this paper as [37]
Blood pressure control reduced the risk of incident stroke, coronary heart disease, or heart failure by 13% among those with resistant hypertension compared with a 31% lower risk of these outcomes among patients without resistant hypertension.
“BP control reduced the risk of incident stroke, coronary heart disease, or heart failure by 13% among those with RH compared with a 31% lower risk of these outcomes among patients without RH.37”
From Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association (2018) · cites this paper as [37]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Toprak, Ö., Kurt, H., Sarı, Y., Şarkış, C., Us, H., & Kırık, A. (2017) · Kidney & Blood Pressure Research · doi:10.1159/000468530 · Cited by 29,769 · see citing works
Chobanian, A. V., Bakris, G. L., Black, H. R., Cushman, W. C., Green, L. A., Izzo, J. L., Jones, D. W., Materson, B. J., Oparil, S., Wright, J. T., et al. (2003) · Hypertension · doi:10.1161/01.hyp.0000107251.49515.c2 · Cited by 13,271 · see citing works
James, P. A., Oparil, S., Carter, B. L., Cushman, W. C., Dennison-Himmelfarb, C., Handler, J., Lackland, D. T., LeFevre, M. L., MacKenzie, T. D., Ogedegbe, O., et al. (2014) · JAMA · doi:10.1001/jama.2013.284427 · Cited by 7,950 · see citing works
A Randomized Trial of Intensive versus Standard Blood-Pressure Control
The SPRINT Research Group (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1511939 · Cited by 6,325 · see citing works
Resistant Hypertension: Diagnosis, Evaluation, and Treatment
Calhoun, D. A., Jones, D. W., Textor, S. C., Goff, D. C., Murphy, T. P., Toto, R. D., White, A. J., Cushman, W. C., White, W. B., Sica, D. A., et al. (2008) · Circulation · doi:10.1161/circulationaha.108.189141 · Cited by 2,232 · see citing works
US trends in prevalence, awareness, treatment, and control of hypertension, 1988–2008
Egan, B. M. (2010) · JAMA · doi:10.1001/jama.2010.650 · Cited by 2,197 · see citing works
Self-citationA Controlled Trial of Renal Denervation for Resistant Hypertension
Bhatt, D. L., Kandzari, D. E., O'Neill, W. W., D'Agostino, R., Flack, J. M., Katzen, B. T., Leon, M. B., Liu, M., Mauri, L., Negoita, M., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1402670 · Cited by 2,186 · see citing works
Statins for the primary prevention of cardiovascular disease
Taylor, F., Huffman, M. D., Macedo, A. F., Moore, T. H., Burke, M., Davey Smith, G., Ward, K., Ebrahim, S., & Gay, H. C. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004816.pub5 · Cited by 1,934 · see citing works
Resistant Hypertension: Diagnosis, Evaluation, and Treatment
Calhoun, D. A., Jones, D. W., Textor, S. C., Goff, D. C., Murphy, T. P., Toto, R. D., White, A. J., Cushman, W. C., White, W. B., Sica, D. A., et al. (2008) · Hypertension · doi:10.1161/hypertensionaha.108.189141 · Cited by 1,404 · see citing works
Dolan, E., Stanton, A., Thijs, L., Hinedi, K., Atkins, N., McClory, S., Hond, E. D., McCormack, P., Staessen, J. A., & O’Brien, E. (2005) · Hypertension · doi:10.1161/01.hyp.0000170138.56903.7a · Cited by 1,227 · see citing works
Weber, M. A., Schiffrin, E. L., White, W. B., Mann, S., Lindholm, L. H., Kenerson, J. G., Flack, J. M., Carter, B. L., Materson, B. J., Ram, C. V. S., et al. (2014) · The Journal of Clinical Hypertension · doi:10.1111/jch.12237 · Cited by 986 · see citing works
Incidence and Prognosis of Resistant Hypertension in Hypertensive Patients
Daugherty, S. L., Powers, J. D., Magid, D. J., Tavel, H. M., Masoudi, F. A., Margolis, K. L., O'Connor, P. J., Selby, J. V., & Ho, P. M. (2012) · Circulation · doi:10.1161/circulationaha.111.068064 · Cited by 930 · see citing works
Tyson, C. C., & Coffman, T. M. (2017) · The Nephron journals/Nephron journals · doi:10.1159/000455130 · Cited by 710 · see citing works
Clinical Practice Guidelines for the Management of Hypertension in the Community
Weber, M. A., Schiffrin, E. L., White, W. B., Mann, S. J., Lindholm, L. H., Kenerson, J. G., Flack, J. M., Carter, B. L., Materson, B. J., Ram, C. V. S., et al. (2013) · Journal of Hypertension · doi:10.1097/hjh.0000000000000065 · Cited by 681 · see citing works
Kleinbaum, D. G., & Klein, M. (2005) · Statistics in the health sciences · doi:10.1007/0-387-29150-4 · Cited by 679 · see citing works
A Randomized Trial of Intensive versus Standard Blood-Pressure Control
Bangalore, S., Rimoldi, S., & Messerli, F. H. (2016) · New England Journal of Medicine · doi:10.1056/nejmc1602668 · Cited by 652 · see citing works
Cooper-DeHoff, R. M., Gong, Y., Handberg, E. M., Bavry, A. A., Denardo, S. J., Bakris, G. L., & Pepine, C. J. (2010) · JAMA · doi:10.1001/jama.2010.884 · Cited by 651 · see citing works
Uncontrolled and Apparent Treatment Resistant Hypertension in the United States, 1988 to 2008
Egan, B. M., Zhao, Y., Axon, R. N., Brzezinski, W. A., & Ferdinand, K. C. (2011) · Circulation · doi:10.1161/circulationaha.111.030189 · Cited by 599 · see citing works
Self-citationTrends in Dietary Quality Among Adults in the United States, 1999 Through 2010
Wang, D. D., Leung, C. W., Li, Y., Ding, E. L., Chiuve, S. E., Hu, F. B., & Willett, W. C. (2014) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2014.3422 · Cited by 497 · see citing works
Renal Sympathetic Denervation for Treatment of Drug-Resistant Hypertension
Esler, M., Krum, H., Schlaich, M. P., Schmieder, R. E., Böhm, M., & Sobotka, P. A. (2012) · Circulation · doi:10.1161/circulationaha.112.130880 · Cited by 462 · see citing works
Mellen, P. B., Gao, S. K., Vitolins, M. Z., & Goff, D. C. (2008) · Archives of Internal Medicine · doi:10.1001/archinternmed.2007.119 · Cited by 444 · see citing works
Management of High Blood Pressure in Blacks
Flack, J. M., Sica, D. A., Bakris, G. L., Brown, A. L., Ferdinand, K. C., Grimm, R. H., Hall, W. D., Jones, W. E., Kountz, D. S., Lea, J. P., et al. (2010) · Hypertension · doi:10.1161/hypertensionaha.110.152892 · Cited by 444 · see citing works
PIERDOMENICO, S., LAPENNA, D., BUCCI, A., DITOMMASO, R., DIMASCIO, R., MANENTE, B., CALDARELLA, M., NERI, M., CUCCURULLO, F., & MEZZETTI, A. (2005) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2005.05.014 · Cited by 409 · see citing works
Moser, M., & Hebert, P. R. (1996) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(95)00606-0 · Cited by 344 · see citing works
Statins for the primary prevention of cardiovascular disease
Ebrahim, S. B. J., Taylor, F. C., & Brindle, P. (2014) · BMJ · doi:10.1136/bmj.g280 · Cited by 331 · see citing works
Go, A. S., Bauman, M. A., Coleman King, S. M., Fonarow, G. C., Lawrence, W., Williams, K. A., & Sanchez, E. (2014) · Hypertension · doi:10.1161/hyp.0000000000000003 · Cited by 306 · see citing works
Prognostic Influence of Office and Ambulatory Blood Pressures in Resistant Hypertension
Salles, G. F., Cardoso, C. R. L., & Muxfeldt, E. S. (2008) · Archives of Internal Medicine · doi:10.1001/archinte.168.21.2340 · Cited by 293 · see citing works
Masked hypertension: A systematic review
Bobrie, G., Clerson, P., Ménard, J., Postel-Vinay, N., Chatellier, G., & Plouin, P.-F. (2008) · Journal of Hypertension · doi:10.1097/hjh.0b013e3282fbcedf · Cited by 279 · see citing works
Hebert, P. R. (1993) · Archives of Internal Medicine · doi:10.1001/archinte.1993.00410050018004 · Cited by 253 · see citing works
The J-Curve Between Blood Pressure and Coronary Artery Disease or Essential Hypertension
Messerli, F. H., & Panjrath, G. S. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.05.073 · Cited by 251 · see citing works
Bakris, G. L., Nadim, M. K., Haller, H. G., Lovett, E. G., Schafer, J. E., & Bisognano, J. D. (2012) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2012.01.003 · Cited by 246 · see citing works
Racial Differences in the Impact of Elevated Systolic Blood Pressure on Stroke Risk
Howard, G., Lackland, D. T., Kleindorfer, D., D, B. M. K. M., Moy, C. S., Judd, S. E., Safford, M. M., Cushman, M., Glasser, S. P., & Howard, V. J. (2012) · JAMA Internal Medicine · doi:10.1001/2013.jamainternmed.857 · Cited by 234 · see citing works
Muntner, P., Davis, B. R., Cushman, W. C., Bangalore, S., Calhoun, D. A., Pressel, S. L., Black, H. R., Kostis, J. B., Probstfield, J. L., Whelton, P. K., et al. (2014) · Hypertension · doi:10.1161/hypertensionaha.114.03850 · Cited by 231 · see citing works
Irvin, M. R., Booth, J. N., Shimbo, D., Lackland, D. T., Oparil, S., Howard, G., Safford, M. M., Muntner, P., & Calhoun, D. A. (2014) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2014.03.003 · Cited by 146 · see citing works
Egan, B. M., Basile, J., Rehman, S. U., Davis, P. B., Grob, C. H., RIEHLE, J., Walters, C., Lackland, D. T., Merali, C., Sealey, J. E., et al. (2009) · American Journal of Hypertension · doi:10.1038/ajh.2009.63 · Cited by 131 · see citing works
Self-citationBangalore, S., Fayyad, R., Laskey, R., DeMicco, D. A., Deedwania, P., Kostis, J. B., & Messerli, F. H. (2014) · The American Journal of Medicine · doi:10.1016/j.amjmed.2013.07.038 · Cited by 93 · see citing works
Systolic Blood Pressure and Cardiovascular Outcomes During Treatment of Hypertension
Weber, M. A., Bakris, G. L., Hester, A., Weir, M. R., Hua, T. A., Zappe, D., Dahlöf, B., Velazquez, E. J., Pitt, B., & Jamerson, K. (2013) · The American Journal of Medicine · doi:10.1016/j.amjmed.2013.01.007 · Cited by 64 · see citing works
Ford, E. S., Zhao, G., Li, C., Pearson, W. S., & Mokdad, A. H. (2008) · American Journal of Hypertension · doi:10.1038/ajh.2008.246 · Cited by 58 · see citing works
Closing the Gap in Hypertension Control Between Younger and Older Adults
Egan, B. M., Li, J., Shatat, I. F., Fuller, J., & Sinopoli, A. (2014) · Circulation · doi:10.1161/circulationaha.113.007699 · Cited by 44 · see citing works
Self-citationEgan, B. M., & Zhao, Y. (2012) · Journal of Clinical Hypertension · doi:10.1111/jch.12057 · Cited by 40 · see citing works
Self-citationGenetics, Ancestry, and Hypertension: Implications for Targeted Antihypertensive Therapies
Franceschini, N., Chasman, D., Cooper-DeHoff, R., & Arnett, D. (2014) · Current Hypertension Reports · doi:10.1007/s11906-014-0461-9 · Cited by 39 · see citing works
Cardiovascular outcomes in hypertensive patients
Weber, M. A., Julius, S., Kjeldsen, S. E., Jia, Y., Brunner, H. R., Zappe, D., Hua, T. A., McInnes, G. T., Schork, A. M., Mancia, G., et al. (2012) · Journal of Hypertension · doi:10.1097/hjh.0b013e3283582ed6 · Cited by 28 · see citing works
Smith, G. D., Dyson, K., Taylor, D. M., Morgans, A., Holdgate, A., & Cantwell, K. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009502 · Cited by 27 · see citing works
Flagged first, then by citations
1 of the 46 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- [22]Breslow NE Day NE Modelling the relationship between risk, dose, and time International Agency for Research on Cancer. Statistical Method in Cancer Research: The Design and Analysis of Cohort Data Lyon, France Oxford University Press 1987 232 70
- [23]Greenland S Applications of Stratified Analysis Methods Modern Epidemiology 3 Rothman KJ Greenland S Lash TL Philadelphia, USA Lippincott Williams & Wilkins 2008 283 302
Cited by
Sorted by citations
Carey, R. M., Calhoun, D. A., Bakris, G. L., Brook, R. D., Daugherty, S. L., Dennison-Himmelfarb, C. R., Egan, B. M., Flack, J. M., Gidding, S. S., Judd, E., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000084 · Cited by 1,153 · see citing works
Self-citationTreatment of Resistant and Refractory Hypertension
Acelajado, M. C., Hughes, Z. H., Oparil, S., & Calhoun, D. A. (2019) · Circulation Research · doi:10.1161/circresaha.118.312156 · Cited by 219 · see citing works
The global burden of hypertension exceeds 1.4 billion people
Egan, B. M., Kjeldsen, S. E., Grassi, G. M., Esler, M., & Mancia, G. (2019) · Journal of Hypertension · doi:10.1097/hjh.0000000000002021 · Cited by 197 · see citing works
Self-citationResistant Hypertension in People With CKD: A Review
Fay, K., & Cohen, D. L. (2020) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2020.04.017 · Cited by 79 · see citing works
The Burden of Resistant Hypertension Across the World
Brant, L. C. C., Passaglia, L. G., Filho, M. M. P., de Castilho, F. M., Ribeiro, A. L. P., & Nascimento, B. R. (2022) · Current Hypertension Reports · doi:10.1007/s11906-022-01173-w · Cited by 56 · see citing works
Viazzi, F. C., Piscitelli, P. A., Ceriello, A., Fioretto, P., Giorda, C. B., Guida, P., Russo, G. T., Cosmo, S. D., Pontremoli, R., & AMD‐Annals Study Group (2017) · Journal of the American Heart Association · doi:10.1161/jaha.117.006745 · Cited by 34 · see citing works
Ebinger, J. E., Gluckman, T. J., Magraner, J., Chiu, S. T., Rider, D., Thomas, C., Das, S. R., Ho, P. M., Shreenivas, S., & Bradley, S. M. (2023) · Hypertension · doi:10.1161/hypertensionaha.123.20894 · Cited by 25 · see citing works
Владимировна, А. А., Анатольевна, С. О., Blinova, N. V., Danilov, N. M., Elfimova, E. M., Кislyak, O. A., Litvin, A. Y., Ощепкова, Е. В., Fomin, V. V., Михайловна, Ч. Н., et al. (2021) · Terapevticheskii arkhiv · doi:10.26442/00403660.2021.09.201007 · Cited by 28 · see citing works
The Global Burden of Resistant Hypertension and Potential Treatment Options
Buso, G., Rosei, C. A., Lemoli, M., Corvini, F., & Muiesan, M. L. (2024) · European Cardiology Review · doi:10.15420/ecr.2023.51 · Cited by 29 · see citing works
Viazzi, F. C., Greco, E., Ceriello, A., Fioretto, P., Giorda, C. B., Guida, P., Russo, G. T., Cosmo, S. D., Pontremoli, R., & AMD-Annals Study Group (2018) · Kidney & Blood Pressure Research · doi:10.1159/000488255 · Cited by 24 · see citing works
Ostrominski, J. W., Vaduganathan, M., Selvaraj, S., Claggett, B. L., Miao, Z. M., Desai, A. S., Jhund, P. S., Kosiborod, M., Lam, C. S. P., Inzucchi, S. E., et al. (2023) · Circulation · doi:10.1161/circulationaha.123.065254 · Cited by 24 · see citing works
Jafari, E. A., Cooper‐DeHoff, R. M., Effron, M. B., Hogan, W. R., & McDonough, C. W. (2023) · American Journal of Hypertension · doi:10.1093/ajh/hpad084 · Cited by 20 · see citing works
Smith, S. M., Gurka, M. J., Calhoun, D. A., Gong, Y., Pepine, C. J., & Cooper‐DeHoff, R. M. (2018) · The American Journal of Medicine · doi:10.1016/j.amjmed.2018.08.005 · Cited by 17 · see citing works
Egan, B. M., Kai, B., Wagner, C. S., Fleming, D. O., Henderson, J. H., Chandler, A. H., & Sinopoli, A. (2016) · Journal of Clinical Hypertension · doi:10.1111/jch.12904 · Cited by 13 · see citing works
Self-citationChun, K., Lee, C. J., Oh, J., Lee, S., Kang, S., Kario, K., & Park, S. (2020) · Journal of Clinical Hypertension · doi:10.1111/jch.14043 · Cited by 12 · see citing works
Chattranukulchai, P., Roubsanthisuk, W., Kunanon, S., Kotruchin, P., Satirapoj, B., Wongpraparut, N., Sunthornyothin, S., & Sukonthasarn, A. (2024) · Hypertension Research · doi:10.1038/s41440-024-01785-6 · Cited by 11 · see citing works
Renal denervation: Alternative treatment options for hypertension?
Gupta, A. A., Prince, M., Bob‐Manuel, T., & Jenkins, J. S. (2019) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2019.12.007 · Cited by 10 · see citing works
Nonpharmacological Management of Resistant Hypertension
Sabbahi, A., Severin, R. S., Laddu, D., Sharman, J. E., Arena, R. A., & Ozemek, C. (2021) · Current Cardiology Reports · doi:10.1007/s11886-021-01601-4 · Cited by 9 · see citing works
Pioli, M. R., Ritter, A. M. V., & Modolo, R. (2017) · American Journal of Hypertension · doi:10.1093/ajh/hpx204 · Cited by 7 · see citing works
Carey, R. M. (2018) · Hypertension · doi:10.1161/hypertensionaha.118.12270 · Cited by 7 · see citing works
Abiodun, O. O., Anya, T., Chukwu, J. C., & Adekanmbi, V. (2024) · Global Heart · doi:10.5334/gh.1296 · Cited by 5 · see citing works
Resistant hypertension: focus on vascular lesions
Сергеевна, Л. М., Хаишева, Л. А., & Shlyk, S. V. (2020) · South Russian Journal of Therapeutic Practice · doi:10.21886/2712-8156-2020-1-3-16-26 · Cited by 2 · see citing works
Kgatla, M. N., Mothiba, T. M., Malema, R. N., Makgahlela, M., & Sodi, T. (2022) · The Open Public Health Journal · doi:10.2174/18749445-v16-e2205311 · Cited by 1 · see citing works
Volpe, M., & Gallo, G. (2022) · European Heart Journal Supplements · doi:10.1093/eurheartjsupp/suac094 · Cited by 1 · see citing works
Hipertensión arterial refractaria al tratamiento. Definiciones y manejo actualizado
Espinoza, A. E. R., & Castro, A. S. B. (2023) · LATAM Revista Latinoamericana de Ciencias Sociales y Humanidades · doi:10.56712/latam.v4i2.1017 · Cited by 2 · see citing works
Manolis, A. J. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.734299250.793571584 · Cited by 1 · see citing works
Resistant arterial hypertension and treatment methods
Tomas, I. (2023) · Galenika Medical Journal · doi:10.5937/galmed2306070t
Abuelsoud, N. N., & Abdelraouf, F. H. (2025) · Research Journal of Pharmacy and Technology · doi:10.52711/0974-360x.2025.00124
Meena, M., Khan, Y., Joshi, R. P., Shah, B., Galwankar, S., & Agrawal, A. (2025) · International Journal of Research in Medical Sciences · doi:10.18203/2320-6012.ijrms20253618
Wasiliew, S., Lipski, D., Stryczyński, Ł., Radziemski, A., Królak, J., Tykarski, A., & Uruski, P. (2025) · Artery Research · doi:10.1007/s44200-025-00095-7
Management Strategies for Treatment-Resistant Hypertension: Current Status and Future Outlook
Thakare, S. B., Anandh, U., & Dasgupta, I. (2026) · Indian Journal of Nephrology · doi:10.25259/ijn_658_2025
- Authors
- Egan, B. M., Kai, B., Wagner, C. S., Henderson, J. H., Chandler, A. H., & Sinopoli, A.
- Affiliations
- Prisma Health (US)
- College of Charleston (US)
- University of South Carolina (US)
- Corresponding author
- Egan, Brent M.
- Venue
- The Journal of Clinical Hypertension
- Publisher
- Wiley
- Published
- 2016-02-09
- Volume
- 18
- Issue
- 8
- Pages
- 817-824
- ISSN
- 1524-6175 (ISSN-L)
- 1751-7176
- PMC
- PMC5837039
- OpenAlex
- W2253820963
- Cited by
- 32
- References
- 46
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 5 · 2022: 3 · 2021: 2 · 2020: 4 · 2019: 3 · 2018: 5 · 2017: 2 · 2016: 1
- FWCI
- 3.02
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Clinical Hypertension (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Medtronic
- National Institutes of Health (HL105880)
- Centers for Disease Control and Prevention
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
- Keywords
- treatment-resistant hypertension, blood pressure control, cardiovascular disease incidence, antihypertensive medication burden, cardioprotection, stroke, coronary artery disease, heart failure, hypertension
- MeSH terms
- Adult, Antihypertensive Agents, Blood Pressure, Blood Pressure Determination, Cardiovascular Diseases, Emergency Medical Services, Female, Humans, Hypertension, Male, Middle Aged, Risk Factors, Prevalence, Treatment Failure
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
