The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Evidence that periodontal treatment improves diabetes outcomes: a systematic review and meta‐analysis
Open accessAbstract
Context: The effect of periodontal therapy on diabetes outcomes has not been established. Objective: This update examines the effect of periodontal treatment on diabetes outcomes. Data sources: Literature since October 2009 using MEDLINE. Study eligibility criteria: Published RCT s including periodontal therapy for diabetic subjects, a metabolic outcome, an untreated control group, and follow‐up of 3 months. Data extraction: Pre‐defined data fields, including study quality indicators were used. Data synthesis: A search revealed 56 publications of which 9 met inclusion criteria. Mean change of HbA1c from baseline was compared across treatment groups. Pooled analysis was based on random effects models. Results: A meta‐analysis indicated a mean treatment effect of −0.36% HbA1c (CI −0.54, −0.19) compared to no treatment after periodontal therapy (p < 0.0001). Heterogeneity tests revealed only minimal evidence of publication bias (I2 = 9%). Limitations: Small sample size and high risk of bias remain problematic for studies of this type. Periodontal therapy varied considerably. Conclusion: The modest reduction in HbA1c observed as a result of periodontal therapy in subjects with type 2 diabetes is consistent with previous systematic reviews. Despite this finding, there is limited confidence in the conclusion due to a lack of multi‐centre trials of sufficient sample size are lacking.
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Cites
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Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes
Hundal, R. S., Petersen, K. F., Mayerson, A. B., Randhawa, P. S., Inzucchi, S., Shoelson, S. E., & Shulman, G. I. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0214955 · Cited by 557
A Review of Diabetes Treatment Adherence and the Association with Clinical and Economic Outcomes
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“Elevated HbA1c has been linked to micro- and macro- vascular diabetes complications (Engelgau et al. 1997, Knowler et al. 2002, ADA 2003).”
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Cited by
Chapple, I. L. C., Genco, R., & on behalf of working group 2 of the joint EFP/AAP workshop (2013) · Journal of Periodontology · doi:10.1902/jop.2013.1340011 · Cited by 852
Sanz, M., Ceriello, A., Buysschaert, M., Chapple, I., Demmer, R. T., Graziani, F., Herrera, D., Jepsen, S., Lione, L., Madianos, P., et al. (2018) · Journal of Clinical Periodontology · doi:10.1111/jcpe.12808 · Cited by 738
Japanese clinical practice guideline for diabetes 2019
Araki, E., Goto, A., Kondo, T., Noda, M., Noto, H., Origasa, H., Osawa, H., Taguchi, A., Tanizawa, Y., Tobe, K., et al. (2020) · Diabetology International · doi:10.1007/s13340-020-00439-5 · Cited by 545
Epidemiologic relationship between periodontitis and type 2 diabetes mellitus
Wu, C.-Z., Yuan, Y.-H., Liu, H.-H., Li, S.-S., Zhang, B.-W., Chen, W., An, Z.-J., Chen, S.-Y., Wu, Y.-Z., Han, B., et al. (2020) · BMC Oral Health · doi:10.1186/s12903-020-01180-w · Cited by 429
An update on the evidence for pathogenic mechanisms that may link periodontitis and diabetes
Polak, D., & Shapira, L. (2018) · Journal of Clinical Periodontology · doi:10.1111/jcpe.12803 · Cited by 396
Metadata
- Authors
- Engebretson, S., & Kocher, T.
- Venue
- Journal of Clinical Periodontology
- Publisher
- Wiley
- Published
- 2013-04
- Volume
- 40
- Issue
- s14
- Pages
- S153-63
- ISSN
- 0303-6979 (ISSN-L)
- 1600-051X
- OpenAlex
- W1967674644
- Cited by
- 236
- References
- 7
- FWCI
- 5.87
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
