Cited by 1,066Dental Implant Techniques and OutcomesOral microbiology and periodontitis researchPeriodontal Regeneration and Treatments

The DOI matches its Crossref record; 165 of the 166 references it cites were found in a registry or an index.

Peri‐implantitis

Open access

Schwarz, Frank, Derks, Jan, Monje, Alberto, Wang, Hom‐Lay·2018·Journal of Clinical Periodontology

DOI 10.1111/jcpe.12954

Open this paper in CoChat — free account Open PDF

Abstract

Objectives: This narrative review provides an evidence‐based overview on peri‐implantitis for the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions. Methods: A literature review was conducted addressing the following topics: 1) definition of peri‐implantitis; 2) conversion from peri‐implant mucositis to peri‐implantitis, 3) onset and pattern of disease progression, 4) characteristics of peri‐implantitis, 5) risk factors/indicators for peri‐implantitis, and 6) progressive crestal bone loss in the absence of soft tissue inflammation. Conclusions: Peri‐implantitis is a pathological condition occurring in tissues around dental implants, characterized by inflammation in the peri‐implant connective tissue and progressive loss of supporting bone. The histopathologic and clinical conditions leading to the conversion from peri‐implant mucositis to peri‐implantitis are not completely understood. The onset of peri‐implantitis may occur early during follow‐up and the disease progresses in a non‐linear and accelerating pattern. Peri‐implantitis sites exhibit clinical signs of inflammation and increased probing depths compared to baseline measurements. At the histologic level, compared to periodontitis sites, peri‐implantitis sites often have larger inflammatory lesions. Surgical entry at peri‐implantitis sites often reveals a circumferential pattern of bone loss. There is strong evidence that there is an increased risk of developing peri‐implantitis in patients who have a history of chronic periodontitis, poor plaque control skills, and no regular maintenance care after implant therapy. Data identifying “smoking” and “diabetes” as potential risk factors/indicators for peri‐implantitis are inconclusive. There is some limited evidence linking peri‐implantitis to other factors such as: post‐restorative presence of submucosal cement, lack of peri‐implant keratinized mucosa and positioning of implants that make it difficult to perform oral hygiene and maintenance. Evidence suggests that progressive crestal bone loss around implants in the absence of clinical signs of soft tissue inflammation is a rare event.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1111/jcpe.12954

Cites

165 of 165 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Global estimates of the prevalence of diabetes for 2010 and 2030
Shaw, J. E., Sicree, R. A., & Zimmet, P. Z. (2010) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2009.10.007 · Cited by 7,216
Global Burden of Severe Periodontitis in 1990-2010: A Systematic Review and Meta-regression
Kassebaum, N. J., Bernabé, E., Dahiya, M., Bhandari, B., Murray, C. J. L., & Marcenes, W. (2014) · Journal of Dental Research · doi:10.1177/0022034514552491 · Cited by 2,209
Peri‐implant diseases: Consensus Report of the Sixth European Workshop on Periodontology
Lindhe, J., Meyle, J., & on behalf of Group D of the European Workshop on Periodontology (2008) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.2008.01283.x · Cited by 1,524
Update on Prevalence of Periodontitis in Adults in the United States: NHANES 2009 – 2012
Eke, P., Dye, B., Wei, L., Slade, G., Thornton-Evans, G., Borgnakke, W., Taylor, G., Page, R., Beck, J., & Genco, R. (2015) · The Journal of Periodontology · doi:10.1902/jop.2015.140520 · Cited by 1,442
Risk factors for periodontal disease
Genco, R. J., & Borgnakke, W. S. (2013) · Periodontology 2000 · doi:10.1111/j.1600-0757.2012.00457.x · Cited by 1,307
Smoking‐Attributable Periodontitis in the United States: Findings From NHANES III
Tomar, S. L., & Asma, S. (2000) · Journal of Periodontology · doi:10.1902/jop.2000.71.5.743 · Cited by 1,002
Periimplant diseases: where are we now?--Consensus of the Seventh European Workshop on Periodontology
Lang, N. P., Berglundh, T., & on Behalf of Working Group 4 of the Seventh European Workshop on Periodontology (2011) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.2010.01674.x · Cited by 930
The long‐term effect of a plaque control program on tooth mortality, caries and periodontal disease in adults
Axelsson, P., Nyström, B., & Lindhe, J. (2004) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.2004.00563.x · Cited by 902
A prospective 15‐year follow‐up study of mandibular fixed prostheses supported by osseointegrated implants. Clinical results and marginal bone loss.
Lindquist, L. W., Carlsson, G. E., & Jemt, T. (1996) · Clinical Oral Implants Research · doi:10.1034/j.1600-0501.1996.070405.x · Cited by 700
Experimental breakdown of peri‐implant and periodontal tissues. A study in the beagle dog
Lindhe, J., Berglundh, T., Ericsson, I., Liljenberg, B., & Marinello, C. P. (1992) · Clinical Oral Implants Research · doi:10.1034/j.1600-0501.1992.030102.x · Cited by 667

Show all 166 references

Research works printed but not linked: 1

Hanselaer L, 2010, De Bruyn H. [Giant cell peripheral granuloma surrounding a dental implant: case report], Revue Belge de Medicine Dentaire (1984), 65, 152

Sorted by citations

Items 501–600 of 1,002

Visualized analysis of hotspots and frontiers in diabetes-associated periodontal disease research: a bibliometric study
Gao, B., Wu, J., Lv, K., Shen, C., & Yao, H. (2022) · Annals of Translational Medicine · doi:10.21037/atm-22-2443 · Cited by 7
Regulation of endothelial cells on the osteogenic ability of bone marrow mesenchymal stem cells in peri-implantitis
Xia, Y., Geng, N., Ren, J., Liao, C., Wang, M., Chen, S., Chen, H., & Peng, W. J. (2023) · Tissue and Cell · doi:10.1016/j.tice.2023.102042 · Cited by 7
The efficacy of a porcine collagen matrix in keratinized mucosa width augmentation: a 10-year follow-up clinical prospective study
Manfredini, M., Poli, P. P., Guerrieri, P., Beretta, M., & Maiorana, C. (2023) · International Journal of Implant Dentistry · doi:10.1186/s40729-023-00475-1 · Cited by 7
A Systematic Review and Meta-Analysis of the Clinical Outcomes for Adjunctive Physical, Chemical, and Biological Treatment of Dental Implants With Peri-Implantitis
Zakir, M., Thomas, D. W., Adams, R. J., FARNELL, D. J. J., & Claydon, N. (2023) · Journal of Oral Implantology · doi:10.1563/aaid-joi-d-21-00204 · Cited by 7
Effectiveness of antimicrobial photodynamic therapy in the treatment of peri-implantitis: systematic review and meta-analysis
da Fonseca, V. C. P., Abreu, L. G., Andrade, É., Asquino, N., & Lima, R. P. E. (2024) · Lasers in Medical Science · doi:10.1007/s10103-024-04135-7 · Cited by 7
Evaluation of peri‐implant tissues condition after 10–15 years of loading in treated chronic periodontitis patients attending a private practice setting: A retrospective study
Guarnieri, R., Nardo, D. D., Giorgio, G. D., Miccoli, G., & Testarelli, L. (2021) · Clinical Oral Implants Research · doi:10.1111/clr.13712 · Cited by 7
Influence of antiresorptive/antiangiogenic therapy on the extension of experimentally induced peri-implantitis lesions
Schwarz, F., Becker, K., Lukman, F., Müller, K. M., Sarabhai, V., Rauch, N., Kerberger, R., Ramanauskaitė, A., Sader, R., & Obreja, K. (2023) · Clinical Oral Investigations · doi:10.1007/s00784-023-04904-8 · Cited by 7
Self-citation
Novel Antibiotic-Loaded PEGylated Xerogels of Acidified Chitosan for Periodontal Diseases
Zafar, F., Sheraz, M. A., Ali, S. A., Riaz, M., Ahmed, S., & Anwar, Z. (2025) · Current Drug Delivery · doi:10.2174/0115672018377472250326061736 · Cited by 6
Peri‐implantitis reconstructive treatment implementing a titanium brush: 5‐year extension results from a randomized clinical trial
de Tapia, B., Ribeiro‐Amaral, T., Mor, C., Nart, J., & Valles, C. (2025) · Journal of Periodontology · doi:10.1002/jper.24-0673 · Cited by 6
Efficacy of implantoplasty in the treatment of peri-implantitis: A 24-month randomized controlled clinical trial
Cruz, R. K. S., Freire, G. C. B., Viana, J. C. M., Simão, C. E. D. P. C. N., Dutra, A. M. R., Silva, A. P., Roncalli, Â. G., & Gurgel, B. C. D. V. (2025) · Journal of Dentistry · doi:10.1016/j.jdent.2025.105844 · Cited by 6
One-piece zirconia oral implants supporting three-unit fixed dental prostheses: Ten-year results from a prospective case series
Kohal, R., Komine, F., Lith, A., Spies, B. C., Burkhardt, F., & Vach, K. (2025) · Journal of Dentistry · doi:10.1016/j.jdent.2025.105911 · Cited by 7
Impact of rose bengal-mediated antimicrobial photodynamic therapy adjunctive to mechanical debridement on clinical, microbiological, and immunological parameters in peri-implantitis: a parallel, single-blinded, randomized controlled trial
Nedumaran, N., & Rajasekar, A. (2025) · Lasers in Medical Science · doi:10.1007/s10103-025-04548-y · Cited by 6
Surface-specific outcomes of mechanical debridement with titanium, chitosan and nitinol brushes on titanium dental implant surfaces
Lauretis, A. D., Santacroce, M., Ellingsen, J. E., Lyngstadaas, S. P., Linke, D., & Haugen, H. J. (2025) · Journal of Dentistry · doi:10.1016/j.jdent.2025.106010 · Cited by 6
Clinical performance of short implants vs. standard implants in edentulous patients. An umbrella review
Arbildo-Vega, H. I., Cruzado-Oliva, F. H., Infantes, E., Luján-Valencia, S. A., Meza-Málaga, J. M., Soto, C. M., & Coronel-Zubiate, F. T. (2025) · Frontiers in Oral Health · doi:10.3389/froh.2025.1670095 · Cited by 6
Ten‐Year Results of a Prospective Study on One‐Piece Zirconia Oral Implants for Single‐Tooth Reconstruction
Kohal, R., Lith, A., Komine, F., Honda, J., Spies, B. C., Burkhardt, F., & Vach, K. (2025) · Clinical Oral Implants Research · doi:10.1111/clr.70049 · Cited by 6
Reconceptualizing Peri‐Implantitis: Dual‐Factor Inflammation and Its Role in Advancing Biomaterial Coatings
Cunha, D. M., Santana, A. P., Guerreiro, M. M., Chaurasia, A., Sculean, A., de Molon, R. S., & de Ávila, É. D. (2026) · Clinical Implant Dentistry and Related Research · doi:10.1111/cid.70108 · Cited by 6
Treatment of advanced peri-implantitis with regenerative therapy: a review of the rationale, technique, and outcomes
Froum, S. (2021) · Frontiers of Oral and Maxillofacial Medicine · doi:10.21037/fomm-21-30 · Cited by 6
Apical Papilla Regulates Dental Follicle Fate via the OGN-Hh Pathway
Lin, X., Li, Q., Hu, L., Jiang, C., Wang, S., & Wu, X. (2022) · Journal of Dental Research · doi:10.1177/00220345221138517 · Cited by 6
Treatment of Peri-implant Diseases using Lasers: A Systematic Review
AlMarzooqi, A. M. A., Ramachandra, S. S., Kukreja, B. J., Reddy, S., Souza, J. L. D., & Abdelmagyd, H. (2023) · The Open Dentistry Journal · doi:10.2174/18742106-v17-e230517-2022-143 · Cited by 6
Effect of Enterococcus faecalis Biofilm on Corrosion Kinetics in Titanium Grade 4 Alloys with Different Surface Treatments
Conforte, J. J., de Sousa, C. A., da Silva, A. C. R., Ribeiro, A. V., Duque, C., & Assunção, W. G. (2023) · Materials · doi:10.3390/ma16134532 · Cited by 6
Adjunctive benefit of probiotic supplementation along with nonsurgical therapy for peri-implant diseases – A systematic review and meta-analysis
Ambili, R., & Nazimudeen, N. B. (2023) · Journal of Indian Society of Periodontology · doi:10.4103/jisp.jisp_308_22 · Cited by 6
Evaluation of the effect of photodynamic therapy with Curcumin and Riboflavin on implant surface contaminated with Aggregatibacter actinomycetemcomitans
Etemadi, A., Hashemi, S. S., & Chiniforush, N. (2023) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2023.103833 · Cited by 6
Knowledge and attitude of dental students regarding etiology, diagnosis, and treatment of peri‐implantitis
Madi, M. I., Tabassum, A., Attia, D., AlMuhaish, L., AlMutiri, H., Alshehri, T., Zakaria, O., & Al-Jandan, B. (2023) · Journal of Dental Education · doi:10.1002/jdd.13397 · Cited by 6
Prescription of antibiotic prophylaxis in implant placement among Portuguese dentists: A web survey
Correia, F., Ribeiro‐Vidal, H., Gouveia, S., & Almeida, R. F. (2023) · Clinical Oral Implants Research · doi:10.1111/clr.14218 · Cited by 6
Dose- and time-dependent association of smoking and its cessation with risk of peri-implant diseases
Majid, O. W. (2023) · Evidence-Based Dentistry · doi:10.1038/s41432-023-00957-6 · Cited by 6
Analysis of subgingival bacterial and fungal diversity in patients with peri-implantitis based on 16sRNA and internal transcribed spacer sequencing
Chen, S., He, F., & Cheng, X. (2023) · Future Microbiology · doi:10.2217/fmb-2023-0228 · Cited by 6
Development and applications of peri‐implantitis mouse models
Zhang, J., Tong, Z., Chen, L., Qian, Y., Lu, Y., Chen, Q., & Si, M. (2024) · Oral Diseases · doi:10.1111/odi.14929 · Cited by 6
High-Intensity Focused Ultrasound in Dentistry: A Literature Review
Tran, M. D., Ngo, H. C., & Fawzy, A. (2024) · International Dental Journal · doi:10.1016/j.identj.2024.02.004 · Cited by 6
The influence of two distinct surface modification techniques on the clinical efficacy of titanium implants: A systematic review and meta-analysis
Wen, G., Zhang, Y., Xie, S., & Dong, W. (2024) · Journal of Stomatology Oral and Maxillofacial Surgery · doi:10.1016/j.jormas.2024.101855 · Cited by 6
Erythritol powder airflow for the treatment of peri‐implant mucositis: A randomized controlled clinical trial
Corbella, S., Radaelli, K., Alberti, A., Francetti, L. A., & Taschieri, S. (2024) · International Journal of Dental Hygiene · doi:10.1111/idh.12814 · Cited by 6
Dental Pathophysiology of Odontogenic Sinusitis
Alrmali, A., & Wang, H. (2024) · Otolaryngologic Clinics of North America · doi:10.1016/j.otc.2024.07.006 · Cited by 6
Self-citation
Antimicrobial and anti-biofilm activity of a mucoadhesive hydrogel functionalized with aminochalcone on titanium surfaces and in Galleria mellonella model: In vitro and in vivo study
Lima, F. R. R., de Figueiredo, L. C., Braga, A. R. O., Garcia, M. A. R., Carvalho, S. G., Regasini, L. O., Chorilli, M., & Sardi, J. D. C. O. (2025) · Microbial Pathogenesis · doi:10.1016/j.micpath.2025.107286 · Cited by 6
Photodynamic Therapy in Peri-implantitis: A Systematic Review of Efficacy, Safety, and Clinical Applications
Murthykumar, K., Choudhary, A., Suresh, N., Deliberador, T. M., Sasanka, L. K., & Sinduja, P. (2025) · World Journal of Dentistry · doi:10.5005/jp-journals-10015-2522 · Cited by 6
Long-term outcomes and risk assessment of immediate implants at molar extraction sites in a Taiwan population
Dung, S.-Z., Wang, J., Weng, T.-H., & Tu, Y. (2025) · Scientific Reports · doi:10.1038/s41598-025-06048-z · Cited by 6
The Submucosal Microbiome Correlates with Peri-implantitis Severity
Joshi, A. A., Szafrański, S. P., Steglich, M., Yang, I., Behrens, W., Schaefer-Dreyer, P., Grischke, J., Häußler, S., & Stiesch, M. (2025) · Journal of Dental Research · doi:10.1177/00220345251352809 · Cited by 6
Supportive Implant Therapy (SIT): A Prospective 10-Year Study of Patient Compliance Rates and Impacting Factors
Mitschke, J., Peikert, S. A., Vach, K., & Frisch, E. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9061988 · Cited by 6
Clinical considerations in the surgical management of peri‐implantitis lesions in the esthetic zone
Monje, A., & Mesquita, P. F. (2022) · Journal of Esthetic and Restorative Dentistry · doi:10.1111/jerd.12921 · Cited by 6
Self-citation
Customized root-analogue dental implants - Procedure and errors associated with image acquisition, treatment, and manufacturing technology in an experimental study on a cadaver dog mandible
Dantas, T., Rodrigues, F., Araújo, J. H. M. D. M., Vaz, P., & Silva, F. S. (2022) · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials · doi:10.1016/j.jmbbm.2022.105350 · Cited by 6
Antimicrobial surface treatment of titanium dental implants: a narrative review between 2011 and 2021
Jensen, O. T., Weiss, E. I., & Tarnow, D. P. (2022) · Frontiers of Oral and Maxillofacial Medicine · doi:10.21037/fomm-21-62 · Cited by 6
Clinical evaluation of narrow‐diameter implants versus standard‐diameter implants with lateral bone augmentation in posterior jaws: Three‐year results of a randomized controlled trial
Zhang, X., Liu, B., Qian, S., Shi, J., Zhang, X., & Lai, H. (2022) · Clinical Oral Implants Research · doi:10.1111/clr.14006 · Cited by 6
Association between Osteoprotegerin rs2073618 polymorphism and peri-implantitis susceptibility: a meta-analysis
Xu, M., Zhang, C., Han, Y., Yue, Z., Shu, C., & Hou, J. (2022) · BMC Oral Health · doi:10.1186/s12903-022-02657-6 · Cited by 6
Periimplantitis: conceptos actuales sobre su etiología, características clínicas e imagenológicas. Una revisión
Martínez, J. C., Hernández‐Andara, A., Quevedo-Piña, M., Ortega-Pertuz, A. I., & Chong, M. L. (2022) · Revista Científica Odontológica · doi:10.21142/2523-2754-1004-2022-134 · Cited by 6
Underdiagnosis in Background of Emerging Public Health Challenges Related to Peri-Implant Diseases: An Interventional Split-Mouth Study
Djuran, B., Tatić, Z., Perunović, N., Pejčić, N., Vuković, J., Petković-Ćurčin, A., Vojvodić, D., & Rakić, M. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20010477 · Cited by 6
Clinical, microbiological and biochemical impact of a supportive care protocol with an air‐polishing device, after surgical treatment of peri‐implantitis: Randomized clinical trial
Luengo, F., Sanz, J., Sanz‐Sánchez, I., Solonko, M., Herrera, D., & Sanz, M. (2023) · Clinical Oral Implants Research · doi:10.1111/clr.14049 · Cited by 6
Up to a 15-Year Survival Rate and Marginal Bone Resorption of 1780 Implants with or without Microthreads: A Multi Center Retrospective Study
Oh, J., Pyo, S.-W., Chang, J., & Kim, S. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12062425 · Cited by 6
Calcium phosphate cement with minocycline hydrochloride-loaded gelatine microspheres for peri-implantitis treatment
Liu, N., Huang, S., Guo, F., Wang, D., Zuo, Y., Li, F., & Liu, C. (2023) · Journal of Dentistry · doi:10.1016/j.jdent.2023.104624 · Cited by 6
The Role of Radiographic Imaging in the Diagnosis and Management of Periodontal and Peri-Implant Diseases
Ismail, A., & Yafi, F. A. (2023) · Dental Clinics of North America · doi:10.1016/j.cden.2023.09.002 · Cited by 6
Awareness of peri-implantitis among general dental practitioners in the UK: a questionnaire study
Thomas, S., & Barrak, F. (2024) · BDJ · doi:10.1038/s41415-024-7136-y · Cited by 6
Assessment of the Effect on Periodontitis of Antibiotic Therapy and Bacterial Lysate Treatment
Ancuța, D.-L., Alexandru, D. M., Муселин, Ф., Cristina, R. T., & Coman, C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25105432 · Cited by 10
Zirconia Dental Implants Surface Electric Stimulation Impact on Staphylococcus aureus
Rodrigues, F., Pereira, H., Pinto, J., Padrão, J., Zille, A., Silva, F. S., Carvalho, Ó. S. N., & Madeira, S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25115719 · Cited by 6
Surgical treatment with dental implants in a patient with secondary loss of teeth and osteoporosis caused by an imbalance of vitamin D
Diachkova, E. Y., Abramova, E. V., Blagushina, N., & Tarasenko, S. V. (2020) · BMJ Case Reports · doi:10.1136/bcr-2020-235585 · Cited by 6
Experimental peri-implantitis around titanium implants with a chemically modified surface with a monolayer of multi-phosphonate molecules: a preclinical in vivo investigation
Sanz, J., Raimondo, R. D., Plá, R., Luengo, F., Vignoletti, F., Núñez, J., Antonoglou, G. J., Blanco, J., & Sanz, M. (2021) · Clinical Oral Investigations · doi:10.1007/s00784-020-03708-4 · Cited by 6
Peri‐Implant Tissue Adaptation after Implant Rehabilitation with Shoulderless Abutments with 24 Months of Follow‐Up
Casula, L., Gillone, A., & Musu, D. (2021) · Case Reports in Dentistry · doi:10.1155/2021/6689446 · Cited by 6
Peri‐implant radiographic bone level and associated factors in Spain
Carral, C., Flores‐Guillén, J., Figuero, E., Rodrigo, D., Sanz‐Sánchez, I., Llodrá, J. C., Bravo, M., Caffesse, R. G., Vallcorba, N., Guerrero, A., et al. (2021) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.13437 · Cited by 6
Assessment of salivary alpha amylase and mucin-4 before and after non-surgical treatment of peri-implant mucositis
Aldulaijan, H. A., Al-Zawawi, A. S., Shaheen, M. Y., Ali, D. A., Divakar, D. D., & Basudan, A. M. (2022) · International Journal of Implant Dentistry · doi:10.1186/s40729-022-00429-z · Cited by 6
Bone construction surgery: A case report using recombinant human platelet‐derived growth factor‐BB
Mandelaris, G. A., & DeGroot, B. S. (2022) · Clinical Advances in Periodontics · doi:10.1002/cap.10220 · Cited by 6
How Porphyromonas gingivalis Navigate the Map: The Effect of Surface Topography on the Adhesion of Porphyromonas gingivalis on Biomaterials
Ardhani, R., Diana, R., & Pidhatika, B. (2022) · Materials · doi:10.3390/ma15144988 · Cited by 6
Peri‐implant inflammation increases the risk of osteonecrosis in mice treated with bisphosphonate
Bujila, A., Silva, D. N. D. A., Monajemzadeh, S., da Silveira, T. M., Elzakra, N., Casarin, M., Flores, K., Magyar, C. E., Marchesan, J. T., Kim, R. H., et al. (2025) · Journal of Periodontology · doi:10.1002/jper.24-0760 · Cited by 6
Clinical and Radiographic Performance of Two Distinct Sandblasted, Large‐Grit, Acid‐Etched Implant Surfaces: A Split‐Mouth Randomized Clinical Trial
Vílchez, B., Caneiro, L., Lima, C., Sanz‐Sánchez, I., Montero, E., Figuero, E., Blanco, J., & Sanz, M. (2025) · Clinical Oral Implants Research · doi:10.1111/clr.70071 · Cited by 5
Influence of dental implant surfaces on oral biofilms and host immune response
Vernon, J. J., Raïf, E. M., Aw, J., Attenborough, E., Jha, A., & Do, T. (2025) · Journal of Oral Microbiology · doi:10.1080/20002297.2025.2607199 · Cited by 5
Health economic potential of oral aMMP-8 biomarker diagnostics for personalised prevention of periodontal and peri-implant diseases
Frankenberger, R., Arweiler, N. B., Sorsa, T. A., Volland, G., Gaßmann, G., Fietz, C., Thiem, H., & Rychlik, R. P. T. (2022) · Journal of Pharmaceutical Health Services Research · doi:10.1093/jphsr/rmac008 · Cited by 5
Depth of mucosal tunnel in peri‐implant health during 12‐month follow‐up in patients with controlled periodontitis
Lin, C., Kuo, P., Chiu, M., & Wang, H. (2022) · Journal of Periodontology · doi:10.1002/jper.21-0680 · Cited by 5
Self-citation
Impact of Peri-Implant Inflammation on Metabolic Syndrome Factors: A Systematic Review
Zhang, Y., Lu, E. M., Moyes, D. L., & Niazi, S. A. (2023) · Applied Sciences · doi:10.3390/app132111747 · Cited by 5
Improved osseointegration of dental titanium implants by TiO 2 nanotube arrays with self-assembled recombinant IGF-1 in type 2 diabetes mellitus rat model
Zhang, Q., Wang, J., Xue, Q., Wang, Y., Zhang, M., & Chen, Y. (2023) · Nanotechnology Reviews · doi:10.1515/ntrev-2023-0120 · Cited by 5
Evaluation of implants in smoking and non-smoking patients with peri-implant disease risk analysis and esthetic scores: an observational study
Şahin, T. (2023) · BMC Oral Health · doi:10.1186/s12903-023-03696-3 · Cited by 5
Evaluation of peri-implant bone defects on cone-beam computed tomography and the diagnostic accuracy of detecting these defects on panoramic images
Oshima, T., Asaumi, R., Ogura, S., & Kawai, T. (2024) · Imaging Science in Dentistry · doi:10.5624/isd.20230258 · Cited by 5
Periodontists and oral surgeons’ peri‐implantitis‐related education, knowledge, attitudes, and professional behavior: A national survey
Polymeri, A., Marti, K. C., Aronovich, S., & Inglehart, M. R. (2024) · Journal of Dental Education · doi:10.1002/jdd.13547 · Cited by 5
Silk fibroin microgrooved zirconia surfaces improve connective tissue sealing through mediating glycolysis of fibroblasts
Yan, Y., Yan, Q., Cai, K., Wang, Z., Li, Q., Zhao, K., Jian, Y., & Jia, X. (2024) · Materials Today Bio · doi:10.1016/j.mtbio.2024.101158 · Cited by 5
Influence of gingival phenotype on crestal bone loss at implants
Breunig, N., Stiller, M., Mogk, M., & Mengel, R. (2024) · International Journal of Implant Dentistry · doi:10.1186/s40729-024-00531-4 · Cited by 5
Diabetes mellitus exacerbates inflammation in a murine model of ligature‐induced peri‐implantitis: A histological and microtomographic study
Silva, D. N. D. A., Monajemzadeh, S., Casarin, M., Chalmers, J. C., Lubben, J., Magyar, C. E., Tetradis, S., & Pirih, F. Q. M. (2024) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.14051 · Cited by 5
Assessment of risk factors and causes of inflammatory changes in the oral mucosa and bone tissue of the jaws surrounding dental implants
Ebrakhim, M., Моисеев, Д. А., Strelnikov, V., Цагараева, Т. Г., Salloum, A., Ogloblin, A. A., Abaev, Z. M., & Жукова, Н. А. (2024) · Operativnaâ hirurgiâ i kliničeskaâ anatomiâ (Pirogovskij naučnyj žurnal) · doi:10.17116/operhirurg2024803148 · Cited by 5
Management of Infected Tissues Around Dental Implants: A Short Narrative Review
Alghamdi, H. S., Leventis, M. D., & Deliberador, T. M. (2024) · Brazilian Dental Journal · doi:10.1590/0103-6440202406160 · Cited by 5
The Effect of Implantoplasty on Fracture Resistance and Implant Surface Changes: An In Vitro and Finite Element Analysis Study
Goh, R., Li, K. C., Atieh, M. A., Ma, S., Oliver, A., Giraldo, D. C., & Tawse‐Smith, A. (2024) · Clinical Implant Dentistry and Related Research · doi:10.1111/cid.13409 · Cited by 5
Methods for assessing peri-implant marginal bone levels on digital periapical radiographs: a meta-research
dos Reis, I. N. R., Vilela, N., Naenni, N., Jung, R. E., Schwarz, F., Romito, G. A., Spin‐Neto, R., & Pannuti, C. M. (2025) · Dentomaxillofacial Radiology · doi:10.1093/dmfr/twaf002 · Cited by 5
Self-citation
Long non-coding RNA NRIR inhibits osteogenesis in peri-implantitis by promoting NLRP3 inflammasome-mediated macrophage pyroptosis
Wang, L., Zhao, R., Xiao, K., Zhou, Y., Liu, Q., & Yu, K. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114180 · Cited by 6
Effect of solid abutment diameter and implant placement depth on stress distribution in the posterior mandible: A finite element analysis study
Ayres, G., Macedo, A. P., Kubata, B. R., & Múglia, V. A. (2025) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2025.109911 · Cited by 5
Association of MMP-8 -799C/T Polymorphism with Peri-Implantitis: A Cross-Sectional Study
Fragkioudakis, I., Kottaridi, C., Doufexi, A., Papadimitriou, K., Batas, L., & Sakellari, D. (2025) · Journal of Personalized Medicine · doi:10.3390/jpm15050182 · Cited by 5
Efficacy of photodynamic therapy with various photosensitizers for peri-implantitis treatment: a systematic review and meta-analysis of randomized clinical trials
Li, X., Liu, H., Yang, L., Ji, Y., Feng, D., Shao, R., Zhang, G., Lin, S., Duan, S., & Wu, X. (2025) · Lasers in Medical Science · doi:10.1007/s10103-025-04612-7 · Cited by 5
Implantoplasty vs. Rotating Titanium Brushes in the Surgical Treatment of Peri‐Implantitis: A 1‐Year Randomised Controlled Clinical Trial
Park, S., Kim, D., Kim, D., Sanz‐Martín, I., Sanz‐Sánchez, I., Derks, J., & Cha, J. (2025) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.70056 · Cited by 5
Self-citation
Ultrastructural changes of smooth and rough titanium implant surfaces induced by metal and plastic periodontal probes
Folwaczny, M., Rudolf, T., Frasheri, I., & Betthäuser, M. (2020) · Clinical Oral Investigations · doi:10.1007/s00784-020-03341-1 · Cited by 5
Prevalence of peri‐implantitis in a sample of HIV ‐positive patients
Casula, L., Poli, A., Clemente, T., Artuso, G., Capparè, P., & Gherlone, E. F. (2021) · Clinical and Experimental Dental Research · doi:10.1002/cre2.469 · Cited by 5
Effect of photobiomodulation after non‐surgical mechanical debridement on cortisol levels in the peri‐implant sulcular fluid among patients with peri‐implant mucositis
Alhumaidan, A. A., Alali, Y. S., Ahmed, S. O., Vohra, F. A., & Abduljabbar, T. S. (2022) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/phpp.12774 · Cited by 5
Longitudinal study on the effect of keratinized mucosal augmentation surrounding dental implants in preventing peri-implant bone loss
Kikuchi, T., Wada, M., Mameno, T., Hasegawa, D., Serino, G., & Ikebe, K. (2022) · PeerJ · doi:10.7717/peerj.13598 · Cited by 5
Retrospective Study of the Association between Peri-Implantitis and Keratinized Mucosa
Fons‐Badal, C., Labaig-Rueda, C., Agustín‐Panadero, R., Ruiz, M. F. S., Roig-Vanaclocha, A., Fernández‐Estevan, L., & Fons‐Font, A. (2022) · Applied Sciences · doi:10.3390/app12146980 · Cited by 5
Association of Peri-Implant Health Status With COVID-19
AlAhmari, F., Preethanath, R. S., Divakar, D. D., & Ali, D. A. (2022) · International Dental Journal · doi:10.1016/j.identj.2022.11.019 · Cited by 5
Effects of Candidalysin Derived from Candida albicans on the Expression of Pro-Inflammatory Mediators in Human Gingival Fibroblasts
Nishikawa, Y., Tomotake, Y., Kawano, H., Naruishi, K., Kido, J., Hiroshima, Y., Murakami, A., Ichikawa, T., & Yumoto, H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043256 · Cited by 5
Effectiveness of modified and control protocols for the surgical therapy of combined peri‐implantitis‐related defects. A retrospective analysis
Schwarz, F., Becker, K., Albrecht, C., Ramanauskaitė, A., Begić, A., & Obreja, K. (2023) · Clinical Oral Implants Research · doi:10.1111/clr.14057 · Cited by 5
Self-citation
Evaluation of IL-4, MIP-1α, and MMP-9 gene expression levels in peri-implant tissues in peri-implantitis
Giro, G., Taira, J., Andriani, F., Watinaga, S. E., Bastos, M. F., & Shibli, J. A. (2023) · Brazilian Dental Journal · doi:10.1590/0103-6440202305382 · Cited by 5
CREB3L2 Regulates Hemidesmosome Formation during Epithelial Sealing
Li, Y., Zhang, J., Cai, W., Wang, C., Yu, Z., Jiang, Z., Lai, K., Wang, Y., & Yang, G. (2023) · Journal of Dental Research · doi:10.1177/00220345231176520 · Cited by 5
An antibacterial conjugate of carbon nanohorns for NIR-light mediated peri-implantitis treatment
Hirata, E., Takano, Y., Konishi, D., Maeda, Y., Ushijima, N., Yudasaka, M., & Yokoyama, A. (2023) · Chemical Communications · doi:10.1039/d3cc03128d · Cited by 5
Microscopic in‐situ analysis of the mucosal healing around implants treated by protease activated receptor 4‐agonist peptide or perpendicularly protruded type I collagen in rats
Song, Y. W., Maekawa, S., Sasaki, K., Yoshida, D., Nagai, M., Ishikawa‐Nagai, S., Silva, J. D. D., Kim, D. M., & Chen, C. (2023) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.35330 · Cited by 5
Effects of adjacent periodontitis on osseointegrated dental implants
Ryoo, K.-S., Kim, K.-H., Cho, Y., Seol, Y., & Ku, Y. (2023) · Journal of Periodontal & Implant Science · doi:10.5051/jpis.2302400120 · Cited by 5
Evaluation of the effect of diode laser application on the hydrophilicity, surface topography, and chemical composition of titanium dental implant surface
Rezeka, M. A., Metwally, N. A., Rehim, S. S. A. E., & Khamis, M. M. (2024) · Journal of Prosthodontics · doi:10.1111/jopr.13823 · Cited by 5
Diagnostic potential of endothelin-1 in peri-implant diseases: a cross-sectional study
Saito, Y., Nodai, T., Munemasa, T., Mukaibo, T., Kondo, Y., Masaki, C., & Hosokawa, R. (2024) · International Journal of Implant Dentistry · doi:10.1186/s40729-024-00551-0 · Cited by 5
Production and characterization of the lipopeptide with anti-adhesion for oral biofilm on the surface of titanium for dental implants
Carvalho, F. S., Tarabal, V. S., Lívio, D. F., da Cruz, L. F., Monteiro, A. P. F., Parreira, A. G., Guimarães, P. P. G., Scheuermann, K., Chagas, R. C. R., da Silva, J. A., et al. (2024) · Archives of Microbiology · doi:10.1007/s00203-024-04078-1 · Cited by 5
Antimicrobial efficiency and cytocompatibility of resveratrol and naringin as chemical decontaminants on SLA surface
Zhou, Y., Shen, Z., Xu, Y., Qian, X., Chen, W., & Qiu, J. (2024) · Microbiology Spectrum · doi:10.1128/spectrum.03679-23 · Cited by 5
Nicotine promotes pathogenic bacterial growth and biofilm formation in peri-implant
Hu, R., Qian, H., Wang, X., Peng, B., & Huang, D. (2024) · Journal of Medical Microbiology · doi:10.1099/jmm.0.001897 · Cited by 5
Quantitative assessment of Candida albicans, Staphylococcus aureus and Staphylococcus epidermidis in peri-implant health and disease: correlation with clinical parameters
Fragkioudakis, I., Konstantopoulos, G., Kottaridi, C., Doufexi, A., & Sakellari, D. (2024) · Journal of Medical Microbiology · doi:10.1099/jmm.0.001933 · Cited by 5
Amorphous Magnesium Coating for Achieving Functional Changes from Antibacterial to Osteogenic Activities
Miyake, R., Shimabukuro, M., Terauchi, M., Marukawa, E., & Kawashita, M. (2024) · ACS Applied Bio Materials · doi:10.1021/acsabm.4c01341 · Cited by 5
Classic Publications in the Field of Dentistry: A Bibliometric Analysis
Ho, Y., & Christidis, N. (2025) · International Dental Journal · doi:10.1016/j.identj.2025.100909 · Cited by 5

Authors: Schwarz, F., Derks, J., Monje, A., & Wang, H.
Affiliations: Goethe University Frankfurt (DE)
University of Gothenburg (SE)
University of Bern (CH)
University of Michigan (US)
Corresponding author: Schwarz, Frank
ORCID: Schwarz, Frank
Monje, Alberto
Wang, Hom‐Lay
Venue: Journal of Clinical Periodontology
Publisher: Wiley
Published: 2018-06
Volume: 45
Issue: S20
Pages: S246-S266
ISSN: 0303-6979 (ISSN-L)
1600-051X
DOI: 10.1111/jcpe.12954
OpenAlex: W4211043384
Cited by: 1,066
References: 166
Citations by year: 2026: 130 · 2025: 139 · 2024: 186 · 2023: 179 · 2022: 159 · 2021: 116 · 2020: 108 · 2019: 39 · 2018: 7
FWCI: 13.00
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 19 d)
Locations: Journal Of Clinical Periodontology (publishedVersion)
PubMed (publishedVersion)
Deep Blue (University of Michigan) (submittedVersion)
Funders: Oral Reconstruction Foundation
Topics: Health Sciences › Dentistry › Oral Surgery › Dental Implant Techniques and Outcomes
Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
Health Sciences › Dentistry › Periodontics › Periodontal Regeneration and Treatments
Keywords: peri-implantitis, peri-implant mucositis, dental implants, marginal bone loss, disease progression, risk factors, chronic periodontitis, plaque control, smoking, diabetes mellitus, keratinized mucosa, probing depth, histopathology, peri-implant maintenance
MeSH terms: Dental Plaque, Humans, Oral Hygiene, Stomatitis, Dental Implants, Peri-Implantitis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Peri‐implantitis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks