Cited by 1,066Dental Implant Techniques and OutcomesOral microbiology and periodontitis researchPeriodontal Regeneration and Treatments

The DOI matches its Crossref record; 165 of the 166 references it cites were found in a registry or an index.

Peri‐implantitis

Open access

Schwarz, Frank, Derks, Jan, Monje, Alberto, Wang, Hom‐Lay·2018·Journal of Clinical Periodontology

DOI 10.1111/jcpe.12954

Open this paper in CoChat — free account Open PDF

Abstract

Objectives: This narrative review provides an evidence‐based overview on peri‐implantitis for the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions. Methods: A literature review was conducted addressing the following topics: 1) definition of peri‐implantitis; 2) conversion from peri‐implant mucositis to peri‐implantitis, 3) onset and pattern of disease progression, 4) characteristics of peri‐implantitis, 5) risk factors/indicators for peri‐implantitis, and 6) progressive crestal bone loss in the absence of soft tissue inflammation. Conclusions: Peri‐implantitis is a pathological condition occurring in tissues around dental implants, characterized by inflammation in the peri‐implant connective tissue and progressive loss of supporting bone. The histopathologic and clinical conditions leading to the conversion from peri‐implant mucositis to peri‐implantitis are not completely understood. The onset of peri‐implantitis may occur early during follow‐up and the disease progresses in a non‐linear and accelerating pattern. Peri‐implantitis sites exhibit clinical signs of inflammation and increased probing depths compared to baseline measurements. At the histologic level, compared to periodontitis sites, peri‐implantitis sites often have larger inflammatory lesions. Surgical entry at peri‐implantitis sites often reveals a circumferential pattern of bone loss. There is strong evidence that there is an increased risk of developing peri‐implantitis in patients who have a history of chronic periodontitis, poor plaque control skills, and no regular maintenance care after implant therapy. Data identifying “smoking” and “diabetes” as potential risk factors/indicators for peri‐implantitis are inconclusive. There is some limited evidence linking peri‐implantitis to other factors such as: post‐restorative presence of submucosal cement, lack of peri‐implant keratinized mucosa and positioning of implants that make it difficult to perform oral hygiene and maintenance. Evidence suggests that progressive crestal bone loss around implants in the absence of clinical signs of soft tissue inflammation is a rare event.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1111/jcpe.12954

Cites

165 of 165 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Global estimates of the prevalence of diabetes for 2010 and 2030
Shaw, J. E., Sicree, R. A., & Zimmet, P. Z. (2010) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2009.10.007 · Cited by 7,216
Global Burden of Severe Periodontitis in 1990-2010: A Systematic Review and Meta-regression
Kassebaum, N. J., Bernabé, E., Dahiya, M., Bhandari, B., Murray, C. J. L., & Marcenes, W. (2014) · Journal of Dental Research · doi:10.1177/0022034514552491 · Cited by 2,209
Peri‐implant diseases: Consensus Report of the Sixth European Workshop on Periodontology
Lindhe, J., Meyle, J., & on behalf of Group D of the European Workshop on Periodontology (2008) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.2008.01283.x · Cited by 1,524
Update on Prevalence of Periodontitis in Adults in the United States: NHANES 2009 – 2012
Eke, P., Dye, B., Wei, L., Slade, G., Thornton-Evans, G., Borgnakke, W., Taylor, G., Page, R., Beck, J., & Genco, R. (2015) · The Journal of Periodontology · doi:10.1902/jop.2015.140520 · Cited by 1,442
Risk factors for periodontal disease
Genco, R. J., & Borgnakke, W. S. (2013) · Periodontology 2000 · doi:10.1111/j.1600-0757.2012.00457.x · Cited by 1,307
Smoking‐Attributable Periodontitis in the United States: Findings From NHANES III
Tomar, S. L., & Asma, S. (2000) · Journal of Periodontology · doi:10.1902/jop.2000.71.5.743 · Cited by 1,002
Periimplant diseases: where are we now?--Consensus of the Seventh European Workshop on Periodontology
Lang, N. P., Berglundh, T., & on Behalf of Working Group 4 of the Seventh European Workshop on Periodontology (2011) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.2010.01674.x · Cited by 930
The long‐term effect of a plaque control program on tooth mortality, caries and periodontal disease in adults
Axelsson, P., Nyström, B., & Lindhe, J. (2004) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.2004.00563.x · Cited by 902
A prospective 15‐year follow‐up study of mandibular fixed prostheses supported by osseointegrated implants. Clinical results and marginal bone loss.
Lindquist, L. W., Carlsson, G. E., & Jemt, T. (1996) · Clinical Oral Implants Research · doi:10.1034/j.1600-0501.1996.070405.x · Cited by 700
Experimental breakdown of peri‐implant and periodontal tissues. A study in the beagle dog
Lindhe, J., Berglundh, T., Ericsson, I., Liljenberg, B., & Marinello, C. P. (1992) · Clinical Oral Implants Research · doi:10.1034/j.1600-0501.1992.030102.x · Cited by 667

Show all 166 references

Research works printed but not linked: 1

Hanselaer L, 2010, De Bruyn H. [Giant cell peripheral granuloma surrounding a dental implant: case report], Revue Belge de Medicine Dentaire (1984), 65, 152

Sorted by citations

Items 701–800 of 1,002

The use of a new chemical device based on silver and cationic surfactants as a new approach for daily oral hygiene: A preliminary study on a group of periodontal patients
Lauritano, D., Palmieri, A., D’Orto, O., Bolzoni, A. R., Ottria, L., GARGARI, M., Girolamo, M. D., & Candotto, V. (2019) · International Journal of Immunopathology and Pharmacology · doi:10.1177/2058738419868101 · Cited by 3
Development of a Novel Medical Device for Mucositis and Peri-Implantitis Treatment
Cosoli, G., Scalise, L., Leo, A. D., Russo, P., Tricarico, G., Tomasini, E. P., & Cerri, G. (2020) · Bioengineering · doi:10.3390/bioengineering7030087 · Cited by 3
Pilot Study of Use of Nitric Oxide in Monitoring Multiple Dental Foci in Oral Cavity—A Case Report
Wyszyńska, M., Rosak, P., Czelakowska, A., Białożyt-Bujak, E., Kasperski, J., Łopaciński, M., Khatib, N. A., & Skucha-Nowak, M. (2022) · Healthcare · doi:10.3390/healthcare10020195 · Cited by 3
Prevalence of bone loss surrounding dental implants as detected in cone beam computed tomography: a cross-sectional study
Algahtani, F. N., Hebbal, M. I., Alqarni, M. M., Alaamer, R., Alqahtani, A., Almohareb, R. A., Barakat, R. M., & Abdelhafeez, M. M. (2023) · PeerJ · doi:10.7717/peerj.15770 · Cited by 3
Resolution of peri‐implant mucositis following standard treatment: A prospective split‐mouth study
Rakić, M., Tatić, Z., Radovanović, S., Petković-Ćurčin, A., Vojvodić, D., & Monje, A. (2023) · Journal of Periodontology · doi:10.1002/jper.23-0507 · Cited by 3
Self-citation
Novel biopolymer spray formulation for drug delivery in precision dentistry
Tatullo, M., Marrelli, B., Facente, A., Paduano, F., & Qutachi, O. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e36038 · Cited by 3
НОВАЯ МЕЖДУНАРОДНАЯ КЛАССИФИКАЦИЯ ЗАБОЛЕВАНИЙ ПАРОДОНТА И ОКОЛОИМПЛАНТАТНЫХ ТКАНЕЙ
Əhmədbəyli, C. R., Mammadov, F. Y., Qarayev, R. M., Məmmədov, A. M., & Quliyeva, V. E. (2020) · Azerbajdžanskij medicinskij žurnal · doi:10.34921/amj.2020.2.015 · Cited by 3
The Merit to Phenotypic Modification Treatment for Dental Implants: Two Case Reports
Rosen, P. S. (2020) · Clinical Advances in Periodontics · doi:10.1002/cap.10106 · Cited by 3
Retrospective Clinicopathological Analysis of 65 Peri-Implant Lesions
Shuster, A., Frenkel, G., Kleinman, S., Peleg, O., Ianculovici, C., Mijiritsky, E., & Kaplan, I. (2021) · Medicina · doi:10.3390/medicina57101069 · Cited by 3
The use of autologous bone for augmentation procedures leads to low prevalence of peri-implantitis–a retrospective study over a 20-year period
Carls, F. P., Bernasconi, M., Carinci, F., Lawrence, M., & Lambrecht, J. T. (2023) · Journal of Cranio-Maxillofacial Surgery · doi:10.1016/j.jcms.2022.12.004 · Cited by 3
Proper Oral Hygiene Measures to Maintain Healthy Soft Tissues Around Dental Implants
Kim, I., Lin, K. C., & Kim, S. W. (2023) · Springer eBooks · doi:10.1007/978-3-031-45516-2_5 · Cited by 2
Deciphering peri-implantitis: Unraveling signature genes and immune cell associations through bioinformatics and machine learning
Cao, N., Wan, Z., Chen, D., & Tang, L. (2024) · Medicine · doi:10.1097/md.0000000000037862 · Cited by 2
KL‐12 Peptide Targets Peri‐Implantitis via Dual Antibacterial and Immunomodulatory Effects
Qin, J., Yang, S., Meng, W., Zhou, Z., Yu, Z., & Zhang, X. (2025) · Oral Diseases · doi:10.1111/odi.15401 · Cited by 2
UK implementation of 'treatment of stage IV periodontitis: The EFP S3-level clinical practice guideline’–rehabilitation of severe periodontitis patients
Kebschull, M., Chapple, I., D’Aiuto, F., Donos, N., Fleming, P. S., Jerreat, M. P., McCracken, G., Needleman, I. G., Nibali, L., & West, N. X. (2025) · Journal of Dentistry · doi:10.1016/j.jdent.2025.105847 · Cited by 2
Epigenetic factors associated with peri-implantitis: a review
Li, Q.-H., Lu, H., Zhang, M., Ye, Y. J., Chen, Q., & Sun, P. (2025) · Journal of Zhejiang University SCIENCE B · doi:10.1631/jzus.b2400032 · Cited by 2
Correlation between pre-extraction periodontal diagnosis and peri-implant microbiome for patients treated with implant-retained overdenture – A retrospective cohort pilot study
Cui, X., Luna, A. A. M., Gillone, A., Wu, Q., Serag, M., & Murata, R. M. (2025) · PLoS ONE · doi:10.1371/journal.pone.0325711 · Cited by 2
Reassessing the Use of Membranes in Peri-Implantitis Surgery: A Systematic Review and Meta-Analysis of In Vivo Studies
Cho, Y. J., Jeong, Y. T., Woo, H. N., Cho, H. W., Kang, M. G., Hwang, S., & Lee, J. (2025) · Journal of Functional Biomaterials · doi:10.3390/jfb16070262 · Cited by 2
Biofilm development of Porphyromonas gingivalis on titanium surfaces in response to 1,4-dihydroxy-2-naphthoic acid—a hybrid in vitro – in silico approach
Mukherjee, R., Klempt, F., Fuchs, F., Doll‐Nikutta, K., Soleimani, M., Wriggers, P., Junker, P., Stiesch, M., & Szafrański, S. P. (2025) · Microbiology Spectrum · doi:10.1128/spectrum.00410-25 · Cited by 2
Clinical Trends in the Prevention of Peri‐Implantitis: Spanish Society of Periodontology ( SEPA) Foundation Survey Using the Delphi Method
Monje, A., Molina, A., Lorenzo, O. A., de Tapia, B., Derks, J., Figuero, E., Guerrero, A., Luengo, F., Montero, E., Sanz‐Martín, I., et al. (2025) · Clinical Oral Implants Research · doi:10.1111/clr.70030 · Cited by 2
Self-citation
Mechanisms of Osteoblast‐Like Cells and Bacterial Responses to Copper in Titanium‐Copper Alloys
Khalid, J., Stephen, A. S., Rawlinson, S. C. F., & Allaker, R. P. (2025) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.37991 · Cited by 2
Influence of Local and Systemic Antibiotics in Non-Surgical Peri-Implantitis Treatment: A Systematic Review and Meta-Analysis Update
Meném, M., Estácio, C., Mascarenhas, P., & Santos, A. (2025) · Applied Sciences · doi:10.3390/app152111422 · Cited by 2
Surface and Biocompatibility Outcomes of Chemical Decontamination in Peri-Implantitis Management
Meşter, A., Bran, S., Moldovan, M., Petean, I., Barbu–Tudoran, L., Saroşi, C., Piciu, A., & Ene, D. (2025) · Biomedicines · doi:10.3390/biomedicines13112748 · Cited by 2
Rescue Therapy With Quad Zygoma After Failure of Full‐Arch Implant Rehabilitation: A Retrospective Study With a Mean Follow‐Up of 8 Years
Fan, S., Zhou, W., Al‐Nawas, B., Valmaseda‐Castellón, E., & Davó, R. (2026) · Clinical Oral Implants Research · doi:10.1111/clr.70086 · Cited by 2
Results of the Assessment of the Antimicrobial Resistance Profile of Pathogenic Oral Microorganisms in Patients with Chronic Generalized Periodontitis at the Pre-Implantation Stage: A Single-Center Pilot Study
Гуменюк, В. О. (2026) · SUCHASNA STOMATOLOHIYA · doi:10.33295/1992-576x-2025-6-62 · Cited by 2
Development of Titanium‐Based Nanocomposites Incorporating Silver Nanoparticles: A Novel Approach for Antibacterial and Biocompatible Materials in Dental Implants
Hossain, N., Chowdhury, M. A., Islam, S., Hossen, M. Z., Rahman, M. A., Chowdhury, M. S., Showrov, S. B., Shariar, M. F., & Kumer, A. (2026) · ChemistrySelect · doi:10.1002/slct.202503747 · Cited by 2
Long-term evaluation of hard and soft tissues around transmucosal implants with a convergent neck: a 10-year cohort study
Prati, C., Spinelli, A., Lenzi, J., Gandolfi, M. G., Tarsitano, A., Badiali, G., & Zamparini, F. (2026) · Oral and Maxillofacial Surgery · doi:10.1007/s10006-026-01536-6 · Cited by 2
Risk Factors Associated With Peri‐Implant Marginal Bone Loss Among Japanese Patients Receiving Supportive Periodontal Therapy: A 10‐Year Retrospective Study
Hasegawa, D., Mameno, T., Wada, M., Nishimura, Y., Kikuchi, T., Onodera, Y., Serino, G., & Ikebe, K. (2026) · Clinical Oral Implants Research · doi:10.1111/clr.70114 · Cited by 2
Dental Implant Outcomes in Patients with Cleft Lip, Alveolus and/or Palate: A Systematic Analysis of Clinical Studies
Țenț, P. A., Meşter, A., Armencea, G., Bran, S., Sabau, D., Piciu, A., & Onisor, F. G. (2026) · Medicina · doi:10.3390/medicina62030569 · Cited by 2
Dental devices and antimicrobial resistance: challenges, innovations, and regulatory compliances
Singh, G., Singh, M., Murali, A., Gandhi, S., & Singh, O. V. (2026) · Frontiers in Medical Technology · doi:10.3389/fmedt.2026.1750006 · Cited by 2
Efficacy of Xanthan‐Based Chlorhexidine Gel in Peri‐Implant Mucositis Treatment: A Split‐Mouth Randomized Clinical Trial
Curcio, J. J., Lanzetti, J., Crupi, A., Ambrogio, G., Gibello, U., Roccuzzo, A., & Pera, F. (2026) · Clinical Implant Dentistry and Related Research · doi:10.1111/cid.70137 · Cited by 2
Keratinized Mucosa Width and Incidence of Peri‐Implant Diseases: A Systematic Review With Meta‐Analysis
dos Reis, I. N. R., Thoma, D. S., da Silva, T. E., Passos, M. Q., Feitosa, L. S., Pannuti, C. M., Jung, R. E., & Naenni, N. (2026) · Journal of Periodontal Research · doi:10.1111/jre.70123 · Cited by 2
Microswarm bridging effect for dual-surface biofilm eradication in submillimeter infection pockets
Du, H., Yang, S., Guo, J., Wang, X., Sun, B., Hao, B., Yang, H., Hou, X., Wang, Q., Su, L., et al. (2026) · Science Advances · doi:10.1126/sciadv.aeb9792 · Cited by 2
Next Generation Smart Implant Surfaces: Engineering Multifunctional Antimicrobial, Immunomodulatory and Regenerative Interfaces
Pessoa, R. S. [., Steele, L. E., Mumtaz, M., Linklater, D. P., O’brien-simpson, N. M., Baulin, V. A., Kingshott, P., Judge, R. B., Sloan, A. J., & Ivanova, E. P. (2026) · Journal of Periodontal Research · doi:10.1111/jre.70149 · Cited by 2
Immediate Post-Extraction Short Implant Placement with Immediate Loading and without Extraction of an Impacted Maxillary Canine: Two Case Reports
Rodríguez, J., Gironés, J. G., Rodríguez‐Lozano, F. J., & Pecci-Lloret, M. R. (2021) · Materials · doi:10.3390/ma14112757 · Cited by 2
Peri-implantitis: A Classification Update
Shrestha, R., & Bhochhibhoya, A. (2021) · Nepal Journal of Health Sciences · doi:10.3126/njhs.v1i2.42384 · Cited by 2
Peri-implantitis: A Review to Simplify a Mystifying Disease
Ismail, A., Shaddox, L. M., Santamaria, M. P., & Al‐Sabbagh, M. (2022) · Medical Research Archives · doi:10.18103/mra.v10i10.3201 · Cited by 2
SMOKING MAY BE STRONGLY ASSOCIATED WITH PERI‑IMPLANTITIS
Cheng, L. L. (2023) · Journal of Evidence Based Dental Practice · doi:10.1016/j.jebdp.2023.101913 · Cited by 2
Defining in vitro topical antimicrobial and antibiofilm activity of epoxy-tigliane structures against oral pathogens
Xue, W., Pritchard, M., Khan, S., Powell, L. C., Stokniene, J., Wu, J., Claydon, N., Reddell, P. W., Thomas, D. W., & Hill, K. E. (2023) · Journal of Oral Microbiology · doi:10.1080/20002297.2023.2241326 · Cited by 3
Three cases of gingival cancer associated with peri‐implantitis and their management
Osawa, K., Okamoto, Y., Iida, M., Hirota, M., & Mitsudo, K. (2024) · Oral Science International · doi:10.1002/osi2.1239 · Cited by 2
Cirugía de las comunicaciones buconasosinusales
Lehner, J., Gellée, T., Levy-Bohbot, A., Pomes, B., Goudot, P., & Bertolus, C. (2024) · EMC - Cirugía Otorrinolaringológica y Cervicofacial · doi:10.1016/s1635-2505(24)49034-8 · Cited by 2
Immunogenic effects of enamel matrix derivative on human alveolar ridge mucosa-derived vascular endothelial cells under lipopolysaccharide stimulation
Yaita, N., Maruyama, K., Hiroyasu, K., & Sato, S. (2024) · Odontology · doi:10.1007/s10266-024-00959-5 · Cited by 2
Effect of Implant Maintenance on Incidence of Peri-implantitis and Early Implant Failure: Retrospective Cohort Study
Deeb, J. G., Ha, M., Carrico, C. K., Waldrop, T. C., & Wojnarwsky, P. K. L. (2024) · Journal of Oral Implantology · doi:10.1563/aaid-joi-d-24-00003 · Cited by 2
A Study on Materials Used and Longevity of Implant-Supported Prostheses
Perti, S., Singh, R., Choithani, K. K., Duseja, S., Mitthra, S., Dewan, H., & Tiwari, R. (2024) · Journal of Pharmacy And Bioallied Sciences · doi:10.4103/jpbs.jpbs_274_24 · Cited by 2
Risk Indicators of Peri‐Implant Diseases in Public and Private Clinics: A Multicenter Study
Kadkhodazadeh, M., Amid, R., Amirinasab, O., Amirbandeh, O., & Moscowchi, A. (2024) · International Journal of Dentistry · doi:10.1155/2024/7061682 · Cited by 2
Clinical outcomes and supragingival microbiota analysis around dental implants and teeth in patients with a history of periodontitis: a preliminary study of 6 months follow-up
Sim, N. C. W., Al‐Maleki, A. R., Sulaiman, E., Hassan, N. H. M., & Safii, S. H. (2024) · Clinical Oral Investigations · doi:10.1007/s00784-024-05922-w · Cited by 2
Antimicrobial Peptides Targeting Oral Pathogens: Applicability as an Oral Disease Treatment and Dental Material
Im, S., Lee, J. H., & Shim, Y.-S. (2024) · Journal of dental hygiene science · doi:10.17135/jdhs.2024.24.4.231 · Cited by 2
A novel combined implantoplasty and regenerative surgical approach to salvage implants: A report on two 20-year-old implants
Dung, S.-Z. (2025) · Journal of Dental Sciences · doi:10.1016/j.jds.2025.04.003 · Cited by 2
Photosensitizers as potential culprits for compensatory benefits of aPDT in the treatment of peri‐implantitis: Unraveling the fundamental knowledge and bounded clinical applications of the aPDT
Santana, A. P., Mulinari‐Santos, G., Pereira, M. M. A., Cunha, D. M., Guerreiro, M. M., WAINWRIGHT, M. S., Theodoro, L. H., de Ávila, É. D., & Assunção, W. G. (2025) · Photochemistry and Photobiology · doi:10.1111/php.14120 · Cited by 2
Clinical case report: Immediate full‐arch implant placement and loading technique using a fiducial‐free dynamic navigation workflow
Kachlan, M. O., Mostoufi, B., Majeed‐Saidan, A., Kanikicharla, S., & Masri, R. M. (2025) · Journal of Prosthodontics · doi:10.1111/jopr.70010 · Cited by 2
Pulsed electromagnetic field therapy on nonsurgical treatment of peri‐implantitis: 12–26 months follow‐up
Mayer, Y., Gabay, E., Younis, A., Ginesin, O., Siroma, R. S., Barak, S., Georgy, I., Friedlander, Y., Asbi, T., Zigdon‐Giladi, H., et al. (2025) · Journal of Periodontology · doi:10.1002/jper.11384 · Cited by 2
SECONDARY ETIOLOGICAL FACTORS IN THE DEVELOPMENT OF PERI-IMPLANTITIS
Sabeva, E. (2021) · Journal of IMAB - Annual Proceeding (Scientific Papers) · doi:10.5272/jimab.2021272.3682 · Cited by 2
Achieving Predictable Esthetics With Early Implant Placement and Soft Tissue Modeling: A Case Report and Literature Review
Mhatre, S., Gupta, R., Vaz, M., Bijalani, D., Joshi, M., Gholap, P., Shetty, U., & Srichand, R. (2024) · Cureus · doi:10.7759/cureus.64549 · Cited by 2
Comparative study of polymeric nanoparticles and traditional agents in dental implant decontamination
Haugen, H. J., Bueno, J., Hussain, B., Osorio, R., & Sanz, M. (2025) · Journal of Applied Biomaterials & Functional Materials · doi:10.1177/22808000251313948 · Cited by 2
Dental Disease Association with Bacterial Biofilm
Aryah, U. S., Prasanth, N., Stani, R., Kandanattu, B., & George, N. (2025) · Springer eBooks · doi:10.1007/978-981-96-8975-0_6 · Cited by 3
Diabetes mellitus—Dental implants and periodontal disease
Yu, S., & Oh, T. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820605-8.00007-3 · Cited by 2
Peri-implant bone-level changes in the second decade of loading with regard to the implant–abutment connection: a retrospective study on implants under systematic aftercare
Kruse, A., Wild, V., Ratka‐Krüger, P., Vach, K., & Frisch, E. (2021) · International Journal of Implant Dentistry · doi:10.1186/s40729-021-00384-1 · Cited by 2
A novel histopathological classification of implant periapical lesion: A systematic review and treatment decision tree
Gong, J., Zhao, R., Yu, Z., Li, J., & Mei, M. (2022) · PLoS ONE · doi:10.1371/journal.pone.0277387 · Cited by 2
Dental Implant Treatment for Diabetic Patients
Wu, Y., Wang, Y., & Yuan, Q. (2019) · Springer eBooks · doi:10.1007/978-3-030-28557-9_6 · Cited by 2
Peri-implant disease part 1: diagnosis and assessment parameters
Daly, A., & McCracken, G. (2019) · Dental Update · doi:10.12968/denu.2019.46.10.978 · Cited by 2
Photodynamic therapy in peri-implantitis treatment: an integrative literature review
Oliveira, E. H. D. S., Sakamoto, M. Y., Pasquinelli, F., Roman‐Torres, C. V. G., & Filho, H. O. S. (2021) · Lasers in Dental Science · doi:10.1007/s41547-021-00124-z · Cited by 2
Peri-Implantitis Revisited
Shatta, A., & Anil, S. (2021) · Dentistry · doi:10.5772/intechopen.100293 · Cited by 2
Prevention and Management of Peri‐Implant Diseases
Aroca, S., Salvi, G. E., Roccuzzo, A., Renert, U., Sculean, A., & Artzi, Z. (2020) · Wiley eBooks · doi:10.1002/9781119427926.ch25 · Cited by 2
Clinical, Microbiological, and Immunological Risk Indicators of Peri‐implant Mucositis and Early Peri‐implant Bone Loss
Belibasakis, G. N., Manoil, D., Gürkan, A., & Bostancı, N. (2024) · Wiley eBooks · doi:10.1002/9781119807049.ch4 · Cited by 2
Metallic Nanoparticles as a Risk Factor for Peri‐implant Diseases
Pettersson, M., & Romanos, G. E. (2024) · Wiley eBooks · doi:10.1002/9781119807049.ch5 · Cited by 2
A Retrospective Study on the Factors Affecting the Early Marginal Bone Loss of Tissue-Level Implants
Koo, S.-M., Kang, D., Duong, H. P., Shin, H., & Park, J. (2021) · Journal of implantology and applied sciences · doi:10.32542/implantology.2021017 · Cited by 1
Development of reduced volume endosseous cuspid tooth implant using topology optimization by SIMP technique for improved osseointegration
Soni, P., Shrivastava, P., & Rai, S. K. (2023) · Computer Methods in Biomechanics & Biomedical Engineering · doi:10.1080/10255842.2023.2279939 · Cited by 1
Fibrin clot adherence on cleaned and decontaminated titanium abutment surfaces: An in vitro study
Ulusoy, H. Ö., Ercan, E., Özatik, O., & Tunalı, M. (2024) · Clinical Implant Dentistry and Related Research · doi:10.1111/cid.13366 · Cited by 1
The Effect of Patient-associated Factors on Long-Term Survival of Dental Implants
Callahan, N. F., Weyh, A., Ghunaim, D., & Miloro, M. (2024) · Oral and Maxillofacial Surgery Clinics of North America · doi:10.1016/j.coms.2024.09.001 · Cited by 1
Using Deep Learning Algorithms to Predict Dental Implant Brands from Panoramic Radiographs
Taşdemir, İ., İçen, V., & Kölüş, T. (2024) · Medical Records · doi:10.37990/medr.1524857 · Cited by 1
Identification of Alterations in the Expression of Genes Related to the Implant Failure in Spanish Patients with Down Syndrome and Periodontal Disease
Cortés-Eslava, D., Gómez-Díaz, R., Torrés-Lagares, D., Machuca‐Portillo, G., Pérez, J. L. G., Serrera‐Figallo, M., & Baus‐Domínguez, M. (2025) · Genes · doi:10.3390/genes16020122 · Cited by 1
Submental Abscess Following Peri-Implantitis: Case Report and Comprehensive Literature Review
D’Angeli, G., Arcuri, L., Carosi, P., VINCENTIIS, M. D., Testarelli, L., & Galli, M. (2025) · Applied Sciences · doi:10.3390/app15052398 · Cited by 1
Evaluation of the impact of periodontitis susceptibility on perI-implant marginal bone level changes: A longitudinal retrospective study
Ayyıldız, H., Eken, S., TERZİOĞLU, A. G., & Güler, B. (2025) · Journal of Dentistry · doi:10.1016/j.jdent.2025.105757 · Cited by 1
Evaluation of Knowledge, Attitudes, and Practices Regarding Dental Implant Maintenance among Dental Professionals: A Cross-Sectional Questionnaire Study
Mahajani, M., Bhatt, M., Laddha, R., Kharat, S., & Patel, M. S. (2025) · Journal of Pharmacy And Bioallied Sciences · doi:10.4103/jpbs.jpbs_700_25 · Cited by 1
YAG laser combined with mechanical debridement enhances pain relief and inflammation control in the management of periodontitis with peri-implantitis
Sun, D. (2025) · American Journal of Translational Research · doi:10.62347/viot6629 · Cited by 1
Risk factors for implant failure of implant-supported fixed full-arch rehabilitation in edentulous maxillae and mandibles: A 1- to 7-year retrospective study
Chen, Y., Pu, R., Xia, Z., Ke, Y., Wang, Y., Jiang, Z., & Yang, G. (2025) · Journal of Dentistry · doi:10.1016/j.jdent.2025.106146 · Cited by 1
Cell Accelerated Corrosion (CAC) on the Dental Implant: An Exploratory Study with Gingival Fibroblasts and Macrophages
Alhamad, M., Chen, Y., Kanniyappan, H., Paramsivan, M., George, A., Barão, V. A. R., Sukotjo, C., & Mathew, M. T. (2025) · Journal of Bio- and Tribo-Corrosion · doi:10.1007/s40735-025-01062-0 · Cited by 1
Antimicrobial‐Releasing Implant Substrates for Combating Oral Biofilms: An In Vitro Study
Kamarudin, N. H. N., Vanmunster, L., Hooreweder, B. V., Simoens, K., Bernaerts, K., Teughels, W., Braem, A., & Zayed, N. (2025) · Clinical Oral Implants Research · doi:10.1111/clr.70067 · Cited by 1
Biofilm removal capacity and titanium surface integrity in non‐abrasive versus abrasive peri‐implantitis cleaning interventions
Jazaeri, M. S., Siddiqui, D. A., Tsai, Y. C., Gabel, K., Lorenzana, Z., & Kotsakis, G. A. (2025) · Journal of Periodontology · doi:10.1002/jper.11371 · Cited by 1
Amoxicillin and metronidazole resistance of bacteria isolated from dental implants with peri-implant diseases: a pilot cross-sectional study
Secundino, I., Reséndiz-Jaramillo, C., Palacios-Castañon, Y., Pérez, N. Z., Santiago-Martínez, M. P., Zermeño-Loredo, M. T., Reyes-Martínez, J. E., & Nizet, V. (2026) · Access Microbiology · doi:10.1099/acmi.0.000946.v3 · Cited by 1
Peri‐Implant Diseases and Systemic Conditions: A Bibliometric and Visual Analysis Study on the Interconnections
Polizzi, A., Annunziata, M., Serra, S., Leonardi, R. M., Lombardi, T., & Isola, G. (2026) · International Journal of Dentistry · doi:10.1155/ijod/7982454 · Cited by 1
Clinical Prediction Models for Peri-Implantitis Through an Immunopathological Lens: A Systematic Review and Functional Meta-Synthesis of Machine Learning and Conventional Approaches
Ardila, C. M., Pineda‐Vélez, E., & Vivares‐Builes, A. M. (2026) · Immuno · doi:10.3390/immuno6010019 · Cited by 1
Biomarker-Guided Implant Maintenance (BGIM): A Narrative Review and Protocol Proposal
Testori, T., Lazzara, R. J., Guarnieri, R., & FABBRO, M. D. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15072496 · Cited by 1
The Efficacy of Three Combinatory Decontamination Protocols and BMP ‐2‐Incorporated BioCaP ‐Based Regenerative Material in Treating Implants With Peri‐Implantitis In Vivo
Wang, T., Shan, Y., Forouzanfar, T., Liang, J., Zhao, Z., Sun, P., Wu, G., & Lin, H. (2026) · Clinical Oral Implants Research · doi:10.1111/clr.70126 · Cited by 1
Highly Cited Dental Implant Research: A Bibliometric Analysis of Publication Patterns and Research Themes
Ho, Y., Grigoriadis, A., Christidis, N., & Grigoriadis, J. (2026) · Healthcare · doi:10.3390/healthcare14101301 · Cited by 1
Fatigue Behavior of Dental Implants Affected by Peri-Implantitis-Related Bone Loss: Influence of Implantoplasty Evaluated Through In Vitro Testing and Finite Element Modeling
Roig, E. P. I., Fonseca, D., Callejas-Cano, J. A., Delgado, L. M., López-Oliva, E., Aparicio, C., Velasco‐Ortega, E., & Gil, J. (2026) · Dentistry Journal · doi:10.3390/dj14060329 · Cited by 1
Mechanical Versus Laser Debridement of SLA Titanium Implants: An In Vitro Morphological and Elemental Analysis of Debris Removal and Surface Preservation
Yurdakul, B., Meyvaci, S., Aykol‐Sahin, G., Gokbuget, A. Y., Yalcin, F., & Başer, Ü. (2026) · Nanomaterials · doi:10.3390/nano16120703 · Cited by 1
Effect of probiotics on oral biofilm formation on titanium and SLA implant surfaces: An in vitro and in situ study
Takeda, T. T. S., Borges, M. H. R., Malheiros, S. S., Costa, R. C., Bertolini, M., NAGAY, B. E., Souza, J. G. S., & Barão, V. A. R. (2026) · Journal of Prosthetic Dentistry · doi:10.1016/j.prosdent.2026.05.032 · Cited by 1
Hyperglycemia and systemic inflammation differentially shape immune dysregulation, tissue destruction, and microbiota in experimental periodontitis and peri-implantitis in diabetic mice
Memida, T., Jaar, J. C., Chen, T., Cao, G., Kuriki, N., Abdolahinia, E. D., Okamoto, M., Shindo, S., Yamashita, S., He, X., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1847456 · Cited by 1
Peri‐Implant Soft Tissue Phenotype Remodeling Following Peri‐Implantitis Surgery: A Prospective Profilometric Analysis
Choi, H., Park, S., Stender, I. M., Kim, D.-M., Pang, E., Sanz‐Martín, I., & Cha, J. (2026) · Clinical Implant Dentistry and Related Research · doi:10.1111/cid.70181 · Cited by 1
Narrow diameter titanium–zirconium tissue‐level implants supporting multi‐unit FDPs in the anterior area: A 5‐year prospective study
Altuna, P., Villar, S. F., Barroso‐Panella, A., Ortiz‐Puigpelat, O., Hernández-Alfaro, F. J., & Nart, J. (2023) · Clinical Oral Implants Research · doi:10.1111/clr.14101 · Cited by 1
Combined surgical-orthodontic and prosthetic treatment of a partially edentulous patient with skeletal Class III malocclusion
Numazaki, K., Seiryu, M., Yamauchi, K., Yoda, N., Ito, A., & Mizoguchi, I. (2023) · Clinical and Investigative Orthodontics · doi:10.1080/27705781.2023.2235738 · Cited by 1
PREVALÊNCIA DAS DOENÇAS PERI-IMPLANTARES EM PACIENTES PORTADORES DE PRÓTESES TOTAIS FIXAS SOBRE IMPLANTES
do Nascimento, J. V. M., Novais, P. M. R., Barrio, R. A. L. D., Gouvea, C. S., Bezerra, T. P., Alcântara, A. P. S. D. L., do Nascimento, P. H. M., & Lima, D. L. F. (2024) · Brazilian Journal of Implantology and Health Sciences · doi:10.36557/2674-8169.2024v6n3p978-996 · Cited by 1
Evaluation of Bone Loss in Implants Adjacent to a Tooth or Edentulous Area in Peri-Implantitis and Control Murine Models
da Silveira, T. M., Silva, D. N. D. A., Casarin, M., Monajemzadeh, S., Chalmers, J. C., & Pirih, F. Q. M. (2024) · Journal of Oral Implantology · doi:10.1563/aaid-joi-d-24-00100 · Cited by 1
Potential Biomarkers Indicating Resistance or Resilience in Experimental Peri‐Implant Mucositis: A Systematic Review and Meta‐Analysis
Huamán‐Mendoza, A. A., do Amaral, G. C. L. S., Vilela, N., Chuquimez‐Ventura, C. V., Rovai, E. S., Romito, G. A., Pannuti, C. M., Villar, C. C., & Holzhausen, M. (2025) · Clinical Oral Implants Research · doi:10.1111/clr.14427 · Cited by 2
High-intensity focused ultrasound for biofilm debridement, an in vitro proof-of-concept using Ti-attached Streptococcus mutans
Tran, M. D., Rajan, S. M., Ngo, H. C., & Fawzy, A. (2025) · International Journal of Implant Dentistry · doi:10.1186/s40729-025-00645-3 · Cited by 1
Quantitative real-time PCR detection of Porphyromonas gingivalis and Filifactor alocis in peri-implantitis
Fragkioudakis, I., Konstantopoulos, G., Kottaridi, C., Batas, L., & Sakellari, D. (2025) · Journal of Medical Microbiology · doi:10.1099/jmm.0.002091 · Cited by 1
Cytocompatibility and Microbiological Effects of Ti6Al4V Particles Generated During Implantoplasty on Human Fibroblasts, Osteoblasts, and Multispecies Oral Biofilm
Vegas-Bustamante, E., Toledano‐Serrabona, J., Sánchez‐Garcés, M. Á., Figueiredo, R., Demiquels-Punzano, E., Gil, J., Delgado, L. M., Sanmartí-García, G., & Camps‐Font, O. (2025) · Materials · doi:10.3390/ma18245626 · Cited by 1
In Vitro Evaluation of Pore Size and Weight Changes of Elderberry-Enriched Carboxymethyl Chitosan in Various Biological Fluids
Saylan, B. C. U., Baysan, G., Yılmaz, O., Aktaş, S., & Havıtçıoğlu, H. (2025) · Journal of Materials and Mechatronics A · doi:10.55546/jmm.1717116 · Cited by 1
Drugs and polymer based local delivery systems in the treatment of periodontal diseases
Zafar, F., Sheraz, M. A., Ali, S. A., Ahmed, S., Anwar, Z., & Riaz, M. (2026) · Profiles of drug substances, excipients, and related methodology · doi:10.1016/bs.podrm.2025.12.006 · Cited by 1
The influence of implant platform apico‐coronal position on the bone level of adjacent teeth
Yeh, Y., Li, V. W. T., Chen, C. C., Chen, H., Lin, G., Kao, R. T., & Ioannidou, E. (2026) · Journal of Periodontology · doi:10.1002/jper.70056 · Cited by 1

Authors: Schwarz, F., Derks, J., Monje, A., & Wang, H.
Affiliations: Goethe University Frankfurt (DE)
University of Gothenburg (SE)
University of Bern (CH)
University of Michigan (US)
Corresponding author: Schwarz, Frank
ORCID: Schwarz, Frank
Monje, Alberto
Wang, Hom‐Lay
Venue: Journal of Clinical Periodontology
Publisher: Wiley
Published: 2018-06
Volume: 45
Issue: S20
Pages: S246-S266
ISSN: 0303-6979 (ISSN-L)
1600-051X
DOI: 10.1111/jcpe.12954
OpenAlex: W4211043384
Cited by: 1,066
References: 166
Citations by year: 2026: 130 · 2025: 139 · 2024: 186 · 2023: 179 · 2022: 159 · 2021: 116 · 2020: 108 · 2019: 39 · 2018: 7
FWCI: 13.00
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 19 d)
Locations: Journal Of Clinical Periodontology (publishedVersion)
PubMed (publishedVersion)
Deep Blue (University of Michigan) (submittedVersion)
Funders: Oral Reconstruction Foundation
Topics: Health Sciences › Dentistry › Oral Surgery › Dental Implant Techniques and Outcomes
Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
Health Sciences › Dentistry › Periodontics › Periodontal Regeneration and Treatments
Keywords: peri-implantitis, peri-implant mucositis, dental implants, marginal bone loss, disease progression, risk factors, chronic periodontitis, plaque control, smoking, diabetes mellitus, keratinized mucosa, probing depth, histopathology, peri-implant maintenance
MeSH terms: Dental Plaque, Humans, Oral Hygiene, Stomatitis, Dental Implants, Peri-Implantitis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Peri‐implantitis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks