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Management of Neuropsychiatric Symptoms of Dementia in Clinical Settings: Recommendations from a Multidisciplinary Expert Panel
Open accessAbstract
Noncognitive neuropsychiatric symptoms ( NPS ) of dementia (aggression, agitation, depression, anxiety, delusions, hallucinations, apathy, disinhibition) affect individuals with dementia nearly universally across dementia stages and etiologies. NPS are associated with poor outcomes for individuals with dementia and caregivers, including excess morbidity and mortality, greater healthcare use, and earlier nursing home placement, as well as caregiver stress, depression, and difficulty with employment. Although the F ood and D rug A dministration has not approved pharmacotherapy for NPS , psychotropic medications are frequently used to manage these symptoms, but in the few cases of proven pharmacological efficacy, significant risk of adverse effects may offset benefits. There is evidence of efficacy and limited potential for adverse effects of nonpharmacological treatments, typically considered first line, but their uptake as preferred treatments remains inadequate in real‐world clinical settings. Thus, the field currently finds itself in a predicament in terms of management of these difficult symptoms. It was in this context that the U niversity of M ichigan P rogram for P ositive A ging, working in collaboration with the J ohns H opkins A lzheimer's D isease R esearch C enter and C enter for I nnovative C are in A ging sponsored and convened a multidisciplinary expert panel in D etroit, M ichigan, in fall 2011 with three objectives: to define critical elements of care for NPS in dementia; to construct an approach describing the sequential and iterative steps of managing NPS in real‐world clinical settings that can be used as a basis for integrating nonpharmacological and pharmacological approaches; and to discuss how the approach generated could be implemented in research and clinical care.
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“Care home residents with agitation often find sitting still difficult and therefore might not be included in activities.217, 218”
From Dementia prevention, intervention, and care: 2020 report of the Lancet Commission (2020) · cites this paper as [217]
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Cites
Neuropsychiatric symptoms in Alzheimer's disease
Lyketsos, C. G., Carrillo, M. C., Ryan, J. M., Khachaturian, A. S., Trzepacz, P., Amatniek, J., Cedarbaum, J., Brashear, R., & Miller, D. S. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.05.2410 · Cited by 1,139
Self-citationPharmacological Treatment of Neuropsychiatric Symptoms of Dementia: A Review of the Evidence
Sink, K. M., Holden, K. F., & Yaffe, K. (2005) · JAMA · doi:10.1001/jama.293.5.596 · Cited by 910
Patient and Caregiver Characteristics and Nursing Home Placement in Patients With Dementia
Yaffe, K. (2002) · JAMA · doi:10.1001/jama.287.16.2090 · Cited by 903
Husebo, B. S., Ballard, C., Sandvik, R., Nilsen, O. B., & Aarsland, D. (2011) · BMJ · doi:10.1136/bmj.d4065 · Cited by 571
Predicting caregiver burden and depression in Alzheimer'sdisease
Clyburn, L. D., Stones, M. J., Hadjistavropoulos, T., & Tuokko, H. A. (2000) · The Journals of Gerontology Series B · doi:10.1093/geronb/55.1.s2 · Cited by 536
Nonpharmacologic Management of Behavioral Symptoms in Dementia
Gitlin, L. N., Kales, H. C., & Lyketsos, C. G. (2012) · JAMA · doi:10.1001/jama.2012.36918 · Cited by 495
Self-citationMeta-Analysis of Nonpharmacological Interventions for Neuropsychiatric Symptoms of Dementia
Brodaty, H., & Arasaratnam, C. (2012) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.11101529 · Cited by 479
Management of agitation and aggression associated with Alzheimer disease
Ballard, C. G., Gauthier, S., Cummings, J. L., Brodaty, H., Grossberg, G. T., Robert, P., & Lyketsos, C. G. (2009) · Nature Reviews Neurology · doi:10.1038/nrneurol.2009.39 · Cited by 404
Self-citationLyketsos, C. G., DelCampo, L., Steinberg, M., Miles, Q., Steele, C. D., Munro, C., Baker, A. S., Sheppard, J.-M. E., Frangakis, C., Brandt, J., et al. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.7.737 · Cited by 398
Self-citationManagement of behavioral problems in Alzheimer's disease
Gauthier, S. G., Cummings, J. L., Ballard, C. G., Brodaty, H., Grossberg, G. T., Robert, P. H., & Lyketsos, C. G. (2010) · International Psychogeriatrics · doi:10.1017/s1041610209991505 · Cited by 379
Self-citation
Research works printed but not linked: 1
- O'Neil M, 2011, Non‐Pharmacological Interventions for Behavioral Symptoms of Dementia: A Systematic Review of the Evidence
Cited by
Sorted by citations
Dementia prevention, intervention, and care: 2020 report of the Lancet Commission
Livingston, G., Huntley, J., Sommerlad, A., Ames, D., Ballard, C., Banerjee, S., Brayne, C., Burns, A., Cohen-Mansfield, J., Cooper, C., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30367-6 · Cited by 10,430
Self-citationRetractedDementia prevention, intervention, and care
Livingston, G., Sommerlad, A., Orgeta, V., Costafreda, S. G., Huntley, J., Ames, D., Ballard, C., Banerjee, S., Burns, A., Cohen-Mansfield, J., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)31363-6 · Cited by 6,072
Self-citationAssessment and management of behavioral and psychological symptoms of dementia
Kales, H. C., Gitlin, L. N., & Lyketsos, C. G. (2015) · BMJ · doi:10.1136/bmj.h369 · Cited by 1,247
Self-citationGitlin, L. N., Marx, K., Stanley, I. H., & Hodgson, N. (2015) · The Gerontologist · doi:10.1093/geront/gnu123 · Cited by 336
Self-citationBest practice in the management of behavioural and psychological symptoms of dementia
Tible, O., Riese, F., Savaskan, E., & von Gunten, A. (2017) · Therapeutic Advances in Neurological Disorders · doi:10.1177/1756285617712979 · Cited by 328
Scales, K., Zimmerman, S. I., & Miller, S. (2017) · The Gerontologist · doi:10.1093/geront/gnx167 · Cited by 297
Management of Behavioral and Psychological Symptoms of Dementia
Bessey, L. J., & Walaszek, A. (2019) · Current Psychiatry Reports · doi:10.1007/s11920-019-1049-5 · Cited by 288
Antipsychotic use in dementia: a systematic review of benefits and risks from meta-analyses
Tampi, R. R., Tampi, D. J., Balachandran, S., & Srinivasan, S. (2016) · Therapeutic Advances in Chronic Disease · doi:10.1177/2040622316658463 · Cited by 267
Kales, H. C., Lyketsos, C. G., Miller, E. M., & Ballard, C. (2019) · International Psychogeriatrics · doi:10.1017/s1041610218000534 · Cited by 220
Self-citationCummings, J. L., Lyketsos, C. G., Peskind, E. R., Porsteinsson, A. P., Mintzer, J. E., Scharre, D. W., De La Gandara, J. E., Agronin, M., Davis, C. S., Nguyen, U., et al. (2015) · JAMA · doi:10.1001/jama.2015.10214 · Cited by 209
Self-citationPsychosis in Alzheimer disease—mechanisms, genetics and therapeutic opportunities
Ismail, Z., Creese, B., Aarsland, D., Kales, H. C., Lyketsos, C. G., Sweet, R. A., & Ballard, C. (2022) · Nature Reviews Neurology · doi:10.1038/s41582-021-00597-3 · Cited by 189
Self-citationAssociation of Antipsychotic Use With Mortality Risk in Patients With Parkinson Disease
Weintraub, D. A., Chiang, C., Kim, H. M., Wilkinson, J. R., Marras, C., Stanislawski, B., Mamikonyan, E., & Kales, H. C. (2016) · JAMA Neurology · doi:10.1001/jamaneurol.2016.0031 · Cited by 169
Self-citationTetrahydrocannabinol for neuropsychiatric symptoms in dementia
van den Elsen, G. A. H., Ahmed, A. I. A., Verkes, R., Kramers, C., Feuth, T. B., Rosenberg, P. B., van der Marck, M. A., & Rikkert, M. G. M. O. (2015) · Neurology · doi:10.1212/wnl.0000000000001675 · Cited by 170
Determinants of behavioral and psychological symptoms of dementia: A scoping review of the evidence
Kolanowski, A., Boltz, M., Galik, E., Gitlin, L. N., Kales, H. C., Resnick, B., Van Haitsma, K. S., Knehans, A., Sutterlin, J. E., Sefcik, J. S., et al. (2017) · Nursing Outlook · doi:10.1016/j.outlook.2017.06.006 · Cited by 165
Self-citationKazui, H., Yoshiyama, K., Kanemoto, H., Suzuki, Y., Sato, S., Hashimoto, M., Ikeda, M., Tanaka, H., Hatada, Y., Matsushita, M., et al. (2016) · PLOS ONE · doi:10.1371/journal.pone.0161092 · Cited by 160
Hearing Loss and Cognition: What We Know and Where We Need to Go
Powell, D. S., Oh, E. S., Reed, N. S., Lin, F. R., & Deal, J. A. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.769405 · Cited by 172
Collaborative Transdisciplinary Team Approach for Dementia Care
Galvin, J. E., Valois, L., & Zweig, Y. (2014) · Neurodegenerative Disease Management · doi:10.2217/nmt.14.47 · Cited by 149
Björk, S., Juthberg, C., Lindkvist, M., Wimo, A. B., Sandman, P., Winblad, B. G., & Edvardsson, D. (2016) · BMC Geriatrics · doi:10.1186/s12877-016-0328-9 · Cited by 145
Peterson, K., Hahn, H., Lee, A. J., Madison, C. A., & Atri, A. (2016) · BMC Geriatrics · doi:10.1186/s12877-016-0338-7 · Cited by 144
Helfrich, C. D., Rose, A. J., Hartmann, C. W., van Bodegom‐Vos, L., Graham, I. D., Wood, S., Majerczyk, B. R., Good, C. B., POGACH, L. M., Ball, S. L., et al. (2018) · Journal of Evaluation in Clinical Practice · doi:10.1111/jep.12855 · Cited by 138
Suárez-González, A., Rajagopalan, J., Livingston, G., & Alladi, S. (2021) · EClinicalMedicine · doi:10.1016/j.eclinm.2021.101047 · Cited by 130
Maust, D. T., Kim, H. M., Chiang, C., & Kales, H. C. (2018) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2018.0379 · Cited by 131
Self-citationCanevelli, M., Valletta, M., Trebbastoni, A., Sarli, G., D’Antonio, F., Tariciotti, L., de Lena, C., & Bruno, G. (2016) · Frontiers in Medicine · doi:10.3389/fmed.2016.00073 · Cited by 125
Behavioral and psychological symptoms in Alzheimer's dementia and vascular dementia
Deardorff, W. J., & Grossberg, G. T. (2019) · Handbook of clinical neurology · doi:10.1016/b978-0-444-64012-3.00002-2 · Cited by 133
Treatment for Alzheimer's disease
Fox, N. C., Belder, C. R. S., Ballard, C. G., Kales, H. C., Mummery, C. J., Caramelli, P., Ciccarelli, O., Frederiksen, K. S., Gómez‐Isla, T., Ismail, Z., et al. (2025) · The Lancet · doi:10.1016/s0140-6736(25)01329-7 · Cited by 137
Self-citationPless, A., Ware, D., Saggu, S., Rehman, H., Morgan, J., & Wang, Q. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1263771 · Cited by 131
Ijaopo, E. O. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.199 · Cited by 114
Halpern, R., Seare, J., Tong, J., Hartry, A., Olaoye, A., & Aigbogun, M. S. (2018) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5030 · Cited by 111
Tampi, R. R., & Jeste, D. V. (2022) · American Journal of Psychiatry · doi:10.1176/appi.ajp.20220508 · Cited by 112
Managing Behavioral and Psychological Symptoms of Dementia
Gerlach, L. B., & Kales, H. C. (2017) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2017.10.010 · Cited by 95
Self-citationPerson-Centered Assessment and Care Planning
Molony, S. L., Kolanowski, A. M., Haitsma, K. S. V., & Rooney, K. E. (2017) · The Gerontologist · doi:10.1093/geront/gnx173 · Cited by 95
Hearing Impairment and Cognition in an Aging World
Powell, D. S., Oh, E. S., Lin, F. R., & Deal, J. A. (2021) · Journal of the Association for Research in Otolaryngology · doi:10.1007/s10162-021-00799-y · Cited by 92
Myhre, J., Saga, S., Malmedal, W., Ostaszkiewicz, J., & Nakrem, S. (2020) · BMC Health Services Research · doi:10.1186/s12913-020-5047-4 · Cited by 88
Sano, M., Cummings, J., Auer, S., Bergh, S., Fischer, C. E., Gerritsen, D., Grossberg, G., Ismail, Z., Lanctôt, K., Lapid, M. I., et al. (2024) · International Psychogeriatrics · doi:10.1017/s1041610222001041 · Cited by 91
A systematic review of non‐pharmacological treatments for apathy in dementia
Theleritis, C. G., Siarkos, K., Politis, A. A., Katirtzoglou, E. A., & Politis, A. M. (2017) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4783 · Cited by 88
Maust, D. T., Kales, H. C., McCammon, R. J., Blow, F. C., Leggett, A., & Langa, K. M. (2017) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2017.02.025 · Cited by 74
Self-citationKales, H. C., Gitlin, L. N., Stanislawski, B., Kim, H. M., Marx, K., Turnwald, M., Chiang, C., & Lyketsos, C. G. (2018) · BMC Geriatrics · doi:10.1186/s12877-018-0801-8 · Cited by 81
Self-citationKales, H. C., Gitlin, L. N., & Lyketsos, C. G. (2019) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2019.05.022 · Cited by 76
Self-citationKeszycki, R. M., Fisher, D. W., & Dong, H. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01109 · Cited by 79
Neuropsychiatric symptoms in dementia
Radue, R. M., Walaszek, A., & Asthana, S. (2019) · Handbook of clinical neurology · doi:10.1016/b978-0-12-804766-8.00024-8 · Cited by 70
Iaboni, A., Spasojevic, S. S., Newman, K., Martin, L. S., Wang, A. H., Ye, B., Mihailidis, A., & Khan, S. S. (2022) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.12305 · Cited by 75
Assessing neuropsychiatric symptoms in people with dementia: a systematic review of measures
Gitlin, L. N., Marx, K. A., Stanley, I. H., Hansen, B. R., & Van Haitsma, K. S. (2014) · International Psychogeriatrics · doi:10.1017/s1041610214001537 · Cited by 82
Self-citationOh, E. S., & Rabins, P. V. (2019) · Annals of Internal Medicine · doi:10.7326/aitc201909030 · Cited by 77
A 2025 update on treatment strategies for the Alzheimer’s disease spectrum
Wu, C.-K., & Fuh, J.-L. (2025) · Journal of the Chinese Medical Association · doi:10.1097/jcma.0000000000001252 · Cited by 77
Shim, M., Tilley, J. L., Im, S., Price, K., & Gonzalez, A. (2020) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988720957104 · Cited by 70
Holst, A., & Skär, L. (2017) · International Journal of Older People Nursing · doi:10.1111/opn.12158 · Cited by 68
Advances in Management of Neuropsychiatric Syndromes in Neurodegenerative Diseases
Cummings, J. L., Ritter, A. R., & Rothenberg, K. G. (2019) · Current Psychiatry Reports · doi:10.1007/s11920-019-1058-4 · Cited by 72
Diagnosis and Management of Neuropsychiatric Symptoms in Alzheimer’s Disease
Wolinsky, D., Drake, K., & Bostwick, J. R. (2018) · Current Psychiatry Reports · doi:10.1007/s11920-018-0978-8 · Cited by 73
An update on the advancements in the treatment of agitation in Alzheimer’s disease
Porsteinsson, A. P., & Antonsdottir, I. M. (2017) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2017.1307340 · Cited by 69
Neuropsychiatric Symptoms in Dementia: Considerations for Pharmacotherapy in the USA
Phan, S. V., Osae, S. P., Morgan, J. C., Inyang, M., & Fagan, S. C. (2019) · Drugs in R&D · doi:10.1007/s40268-019-0272-1 · Cited by 76
Zuidema, S. U., Johansson, A., Selbæk, G., Murray, M., Burns, A. S., Ballard, C. G., & Koopmans, R. T. C. M. (2015) · International Psychogeriatrics · doi:10.1017/s1041610215000745 · Cited by 70
Non-pharmacological Management of Behavioral Symptoms in Frontotemporal and Other Dementias
Barton, C., Ketelle, R., Merrilees, J. J., & Miller, B. L. (2016) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-015-0618-1 · Cited by 70
Särkämö, T., Laitinen, S., Numminen, A., Kurki, M., Johnson, J. K., & Rantanen, P. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-150453 · Cited by 72
Livingston, G., Barber, J., Marston, L., Stringer, A., Panca, M., Hunter, R., Cooper, C., Laybourne, A., La Frenais, F., Reeves, S., et al. (2019) · The Lancet Psychiatry · doi:10.1016/s2215-0366(19)30045-8 · Cited by 62
Chen, P., Guarino, P., Dysken, M. W., Pallaki, M., Asthana, S., Llorente, M. D., Love, S. B., Vertrees, J. E., Schellenberg, G. D., & Sano, M. C. (2018) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988718783897 · Cited by 65
Lichtwarck, B., Selbaek, G., Kirkevold, Ø., Rokstad, A. M. M., Benth, J. Š., Lindstrøm, J. C., & Bergh, S. (2018) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2017.05.015 · Cited by 59
Kolanowski, A. M., Fortinsky, R. H., Calkins, M. P., Devanand, D. P., Gould, E., Heller, T., Hodgson, N. A., Kales, H. C., Kaye, J. A., Lyketsos, C. G., et al. (2018) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2018.07.005 · Cited by 62
Self-citationPharmacological and Nonpharmacological Treatment for Apathy in Alzheimer Disease
Theleritis, C. G., Siarkos, K., Katirtzoglou, E. A., & Politis, A. M. (2016) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988716678684 · Cited by 63
Getting what they need when they need it
Werner, N. E., Stanislawski, B., Marx, K., Watkins, D. C., Kobayashi, M. A., Kales, H. C., & Gitlin, L. N. (2017) · Applied Clinical Informatics · doi:10.4338/aci-2016-07-ra-0122 · Cited by 60
Self-citationNeuropsychiatric symptoms associated with family caregiver burden and depression
Delfino, L. L., Komatsu, R. S., Komatsu, C., Neri, A. L., & Cachioni, M. (2021) · Dementia & Neuropsychologia · doi:10.1590/1980-57642021dn15-010014 · Cited by 60
Helvik, A., Selbæk, G., Benth, J. Š., Røen, I., & Bergh, S. (2018) · PLoS ONE · doi:10.1371/journal.pone.0206147 · Cited by 59
Cammisuli, D. M., Cipriani, G., Giusti, E. M., & Castelnuovo, G. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11195752 · Cited by 65
Cho, E., Shin, J., Seok, J. W., Lee, H., Lee, K. H., Jang, J., Heo, S., & Kang, B. (2022) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2022.104392 · Cited by 61
AVP-786 for the treatment of agitation in dementia of the Alzheimer’s type
Garay, R. P., & Grossberg, G. T. (2016) · Expert Opinion on Investigational Drugs · doi:10.1080/13543784.2017.1267726 · Cited by 58
Taipale, H. T., Gomm, W., Broich, K., Maier, W., Tolppanen, A., Tanskanen, A. J., Tiihonen, J., Hartikainen, S. A., & Haenisch, B. (2018) · Journal of the American Geriatrics Society · doi:10.1111/jgs.15358 · Cited by 58
Cognitive-Behavioral Therapy in Older Adults
Conti, E. C., Kraus-Schuman, C. A., & Stanley, M. A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-803457-6.00010-6 · Cited by 55
Supporting Caregivers of Rural Veterans Electronically (SCORE)
Hicken, B. L., Daniel, C. M., Luptak, M., Grant, M., Kilian, S., & Rupper, R. (2016) · The Journal of Rural Health · doi:10.1111/jrh.12195 · Cited by 54
Karel, M. J., Teri, L. L., McConnell, E. S., Visnic, S., & Karlin, B. E. (2015) · The Gerontologist · doi:10.1093/geront/gnv068 · Cited by 55
Cutuli, D., Decandia, D., Giacovazzo, G., & Coccurello, R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241914686 · Cited by 61
Neuropsychiatric Symptoms and Microglial Activation in Patients with Alzheimer Disease
Aguzzoli, C. S., Ferreira, P. C. L., Povala, G., Ferrari‐Souza, J. P., Bellaver, B., Soares, C., Zalzale, H., Lussier, F. Z., Rohden, F., Abbas, S., et al. (2023) · JAMA Network Open · doi:10.1001/jamanetworkopen.2023.45175 · Cited by 54
Koenig, A. M., Arnold, S. E., & Streim, J. E. (2015) · Current Psychiatry Reports · doi:10.1007/s11920-015-0640-7 · Cited by 56
Vacas, S. M., Stella, F., Loureiro, J. C., do Couto, F. S., Oliveira-Maia, A. J., & Forlenza, O. V. (2018) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5003 · Cited by 52
Rehabilitation to live better with dementia
Maki, Y., Sakurai, T., Okochi, J., Yamaguchi, H., & Toba, K. (2018) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.13517 · Cited by 59
Choi, J. W., Lee, K. S., & Han, E. (2021) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.190219 · Cited by 54
Emotional and Neuropsychiatric Disorders Associated with Alzheimer's Disease
Heilman, K. M., & Nadeau, S. E. (2022) · Neurotherapeutics · doi:10.1007/s13311-021-01172-w · Cited by 60
Hillen, J. B., Soulsby, N. R., Alderman, C., & Caughey, G. E. (2019) · Therapeutic Advances in Drug Safety · doi:10.1177/2042098619846993 · Cited by 53
Four-Repeat Tauopathies: Current Management and Future Treatments
VandeVrede, L. A., Ljubenkov, P. A., Rojas, J. C., Welch, A. E., & Boxer, A. L. (2020) · Neurotherapeutics · doi:10.1007/s13311-020-00888-5 · Cited by 55
Psychiatric Aspects of Dementia
Onyike, C. U. (2016) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000000302 · Cited by 55
Lozupone, M., Montagna, M. L., D’Urso, F., Piccininni, C., Sardone, R., Dibello, V., Giannelli, G., Solfrizzi, V., Greco, A., Daniele, A., et al. (2018) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2018.1471136 · Cited by 50
Progresses in treating agitation: a major clinical challenge in Alzheimer’s disease
Panza, F., Solfrizzi, V., Seripa, D., Imbimbo, B. P., Santamato, A., Lozupone, M., Prete, C., Greco, A., Pilotto, A., & Logroscino, G. (2015) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2015.1092520 · Cited by 49
Marx, K., Stanley, I. H., Haitsma, K. S. V., Moody, J., Alonzi, D., Hansen, B. R., & Gitlin, L. N. (2014) · Journal of Gerontological Nursing · doi:10.3928/00989134-20140905-01 · Cited by 48
Self-citationGkioka, M., Schneider, J., Kruse, A., Tsolaki, M., Moraitou, D., & Teichmann, B. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200741 · Cited by 47
Novelli, M. M. P. C., Machado, S. C. B., Lima, G. B., Cantatore, L., Sena, B. P., Rodrigues, R. S., Rodrigues, C. I. B., Canon, M. B. F., Piersol, C. V., Nitrini, R., et al. (2018) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0000000000000256 · Cited by 46
Self-citationChen, Y., Su, J., Chen, J., Liu, C.-H., Griffiths, M. D., Tsai, H., Chang, C., & Lin, C. (2023) · BMC Geriatrics · doi:10.1186/s12877-023-03735-2 · Cited by 46
Dowson, B., McDermott, O., & Schneider, J. M. (2019) · Maturitas · doi:10.1016/j.maturitas.2019.06.001 · Cited by 45
Kolberg, E., Hjetland, G. J., Thun, E., Pallesen, S., Nordhus, I. H., Husebo, B. S., & Flo, E. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03376-y · Cited by 49
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Metadata
- Authors
- Kales, H. C., Gitlin, L. N., Lyketsos, C. G., & Dementia, T. D. E. P. O. T. A. A. M. O. T. N. S. O.
- Affiliations
- University of Michigan (US)
- Johns Hopkins University (US)
- Corresponding author
- Kales, Helen C.
- Venue
- Journal of the American Geriatrics Society
- Publisher
- Wiley
- Published
- 2014-03-17
- Volume
- 62
- Issue
- 4
- Pages
- 762-769
- ISSN
- 0002-8614 (ISSN-L)
- 1532-5415
- PMC
- PMC4146407
- OpenAlex
- W1976117775
- Cited by
- 575
- References
- 38
- Citations by year
- 2026: 27 · 2025: 43 · 2024: 60 · 2023: 47 · 2022: 53 · 2021: 58 · 2020: 54 · 2019: 38 · 2018: 55 · 2017: 48 · 2016: 49 · 2015: 29 · 2014: 13
- FWCI
- 6.38
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of the American Geriatrics Society (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institutes of Health (NIH)
- Alzheimer's Association
- National Institute of Mental Health
- National Institute on Aging
- Associated Jewish Federation of Baltimore
- Weinberg Foundation
- Forest
- GlaxoSmithKline
- Eisai
- Pfizer
- AstraZeneca
- Lilly
- Ortho-McNeil
- Bristol-Myers
- Novartis
- National Football League (NFL)
- Elan
- Functional Neuromodulation Inc.
- Johns Hopkins Alzheimer's Disease Research Center (P50AG005146)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Medicine › Geriatrics and Gerontology › Geriatric Care and Nursing Homes
- Keywords
- dementia, agitation, aggression, depression, anxiety, delusions, hallucinations, apathy, disinhibition, psychotropic drugs, adverse effects, non-pharmacological treatment, integrated treatment, clinical guidelines, caregiver burden, nursing home admission
- MeSH terms
- Behavior Therapy, Crisis Intervention, Dementia, Humans, Neuropsychological Tests, Severity of Illness Index, Practice Guidelines as Topic, Disease Management
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