The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Cholinergic modulation of the hippocampal region and memory function
Open accessAbstract
Acetylcholine (AC h) plays an important role in memory function and has been implicated in aging‐related dementia, in which the impairment of hippocampus‐dependent learning strongly manifests. Cholinergic neurons densely innervate the hippocampus, mediating the formation of episodic as well as semantic memory. Here, we will review recent findings on acetylcholine's modulation of memory function, with a particular focus on hippocampus‐dependent learning, and the circuits involved. In addition, we will discuss the complexity of AC h actions in memory function to better understand the physiological role of AC h in memory. This is an article for the special issue XVth International Symposium on Cholinergic Mechanisms. image
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Cites
Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain
Whitehouse, P., Price, D., Struble, R., Clark, A., Coyle, J., & DeLong, M. R. (1982) · Science · doi:10.1126/science.7058341 · Cited by 3,627
Rasch, B., & Born, J. (2013) · Physiological Reviews · doi:10.1152/physrev.00032.2012 · Cited by 2,783 · cited 1×
“Memory encoding and consolidation processes can interfere with each other and are therefore temporally separated (Hasselmo 1999; Rasch and Born 2013; Stickgold and Walker 2013).”
BackgroundThe cholinergic hypothesis of Alzheimer’s disease: A review of progress
Francis, P. T., Palmer, A. M., Snape, M., & Wilcock, G. K. (1999) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.66.2.137 · Cited by 2,198
Alzheimer Mechanisms and Therapeutic Strategies
Huang, Y., & Mucke, L. (2012) · Cell · doi:10.1016/j.cell.2012.02.040 · Cited by 1,758
Mammalian nicotinic acetylcholine receptors: from structure to function
Albuquerque, E. X., Pereira, E. F. R., Alkondon, M., & Rogers, S. W. (2009) · Physiological Reviews · doi:10.1152/physrev.00015.2008 · Cited by 1,724
Two-stage model of memory trace formation: A role for “noisy” brain states
Buzsáki, G. (1989) · Neuroscience · doi:10.1016/0306-4522(89)90423-5 · Cited by 1,709
The hippocampus and memory: insights from spatial processing
Bird, C. M., & Burgess, N. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2335 · Cited by 1,313
Cumulative Use of Strong Anticholinergics and Incident Dementia: A Prospective Cohort Study
Gray, S. L., Anderson, M. L., Dublin, S., Hanlon, J. T., Hubbard, R., Walker, R., Yu, O., Crane, P. K., & Larson, E. B. (2015) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2014.7663 · Cited by 1,111
The acute effects of corticosteroids on cognition: integration of animal and human model studies
LUPIEN, S., & MCEWEN, B. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00004-0 · Cited by 1,024
Intraneuronal Aβ42 Accumulation in Human Brain
Gouras, G. K., Tsai, J., Naslund, J., Vincent, B., Edgar, M., Checler, F., Greenfield, J. P., Haroutunian, V., Buxbaum, J. D., Xu, H., et al. (2000) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)64700-1 · Cited by 991
Cited by
Pan, W., Zhao, J., Wu, J., Xu, D., Meng, X., Jiang, P., Shi, H., Ge, X., Yang, X., Hu, M., et al. (2023) · Microbiome · doi:10.1186/s40168-023-01471-8 · Cited by 113
Microglia and Astrocytes in Alzheimer’s Disease: Significance and Summary of Recent Advances
Deng, Q., Wu, C., Parker, E., Liu, T. C.-Y., Duan, R., & Yang, L. (2023) · Aging and disease · doi:10.14336/ad.2023.0907 · Cited by 102
Viel, T., Toricelli, M., Pereira, A. R., Souza Abrao, G., Malerba, H., Maia, J., & Buck, H. (2021) · Neural Regeneration Research · doi:10.4103/1673-5374.286952 · Cited by 102
Low-dose ladostigil for mild cognitive impairment: A phase 2 placebo-controlled clinical trial
Schneider, L. S., Geffen, Y., Rabinowitz, J., Thomas, R. G., Schmidt, R., Ropele, S., Weinstock, M., & on behalf of the Ladostigil Study Group (2019) · Neurology · doi:10.1212/wnl.0000000000008239 · Cited by 75
Akyuz, E., Arulsamy, A., Aslan, F. S., Sarisözen, B., Guney, B., Hekimoglu, A., Yilmaz, B. N., Retinasamy, T., & Shaikh, M. F. (2025) · Molecular Neurobiology · doi:10.1007/s12035-024-04333-y · Cited by 69
Metadata
- Authors
- Haam, J., & Yakel, J. L.
- Venue
- Journal of Neurochemistry
- Publisher
- Wiley
- Published
- 2017-08
- Volume
- 142
- Issue
- S2
- Pages
- 111-121
- ISSN
- 0022-3042 (ISSN-L)
- 1471-4159
- OpenAlex
- W2743627045
- Cited by
- 450
- References
- 38
- FWCI
- 9.73
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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