Electronic messaging support service programs improve adherence to lipid‐lowering therapy among outpatients with coronary artery disease: an exploratory randomised control study
Abstract
Aims and objectives: To compare drug adherence to lipid‐lowering therapy among outpatients with coronary artery disease who received information via short message service, via short message service and Micro Letter, or via phone only. Background: Messaging applications and short message service are commonly used internationally. However, little is known about how coronary artery disease outpatients in China may benefit from receiving health education through these technologies. Design: Random sampling method. Methods: Data were collected from March–December 2013. Subjects from Chengdu City, China, were randomised to three groups: short message service, short message service + Micro Letter, and phone (control). Appointment reminders and health information were delivered to patients in accordance with designations. After six months, adherence to statin prescriptions was compared among the groups by using the Morisky Medication Adherence Scale. Logistic regression analysis was applied to determine those independent variables that were related to adherence. Results: The short message service and short message service + Micro Letter groups had better cumulative adherence (lower Morisky Medication Adherence Scale scores) after six months than phone group, and the short message service + Micro Letter group had better cumulative adherence (lower Morisky Medication Adherence Scale scores) than the short message service group. Female sex, older age and marriage show positive associations with adherence. Conclusions: Short message service and messaging applications, such as Micro Letter, are effective means of providing discharged patients with reminders and coronary artery disease‐related health information. Implementation of a short message service + Micro Letter program can improve outpatient adherence to medication. Relevance to clinical practice: This research offers useful information to help medical staff design effective interventions to improve medication compliance among coronary artery disease patients.
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Training on the use of devices such as cell phones and mobile apps, and on sharing and receiving text messages, will improve performance and increase the acceptability of mHealth within the community.
“Training on the use of devices, such as cell phones and mobile apps, and on sharing and receiving text messages will not only improve the performance but also increase the acceptability of mHealth within the community [39,46].”
From Barriers to the Use of Mobile Health in Improving Health Outcomes in Developing Countries: Systematic Review (2019) · cites this paper as [46]
Cites
Sacks, F. M., Pfeffer, M. A., Moye, L. A., Rouleau, J. L., Rutherford, J. D., Cole, T. G., Brown, L., Warnica, J. W., Arnold, J. M. O., Wun, C.-C., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199610033351401 · Cited by 7,439 · see citing works
Concurrent and Predictive Validity of a Self-reported Measure of Medication Adherence
Morisky, D. E., Green, L. W., & Levine, D. M. (1986) · Medical Care · doi:10.1097/00005650-198601000-00007 · Cited by 5,304 · see citing works
(1998) · New England Journal of Medicine · doi:10.1056/nejm199811053391902 · Cited by 5,261 · see citing works
Pedersen, T. R. (2004) · Atherosclerosis Supplements · doi:10.1016/j.atherosclerosissup.2004.08.027 · Cited by 3,098 · see citing works
Smith, S. C., Allen, J. K., Blair, S. N., Bonow, R. O., Brass, L. M., Fonarow, G. C., Grundy, S. M., Hiratzka, L. F., Jones, D. W., Krumholz, H. M., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.174516 · Cited by 2,087 · see citing works
Medication Adherence: Its Importance in Cardiovascular Outcomes
Ho, P. M., Bryson, C. L., & Rumsfeld, J. S. (2009) · Circulation · doi:10.1161/circulationaha.108.768986 · Cited by 1,488 · see citing works
Guidelines on the management of stable angina pectoris: executive summary
Authors/Task Force Members, Fox, K. M., Garcia, M. A. A., Ardissino, D., Buszman, P. E., Camici, P. G., Crea, F., Daly, C., Backer, G. D., Hjemdahl, P., et al. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehl001 · Cited by 1,324 · see citing works
Coronary artery disease in the developing world
Okrainec, K., Banerjee, D. K., & Eisenberg, M. J. (2004) · American Heart Journal · doi:10.1016/j.ahj.2003.11.027 · Cited by 430 · see citing works
Mobile Phone Interventions to Increase Physical Activity and Reduce Weight
Stephens, J. D., & Allen, J. K. (2013) · The Journal of Cardiovascular Nursing · doi:10.1097/jcn.0b013e318250a3e7 · Cited by 365 · see citing works
Use of Lipid-Lowering Medications at Discharge in Patients With Acute Myocardial Infarction
Fonarow, G. C., French, W. J., Parsons, L. S., Sun, H., & Malmgren, J. A. (2001) · Circulation · doi:10.1161/01.cir.103.1.38 · Cited by 226 · see citing works
Intentional and Unintentional Nonadherence to Antihypertensive Medication
Lowry, K. P., Dudley, T. K., Oddone, E. Ž., & Bosworth, H. B. (2005) · Annals of Pharmacotherapy · doi:10.1345/aph.1e594 · Cited by 218 · see citing works
Chen, Y.-F., Madan, J. J., Welton, N. J., Yahaya, I., Aveyard, P. N., Bauld, L., Wang, D., Fry-Smith, A., & Munafo, M. R. (2012) · Health Technology Assessment · doi:10.3310/hta16380 · Cited by 165 · see citing works
Rajpura, J. R., & Nayak, R. (2014) · Journal of Managed Care Pharmacy · doi:10.18553/jmcp.2014.20.1.58 · Cited by 152 · see citing works
Interventions to improve adherence to lipid lowering medication
Schedlbauer, A., Davies, P. A., & Fahey, T. P. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004371.pub3 · Cited by 148 · see citing works
The current state of cardiology in China
Cheng, T. O. (2004) · International Journal of Cardiology · doi:10.1016/j.ijcard.2003.10.011 · Cited by 113 · see citing works
Hussein, W. I., Hasan, K., & Jaradat, A. (2011) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2011.07.025 · Cited by 106 · see citing works
Thomas, R. J., King, M. L., Lui, K., Oldridge, N., Piña, I. L., & Spertus, J. A. (2007) · Journal of Cardiopulmonary Rehabilitation and Prevention · doi:10.1097/01.hcr.0000291295.24776.7b · Cited by 57 · see citing works
Lauck, S., Johnson, J. L., & Ratner, P. A. (2009) · European Journal of Cardiovascular Nursing · doi:10.1016/j.ejcnurse.2008.12.002 · Cited by 55 · see citing works
Statin Treatment Non-adherence and Discontinuation: Clinical Implications and Potential Solutions
Phan, K., Sandoval, Y.-H. G., Elbaz, L., et al. (2014) · Current Pharmaceutical Design · doi:10.2174/1381612820666140620162629 · Cited by 51 · see citing works
The association between multimorbidity and poor adherence with cardiovascular medications
Wong, M. C. S., Liu, J., Zhou, S., Li, S., Su, X., Wang, H., Chung, R. Y., Yip, B. H. K., Wong, S. Y. S., & Lau, J. T. F. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.09.103 · Cited by 50 · see citing works
Proactive Pharmaceutical Care Interventions Improve Patients’ Adherence to Lipid-Lowering Medication
Stuurman-Bieze, A. G. G., Hiddink, E., van Boven, J. F. M., et al. (2013) · Annals of Pharmacotherapy · doi:10.1177/1060028013501146 · Cited by 42 · see citing works
Adams, W. G. (2012) · JAMA · doi:10.1001/jama.2012.524 · Cited by 30 · see citing works
Update on the medical treatment of stable angina
Gayet, J.-L., Paganelli, F. F., & Solal, A. C. (2011) · Archives of cardiovascular diseases · doi:10.1016/j.acvd.2011.08.001 · Cited by 26 · see citing works
[Polypharmacy issues in older adults].
Chiang‐Hanisko, L., Tan, J., & Chiang, L.-C. (2014) · PubMed · doi:10.6224/jn.61.3.97 · Cited by 24 · see citing works
Statins: balancing benefits, efficacy and safety
Clearfield, M. B. (2002) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.3.5.469 · Cited by 11 · see citing works
Kitagawa, Y., Teramoto, T., & Daida, H. (2012) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.12682 · Cited by 8 · see citing works
Magometschnigg, D., & Rothmayer, G. (2011) · Wiener Medizinische Wochenschrift · doi:10.1007/s10354-011-0010-y · Cited by 3 · see citing works
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Kruse, C., Betancourt, J., Ortiz, S., Valdes Luna, S. M., Bamrah, I. K., & Segovia, N. (2019) · Journal of Medical Internet Research · doi:10.2196/13263 · Cited by 299 · see citing works
Gandapur, Y., Kianoush, S., Kelli, H. M., Misra, S., Urrea, B., Blaha, M. J., Graham, G., Marvel, F. A., & Martin, S. S. (2016) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcw018 · Cited by 202 · see citing works
Brørs, G., Pettersen, T. R., Hansen, T. B., Fridlund, B., Hølvold, L. B., Lund, H., & Norekvål, T. M. (2019) · BMC Health Services Research · doi:10.1186/s12913-019-4106-1 · Cited by 67 · see citing works
Sua, Y. S., Jiang, Y., Thompson, D. R., & Wang, W. (2020) · European Journal of Cardiovascular Nursing · doi:10.1177/1474515119895678 · Cited by 52 · see citing works
Fang, R., & Deng, X. (2018) · Journal of Clinical Nursing · doi:10.1111/jocn.13962 · Cited by 27 · see citing works
Self-citation
- Authors
- Fang, R., & Li, X.
- Affiliations
- Sichuan University (CN)
- Corresponding author
- Fang, Ronghua
- ORCID
- Venue
- Journal of Clinical Nursing
- Publisher
- Wiley
- Published
- 2015-11
- Volume
- 25
- Issue
- 5-6
- Pages
- 664-671
- ISSN
- 0962-1067 (ISSN-L)
- 1365-2702
- OpenAlex
- W2166259143
- Cited by
- 49
- References
- 27
- Citations by year
- 2025: 4 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 7 · 2020: 10 · 2019: 8 · 2018: 4 · 2017: 5 · 2016: 4
- FWCI
- 7.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Nursing (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Health Professions › Health Information Management › Health, Technology, Consumer Behavior
- Keywords
- medication adherence, lipid-lowering therapy, statins, coronary artery disease, short message service, mobile health messaging, appointment reminders, health education, outpatients, Morisky Medication Adherence Scale, predictors of adherence
- MeSH terms
- Adult, Aged, Ambulatory Care, Hypolipidemic Agents, China, Coronary Artery Disease, Female, Humans, Male, Middle Aged, Patient Discharge, Reminder Systems, Medication Adherence, Text Messaging
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