The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Natural products to prevent drug resistance in cancer chemotherapy: a review
Abstract
Chemotherapy is the standard internal medical treatment for cancer. However, the resistance of cancer cells to nearly all kinds of chemotherapeutic drugs and targeted drugs has become prevalent, and approximately 80–90% of deaths in cancer patients are directly or indirectly attributed to drug resistance. The progress of new drug research and development has also been impeded by the occurrence of drug resistance, which has emerged as a considerable challenge in cancer therapy. Fortunately, natural products with diverse chemical structures and pharmacological effects serve as effective substances against drug resistance. Since the discovery of a series of drug‐resistant proteins, drug‐efflux inhibition has been applied as the primary strategy to overcome drug resistance by maintaining the intracellular concentrations of chemotherapeutic drugs. Nonapoptotic cell death is considered an alternative strategy because most cases of drug resistance result in evasion and insensitivity to apoptosis. In this concise review, we summarize two strategies using natural products against drug resistance.
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The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy
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Natural compounds as potential adjuvants to cancer therapy: Preclinical evidence
Lin, S., Chang, C., Hsu, C., Tsai, M., Cheng, H., Leong, M. K., Sung, P., Chen, J., & Weng, C. (2020) · British Journal of Pharmacology · doi:10.1111/bph.14816 · Cited by 425
Stress and coping in women with breast cancer:unravelling the mechanisms to improve resilience
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A Review on Annona muricata and Its Anticancer Activity
Ilango, S., Sahoo, D. K., Paital, B., Kathirvel, K., Gabriel, J. I., Subramaniam, K., Jayachandran, P., Dash, R. K., Hati, A. K., Behera, T. R., et al. (2022) · Cancers · doi:10.3390/cancers14184539 · Cited by 91
Metadata
- Authors
- Yuan, R., Hou, Y., Sun, W., Yu, J., Liu, X., Niu, Y., Lu, J., & Chen, X.
- Venue
- Annals of the New York Academy of Sciences
- Publisher
- Wiley
- Published
- 2017-08
- Volume
- 1401
- Issue
- 1
- Pages
- 19-27
- ISSN
- 0077-8923 (ISSN-L)
- 1749-6632
- OpenAlex
- W2754437817
- Cited by
- 196
- References
- 10
- FWCI
- 6.25
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yuan, R., Hou, Y., Sun, W., Yu, J., Liu, X., Niu, Y., Lu, J., & Chen, X. (2017). Natural products to prevent drug resistance in cancer chemotherapy: a review. Annals of the New York Academy of Sciences. https://doi.org/10.1111/nyas.13387
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