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Cited by 114Cardiovascular Disease and AdiposityAdipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

Comparison of reducing epicardial fat by exercise, diet or bariatric surgery weight loss strategies: A systematic review and meta-analysis

Rabkin, S. W., Campbell, H.·2015·Obesity Reviews
DOI 10.1111/obr.12270
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Abstract

The objectives were to determine whether epicardial fat (EAT) is subject to modification, and whether various strategies accomplish this end point and the relationship between weight loss and EAT. A systematic review of the literature following meta-analysis guidelines was conducted using the search strategy 'epicardial fat' OR 'epicardial adipose tissue' AND 'diet' OR 'exercise' OR 'bariatric surgery (BS)' OR 'change in body weight' limited to humans. Eleven articles were identified with 12 intervention approaches of which eight studies showed a statistically significant reduction in EAT. A random-effects meta-analysis suggests an overall significant reduction of 1.12 standardized units (95% CI = [-1.71, -0.54], P value < 0.01). While there is a large amount of heterogeneity across study groups, a substantial amount of this variability can be accounted for by considering intervention type and change in body mass index (BMI). These variables were incorporated into a random-effects meta-regression model. Using this analysis, significant EAT reduction occurred with diet and BS but not with exercise. BMI reductions correlated significantly with EAT reductions for diet-based interventions, i.e. for some but not all interventions. In conclusion, EAT, a factor that is significantly associated with coronary artery disease, can be modified. The type of intervention, in addition to the amount of weight loss achieved, is predictive of the amount of EAT reduction.

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Crossref · 10.1111/obr.12270

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  1. Rabkin SW, 2014, Handbook of Systems Biology of Oxidative Stress, 1021

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Metadata

Authors
Rabkin, S. W., & Campbell, H.
Affiliations
  • University of British Columbia (CA)
  • EMMES Canada Burnaby BC Canada
Corresponding author
Rabkin, S. W.
ORCID
Rabkin, S. W.
Venue
Obesity Reviews
Publisher
Wiley
Published
2015-03-05
Volume
16
Issue
5
Pages
406-415
ISSN
  • 1467-7881 (ISSN-L)
  • 1467-789X
DOI
10.1111/obr.12270
OpenAlex
W1518443297
Cited by
114
References
38
Citations by year
2026: 1 · 2025: 3 · 2024: 8 · 2023: 16 · 2022: 15 · 2021: 10 · 2020: 12 · 2019: 18 · 2018: 8 · 2017: 14 · 2016: 7 · 2015: 2
FWCI
1.78
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Obesity Reviews (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
  • Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
Keywords
epicardial adipose tissue, visceral fat reduction, weight loss interventions, diet, physical activity, bariatric surgery, body mass index, coronary artery disease
MeSH terms
Adipose Tissue, Diet, Reducing, Humans, Obesity, Pericardium, Risk Factors, Weight Loss, Exercise, Treatment Outcome, Bariatric Surgery

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