The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
IL‐17: overview and role in oral immunity and microbiome
Open accessAbstract
Interleukin‐17 (IL‐17) is a multifaceted cytokine with diverse roles in both immune protection and also immunopathology. IL‐17 has a well‐recognized role in immune surveillance at mucosal and barrier surfaces, but also has been increasingly implicated as a driver of immunopathology in settings of autoimmunity and chronic inflammation. The current review introduces basic aspects of IL‐17 biology and examines the protective and pathogenic roles of IL‐17 with a focus on oral mucosal immunity and inflammation. Specific emphasis is given to the role of the IL‐17 response as a catalyst in ‘shaping the microbiome at the oral barrier’.
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Citations
Cites
Exploring the full spectrum of macrophage activation
Mosser, D. M., & Edwards, J. P. (2008) · Nature Reviews Immunology · doi:10.1038/nri2448 · Cited by 9,144 · cited 1×
“Lastly, macrophages are reported to increase their production of the pro-inflammatory cytokines IL-1β and TNF-α upon IL-17 stimulation, further amplifying inflammatory responses (Jovanovic et al., 1998, Mosser & Edwards, 2008).”
Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L., & Kuchroo, V. K. (2006) · Nature · doi:10.1038/nature04753 · Cited by 6,992
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Harrington, L. E., Hatton, R. D., Mangan, P. R., Turner, H., Murphy, T. L., Murphy, K. M., & Weaver, C. T. (2005) · Nature Immunology · doi:10.1038/ni1254 · Cited by 4,742
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
Langrish, C. L., Chen, Y., Blumenschein, W. M., Mattson, J., Basham, B., Sedgwick, J. D., McClanahan, T., Kastelein, R. A., & Cua, D. J. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20041257 · Cited by 4,099
Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M., & Stockinger, B. (2006) · Immunity · doi:10.1016/j.immuni.2006.01.001 · Cited by 3,605 · cited 1×
“Differentiation of murine Th17 cells has been shown to be dependent on transforming growth factor β (TGF-β) and IL-6 (Veldhoen et al., 2006, Bettelli et al., 2006, Mangan et al., 2006), whereas human Th17 cells can be induced in the presence of TGF-β/IL-1β, IL-6 and IL-23 (Acosta-Rodriguez et al.,…”
Transforming growth factor-β induces development of the TH17 lineage
Mangan, P. R., Harrington, L. E., O'Quinn, D. B., Helms, W. S., Bullard, D. C., Elson, C. O., Hatton, R. D., Wahl, S. M., Schoeb, T. R., & Weaver, C. T. (2006) · Nature · doi:10.1038/nature04754 · Cited by 3,087
Liang, S. C., Tan, X.-Y., Luxenberg, D. P., Karim, R., Dunussi-Joannopoulos, K., Collins, M., & Fouser, L. A. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20061308 · Cited by 2,330
Secukinumab in plaque psoriasis—results of two phase 3 trials
Langley, R. G., Elewski, B. E., Lebwohl, M., Reich, K., Griffiths, C. E. M., Papp, K., Puig, L., Nakagawa, H., Spelman, L., Sigurgeirsson, B., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1314258 · Cited by 1,997 · cited 1×
“Specifically, to date Secukinumab the human IL-17 antagonist has been FDA approved for the treatment of psoriatic arthritis, ankylosing spondylitis and plaque psoriasis (Langley et al., 2014).”
Acosta-Rodriguez, E. V., Napolitani, G., Lanzavecchia, A., & Sallusto, F. (2007) · Nature Immunology · doi:10.1038/ni1496 · Cited by 1,857
Cited by
The cytokine network involved in the host immune response to periodontitis
Pan, W., Wang, Q., & Chen, Q. (2019) · International Journal of Oral Science · doi:10.1038/s41368-019-0064-z · Cited by 696
Bharath, L. P., Agrawal, M., McCambridge, G., Nicholas, D. A., Hasturk, H., Liu, J., Jiang, K., Liu, R., Guo, Z., Deeney, J., et al. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2020.04.015 · Cited by 614
The oral microbiota is modified by systemic diseases.
Graves, D. T., Corrêa, J. D., & Silva, T. A. (2019) · Journal of Dental Research · doi:10.1177/0022034518805739 · Cited by 423
Tissue-Specific Immunity at the Oral Mucosal Barrier
Moutsopoulos, N. M., & Konkel, J. E. (2018) · Trends in Immunology · doi:10.1016/j.it.2017.08.005 · Cited by 409
Self-citationThe impact of diabetes on periodontal diseases
Graves, D. T., Ding, Z., & Yang, Y. (2020) · Periodontology 2000 · doi:10.1111/prd.12318 · Cited by 398
Metadata
- Authors
- Abusleme, L., & Moutsopoulos, N.
- Venue
- Oral Diseases
- Publisher
- Wiley
- Published
- 2016-12-27
- Volume
- 23
- Issue
- 7
- Pages
- 854-865
- ISSN
- 1354-523X (ISSN-L)
- 1601-0825
- OpenAlex
- W2536653177
- Cited by
- 183
- References
- 44
- FWCI
- 14.35
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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