Prospective Study of Major Loss Life Events and Risk for Suicidal Thoughts and Behaviors Among Adolescents and Young Adults
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This prospective, naturalistic study examined the association between major loss life experiences, other psychiatric risk factors (depression, hopelessness, and anxiety), and suicidal thoughts and behaviors (STB s) among adolescents followed through young adulthood for up to 14 years. Major loss life events were related to subsequent increases in STB s. Major loss life events were primarily related to increases in suicide ideation in the presence of lower levels of other risk factors. There was a bidirectional relationship between major losses and other risk factors. Implications for the association between loss experiences, other risk factors, and future STB s are discussed.
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Research on depression and suicide points to a combination of trait and state factors.
“The research on depression and suicide points to a combination of trait and state factors (Daniel et al., 2017; Klonsky and May, 2015).”
From A hope intervention for adolescents: a randomized controlled trial delivered by paraprofessionals (2025) · cites this paper as Daniel et al., 2017
Three studies in clinical samples of adolescents found that major life events did not predict future suicide attempts after adjusting for psychiatric symptoms and suicide ideation.
“For example, three studies in clinical samples of adolescents found that, after adjusting for psychiatric symptoms and suicide ideation, major life events did not predict future suicide attempts (Daniel et al. 2017; Massing-Schaffer et al. 2019; Stone et al. 2014).”
From Life stress and suicide in adolescents (2019) · cites this paper as Daniel et al. 2017
Daniel and colleagues found that for those with low but not high depression symptoms, experiencing a major loss such as a romantic break-up was associated with attempts.
“and Daniel and colleagues (Daniel et al. 2017) found that for those with low (but not high) depression symptoms, experiencing a major loss (e.g., romantic break-up) was associated with attempts.”
From Life stress and suicide in adolescents (2019) · cites this paper as Daniel et al. 2017
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Suicide and Self-Directed Violence
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- Authors
- Daniel, S. S., Goldston, D. B., Erkanli, A., Heilbron, N., & Franklin, J. C.
- Affiliations
- Wake Forest University Health Sciences (US)
- Duke University (US)
- Florida State University (US)
- Corresponding author
- Daniel, Stephanie S.
- Venue
- Suicide and Life-Threatening Behavior
- Publisher
- Wiley
- Published
- 2016-11-10
- Volume
- 47
- Issue
- 4
- Pages
- 436-449
- ISSN
- 0363-0234 (ISSN-L)
- 1943-278X
- PMC
- PMC6485934
- OpenAlex
- W2552507010
- Cited by
- 25
- References
- 49
- Citations by year
- 2025: 2 · 2024: 4 · 2023: 4 · 2021: 3 · 2020: 1 · 2019: 5 · 2018: 6
- FWCI
- 4.91
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Suicide and Life-Threatening Behavior (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH048762)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Psychology › Clinical Psychology › Grief, Bereavement, and Mental Health
- Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
- Keywords
- life events, suicidal ideation, suicidal behavior, adolescents, young adults, depression, hopelessness, anxiety, psychiatric risk factors, longitudinal follow-up
- MeSH terms
- Adolescent, Adult, Anxiety, Child, Depression, Female, Humans, Life Change Events, Male, Prospective Studies, Risk Factors, Young Adult, Suicidal Ideation
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