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Caffeine improves various aspects of athletic performance in adolescents independent of their 163 C > A CYP1A2 genotypes

Spineli, Higor, Pinto, Maryssa P., Dos Santos, Bruna P., Lima‐Silva, Adriano E., Bertuzzi, Romulo, Gitaí, Daniel L. G., de Araujo, Gustavo G.·2020·Scandinavian Journal of Medicine & Science in Sports

Abstract

Purpose: The purpose of this study was to investigate whether variations in 163 C > A CYP1A2 genotypes (rs 762 551) (AA, AC, and CC) modify the ergogenic effects of caffeine (CAF) on strength, power, muscular endurance, agility, and endurance in adolescent athletes. Methods: One hundred adolescents (age = 15 ± 2 years) were recruited. Participants ingested CAF (6 mg.kg −1 ) or placebo (PLA, 300 mg of cellulose) 1 hour before performing a sequence of physical tests: handgrip strength, vertical jumps, agility test, sit‐ups, push‐ups, and the Yo‐Yo intermittent recovery test level 1 (Yo‐Yo IR1). Results: Compared to PLA, CAF enhanced ( P < .05) sit‐up (CAF = 37 ± 9; PLA = 35 ± 8 repetitions) and push‐up repetitions (CAF = 26 ± 11; PLA = 24 ± 11 repetitions), and increased distance covered in Yo‐Yo IR1 test (CAF = 1010.4 ± 378.9; PLA = 903.2 ± 325.7 m). There was no influence of CAF on handgrip strength (CAF = 35.1 ± 8.9; PLA = 33.7 ± 8.7 kgf), countermovement jump height (CAF = 49.3 ± 12.6; PLA = 47.9 ± 13.8 cm), spike jump height (CAF = 54.2 ± 13.6; PLA = 52.9 ± 14.5 cm), and time in agility test (CAF = 15.8 ± 1.1; PLA = 15.9 ± 1.3 s, P > .05). When present, the ergogenic effect of CAF was not dependent of genotype. Conclusion: CAF improves muscular endurance and aerobic performance in adolescent athletes, regardless of their 163 C > A CYP1A2 genotype.

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Metadata

Authors
Spineli, H., Pinto, M. P., Dos Santos, B. P., Lima‐Silva, A. E., Bertuzzi, R., Gitaí, D. L. G., & de Araujo, G. G.
Affiliations
  • Postgraduate Program in Nutrition – PPGNUT Federal University of Alagoas Alagoas Brazil
  • Postgraduate Program in Health Sciences – PPGCS Federal University of Alagoas Alagoas Brazil
  • Human Performance Research Group Technological Federal University of Parana Parana Brazil
  • Endurance Performance Research Group (GEDAE‐USP) School of Physical Education and Sport University of São Paulo São Paulo Brazil
Venue
Scandinavian Journal of Medicine & Science in Sports
Publisher
Wiley
Published
2020-07-13
Volume
30
Issue
10
Pages
1869-1877
ISSN
  • 0905-7188
  • 1600-0838
Cited by
37
References
10
Language
en
Funders
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (60030 1121/2015)
  • Fundação de Amparo à Pesquisa do Estado de Alagoas (60030 1121/2015)

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CoChat. (2026). Citation check: Caffeine improves various aspects of athletic performance in adolescents independent of their 163 C > A CYP1A2 genotypes. https://app.cochat.ai/papers/10.1111/sms.13749
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Spineli, H., Pinto, M. P., Dos Santos, B. P., Lima‐Silva, A. E., Bertuzzi, R., Gitaí, D. L. G., & de Araujo, G. G. (2020). Caffeine improves various aspects of athletic performance in adolescents independent of their 163 C > A CYP1A2 genotypes. Scandinavian Journal of Medicine & Science in Sports. https://doi.org/10.1111/sms.13749

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