Submicroscopic malaria infections in pregnant women from six departments in Haiti
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OBJECTIVES: To describe the epidemiology of malaria in pregnancy in Haiti. METHODS: Cross-sectional study among pregnant women in six departments of Haiti. After obtaining informed consent, whole blood samples and demographic surveys were collected to investigate malaria prevalence, anaemia and socio-behavioural risk factors for infection, respectively. A total of 311 pregnant women were screened for Plasmodium falciparum infection using a rapid diagnostic test (RDT), microscopy and a novel, quantitative reverse transcriptase polymerase chain reaction method (qRT-PCR). RESULTS: Overall, 1.2% (4/311) of pregnant women were tested positive for malaria infection by both microscopy and RDT. However, using the qRT-PCR, 16.4% (51/311) of pregnant women were positive. The prevalence of malaria infection varied with geographical locations ranging between 0% and 46.4%. Additionally, 53% of pregnant women had some form of anaemia; however, no significant association was found between anaemia and submicroscopic malaria infection. The socio-behavioural risk factors identified to be protective of malaria infection were marital status (P < 0.05) and travel within one month prior to screening (P < 0.05). CONCLUSION: This study is the first to document the high prevalence of submicroscopic malaria infections among pregnant women in Haiti and identify social and behavioural risk factors for disease transmission.
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Pregnant women are at higher risk for severe malaria, pregnancy loss and death compared to non-pregnant peers, with a mortality rate up to 50% for severe infections.
“Expectant mothers are also at higher risk for severe malaria, pregnancy loss and death compared to their non-pregnant peers, with a mortality rate up to 50% for severe infections [6].”
From Intermittent preventive treatment with Sulphadoxine-Pyrimethamine (IPTp-SP) is associated with protection against sub-microscopic P. falciparum infection in pregnant women during the low transmission dry season in southwestern Cameroon: A Semi - longitudinal study (2022) · cites this paper as [6]
The overall 39.9% prevalence of Plasmodium falciparum infection in this study mirrors previous reports.
“The overall 39.9% prevalence of Plasmodium falciparum infection in this study mirrors previous reports [6]”
From Intermittent preventive treatment with Sulphadoxine-Pyrimethamine (IPTp-SP) is associated with protection against sub-microscopic P. falciparum infection in pregnant women during the low transmission dry season in southwestern Cameroon: A Semi - longitudinal study (2022) · cites this paper as [6]
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- Authors
- Elbadry, M. A., Tagliamonte, M. S., Raccurt, C. P., Lemoine, J. F., Existe, A., Boncy, J., Weppelmann, T. A., Dame, J. B., & Okech, B. A.
- Affiliations
- University of Florida Health (US)
- University of Florida (US)
- Ministère de la Santé Publique et de la Population (HT)
- Florida International University (US)
- Corresponding author
- Elbadry, Maha A.
- ORCID
- Venue
- Tropical Medicine & International Health
- Publisher
- Wiley
- Published
- 2017-07-14
- Volume
- 22
- Issue
- 8
- Pages
- 1030-1036
- ISSN
- 1360-2276 (ISSN-L)
- 1365-3156
- OpenAlex
- W2625379881
- Cited by
- 21
- References
- 31
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 3 · 2022: 3 · 2021: 2 · 2020: 5 · 2019: 2 · 2018: 1
- FWCI
- 2.05
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Tropical Medicine & International Health (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Life Sciences › Immunology and Microbiology › Parasitology › Bird parasitology and diseases
- Health Sciences › Medicine › Genetics › Hemoglobinopathies and Related Disorders
- Keywords
- malaria in pregnancy, submicroscopic malaria infection, Plasmodium falciparum, malaria prevalence, anemia, marital status, travel, Haiti, malaria screening
- MeSH terms
- Adolescent, Adult, Anemia, Cross-Sectional Studies, Female, Haiti, Humans, Microscopy, Plasmodium falciparum, Pregnancy, Pregnancy Complications, Infectious, Risk Factors, Travel, Prevalence, Malaria, Falciparum, Marital Status, Reverse Transcriptase Polymerase Chain Reaction, Young Adult
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