The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Exercise‐induced oxidative stress: past, present and future
Open accessAbstract
The existence of free radicals in living cells was first reported in 1954 and this important finding helped launch the field of free radical biology. However, the discovery that muscular exercise is associated with increased biomarkers of oxidative stress did not occur until 1978. Following the initial report that exercise promotes oxidative stress in humans, many studies have confirmed that prolonged or short‐duration high intensity exercise results in increased radical production in active skeletal muscles resulting in the formation of oxidized lipids and proteins in the working muscles. Since these early descriptive studies, the investigation of radicals and redox biology related to exercise and skeletal muscle has grown as a discipline and the importance of this research in the biomedical sciences is widely recognized. This review will briefly summarize the history of research in exercise‐induced oxidative stress and will discuss the major paradigm shifts that the field has undergone and continues to experience. We conclude with a discussion of future directions in the hope of stimulating additional research in this important field.
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Cites
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“However, this concept began to change with the discovery that NO is the signalling molecule responsible for vasodilatation (Palmer et al. 1987).”
BackgroundFree radicals and tissue damage produced by exercise
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Cited by
Emerging roles of oxidative stress in brain aging and Alzheimer's disease
Ionescu-Tucker, A., & Cotman, C. W. (2021) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2021.07.014 · Cited by 737
Exercise-induced oxidative stress: Friend or foe?
Powers, S. K., Deminice, R., Ozdemir, M., Yoshihara, T., Bomkamp, M. P., & Hyatt, H. (2020) · Journal of Sport and Health Science · doi:10.1016/j.jshs.2020.04.001 · Cited by 655
Self-citationOxidative Stress in Type 2 Diabetes: Impacts from Pathogenesis to Lifestyle Modifications
Caturano, A., D’Angelo, M., Mormone, A., Russo, V., Mollica, M. P., Salvatore, T., Galiero, R., Rinaldi, L., Vetrano, E., Marfella, R., et al. (2023) · Current Issues in Molecular Biology · doi:10.3390/cimb45080420 · Cited by 579
Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise
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Sarcopenia: Molecular Pathways and Potential Targets for Intervention
Pascual-Fernández, J., Fernández-Montero, A., Córdova-Martínez, A., Pastor, D., Martínez-Rodríguez, A., & Roche, E. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228844 · Cited by 125
Metadata
- Authors
- Powers, S. K., Radak, Z., & Ji, L. L.
- Venue
- The Journal of Physiology
- Publisher
- Wiley
- Published
- 2016-02-19
- Volume
- 594
- Issue
- 18
- Pages
- 5081-5092
- ISSN
- 0022-3751 (ISSN-L)
- 1469-7793
- OpenAlex
- W2280104967
- Cited by
- 344
- References
- 10
- FWCI
- 27.59
- Type
- journal article
- Language
- en
- Open access
- green
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