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Cited by 156Transcranial Magnetic Stimulation StudiesMotor Control and AdaptationPeripheral Nerve Disorders

Motor cortical representation of the diaphragm in man.

Open access
Maskill, D, Murphy, K, Mier, A, Owen, M, Guz, A·1991·The Journal of Physiology
DOI 10.1113/jphysiol.1991.sp018825PMC PMC1179833
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Abstract

1. Transcranial magnetic stimulation was performed using a figure‐of‐eight‐shaped coil over the right motor cortex with the aim of identifying those areas involved with activation of the diaphragm. 2. The response of the right and left hemi‐diaphragms was recorded using surface electrodes in either the 7th or 8th intercostal spaces 3 cm lateral to the anterior costal margin on either side. 3. The compound muscle action potentials recorded over the left diaphragm in response to transcranial magnetic stimulation were maximal when the centre of the figure‐of‐eight coil was placed approximately 3 cm to the right of the mid‐line and 2‐3 cm anterior to the auricular plane. 4. The amplitude of the response recorded from the diaphragm depended upon the angulation of the figure‐of‐eight coil and hence the direction of the stimulating current. 5. The response of the inspiratory muscles to magnetic stimulation of one side of the brain was predominantly contralateral but a small response was seen on the ipsilateral side. Ultrasonic techniques confirmed that the diaphragm was responding contralaterally and not ipsilaterally.

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  • Stimulation of the motor cortex in humans elicits twitches in the diaphragm.

    “For instance, stimulation 152,153 of the motor cortex in humans elicits twitches in the diaphragm,”

    From Interoceptive rhythms in the brain (2023) · cites this paper as [153]

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Cites

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Research works printed but not linked: 20

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Cited by

Sorted by citations

Authors
Maskill, D., Murphy, K., Mier, A., Owen, M., & Guz, A.
Affiliations
Charing Cross Hospital (GB)
ORCID
Murphy, K
Venue
The Journal of Physiology
Publisher
Wiley
Published
1991-11
Volume
443
Issue
1
Pages
105-121
ISSN
  • 0022-3751 (ISSN-L)
  • 1469-7793
DOI
10.1113/jphysiol.1991.sp018825
PMC
PMC1179833
OpenAlex
W2017341951
Cited by
156
References
1
Citations by year
2026: 2 · 2025: 2 · 2024: 2 · 2023: 6 · 2022: 8 · 2021: 2 · 2020: 5 · 2019: 6 · 2018: 2 · 2017: 1 · 2016: 5 · 2015: 3 · 2014: 6 · 2013: 7 · 2012: 6
FWCI
2.19
Type
journal article
Language
en
Open access
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • The Journal of Physiology (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
Wellcome Trust
Topics
  • Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Peripheral Nerve Disorders
Keywords
diaphragm, motor cortex, transcranial magnetic stimulation, figure-of-eight coil, compound muscle action potential, contralateral activation, inspiratory muscles, hemidiaphragm
MeSH terms
Action Potentials, Adult, Diaphragm, Humans, Magnetics, Male, Middle Aged, Motor Cortex, Physical Stimulation, Respiratory Muscles

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