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Cited by 366

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

Biaxial Mechanical Properties of the Native and Glutaraldehyde-Treated Aortic Valve Cusp: Part II—A Structural Constitutive Model

Billiar, Kristen L., Sacks, Michael S.·2000·Journal of Biomechanical Engineering
DOI 10.1115/1.1287158
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Abstract

We have formulated the first constitutive model to describe the complete measured planar biaxial stress–strain relationship of the native and glutaraldehyde-treated aortic valve cusp using a structurally guided approach. When applied to native, zero-pressure fixed, and low-pressure fixed cusps, only three parameters were needed to simulate fully the highly anisotropic, and nonlinear in-plane biaxial mechanical behavior. Differences in the behavior of the native and zero- and low-pressure fixed cusps were found to be primarily due to changes in the effective fiber stress–strain behavior. Further, the model was able to account for the effects of small <10deg misalignments in the cuspal specimens with respect to the biaxial test axes that increased the accuracy of the model material parameters. Although based upon a simplified cuspal structure, the model underscored the role of the angular orientation of the fibers that completely accounted for extreme mechanical anisotropy and pronounced axial coupling. Knowledge of the mechanics of the aortic cusp derived from this model may aid in the understanding of fatigue damage in bioprosthetic heart valves and, potentially, lay the groundwork for the design of tissue-engineered scaffolds for replacement heart valves. [S0148-0731(00)00504-5]

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Metadata

Authors
Billiar, K. L., & Sacks, M. S.
Venue
Journal of Biomechanical Engineering
Publisher
ASME International
Published
2000-03-22
Volume
122
Issue
4
Pages
327-335
ISSN
  • 0148-0731 (ISSN-L)
  • 1528-8951
DOI
10.1115/1.1287158
OpenAlex
W2130081638
Cited by
366
References
23
FWCI
6.40
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Biaxial Mechanical Properties of the Native and Glutaraldehyde-Treated Aortic Valve Cusp: Part II—A Structural Constitutive Model. https://app.cochat.ai/papers/10.1115/1.1287158
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Billiar, K. L., & Sacks, M. S. (2000). Biaxial Mechanical Properties of the Native and Glutaraldehyde-Treated Aortic Valve Cusp: Part II—A Structural Constitutive Model. Journal of Biomechanical Engineering. https://doi.org/10.1115/1.1287158

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.