The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Optical Properties of Circulating Human Blood in the Wavelength Range 400–2500 nm
Open accessAbstract
Knowledge about the optical properties μa,μs, and g of human blood plays an important role for many diagnostic and therapeutic applications in laser medicine and medical diagnostics. They strongly depend on physiological parameters such as oxygen saturation, osmolarity, flow conditions, haematocrit, etc. The integrating sphere technique and inverse Monte Carlo simulations were applied to measure μa,μs, and g of circulating human blood. At 633 nm the optical properties of human blood with a haematocrit of 10% and an oxygen saturation of 98% were found to be 0.210±0.002 mm-1 for μa,77.3±0.5 mm-1 for μs, and 0.994±0.001 for the g factor. An increase of the haematocrit up to 50% lead to a linear increase of absorption and reduced scattering. Variations in osmolarity and wall shear rate led to changes of all three parameters while variations in the oxygen saturation only led to a significant change of the absorption coefficient. A spectrum of all three parameters was measured in the wavelength range 400-2500 nm for oxygenated and deoxygenated blood, showing that blood absorption followed the absorption behavior of haemoglobin and water. The scattering coefficient decreased for wavelengths above 500 nm with approximately λ-1.7; the g factor was higher than 0.9 over the whole wavelength range. © 1999 Society of Photo-Optical Instrumentation Engineers.
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Cited by
Bashkatov, A. N., Genina, E. A., Kochubey, V. I., & Tuchin, V. V. (2005) · Journal of Physics D: Applied Physics · doi:10.1088/0022-3727/38/15/004 · Cited by 1,720
Salomatina, E. V., Jiang, B., Novak, J., & Yaroslavsky, A. N. (2006) · Journal of Biomedical Optics · doi:10.1117/1.2398928 · Cited by 599
A review of in‐vivo optical properties of human tissues and its impact on PDT
Sandell, J. L., & Zhu, T. C. (2011) · Journal of Biophotonics · doi:10.1002/jbio.201100062 · Cited by 384
Oxygen Saturation-Dependent Absorption and Scattering of Blood
Faber, D. J., Aalders, M. C. G., Mik, E. G., Hooper, B. A., van Gemert, M. J. C., & van Leeuwen, T. G. (2004) · Physical Review Letters · doi:10.1103/physrevlett.93.028102 · Cited by 264
O’Brien, K. P., Khan, S., Gilligan, K. E., Zafar, H., Lalor, P., Glynn, C., O’Flatharta, C., Ingoldsby, H., Dockery, P., De Bhulbh, A., et al. (2018) · Oncogene · doi:10.1038/s41388-017-0116-9 · Cited by 215
Metadata
- Authors
- Roggan, A., Friebel, M., Dörschel, K., Hahn, A., & Müller, G.
- Venue
- Journal of Biomedical Optics
- Publisher
- SPIE-Intl Soc Optical Eng
- Published
- 1999
- Volume
- 4
- Issue
- 1
- Pages
- 36
- ISSN
- 1083-3668 (ISSN-L)
- OpenAlex
- W1973846615
- Cited by
- 819
- References
- 11
- FWCI
- 11.85
- Type
- journal article
- Language
- en
- Open access
- bronze
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