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Total attenuation coefficients and scattering phase functions of tissues and phantom materials at 633 nm
Abstract
Measurements have been made of the total attenuation coefficient Σt and the scattering phase function, S(θ), of 632.8 nm of light for a number of animal model tissues, blood, and inert scattering and absorbing media. Polystryrene microspheres of known size and refractive index, for which Σt and S(θ) can be calculated by Mie theory, were used to test the experimental methods. The purpose of the study was to define typical ranges for these optical properties of tissues, as a contribution to the development of experimental and theoretical methods of light dosimetry in tissue, particularly related to photodynamic therapy of solid tumors. The results demonstrate that, for the representative tissues studied, the total attenuation coefficients are of the order of 10–100 mm−1, and that scattering is highly forward peaked, with average cosine of scatter in the range 0.6–0.97.
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Cited by
A review of the optical properties of biological tissues
Cheong, W. F., Prahl, S. A., & Welch, A. J. (1990) · IEEE Journal of Quantum Electronics · doi:10.1109/3.64354 · Cited by 2,530
Patterson, M. S., Chance, B., & Wilson, B. C. (1989) · Applied Optics · doi:10.1364/ao.28.002331 · Cited by 2,087
Self-citationReview of tissue simulating phantoms for optical spectroscopy, imaging and dosimetry
Pogue, B. W., & Patterson, M. S. (2006) · Journal of Biomedical Optics · doi:10.1117/1.2335429 · Cited by 837
Self-citationOptical Properties of Circulating Human Blood in the Wavelength Range 400–2500 nm
Roggan, A., Friebel, M., Dörschel, K., Hahn, A., & Müller, G. (1999) · Journal of Biomedical Optics · doi:10.1117/1.429919 · Cited by 819
Laser Doppler perfusion imaging by dynamic light scattering
Wardell, K., Jakobsson, A., & Nilsson, G. E. (1993) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.222322 · Cited by 435
Metadata
- Authors
- Flock, S. T., Wilson, B. C., & Patterson, M. S.
- Venue
- Medical Physics
- Publisher
- Wiley
- Published
- 1987-09
- Volume
- 14
- Issue
- 5
- Pages
- 835-841
- ISSN
- 0094-2405 (ISSN-L)
- 2473-4209
- OpenAlex
- W2047616560
- Cited by
- 212
- References
- 0
- FWCI
- 12.36
- Type
- journal article
- Language
- en
- Open access
- closed
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- Flock, S. T., Wilson, B. C., & Patterson, M. S. (1987). Total attenuation coefficients and scattering phase functions of tissues and phantom materials at 633 nm. Medical Physics. https://doi.org/10.1118/1.596010
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