Water-Based Aerobic and Resistance Training as A Treatment to Improve the Lipid Profile of Women With Dyslipidemia: A Randomized Controlled Trial
Abstract
Background: Regular exercise is recommended for the treatment of dyslipidemia. The aquatic environment presents some beneficial characteristics for patients suffering from dyslipidemia. However, it is unknown which modality promotes better results. This study aims to compare the effects of water-based aerobic training (WA) and water-based resistance training (WR) on lipid profile of dyslipidemic elderly women. Methods: Sixty-nine dyslipidemic elderly women participated in this 3-arm randomized controlled clinical trial with groups in parallel. The interventions were WA, WR, and control group, with 2 weekly sessions for 10 weeks. Total cholesterol (TC), triglycerides, low-density lipoprotein, high-density lipoprotein (HDL) levels, and TC/HDL ratio, were determined before and after interventions. Results: Intention-to-treat analysis showed that WA and WR participants obtained similar decreases in TC (−10.0% and −9.6%, respectively), triglycerides (−13.4% and −15.7%, respectively), low-density lipoprotein (−16.1% and −16.9%, respectively), TC/HDL (−16.9% and −23.4%, respectively) and increases in HDL (7.6% and 16.9%, respectively). The control group maintained their TC and low-density lipoprotein levels unchanged, whereas triglycerides and TC/HDL were increased (3.6% and 11.3%, respectively), and HDL decreases 4.8%. Conclusions: WA and WR improve similarly the lipid profile of dyslipidemic elderly women, representing interesting nonpharmacological tools in the treatment of dyslipidemia.
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Aquatic-based resistance exercises have shown promising results in improving strength and muscle mass in older individuals and metabolic health in patients with non-communicable diseases.
“In such clinical conditions, aquatic-based resistance exercises could also be a low-impact exercise alternative as they have shown promising results in improving strength and muscle mass in older individuals [141,142], as well as metabolic health in patients with non-communicable diseases [143,144].”
From Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR) (2025) · cites this paper as [144]
Cites
Statistical Power Analysis for the Behavioral Sciences
Muller, K. E., & Cohen, J. (1989) · Technometrics · doi:10.2307/1270020 · Cited by 99,588 · see citing works
Friedewald, W. T., Levy, R. I., & Fredrickson, D. S. (1972) · Clinical Chemistry · doi:10.1093/clinchem/18.6.499 · Cited by 32,423 · see citing works
Jellinger, P. S., Handelsman, Y., Rosenblit, P. D., Bloomgarden, Z. T., Fonseca, V. A., Garber, A. J., Grunberger, G., Guerin, C. K., Bell, D. S. H., Mechanick, J. I., et al. (2017) · Endocrine Practice · doi:10.4158/ep171764.appgl · Cited by 1,094 · see citing works
Lipoprotein ratios: Physiological significance and clinical usefulness in cardiovascular prevention
Muñóz (2009) · Vascular Health and Risk Management · doi:10.2147/vhrm.s6269 · Cited by 756 · see citing works
Response of blood lipids to exercise training alone or combined with dietary intervention
LEON, A. S., & SANCHEZ, O. A. (2001) · Medicine and Science in Sports and Exercise · doi:10.1097/00005768-200106001-00021 · Cited by 662 · see citing works
Blood Lipid and Lipoprotein Adaptations to Exercise: A Quantitative Analysis
Durstine, J. L., Grandjean, P. W., Davis, P. G., Ferguson, M. A., Alderson, N. L., & DuBose, K. D. (2001) · Sports Medicine · doi:10.2165/00007256-200131150-00002 · Cited by 588 · see citing works
Summary estimates of cholesterol used to predict coronary heart disease.
Castelli, W. P., Abbott, R. D., & McNamara, P. (1983) · Circulation · doi:10.1161/01.cir.67.4.730 · Cited by 473 · see citing works
Water-based exercise improves health-related aspects of fitness in older women
TAKESHIMA, N., ROGERS, M. E., WATANABE, E., BRECHUE, W. F., OKADA, A., YAMADA, T., ISLAM, M. M., & HAYANO, J. (2002) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200203000-00024 · Cited by 329 · see citing works
HDL cholesterol: reappraisal of its clinical relevance
März, W., Kleber, M. E., Scharnagl, H., Speer, T., Zewinger, S., Ritsch, A., Parhofer, K. G., von Eckardstein, A., Landmesser, U., & Laufs, U. (2017) · Clinical Research in Cardiology · doi:10.1007/s00392-017-1106-1 · Cited by 275 · see citing works
Kelley, G. A., & Kelley, K. S. (2009) · Preventive Medicine · doi:10.1016/j.ypmed.2008.10.010 · Cited by 263 · see citing works
Natriuretic peptides enhance the oxidative capacity of human skeletal muscle
Engeli, S., Birkenfeld, A. L., Badin, P.-M., Bourlier, V., Louche, K., Viguerie, N., Thalamas, C., Montastier, É., Larrouy, D., Harant, I., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci64526 · Cited by 197 · see citing works
Hepatic lipase and dyslipidemia: interactions among genetic variants, obesity, gender and diet.
Deeb, S. S., Zambon, A., Carr, M. C., Ayyobi, A. F., & Brunzell, J. D. (2003) · Journal of Lipid Research · doi:10.1194/jlr.r200017-jlr200 · Cited by 193 · see citing works
Human Physiology in an Aquatic Environment
Pendergast, D. R., Moon, R. E., Krasney, J. J., et al. (2015) · Comprehensive physiology · doi:10.1002/cphy.c140018 · Cited by 164 · see citing works
The underwater environment: cardiopulmonary, thermal, and energetic demands
Pendergast, D. R., & Lundgren, C. E. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.90984.2008 · Cited by 162 · see citing works
Effects of aquatic resistance training on health and fitness in postmenopausal women
Colado, J. C., Triplett, N. T., Tella, V., Saucedo, P., & Abellán, J. (2009) · European Journal of Applied Physiology · doi:10.1007/s00421-009-0996-7 · Cited by 157 · see citing works
Statin Therapy for Primary Prevention of Cardiovascular Disease
Taylor, F. C., Huffman, M. D., & Ebrahim, S. B. J. (2013) · JAMA · doi:10.1001/jama.2013.281348 · Cited by 141 · see citing works
Volaklis, K. A., Spassis, A. T., & Tokmakidis, S. P. (2007) · American Heart Journal · doi:10.1016/j.ahj.2007.06.029 · Cited by 115 · see citing works
Ahmad, Z. (2014) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2014.02.033 · Cited by 110 · see citing works
Dyslipidemias in the Prevention of Cardiovascular Disease: Risks and Causality
Graham, I. M., Cooney, M. T., Bradley, D., Dudina, A. L., & Reiner, Ž. (2012) · Current Cardiology Reports · doi:10.1007/s11886-012-0313-7 · Cited by 109 · see citing works
The effects of exercise on the lipoprotein subclass profile: A meta-analysis of 10 interventions
Sarzynski, M. A., Burton, J. H., Rankinen, T., Blair, S. N., Church, T. S., Després, J., Hagberg, J. M., Landers‐Ramos, R. Q., Leon, A. S., Mikus, C. R., et al. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.10.018 · Cited by 99 · see citing works
Vertical Ground Reaction Force during Water Exercises Performed at Different Intensities
Alberton, C. L., Tartaruga, M. P., Pinto, S. S., et al. (2013) · International Journal of Sports Medicine · doi:10.1055/s-0032-1331757 · Cited by 67 · see citing works
Effects of immersion water temperature on whole‐body fluid distribution in humans
Stocks, J. M., Patterson, M. J., Hyde, D. E., et al. (2004) · Acta Physiologica Scandinavica · doi:10.1111/j.1365-201x.2004.01302.x · Cited by 62 · see citing works
Ebenbichler, C. F., Laimer, M. W., Kaser, S., Ritsch, A., Sandhofer, A., Weiss, H., Aigner, F., & Patsch, J. R. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000032007.14355.21 · Cited by 62 · see citing works
Comparison of acute cardiovascular responses to water immersion and head-down tilt in humans
Shiraishi, M., Schou, M., Gybel‐Brask, M., et al. (2002) · Journal of Applied Physiology · doi:10.1152/jappl.2002.92.1.264 · Cited by 62 · see citing works
Training Enhances ANP Lipid-Mobilizing Action in Adipose Tissue of Overweight Men
Moro, C., Pillard, F., de Glisezinski, I., Harant, I., Rivière, D., Štich, V., Lafontan, M., Crampes, F., & Berlan, M. (2005) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000170124.51659.52 · Cited by 57 · see citing works
Pathophysiology, Diagnosis, and Management of Dyslipidemia
Gau, G. T., & Wright, R. S. (2006) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2006.03.001 · Cited by 48 · see citing works
Delevatti, R. S., Kanitz, A. C., Alberton, C. L., Marson, E. C., Lisboa, S. C., Pinho, C. D. F., Lovatel, G. A., Korb, A., Bertoldi, K., Macedo, R. C. O., et al. (2015) · Journal of science and medicine in sport · doi:10.1016/j.jsams.2015.10.008 · Cited by 45 · see citing works
Self-citationCardiovascular effects of static carotid baroreceptor stimulation during water immersion in humans
Pump, B., Shiraishi, M., Gabrielsen, A., Bie, P., Christensen, N. J., & Norsk, P. (2001) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2001.280.6.h2607 · Cited by 44 · see citing works
Costa, R. R., Kanitz, A. C., Reichert, T. L., Prado, A. K. G., Coconcelli, L., Buttelli, A. C. K., Pereira, L. F., Masiero, M. P. B., Meinerz, A. P., Conceição, M. O., et al. (2018) · Experimental Gerontology · doi:10.1016/j.exger.2018.04.022 · Cited by 42 · see citing works
Self-citationThe role of cardiorespiratory fitness on plasma lipid levels
Parto, P., Lavie, C. J., Swift, D. L., & Sui, X. (2015) · Expert Review of Cardiovascular Therapy · doi:10.1586/14779072.2015.1092384 · Cited by 40 · see citing works
Gabrielsen, A., Pump, B., Bie, P., et al. (2002) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.2002.00932.x · Cited by 36 · see citing works
Natriuretic Peptides: New Players in Energy Homeostasis
Moro, C., & Smith, S. R. (2009) · Diabetes · doi:10.2337/db09-1335 · Cited by 34 · see citing works
Alberton, C. L., Kanitz, A. C., Pinto, S. S., Antunes, A. H., Finatto, P., Cadore, E. L., & Kruel, L. F. M. (2013) · PubMed · Cited by 31 · see citing works
Self-citationRegulation of atrial natriuretic factor release in man: Effect of water immersion
Gerbes, A., Arendt, R. M., Schnizer, W., et al. (1986) · Journal of Molecular Medicine · doi:10.1007/bf01726920 · Cited by 29 · see citing works
Nagashima, K., Nosé, H., Yoshida, T., et al. (1995) · Journal of Applied Physiology · doi:10.1152/jappl.1995.78.1.217 · Cited by 28 · see citing works
Kasprzak, Z., & Pilaczyńska-Szcześniak, Ł. (2014) · Journal of Human Kinetics · doi:10.2478/hukin-2014-0034 · Cited by 26 · see citing works
Neurohumoral and Metabolic Response to Exercise in Water
Wiesner, S., Birkenfeld, A. L., Engeli, S., Haufe, S., Brechtel, L. M., Wein, J., Hermsdorf, M., Karnahl, B., Berlan, M., Lafontan, M., et al. (2010) · Hormone and Metabolic Research · doi:10.1055/s-0030-1248250 · Cited by 26 · see citing works
Costa, R. R., Pilla, C., Buttelli, A. C. K., Barreto, M. F., Vieiro, P. A., Alberton, C. L., Bracht, C. G., & Kruel, L. F. M. (2018) · Research Quarterly for Exercise and Sport · doi:10.1080/02701367.2018.1441485 · Cited by 25 · see citing works
Self-citationAngiotensin II attenuates the natriuresis of water immersion in humans
Schou, M., Gabrielsen, A., Bruun, N. E., et al. (2002) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00536.2001 · Cited by 20 · see citing works
Fluid-regulating hormones during exercise when central blood volume is increased by water immersion
Sheldahl, L. M., Tristani, F. E., Connelly, T. P., et al. (1992) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1992.262.5.r779 · Cited by 18 · see citing works
Systematic Review of CETP Inhibitors for Increasing High-Density Lipoprotein Cholesterol
Bishop, B. M. (2013) · American Journal of Therapeutics · doi:10.1097/mjt.0b013e31828b8463 · Cited by 14 · see citing works
Yoo, Y., Kim, S.-K., & Song, M.-S. (2013) · Physical Activity and Nutrition · doi:10.5717/jenb.2013.17.4.133 · Cited by 11 · see citing works
Karner-Rezek, K., Knechtle, B., Fenzl, M., Gredig, J., & Rosemann, T. (2013) · Trials · doi:10.1186/1745-6215-14-328 · Cited by 7 · see citing works
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Izquierdo, M., de Souto Barreto, P., Arai, H., Bischoff-Ferrari, H. A., Cadore, E. L., Cesari, M., Chen, L.-K., Coen, P. M., Courneya, K. S., Duque, G., et al. (2025) · The Journal of nutrition, health and aging · doi:10.1016/j.jnha.2024.100401 · Cited by 273 · see citing works
- Authors
- Costa, R. R., Buttelli, A. C. K., Coconcelli, L., Pereira, L. F., Vieira, A. F., Fagundes, A. D. O., Farinha, J. B., Reichert, T., Stein, R., & Kruel, L. F. M.
- ORCID
- Venue
- Journal of Physical Activity and Health
- Publisher
- Human Kinetics
- Published
- 2019-05
- Volume
- 16
- Issue
- 5
- Pages
- 348-354
- ISSN
- 1543-3080 (ISSN-L)
- 1543-5474
- OpenAlex
- W2935705474
- Cited by
- 16
- References
- 43
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 1
- FWCI
- 1.93
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Physical Activity and Health (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Keywords
- aquatic exercise, dyslipidemia, lipid profile, older women, total cholesterol, triglycerides, LDL cholesterol, HDL cholesterol, TC/HDL-C ratio, non-pharmacological treatment
- MeSH terms
- Aged, Female, Humans, Male, Middle Aged, Swimming, Exercise, Dyslipidemias, Resistance Training
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