The Inhibitor Ko143 Is Not Specific for ABCG2

Cited by (157)

Items 101–157 of 157

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2. Mifepristone potentiates etoposide toxicity in Hep G2 cells by modulating drug transport
   Zdeněk Dostál, Pavel Kosina, Petr Mlejnek, K. Kikalová, Martin Modrianský · 2018 · Toxicology in Vitro
3. Inhibitors of ABCG2-mediated multidrug resistance: Lead generation through computer-aided drug design
   Laura Goracci, Alessandra Nurisso, Emile Roussel, Basile Pérès, Vincent Chaptal, Pierre Falson, Christelle Marminon, Joachim Jose, Marc Le Borgne, Ahcène Boumendjel · 2023 · European Journal of Medicinal Chemistry
4. The role of efflux transporters in cytotoxicity and intracellular concentration of chlorpyrifos and chlorpyrifos oxon in human cell lines
   Samira Goldar, George Gachumi, Steven D. Siciliano, Natacha Hogan · 2024 · Toxicology in Vitro
5. Consideration of Metabolite Efflux in Radiolabelled Choline Kinetics
   Yunqing Li, Marianna Inglese, Suraiya Dubash, Chris Barnes, Diana Bričkutė, Marta Costa Braga, Ning Wang, Alice Beckley, Kathrin Heinzmann, Louis Allott et al. · 2021 · Pharmaceutics
6. The History of the ABC Proteins in Human Trypanosomiasis Pathogens
   Kelli Monteiro da Costa, Raphael do Carmo Valente, Leonardo Marques da Fonseca, Leonardo Freire‐de‐Lima, Jose Osvaldo Previato, Lúcia Mendonça‐Previato · 2022 · Pathogens
7. Influence of breast cancer resistance protein and P-glycoprotein on tissue distribution and excretion of Ko143 assessed with PET imaging in mice
   Severin Mairinger, Viktoria Zoufal, Thomas Wanek, Alexander Traxl, Thomas Filip, Michael Sauberer, Johann Stanek, Claudia Kuntner, Jens Pahnke, Markus Müller et al. · 2018 · European Journal of Pharmaceutical Sciences
8. Effect of P-glycoprotein and Cotreatment with Sofosbuvir on the Intestinal Permeation of Tenofovir Disoproxil Fumarate and Tenofovir Alafenamide Fumarate
   Martin Huličiak, Ivona Lhotská, Hana Kocova-Vlckova, Veronika Halodova, Tomáš Dušek, Filip Čečka, František Štaud, Ivan Vokřál, Lukáš Červený · 2023 · Pharmaceutical Research
9. Molecular Determinants for Photodynamic Therapy Resistance and Improved Photosensitizer Delivery in Glioma
   David Aebisher, Paweł Woźnicki, Magdalena Czarnecka–Czapczyńska, Klaudia Dynarowicz, Ewelina Szliszka, Aleksandra Kawczyk‐Krupka, Dorota Bartusik‐Aebisher · 2024 · International Journal of Molecular Sciences
10. Enhancing PDT efficacy in NMIBC: Efflux inhibitor mediated improvement of PpIX levels and efficacy of the combination of PpIX‐PDT and SO‐cleavable prodrugs
    Soniya Kumbham, Kazi Md Mahabubur Rahman, Caroline Bosmajian, Ganesh Bist, Barbara A. Foster, Sukyung Woo, Youngjae You · 2024 · Photochemistry and Photobiology
11. Role of ABC transporters in trans‐epithelial transport of vitamin K antagonists
    Bernadette España, Solange Couturier, Caroline Prouillac · 2016 · Biopharmaceutics & Drug Disposition
12. New players from the old chalcone scaffold: Synthesis, identification, and characterization of new potent ABCG2 inhibitors
    Bruna Estelita Ruginsk, Ingrid Fátima Zattoni, A. H. Oliveira, Isadora da Silva Zanzarini, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Antti Poso, Thales Kronenberger, Katalin Goda, Vivian Rotuno Moure et al. · 2025 · European Journal of Medicinal Chemistry
13. Exposure to anticancer drugs modulates the expression of ACSL4 and ABCG2 proteins in adrenocortical carcinoma cells
    Mayra Agustina Ríos Medrano, María Mercedes Bigi, Paloma Martínez Ponce, Ernesto Jorge Podesta, Ulises Daniel Orlando · 2023 · Heliyon
14. The role of ABC transporters in the human lung epithelium—insights from and limitations of current in vitro cell models
    Silke Simon, Carina Cantrill, Claus‐Michael Lehr · 2025 · In vitro models
15. Practical Synthesis of [18F]Pitavastatin and Evaluation of Hepatobiliary Transport Activity in Rats by Positron Emission Tomography
    Takayoshi Nakaoka, Yuta Uetake, Kenichi Kaneko, Takashi Niwa, Hidenori Ochiai, Satsuki Irie, Yoshie Suezaki, Natsumi Otsuka, Emi Hayashinaka, Yasuhiro Wada et al. · 2020 · Molecular Pharmaceutics
16. Hydroxygenkwanin Improves the Efficacy of Cytotoxic Drugs in ABCG2-Overexpressing Multidrug-Resistant Cancer Cells
    Yanqing Li, Megumi Murakami, Yang-Hui Huang, Tai‐Ho Hung, Shun-Ping Wang, Yu‐Shan Wu, Suresh V. Ambudkar, Chung‐Pu Wu · 2022 · International Journal of Molecular Sciences
17. Imaging of hepatic drug transporters with [131I]6-β-iodomethyl-19-norcholesterol
    Masato Kobayashi, Kodai Nishi, Asuka Mizutani, Tsuzumi Hokama, Miki Matsue, Tetsuya Tsujikawa, Takeo Nakanishi, Ryuichi Nishii, Ikumi Tamai, Keiichi Kawai · 2019 · Scientific Reports
18. Development of prospective non-toxic inhibitors of ABCB1 activity and expression in a series of selenophenoquinolinones
    Jelena Vasiljeva, Marina Makrecka‐Kuka, Илона Домрачева, Kārlis Vilks, Pāvels Dimitrijevs, Pavel Arsenyan · 2022 · New Journal of Chemistry
19. ABCC1/MRP1 exports cGAMP and modulates cGAS-dependent immunity
    Joanna H. Maltbaek, Jessica M. Snyder, Daniel B. Stetson · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
20. Distinctive Labeling of Live Monocytes and Neutrophils with a Single Fluorescent Molecule
    Songhui Kim, Masahiro Fukuda, Jung Yeol Lee, Young‐Tae Chang, Hyunsoo Shawn Je, Beomsue Kim · 2023 · Chemosensors
21. A novel acquired resistance mechanism to 5‐aminolevulinic acid‐mediated photodynamic therapy with ABCG2 inhibition
    Sharayu Chandratre, Jordyn Olsen, Bin Chen · 2025 · Photochemistry and Photobiology
22. The fourth-generation EGFR tyrosine kinase inhibitor BLU-945 resensitizes ABCG2-overexpressing multidrug-resistant non-small cell lung cancer cells to cytotoxic anticancer drugs
    Yen-Ching Li, Bing-Huan Lin, Megumi Murakami, Yu‐Shan Wu, Tai‐Ho Hung, Suresh V. Ambudkar, Chung‐Pu Wu · 2025 · European Journal of Pharmaceutical Sciences
23. Identification of an N-methylpyrazole derivative as a selective inhibitor of breast cancer resistance protein (BCRP/ABCG2)
    Andrezza Braiane Ferreira Siridó, A. H. Oliveira, Julia Poletto, Thales Kronenberger, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Marc Le Borgne, Ahcène Boumendjel, Fernanda A. Rosa, Gláucio Valdameri et al. · 2026 · Archives of Biochemistry and Biophysics
24. Tetrahydro-β-carboline scaffold in drug discovery
    Xin Chen · 2023 · Elsevier eBooks
25. Elucidating the binding specificity of interactive compounds targeting ATP-binding cassette subfamily G member 2 (ABCG2)
    Kumar, Pawan, Kumari, Indu, Prasad, Rajendra, Ray, Shashikant, Banerjee, Atanu, Prakash, Amresh · 2025 · Molecular Diversity
26. A Synthetic Hybrid Molecule for the Selective Removal of Human Pluripotent Stem Cells from Cell Mixtures
    Di Mao, Shin Ando, Shin‐ichi Sato, Ying� Qin, Nao Hirata, Yousuke Katsuda, Eihachiro Kawase, Ting‐Fang Kuo, Itsunari Minami, Yuji Shiba et al. · 2017 · Angewandte Chemie
27. Pharmacologic Inhibition of Ubiquitin Activation as a Novel Therapeutic Strategy in Acute Myeloid Leukemia
    Samir H. Barghout · 2020 · TSpace (University of Toronto)
28. [Role of breast cancer resistance protein in drug disposition].
    Xiangmeng Wu, Sheng Li, Yufei Jia, Yan Li · 2016 · PubMed
29. Multiple Molecular Mechanisms Contribute Towards In Vitro Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukaemia
    Benjamin Chia Sing Leow · 2019 · Adelaide Research & Scholarship (AR&S) (University of Adelaide)
30. In silico assessment of coriander leaf extract active compound to resensitize oxaliplatin resistance in colorectal cancer mediated by ABCG2 and UPF1 proteins
    Sun JESSICA, Sandra B. FILEMON, Sharron SANTOSA, Stephani C. MAHARANI, Arli Aditya Parikesit · 2024 · Notulae Scientia Biologicae
31. Elucidating the role of ABC transporters in the placental efflux of (−)- Δ9-tetrahydrocannabinol (THC) using a cocktail of ABC transport inhibitors
    Ankit Balhara, Xin Chen, Aditya R. Kumar, Morgan E. Wasickanin, Joshua W. Monson, Jennifer R. Damicis, Hillary J. Kinsman, Nicholas M. Ieronimakis, Jashvant D. Unadkat · 2025 · Placenta
32. Rôles des transporteurs ABC dans la variabilité pharmacocinétique des anticoagulants oraux directs : approche in vitro
    Elodie Jacqueroux · 2019 · theses.fr (ABES)
33. Inhibiteurs du transporteur BCRP/ABCG2 impliqué dans la chimiorésistance : conception, synthèse et évaluation biologique
    Emile Roussel · 2019 · theses.fr (ABES)
34. Cytochrome P450–mediated metabolism of K31, a Ko143-derived ATP-binding cassette subfamily G member 2 inhibitor
    Fu‐Ying Qin, Junjie Zhu, Bjoern Brixius, Simone Brixius‐Anderko, Jiaojiao Zhang, Meera Menon, Yixian Huang, Song Li, Xiaochao Ma · 2026 · Drug Metabolism and Disposition
35. Attenuation of ABCG2-dependent drug efflux by befotertinib restores chemosensitivity in multidrug-resistant non-small cell lung cancer cells
    Yen-Ching Li, Ting‐Yu Chen, Hui-Chiau Chuang, Bing-Huan Lin, Megumi Murakami, Yu-Tzu Chang, Yu‐Shan Wu, Tai‐Ho Hung, Suresh V. Ambudkar, Chung‐Pu Wu · 2026 · Biomedicine & Pharmacotherapy
36. Identification of the Acetamide-Chalcone Derivative That Selectively Inhibits ABCG2 Transport Activity
    A. H. Oliveira, Eli Silveira-Alves, Thales Kronenberger, Jean Carlos Pereira Sousa, Bruna Estelita Ruginsk, Katalin Goda, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Vivian Rotuno Moure, Pablo José Gonçalves et al. · 2026 · ACS Omega
37. Effects of ABCG2 knockdown on therapeutic enhancement of 5‐aminolevulinic acid with lapatinib
    Jordyn Wescoat, Corinna Cabral, Bin Chen · 2026 · Photochemistry and Photobiology
38. Re-Evaluating Multi-Kinase Inhibitors Targeting FGFR and VEGFR Pathways for Combined Therapy in Colorectal Cancer: A Preclinical Study
    Sergei Boichuk, Tatyana Gessel, Павел Дмитриевич Дунаев, Галяутдинова Алина Эльвировна, Emiliya S. Egorova, Pavel Kopnin, Андриуца Наталья Сергеевна, Aigul R. Galembikova · 2026 · Cancers
39. BindingDB Entry 50019699: and
    BindingDB · 2024 · UC San Diego
40. BindingDB Entry 50018402: A review of synthetic bioactive tetrahydro-β-carbolines: A medicinal chemistry perspective.
    BindingDB · 2024 · UC San Diego
41. BindingDB Entry 50007021: Triazole Bridged Flavonoid Dimers as Potent, Nontoxic, and Highly Selective Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibitors.
    BindingDB · 2021 · UC San Diego
42. BindingDB Entry 50013888: Discovery of new pyrimidopyrrolizine/indolizine-based derivatives as P-glycoprotein inhibitors: Design, synthesis, cytotoxicity, and MDR reversal activities.
    BindingDB · 2022 · UC San Diego
43. BindingDB Entry 50016463: Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    BindingDB · 2023 · UC San Diego
44. BindingDB Entry 50019120: 9-Deazapurines as Broad-Spectrum Inhibitors of the ABC Transport Proteins P-Glycoprotein, Multidrug Resistance-Associated Protein 1, and Breast Cancer Resistance Protein.
    BindingDB · 2024 · UC San Diego
45. BindingDB Entry 50020246: Inhibitors of ABCG2-mediated multidrug resistance: Lead generation through computer-aided drug design.
    BindingDB · 2024 · UC San Diego
46. BindingDB Entry 50007175: Synthesis and biological evaluation of quinazoline derivatives - A SAR study of novel inhibitors of ABCG2.
    BindingDB · 2021 · UC San Diego
47. BindingDB Entry 50001381: Synthesis and biological investigation of 2,4-substituted quinazolines as highly potent inhibitors of breast cancer resistance protein (ABCG2).
    BindingDB · 2020 · UC San Diego
48. BindingDB Entry 50000024: 4-Anilino-2-pyridylquinazolines and -pyrimidines as Highly Potent and Nontoxic Inhibitors of Breast Cancer Resistance Protein (ABCG2).
    BindingDB · 2019 · UC San Diego
49. BindingDB Entry 50003020: Discovery of Novel Flavonoid Dimers To Reverse Multidrug Resistance Protein 1 (MRP1, ABCC1) Mediated Drug Resistance in Cancers Using a High Throughput Platform with "Click Chemistry".
    BindingDB · 2020 · UC San Diego
50. BindingDB Entry 50001777: 2,4,6-Substituted Quinazolines with Extraordinary Inhibitory Potency toward ABCG2.
    BindingDB · 2020 · UC San Diego
51. BindingDB Entry 50022334: Metabolism-guided development of Ko143 analogs as ABCG2 inhibitors.
    BindingDB · 2025 · UC San Diego
52. BindingDB Entry 50000896: New Inhibitors of Breast Cancer Resistance Protein (ABCG2) Containing a 2,4-Disubstituted Pyridopyrimidine Scaffold.
    BindingDB · 2020 · UC San Diego
53. BindingDB Entry 50017999: Updated chemical scaffolds of ABCG2 inhibitors and their structure-inhibition relationships for future development.
    BindingDB · 2023 · UC San Diego
54. BindingDB Entry 50048041: New, highly potent and non-toxic, chromone inhibitors of the human breast cancer resistance protein ABCG2.
    BindingDB · 2018 · UC San Diego
55. BindingDB Entry 50011813: Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP).
    BindingDB · 2022 · UC San Diego
56. BindingDB Entry 50048219: Phenyltetrazolyl-phenylamides: Substituent impact on modulation capability and selectivity toward the efflux protein ABCG2 and investigation of interaction with the transporter.
    BindingDB · 2018 · UC San Diego
57. BindingDB Entry 50010202: Synthesis and Investigation of Tetrahydro-β-carboline Derivatives as Inhibitors of the Breast Cancer Resistance Protein (ABCG2).
    BindingDB · 2021 · UC San Diego