Therapeutic potential of mood stabilizers lithium and valproic acid:Beyond bipolar disorder

Cites (580)

Items 201–400 of 580

  1. Valproic acid increases SMN levels in spinal muscular atrophy patient cells
    Charlotte J. Sumner, Thanh N. Huynh, Jennifer A. Markowitz, J. Stephen Perhac, Brenna J. Hill, Daniel D. Coovert, Kristie R. Schussler, Xiaocun Chen, Jill Jarecki, Arthur H.M. Burghes et al. · 2003 · Annals of Neurology
  2. Neuroprotective Effects of Regulators of the Glycogen Synthase Kinase-3β Signaling Pathway in a Transgenic Model of Alzheimer's Disease Are Associated with Reduced Amyloid Precursor Protein Phosphorylation
    Edward M. Rockenstein, Magdalena Torrance, Anthony Adame, Michael Mante, Pazit Bar‐On, John Bart Rose, Leslie A. Crews, Eliezer Masliah · 2007 · Journal of Neuroscience
  3. Mental Health Service Utilization by Borderline Personality Disorder Patients and Axis II Comparison Subjects Followed Prospectively for 6 Years
    Zanarini, Mary C., Frankenburg, Frances R., Hennen, John, Silk, Kenneth R. · 2004 · The Journal of Clinical Psychiatry
  4. Cellular Plasticity Cascades: Targets for the Development of Novel Therapeutics for Bipolar Disorder
    Carlos A. Zarate, Jaskaran B. Singh, Husseini K. Manji · 2006 · Biological Psychiatry
  5. Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on β-catenin in mouse hippocampus
    Oksana Kaidanovich‐Beilin, Anat Milman, Abraham Weizman, Chaim G. Pick, Hagit Eldar-Finkelman · 2004 · Biological Psychiatry
  6. α‐Synuclein contributes to GSK‐3β‐catalyzed Tau phosphorylation in Parkinson's disease models
    Tetyana Duka, Valeriy Duka, Jeffrey N. Joyce, Anita Sidhu · 2009 · The FASEB Journal
  7. Understanding microRNAs in neurodegeneration
    Stephen M. Eacker, Ted M. Dawson, Valina Lynn Dawson · 2009 · Nature reviews. Neuroscience
  8. Transcriptional signatures in Huntington's disease
    Jang-Ho J. Cha · 2007 · Progress in Neurobiology
  9. Stem cell technology for neurodegenerative diseases
    J. Simon Lunn, Stacey A. Sakowski, Junguk Hur, Eva L. Feldman · 2011 · Annals of Neurology
  10. National US Estimates of Recombinant Tissue Plasminogen Activator Use
    Dawn Kleindorfer, Christopher John Lindsell, Lawrence M. Brass, Walter J. Koroshetz, Joseph P. Broderick · 2008 · Stroke
  11. Lithium protects cultured neurons against β‐amyloid‐induced neurodegeneration
    Gema Alvarez, Juan Ramón Muñoz-Montaño, Jorgina Satrústegui, Jesús Ávila, Elena Bogónez, Javier Díaz‐Nido · 1999 · FEBS Letters
  12. Lithium Treatment and Risk of Dementia
    Kessing, Lars Vedel, Søndergård, Lars, Forman, Julie Lyng, Andersen, Per Kragh · 2008 · Archives of General Psychiatry
  13. Clusterin: A forgotten player in Alzheimer's disease
    Nuutinen, Tapio, Suuronen, Tiina, Kauppinen, Anu, Salminen, Antero · 2009 · Brain Research Reviews
  14. SDF-1α/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat model
    Ye Wang, Yubin Deng, Guangqian Zhou · 2008 · Brain Research
  15. GSK-3β inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila
    Mudher, A, Shepherd, D, Newman, T A, Mildren, P, Jukes, J P, Squire, A, Mears, A, Berg, S, MacKay, D, Asuni, A A et al. · 2004 · Molecular Psychiatry
  16. Increased gray matter volume in lithium-treated bipolar disorder patients
    Roberto B. Sassi, Mark Nicoletti, Paolo Brambilla, Alan G. Mallinger, Ellen Frank, David J. Kupfer, Matcheri S. Keshavan, Jair C. Soares · 2002 · Neuroscience Letters
  17. The NeurotroDhins BDNF, NT‐3 and NT‐4/5 Promote Survival and Morphological and Biochemical Differentiation of Striatal Neurons In Vitro
    Roseann Ventimiglia, Pamela E. Mather, Bruce Edward Jones, Ronald M. Lindsay · 1995 · European Journal of Neuroscience
  18. Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity
    Chen, P.S., Wang, C.-C., Bortner, C.D., Peng, G.-S., Wu, X., Pang, H., Lu, R.-B., Gean, P.-W., Chuang, D.-M., Hong, J.-S. · 2007 · Neuroscience
  19. Biochemical interactions in the wnt pathway
    Martin J. Seidensticker, Jürgen Behrens · 2000 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  20. Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: An essential step for neuroprotection against glutamate excitotoxicity
    Ryota Hashimoto, Nobuyuki Takei, Kazuhiro Shimazu, Lori A. Christ, Bai Lu, De‐Maw Chuang · 2002 · Neuropharmacology
  21. Post-menopausal oestrogen therapy.
    Richard J. Lindsay · 1979 · PubMed
  22. Upregulation of Dicer and MicroRNA Expression in the Dorsolateral Prefrontal Cortex Brodmann Area 46 in Schizophrenia
    Danielle M. Santarelli, Natalie Jane Beveridge, Paul A. Tooney, Murray J. Cairns · 2010 · Biological Psychiatry
  23. Pharmacological Inhibition of Histone Deacetylases by Suberoylanilide Hydroxamic Acid Specifically Alters Gene Expression and Reduces Ischemic Injury in the Mouse Brain
    Giuseppe Faraco, Tristano Pancani, Laura Formentini, Paolo Mascagni, Gianluca Fossati, Flavio Leoni, Flavio Moroni, Alberto Chiarugi · 2006 · Molecular Pharmacology
  24. Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats
    Shigeyuki Nonaka, De‐Maw Chuang · 1998 · Neuroreport
  25. Altered MicroRNA Expression Profiles in Postmortem Brain Samples from Individuals with Schizophrenia and Bipolar Disorder
    Moreau, Michael P., Bruse, Shannon E., David-Rus, Richard, Buyske, Steven, Brzustowicz, Linda M. · 2011 · Biological Psychiatry
  26. Lithium-Induced Gray Matter Volume Increase As a Neural Correlate of Treatment Response in Bipolar Disorder: A Longitudinal Brain Imaging Study
    In Kyoon Lyoo, Stephen R. Dager, Jieun E. Kim, Sujung J. Yoon, Seth D. Friedman, David L. Dünner, Perry Franklin Renshaw · 2010 · Neuropsychopharmacology
  27. Acceleration and Augmentation of Antidepressants With Lithium for Depressive Disorders: Two Meta-Analyses of Randomized, Placebo-Controlled Trials
    Crossley, Nicolas Andres, Bauer, Michael · 2007 · The Journal of Clinical Psychiatry
  28. Specification of the Neurobehavioral Phenotype in Males with Fragile X Syndrome
    Thomas L. Baumgardner, Allan L. Reiss, Lisa S. Freund, Michael T. Abrams · 1995 · PEDIATRICS
  29. Widespread Disruption of Repressor Element-1 Silencing Transcription Factor/Neuron-Restrictive Silencer Factor Occupancy at Its Target Genes in Huntington's Disease
    Zuccato, C., Belyaev, N., Conforti, P., Ooi, L., Tartari, M., Papadimou, E., MacDonald, M., Fossale, E., Zeitlin, S., Buckley, N. et al. · 2007 · Journal of Neuroscience
  30. Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease
    Ricobaraza, Ana, Cuadrado‐Tejedor, Mar, Marco, Sonia, Pérez‐Otaño, Isabel, García‐Osta, Ana · 2012 · Hippocampus
  31. Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers
    Todd D. Gould, Jorge A. Quiroz, Jaskaran B. Singh, Carlos A. Zarate, H.K. Manji · 2004 · Molecular Psychiatry
  32. A Longitudinal Study of the Effects of Lithium Treatment on Prefrontal and Subgenual Prefrontal Gray Matter Volume in Treatment-Responsive Bipolar Disorder Patients
    Moore, Gregory J., Cortese, Bernadette M., Glitz, Debra A., Zajac-Benitez, Caroline, Quiroz, Jorge A., Uhde, Thomas W., Drevets, Wayne C., Manji, Husseini K. · 2009 · The Journal of Clinical Psychiatry
  33. Inactivation of Glycogen Synthase Kinase 3 Promotes Axonal Growth and Recovery in the CNS
    John Dill, Hongyu Wang, Feng‐Quan Zhou, Shuxin Li · 2008 · Journal of Neuroscience
  34. Valproic Acid Attenuates Blood–Brain Barrier Disruption in a Rat Model of Transient Focal Cerebral Ischemia: The Roles of HDAC and MMP-9 Inhibition
    Zhifei Wang, Yan Leng, Li‐Kai Tsai, Peter R. Leeds, De‐Maw Chuang · 2010 · Journal of Cerebral Blood Flow & Metabolism
  35. Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model
    Honglin Feng, Yan Leng, Cong Ma, Jinzhi Zhang, Ming Ren, D M Chuang · 2008 · Neuroscience
  36. Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders
    Chi‐Tso Chiu, De‐Maw Chuang · 2010 · Pharmacology & Therapeutics
  37. Untitled work
    2011 · 10.2165/11586970-000000000-00000
  38. Novel Insights into Lithium’s Mechanism of Action: Neurotrophic and Neuroprotective Effects
    Jorge A. Quiroz, Rodrigo Machado‐Vieira, Carlos A. Zarate, Husseini K. Manji · 2010 · Neuropsychobiology
  39. Anti-Inflammatory Effects of the 70 kDa Heat Shock Protein in Experimental Stroke
    Zhen Zheng, Jong Youl Kim, Hualong Ma, Jong Eun Lee, Midori Anne Yenari · 2007 · Journal of Cerebral Blood Flow & Metabolism
  40. Chronic Divalproex Sodium to Attenuate Agitation and Clinical Progression of Alzheimer Disease
    Pierre N. Tariot · 2011 · Archives of General Psychiatry
  41. Lithium levels in drinking water and risk of suicide
    Hirochika Ohgami, Takeshi Terao, Ippei Shiotsuki, Nobuyoshi Ishii, Noboru Iwata · 2009 · The British Journal of Psychiatry
  42. In Vivo Evidence in the Brain for Lithium Inhibition of Glycogen Synthase Kinase-3
    Todd D. Gould, Guang Jing Chen, Husseini K. Manji · 2003 · Neuropsychopharmacology
  43. Phosphorylation of paired helical filament tau in Alzheimer's disease neurofibrillary lesions: focusing on phosphatases.
    John Q. Trojanowski, V M Lee · 1995 · The FASEB Journal
  44. Multiphasic roles for matrix metalloproteinases after stroke
    ROSELL, A, LO, E · 2008 · Current Opinion in Pharmacology
  45. Synergistic Neuroprotective Effects of Lithium and Valproic Acid or Other Histone Deacetylase Inhibitors in Neurons: Roles of Glycogen Synthase Kinase-3 Inhibition
    Yan Leng, Min‐Huei Liang, Ming Ren, Zoya Marinova, Peter R. Leeds, De‐Maw Chuang · 2008 · Journal of Neuroscience
  46. Motor Deficit in a Drosophila Model of Mucolipidosis Type IV due to Defective Clearance of Apoptotic Cells
    Kartik Venkatachalam, Ashleigh Long, Rebecca S. Elsaesser, Daria Nikolaeva, Kendal S. Broadie, Craig Montell · 2008 · Cell
  47. Open-Label Treatment Trial of Lithium to Target the Underlying Defect in Fragile X Syndrome
    Berry-Kravis, Elizabeth, Sumis, Allison, Hervey, Crystal, Nelson, Michael, Porges, Stephen W., Weng, Ning, Weiler, Ivan Jeanne, Greenough, William T. · 2008 · Journal of Developmental & Behavioral Pediatrics
  48. Sodium Valproate Exerts Neuroprotective EffectsIn Vivothrough CREB-Binding Protein-Dependent Mechanisms But Does Not Improve Survival in an Amyotrophic Lateral Sclerosis Mouse Model
    Caroline Rouaux, Irina Panteleeva, Frédérique René, José‐Luis González de Aguilar, Andoni Echaniz‐Laguna, Luc Dupuis, Yannick Menger, Anne‐Laurence Boutillier, Jean‐Philippe Loeffler · 2007 · Journal of Neuroscience
  49. Bilateral hippocampal volume increases after long-term lithium treatment in patients with bipolar disorder: a longitudinal MRI study
    Kaan Yücel, Margaret C. McKinnon, Valerie H. Taylor, Kathryn Macdonald, Martin Alda, Lionel Trevor Young, GLENDA M. MacQUEEN · 2007 · Psychopharmacology
  50. Benefit of valproic acid in suppressing disease progression of ALS model mice
    Fuminobu Sugai, Yoichi Yamamoto, Katsuyuki Miyaguchi, Zhiwei Zhou, Hisae Sumi, Toshimitsu Hamasaki, Masashi Goto, Saburo Sakoda · 2004 · European Journal of Neuroscience
  51. Bilateral Hippocampal Volume Increase in Patients with Bipolar Disorder and Short-term Lithium Treatment
    Kaan Yücel, Valerie H. Taylor, Margaret C. McKinnon, Kathryn Macdonald, Martin Alda, Lionel Trevor Young, GLENDA M. MacQUEEN · 2007 · Neuropsychopharmacology
  52. Identification of New Genetic Risk Variants for Type 2 Diabetes
    Xiao Ou Shu, Jirong Long, Qiuyin Cai, Lu Qi, Yong‐Bing Xiang, Yoon Shin Cho, E Shyong Tai, Xiangyang Li, Lin Xu, Wong‐Ho Chow et al. · 2010 · PLoS Genetics
  53. Inflammation Induced by Infection Potentiates Tau Pathological Features in Transgenic Mice
    Sy, Michael, Kitazawa, Masashi, Medeiros, Rodrigo, Whitman, Lucia, Cheng, David, Lane, Thomas E., LaFerla, Frank M. · 2011 · The American Journal of Pathology
  54. GSK3 Influences Social Preference and Anxiety-Related Behaviors during Social Interaction in a Mouse Model of Fragile X Syndrome and Autism
    Marjelo A. Mines, Christopher J. Yuskaitis, Margaret K. King, Eléonore Beurel, Richard Scott Jope · 2010 · PLoS ONE
  55. Alteration in Kinase Activity But Not in Protein Levels of Protein Kinase B and Glycogen Synthase Kinase-3β in Ventral Prefrontal Cortex of Depressed Suicide Victims
    Félicien Karege, Nader Ali Perroud, Sandra Burkhardt, Michèle Schwald, Eladia Ballmann, Romano La Harpe, Alain Malafosse · 2006 · Biological Psychiatry
  56. GDNF and GFRα: a versatile molecular complex for developing neurons
    Gustavo Paratcha, Fernanda Ledda · 2008 · Trends in Neurosciences
  57. MOLECULAR EFFECTS of lithium
    J. A. Quiroz · 2004 · Molecular Interventions
  58. Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model
    Ming Ren, Vladimir V. Senatorov, Ren‐Wu Chen, De‐Maw Chuang · 2003 · Proceedings of the National Academy of Sciences
  59. 3-Nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorder
    Ana C. Andreazza, Flávio Pereira Kapczinski, Marcia Kauer‐Sant’Anna, Júlio Cesar Walz, David J. Bond, Carlos Alberto Gonçalves, Lionel Trevor Young, Lakshmi N. Yatham · 2009 · Journal of Psychiatry and Neuroscience
  60. Apoptosis in Huntington's disease
    Miriam Ann Hickey, Marie-Françoise Chesselet · 2003 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  61. Mutant Huntingtin Enhances Excitotoxic Cell Death
    Melinda M. Zeron, Nansheng Chen, Ali Moshaver, Allen Ting Chun Lee, Cheryl Lea Wellington, Michael R. Hayden, Lynn A. Raymond · 2001 · Molecular and Cellular Neuroscience
  62. Inhibition of Protein Phosphatase 2A Overrides Tau Protein Kinase I/Glycogen Synthase Kinase 3β and Cyclin-dependent Kinase 5 Inhibition and Results in Tau Hyperphosphorylation in the Hippocampus of Starved Mouse
    Emmanuel Planel, Kaori Yasutake, Shinobu C. Fujita, Koichi Ishiguro · 2001 · Journal of Biological Chemistry
  63. Active HSF1 Significantly Suppresses Polyglutamine Aggregate Formation in Cellular and Mouse Models
    Mitsuaki Fujimoto, Eiichi Takaki, Tetsuya Hayashi, Yasushi Kitaura, Yasunori Tanaka, Sachiye Inouye, Akira Nakai · 2005 · Journal of Biological Chemistry
  64. Lithium neuroprotection: molecular mechanisms and clinical implications
    Michael K. Rowe, De‐Maw Chuang · 2004 · Expert Reviews in Molecular Medicine
  65. Safety and efficacy of lithium in combination with riluzole for treatment of amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial
    Aggarwal, Swati P, Zinman, Lorne, Simpson, Elizabeth, McKinley, Jane, Jackson, Katherine E, Pinto, Hanika, Kaufman, Petra, Conwit, Robin A, Schoenfeld, David, Shefner, Jeremy et al. · 2010 · The Lancet Neurology
  66. Glycogen Synthase Kinase-3β Inhibitors Prevent Cellular Polyglutamine Toxicity Caused by the Huntington’s Disease Mutation
    Jenny Carmichael, Katherine L. Sugars, Yi Ping Bao, David Chaim Rubinsztein · 2002 · Journal of Biological Chemistry
  67. Reduced left anterior cingulate volumes in untreated bipolar patients
    Roberto B. Sassi, Paolo Brambilla, John P. Hatch, Mark Nicoletti, Alan G. Mallinger, Ellen Frank, David J. Kupfer, Matcheri S. Keshavan, Jair C. Soares · 2004 · Biological Psychiatry
  68. On the excitotoxic properties of quinolinic acid, 2,3-piperidine dicarboxylic acids and structurally related compounds
    Alan C. Foster · 1983 · Neuropharmacology
  69. Valproate Administered after Traumatic Brain Injury Provides Neuroprotection and Improves Cognitive Function in Rats
    Pramod K. Dash, Sara A. Orsi, Min Zhang, Raymond J. Grill, Shibani Pati, Jing Zhao, Anthony N. Moore · 2010 · PLoS ONE
  70. Lithium regulates adult hippocampal progenitor development through canonical Wnt pathway activation
    Eric Wexler, Daniel H. Geschwind, Theo D. Palmer · 2007 · Molecular Psychiatry
  71. Behavioural abnormalities contribute to functional decline in Huntington's disease
    Joanne M. Hamilton · 2002 · Journal of Neurology Neurosurgery & Psychiatry
  72. MicroRNA-134 plasma levels before and after treatment for bipolar mania
    Han Rong, Tie Bang Liu, Kong Jun Yang, Hai Chen Yang, Dong Wu, Chun-ping Liao, Fei Hong, He Zen Yang, Feng Wan, Xiao Ying Ye et al. · 2010 · Journal of Psychiatric Research
  73. The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system
    Luca Maria Neri, Paola Borgatti, Silvano Capitani, Alberto Maria Martelli · 2002 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  74. Lithium induces clearance of protease resistant prion protein in prion‐infected cells by induction of autophagy
    Andreas Heiseke, Yasmine Aguib, Constanze Riemer, Michael Baier, Hermann M. Schätzl · 2009 · Journal of Neurochemistry
  75. Oxidative stress parameters in plasma of Huntington's disease patients, asymptomatic Huntington’s disease gene carriers and healthy subjects
    N. Klepac, Maja Relja, R. Klepac, Silva Katusic Hecimovic, Tomislav Babić, Vladimir Trkulja · 2007 · Journal of Neurology
  76. Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse model
    Mar Pérez, Félix Hernández, Filip Lim, Javier Díaz‐Nido, Jesús Ávila · 2003 · Journal of Alzheimer s Disease
  77. Glucose Regulated Protein 78 Diminishes α-Synuclein Neurotoxicity in a Rat Model of Parkinson Disease
    Marina S. Gorbatyuk, Arseniy E. Shabashvili, Weijun Chen, Craig Meyers, Layla F Sullivan, Max Salganik, Jonathan H. Lin, Alfred S. Lewin, Nicholas Muzyczka, Oleg S. Gorbatyuk · 2012 · Molecular Therapy
  78. AAV-Mediated gene delivery of BDNF or GDNF is neuroprotective in a model of huntington disease
    Adrian P. Kells, Dahna M. Fong, Mike Dragunow, Matthew J. During, Deborah Young, Bronwen J. Connor · 2004 · Molecular Therapy
  79. Lithium Increases Transcription Factor Binding to AP‐1 and Cyclic AMP‐Responsive Element in Cultured Neurons and Rat Brain
    Naoko Ozaki, De‐Maw Chuang · 1997 · Journal of Neurochemistry
  80. Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3β and attenuated by lithium
    Taj D. King, Gautam N. Bijur, Richard Scott Jope · 2001 · Brain Research
  81. Abnormalities in brain structure and behavior in GSK-3alpha mutant mice
    Oksana Kaidanovich‐Beilin, Tatiana V. Lipina, Keizo Takao, Matthijs van Eede, Satoko Hattori, Christine L. Laliberté, Mustafa Khan, Kenichi Okamoto, John W Chambers, Paul J. Fletcher et al. · 2009 · Molecular Brain
  82. Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activation
    Dong-In Sinn, Se-Jeong Kim, Kon Chu, Keun‐Hwa Jung, Soon‐Tae Lee, Eun‐Cheol Song, Jeong‐Min Kim, Dong-Kyu Park, Sang Kun Lee, Manho Kim et al. · 2007 · Neurobiology of Disease
  83. Inhibition of GSK-3 Ameliorates Aβ Pathology in an Adult-Onset Drosophila Model of Alzheimer's Disease
    Sofola, Oyinkan, Kerr, Fiona, Rogers, Iain, Killick, Richard, Augustin, Hrvoje, Gandy, Carina, Allen, Marcus J., Hardy, John, Lovestone, Simon, Partridge, Linda · 2010 · PLoS Genetics
  84. Lithium: Bipolar disorder and neurodegenerative diseases Possible cellular mechanisms of the therapeutic effects of lithium
    Frederic Mármol · 2008 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  85. Glycogen Synthase Kinase-3 in the Etiology and Treatment of Mood Disorders
    Richard Scott Jope · 2011 · Frontiers in Molecular Neuroscience
  86. Valproic Acid is Neuroprotective in the Rotenone Rat Model of Parkinson’s Disease: Involvement of α-Synuclein
    Barbara Monti, Valentina Gatta, Francesca Piretti, Simonetta S. Raffaelli, Marco Virgili, Antonio Contestabile · 2009 · Neurotoxicity Research
  87. Inositol and IP3 Levels Regulate Autophagy—Biology and Therapeutic Speculations
    Sovan Sarkar, David Chaim Rubinsztein · 2005 · Autophagy
  88. GSK-3 as a Target for Lithium-Induced Neuroprotection Against Excitotoxicity in Neuronal Cultures and Animal Models of Ischemic Stroke
    De‐Maw Chuang, Zhifei Wang, Chi‐Tso Chiu · 2011 · Frontiers in Molecular Neuroscience
  89. Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia
    Giia-Sheun Peng, Guorong Li, Nian‐Sheng Tzeng, Po-See Chen, De‐Maw Chuang, Yaw‐Don Hsu, Sufen Yang, Jau‐Shyong Hong · 2004 · Molecular Brain Research
  90. The mood stabilizer valproic acid stimulates GABA neurogenesis from rat forebrain stem cells
    Pascal Laeng, Richard L. Pitts, Andrew L. Lemire, Christopher E. Drabik, Arin Weiner, Haiping Tang, Rathi Thyagarajan, Barbara S. Mallon, C. Anthony Altar · 2004 · Journal of Neurochemistry
  91. Intracerebral Peripheral Blood Stem Cell (CD34+) Implantation Induces Neuroplasticity by Enhancing β1 Integrin-Mediated Angiogenesis in Chronic Stroke Rats
    Woei‐Cherng Shyu, Shinn‐Zong Lin, Ming‐Fu Chiang, Ching-Yuan Su, Hung Li · 2006 · Journal of Neuroscience
  92. Vascular Endothelial Growth Factor Overexpression Delays Neurodegeneration and Prolongs Survival in Amyotrophic Lateral Sclerosis Mice
    Yaoming Wang, Xiao Ou Mao, Lin Xie, Surita Banwait, Hugo H. Marti, David A. Greenberg, Kunlin Jin · 2007 · Journal of Neuroscience
  93. Chronic Treatment With a Low Dose of Lithium Protects the Brain Against Ischemic Injury by Reducing Apoptotic Death
    Jihong Xu, Juraj Čulman, Annegret Blume, Stephan Brecht, Peter Gohlke · 2003 · Stroke
  94. Social Cognition Impairments in Relation to General Cognitive Deficits, Injury Severity, and Prefrontal Lesions in Traumatic Brain Injury Patients
    Jacoba Margje Spikman, Marieke E. Timmerman, Maarten V. Milders, Wencke S. Veenstra, Joukje van der Naalt · 2011 · Journal of Neurotrauma
  95. Fetal valproate syndrome.
    Jill Clayton‐Smith, Dian Donnai · 1995 · Journal of Medical Genetics
  96. HIV‐1 Tat‐Mediated Activation of Glycogen Synthase Kinase‐3β Contributes to Tat‐Mediated Neurotoxicity
    Sanjay B. Maggirwar, Ning Tong, Servio H. Ramirez, Harris A. Gelbard, Stephen Dewhurst · 1999 · Journal of Neurochemistry
  97. Brain-Derived Neurotrophic Factor-Mediated Protection of Striatal Neurons in an Excitotoxic Rat Model of Huntington's Disease, as Demonstrated by Adenoviral Gene Transfer
    Alexis‐Pierre Bemelmans, Philippe Horellou, Laurent Pradier, Isabelle Brunet, Philippe Colin, Jacques J. Mallet · 1999 · Human Gene Therapy
  98. microRNAs in neurons: manifold regulatory roles at the synapse
    Gabriele Siegel, Reuben Saba, Gerhard M. Schratt · 2011 · Current Opinion in Genetics & Development
  99. Lithium Therapy Improves Neurological Function and Hippocampal Dendritic Arborization in a Spinocerebellar Ataxia Type 1 Mouse Model
    Kei Watase, Jennifer R. Gatchel, Yaling Sun, Effat S. Emamian, Richard Atkinson, Ronald Richman, Hidehiro Mizusawa, Harry T. Orr, Chad A. Shaw, Huda Yahya Zoghbi · 2007 · PLoS Medicine
  100. Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100
    Xiaoyan Sun, Shinji Sato, Ohoshi Murayama, M. Murayama, J.-M. Park, H. Yamaguchi, Akihiko Takashima · 2002 · Neuroscience Letters
  101. Three-Dimensional Mapping of Hippocampal Anatomy in Unmedicated and Lithium-Treated Patients with Bipolar Disorder
    Carrie E. Bearden, Paul M. Thompson, Rebecca A. Dutton, Benicio Noronha Frey, Marco Aurélio Monteiro Peluso, Mark Nicoletti, Nicole A. Dierschke, Kiralee M. Hayashi, Andrea D. Klunder, David C. Glahn et al. · 2007 · Neuropsychopharmacology
  102. Lithium ameliorates phenotypic deficits in a mouse model of fragile X syndrome
    Zhonghua Liu, De‐Maw Chuang, Carolyn Beebe Smith · 2010 · The International Journal of Neuropsychopharmacology
  103. A feasibility and tolerability study of lithium in Alzheimer's disease
    Alastair Macdonald, Kate Briggs, Michaela Poppe, Andrea R. Higgins, Latha Velayudhan, Simon Lovestone · 2008 · International Journal of Geriatric Psychiatry
  104. Increase of BDNF Serum Concentration in Lithium Treated Patients with Early Alzheimer's Disease
    Thomas Leyhe, Gerhard Wilhelm Eschweiler, Elke Stransky, Thomas Gasser, Peter Annas, Hans Basun, Christoph Laske · 2009 · Journal of Alzheimer s Disease
  105. Valproic acid promotes neuronal differentiation by induction of proneural factors in association with H4 acetylation
    In Tag Yu, Jin-Yong Park, Sung Hyun Kim, Jeong-Sik Lee, Yong-Seok Kim, Hyeon Son · 2008 · Neuropharmacology
  106. Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor in a rat model of depression
    Angelucci, Francesco, Aloe, Luigi, Jiménez-Vasquez, Patricia, Mathé, Aleksander A. · 2003 · The International Journal of Neuropsychopharmacology
  107. Wnt Signaling Regulates the Invasion Capacity of Human Mesenchymal Stem Cells
    Peter Neth, Marisa Karow, Virginia Egea, Juergen Hoelters, Marianne Jochum, Christian Ries · 2006 · Stem Cells
  108. Valproic Acid, a Molecular Lead to Multiple Regulatory Pathways
    Marta Kostrouchová, Z Kostrouch, Marta Kostrouchová · 2007 · Folia Biologica
  109. Transcription, translation and fragile X syndrome
    Kathryn B. Garber, Karen T. Smith, Daniel Reines, Stephen T. Warren · 2006 · Current Opinion in Genetics & Development
  110. Elevated glycogen synthase kinase-3 activity in Fragile X mice: Key metabolic regulator with evidence for treatment potential
    Min, Wenzhong William, Yuskaitis, Christopher J., Yan, Qijiang, Sikorski, Christopher, Chen, Shengqiang, Jope, Richard S., Bauchwitz, Robert P. · 2009 · Neuropharmacology
  111. Lithium increases plasma brain-derived neurotrophic factor in acute bipolar mania: A preliminary 4-week study
    RAFAEL TEIXEIRA DE SOUSA, Martinus Theodorus van de Bilt, Breno Satler Diniz, Rodolfo Braga Ladeira, Luis Valmor Portela, Diogo Onofre Souza, Orestes Vicente Forlenza, Wagner F. Gattaz, Rodrigo Machado‐Vieira · 2011 · Neuroscience Letters
  112. Predictors of nursing home placement in Huntington disease
    Victoria Wheelock, Teresa Tempkin, Karen S. Marder, MARTHA A. NANCE, Richard H. Myers, H. Zhao, Elise Kayson, Constance Orme, Ira Shoulson, the Huntington Study Group · 2003 · Neurology
  113. Histone deactylase inhibition combined with behavioral therapy enhances learning and memory following traumatic brain injury
    Pramod K. Dash, Sara A. Orsi, Amanda Moore · 2009 · Neuroscience
  114. Opposing Actions of Phosphatidylinositol 3‐Kinase and Glycogen Synthase Kinase‐3β in the Regulation of HSF‐1 Activity
    Gautam N. Bijur, Richard Scott Jope · 2000 · Journal of Neurochemistry
  115. Lithium Prevents and Ameliorates Experimental Autoimmune Encephalomyelitis
    Patrizia De Sarno, Robert C. Axtell, Chander Raman, Kevin Aaron Roth, Dario R. Alessi, Richard Scott Jope · 2008 · The Journal of Immunology
  116. Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: Impact of past episodes
    HALUK ASUMAN SAVAS, Hasan Serdar Gergerlioğlu, Ferah Armutçu, Hasan Herken, H. Ramazan Yılmaz, Esra Koçoğlu, Salih Selek, Hamdi Tutkun, Süleyman Salih Zoroğlu, Ömer Akyol · 2006 · The World Journal of Biological Psychiatry
  117. GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder
    Michael K. Rowe, Charlotte Wiest, De‐Maw Chuang · 2007 · Neuroscience & Biobehavioral Reviews
  118. Ebola virus: new insights into disease aetiopathology and possible therapeutic interventions
    Thomas W. Geisbert, Lisa E. Hensley · 2004 · Expert Reviews in Molecular Medicine
  119. Combined Treatment with the Mood Stabilizers Lithium and Valproate Produces Multiple Beneficial Effects in Transgenic Mouse Models of Huntington's Disease
    Chi‐Tso Chiu, Guangping Liu, Peter R. Leeds, De‐Maw Chuang · 2011 · Neuropsychopharmacology
  120. Suicide risk in Huntington's disease.
    Luigi Di Maio, Ferdinando Squitieri, G Napolitano, Giuseppe Campanella, James A. Trofatter, P. Michael Conneally · 1993 · Journal of Medical Genetics
  121. Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease
    Wenzhen Duan, Qi Peng, Naoki Masuda, Eric Ford, Erik J. Tryggestad, Bruce Ladenheim, Ming Zhao, Jean Lud Cadet, John Wong, Christopher A. Ross · 2008 · Neurobiology of Disease
  122. Lithium Ameliorates Neurodegeneration, Suppresses Neuroinflammation, and Improves Behavioral Performance in a Mouse Model of Traumatic Brain Injury
    Fengshan Yu, Zhifei Wang, Flaubert Tchantchou, Chi‐Tso Chiu, Yumin Zhang, De‐Maw Chuang · 2011 · Journal of Neurotrauma
  123. HDAC inhibitor increases histone H3 acetylation and reduces microglia inflammatory response following traumatic brain injury in rats.
    Bin Zhang, E. West, Ken C. Van, Gene G. Gurkoff, Jia Zhou, Xiu-Mei Zhang, A. Kozikowski, Bruce G. Lyeth · 2008 · Brain Research
  124. The Wnt/β-Catenin Signaling Pathway as a Target in Drug Discovery
    Fumi Takahashi‐Yanaga, Toshiyuki Sasaguri · 2007 · Journal of Pharmacological Sciences
  125. Lithium reduces apoptosis and autophagy after neonatal hypoxia–ischemia
    Q Li, Huiqi Li, Karolina Roughton · 2010 · Cell Death and Disease
  126. Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington’s disease
    Huafeng Wei, Zheng‐Hong Qin, Vladimir V. Senatorov, Wenlin Wei, Y Wang, Yanning Qian, D M Chuang · 2001 · Neuroscience
  127. β-Catenin Overexpression in the Mouse Brain Phenocopies Lithium-Sensitive Behaviors
    Todd D. Gould, Haim Einat, Kelley C. O’Donnell, Alyssa M. Picchini, Robert J. Schloesser, Husseini K. Manji · 2007 · Neuropsychopharmacology
  128. Lithium Plus Valproate Combination Therapy Versus Monotherapy for Relapse Prevention in Bipolar I Disorder (BALANCE): A Randomised Open-Label Trial
    The BALANCE investigators and collaborators, John Richard Geddes, Guy M. Goodwin, Jennifer Rendell, Azorin Jm, Andrea Cipriani, Michael Joshua Ostacher, Richard Keith Morriss, Nicola C. Alder, Ed Juszczak · 2011 · FOCUS The Journal of Lifelong Learning in Psychiatry
  129. The Turn Motif Is a Phosphorylation Switch That Regulates the Binding of Hsp70 to Protein Kinase C
    Tianyan Gao, Alexandra C. Newton · 2002 · Journal of Biological Chemistry
  130. Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors
    Diviya Sinha, Zhiyong Wang, Kathleen L. Ruchalski, Jerrold S. Levine, Selvi Krishnan, Wilfred Lieberthal, John H. Schwartz, Steven C. Borkan · 2004 · American Journal of Physiology-Renal Physiology
  131. Chapter 26 Role of Akt and Erk Signaling in the Neurogenesis Following Brain Ischemia
    Norifumi Shioda, Feng Han, Kohji Fukunaga · 2009 · International review of neurobiology
  132. Treatment with lithium carbonate does not improve disease progression in two different strains of SOD1 mutant mice
    Chiara Pizzasegola, Ilaria Caron, Cristina Daleno, Anna Ronchi, Claudio Minoia, Maria Teresa Carrı̀, Caterina Bendotti · 2009 · Amyotrophic Lateral Sclerosis
  133. Antidepressant-like effect of the novel thiadiazolidinone NP031115 in mice
    Angelo Oscar Rosa, Manuella Pinto Kaster, Ricardo W. Binfaré, Susana Morales, Ester Martı́n-Aparicio, Marı́a Luisa Navarro-Rico, Ana Martı́nez, Miguel Medina, Antonio G. Garcı́a, Manuela G. López et al. · 2008 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  134. Valproic acid attenuates blood–spinal cord barrier disruption by inhibiting matrix metalloprotease‐9 activity and improves functional recovery after spinal cord injury
    Jee Y. Lee, Hwang S. Kim, Hye Young Choi, Tae H. Oh, Bong Gun Ju, Tae Young Yune · 2012 · Journal of Neurochemistry
  135. Valproic Acid–Mediated Neuroprotection and Regeneration in Injured Retinal Ganglion Cells
    Julia Biermann, Philippe Grieshaber, Ulrich Goebel, Gottfried Martin, Solon Thanos, Simone Di Giovanni, Wolf Alexander Lagrèze · 2010 · Investigative Ophthalmology & Visual Science
  136. Valproic acid induces functional heat‐shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation
    Zoya Marinova, Ming Ren, Jens R. Wendland, Yan Leng, Min‐Huei Liang, Shigeru Yasuda, Peter R. Leeds, De‐Maw Chuang · 2009 · Journal of Neurochemistry
  137. Inhibition of Wnt signaling, modulation of Tau phosphorylation and induction of neuronal cell death by DKK1
    Carla Scali, Filippo Caraci, Marco Gianfriddo, Enrica Diodato, Renza Roncarati, Giuseppe Pollio, Giovanni Gaviraghi, Agata Copani, Ferdinando Nicoletti, Georg C. Terstappen et al. · 2006 · Neurobiology of Disease
  138. Mesenchymal Stem Cells Primed With Valproate and Lithium Robustly Migrate to Infarcted Regions and Facilitate Recovery in a Stroke Model
    Li‐Kai Tsai, Zhifei Wang, Jeeva Munasinghe, Yan Leng, Peter R. Leeds, De‐Maw Chuang · 2011 · Stroke
  139. High resolution methylation analysis of the FMR1 gene trinucleotide repeat region in fragile X syndrome
    Lan K. Hornstra, David Lee Nelson, Stephen T. Warren, Thomas P. Yang · 1993 · Human Molecular Genetics
  140. β-Amyloid peptide-induced death of PC 12 cells and cerebellar granule cell neurons is inhibited by long-term lithium treatment
    Huafeng Wei, Peter R. Leeds, Yanning Qian · 2000 · European Journal of Pharmacology
  141. Abnormal SMN1 gene copy number is a susceptibility factor for amyotrophic lateral sclerosis
    Philippe Corcia, Véronique Mayeux‐Portas, Jawad Khoris, Bertrand de Toffol, Alain Autret, J.P. Müh, William Camu, Christian Robert Andres · 2002 · Annals of Neurology
  142. Prevention of MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) dopaminergic neurotoxicity in mice by chronic lithium: involvements of Bcl-2 and Bax
    Zaher Arraf, Moussa B. H. Youdim · 2004 · Neuropharmacology
  143. Mutant Huntingtin reduces HSP70 expression through the sequestration of NF‐Y transcription factor
    Tomoyuki Yamanaka, Haruko Miyazaki, Fumitaka Oyama, Masaru Kurosawa, Chika Washizu, Hiroshi Doi, Nobuyuki Nukina · 2008 · The EMBO Journal
  144. Regulation of Cortical Interneurons by Neurotrophins: From Development to Cognitive Disorders
    Newton H. Woo, Bai Lu · 2006 · The Neuroscientist
  145. BRAN AND BLOOD-LIPIDS
    I. Persson, KN. Raby, Peter Fønss-Bech, Eva N. Jensen · 1975 · The Lancet
  146. Randomized sequential trial of valproic acid in amyotrophic lateral sclerosis
    Sanne Piepers, Jan Herman Veldink, Sonja W. de Jong, Ingeborg van der Tweel, W. Ludo van der Pol, Esther V. Uijtendaal, Helenius Jurgen Schelhaas, Hans Scheffer, Marianne de Visser, J.M.B.V. de Jong et al. · 2009 · Annals of Neurology
  147. Lithium regulates hippocampal neurogenesis by ERK pathway and facilitates recovery of spatial learning and memory in rats after transient global cerebral ischemia
    Xuebo Yan, Hailong Hou, Lin-Min Wu, Ji Liu, Jiang‐Ning Zhou · 2007 · Neuropharmacology
  148. Effects of lithium on oxidative stress parameters in healthy subjects
    Rodrigo Machado‐Vieira · 2011 · Molecular Medicine Reports
  149. Homozygous deletion of the survival motor neuron 2 gene is a prognostic factor in sporadic ALS
    Jan Herman Veldink, Leonard H. van den Berg, Jan Maarten Cobben, Rein P. Stulp, J.M.B.V. de Jong, Oscar J.M. Vogels, Frank Baas, John H. J. Wokke, Hans Scheffer · 2001 · Neurology
  150. Neuropsychological effects of valproate in traumatic brain injury
    S.S. Dikmen, Joan Machamer, H. Richard Winn · 2000 · Neurology
  151. Chronic lithium treatment decreases tau lesions by promoting ubiquitination in a mouse model of tauopathies
    Hanae Nakashima, Takeshi Ishihara, S. Pilar Suguimoto, Osamu Yokota, Etsuko Oshima, Aki Kugo, Seishi Terada, Takashi Hamamura, John Q. Trojanowski, Virginia M.‐Y. Lee et al. · 2005 · Acta Neuropathologica
  152. Long-Term Treatment with Lithium Alleviates Memory Deficits and Reduces Amyloid-β Production in an Aged Alzheimer's Disease Transgenic Mouse Model
    Xin Zhang, Xin Heng, Ting Li, Lixi Li, Dehua Yang, Xiaojie Zhang, Yunlan Du, Rachelle Smith Doody, Weidong Le · 2011 · Journal of Alzheimer s Disease
  153. Neuroprotective effects of valproic acid following transient global ischemia in rats
    Aiguo Xuan, Dahong Long, Jianhua Li, Weidong Ji, Le-Peng Hong, Meng Zhang, Wenjuan Zhang · 2012 · Life Sciences
  154. Cytoprotection by lithium and valproate varies between cell types and cellular stresses
    Justin S. Lai, Chunnian Zhao, Jerry J. Warsh, Peter P. Li · 2006 · European Journal of Pharmacology
  155. Recent advances in fragile X: a model for autism and neurodegeneration
    Randi Jenssen Hagerman, Michele Y. Ono, Paul J. Hagerman · 2005 · Current Opinion in Psychiatry
  156. Regulation of tau phosphorylation and protection against β‐amyloid‐induced neurodegeneration by lithium. Possible implications for Alzheimer's disease
    Gema Alvarez, Juan Ramón Muñoz-Montaño, Jorgina Satrústegui, Jesús Ávila, Elena Bogónez, Javier Díaz‐Nido · 2002 · Bipolar Disorders
  157. Intracellular mechanisms underlying aluminum-induced apoptosis in rabbit brain
    J Savory · 2003 · Journal of Inorganic Biochemistry
  158. Chronic Valproate Treatment Enhances Postischemic Angiogenesis and Promotes Functional Recovery in a Rat Model of Ischemic Stroke
    Zhifei Wang, Li‐Kai Tsai, Jeeva Munasinghe, Yan Leng, Emily Bame Fessler, Fairouz L. Chibane, Peter R. Leeds, De‐Maw Chuang · 2012 · Stroke
  159. Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibition
    Kidd, Sarah K., Schneider, Jay S. · 2010 · Brain Research
  160. The regulation of phosphorylation of τ in SY5Y neuroblastoma cells: the role of protein phosphatases
    Toshihisa Tanaka, Jun Zhong, Khalid Iqbal, Ekkhart Trenkner, Inge Grundke · 1998 · FEBS Letters
  161. Short-term lithium treatment promotes neuronal survival and proliferation in rat striatum infused with quinolinic acid, an excitotoxic model of Huntington's disease
    Vladimir V. Senatorov, M Ren, Hirohiko Kanai, Huafeng Wei, D M Chuang · 2003 · Molecular Psychiatry
  162. Valproic acid increases white matter repair and neurogenesis after stroke
    Xuesheng Liu, Michael Chopp, Haifa Kassis, Longfei Jia, Ann Hozeska‐Solgot, R.L. Zhang, C. Chen, Y.S. Cui, Zhixian Zhang · 2012 · Neuroscience
  163. Vascular endothelial growth factor protects spinal cord motoneurons against glutamate‐induced excitotoxicity via phosphatidylinositol 3‐kinase
    Laia Tolosa, Margalida Mir, Víctor J. Asensio, Gabriel Olmos, Jerònia Lladó · 2007 · Journal of Neurochemistry
  164. Lithium Regulates Glycogen Synthase Kinase-3β in Human Peripheral Blood Mononuclear Cells: Implication in the Treatment of Bipolar Disorder
    Xiaohua Li, Ari B. Friedman, Wawa Zhu, Li Wang, Sherer Boswell, Roberta May, Lori L. Davis, Richard Scott Jope · 2006 · Biological Psychiatry
  165. Antiepileptic drug use in women of childbearing age
    Kimford J. Meador, Patricia E. Penovich, Gus A. Baker et al. · 2009 · Epilepsy & Behavior
  166. Adult human hematopoietic stem cells produce neurons efficiently in the regenerating chicken embryo spinal cord
    Ólafur E. Sigurjónsson, Marie‐Claude Perreault, TORSTEIN EGELAND, Joel Clinton Glover · 2005 · Proceedings of the National Academy of Sciences
  167. Lithium Reduces BACE1 Overexpression, Beta Amyloid Accumulation, and Spatial Learning Deficits in Mice with Traumatic Brain Injury
    Fengshan Yu, Yumin Zhang, De‐Maw Chuang · 2012 · Journal of Neurotrauma
  168. INCOMPRESSIBLE VESSELS
    Leslie Klenerman, J D Lewis · 1976 · The Lancet
  169. SMN genotypes producing less SMN protein increase susceptibility to and severity of sporadic ALS
    Jan Herman Veldink, Sandra Kalmijn, Annemarie H. van der Hout, Henny H. Lemmink, Geert Jan Groeneveld, Chantal Lummen, Hans Scheffer, John H. J. Wokke, Leonard H. van den Berg · 2005 · Neurology
  170. Lithium-Mediated Long-Term Neuroprotection in Neonatal Rat Hypoxia–Ischemia is Associated with Antiinflammatory Effects and Enhanced Proliferation and Survival of Neural Stem/Progenitor Cells
    Hongfu Li, Qian Li, Xiaonan Du, Yanyan Sun, Xiaoyang Wang, Guido Kroemer, Klas Blomgren, Changlian Zhu · 2011 · Journal of Cerebral Blood Flow & Metabolism
  171. Proteasomal dysfunction in aging and Huntington disease
    Xiao‐Jiang Li, Shihua Li · 2010 · Neurobiology of Disease
  172. Anxiety and physical illness in the elderly.
    J M Turnbull · 1989 · PubMed
  173. Lithium Chloride Reinforces the Regeneration-Promoting Effect of Chondroitinase ABC on Rubrospinal Neurons after Spinal Cord Injury
    Yick, Leung-Wah, So, Kwok-Fai, Cheung, Pik-To, Wu, Wu-Tian · 2004 · Journal of Neurotrauma
  174. Functional Repression of cAMP Response Element in 6-Hydroxydopamine-treated Neuronal Cells*
    E. M. Chalovich, Jian-Hui Zhu, John Caltagarone, R. Bowser, Charleen T. Chu · 2006 · Journal of Biological Chemistry
  175. Proton magnetic resonance spectroscopy in Huntington's disease: Evidence in favour of the glutamate excitotoxic theory?
    Simon David Taylor-Robinson, RobertA. Weeks, D. J. Bryant, Janet Sargentoni, ClaudeD. Marcus, A. E. Harding, David James Brooks · 1996 · Movement Disorders
  176. Newer anticonvulsants in the treatment of bipolar disorder.
    Lakshmi N. Yatham · 2004 · PubMed
  177. Valproate inhibits oxidative damage to lipid and protein in primary cultured rat cerebrocortical cells
    Junfeng Wang, Joseph E. Azzam, Lionel Trevor Young · 2003 · Neuroscience
  178. A Placebo-Controlled Trial of Valproate for Agitation and Aggression in Alzheimer’s Disease
    Nathan Herrmann, Krista L. Lanctôt, Lana S. Rothenburg, Goran M. Eryavec · 2006 · Dementia and Geriatric Cognitive Disorders
  179. Role of glycogen synthase kinase-3β in early depressive behavior induced by mild traumatic brain injury
    Moran Shapira, Avital Licht-Murava, Anat Milman, Chaim G. Pick, Esther Shohami, Hagit Eldar-Finkelman · 2006 · Molecular and Cellular Neuroscience
  180. Disorders of reproduction in patients with epilepsy: Antiepileptic drug related mechanisms
    Jouko I. T. Isojärvi · 2008 · Seizure
  181. Lithium Ameliorates HIV-gp120-Mediated Neurotoxicity
    Ian Everall · 2002 · Molecular and Cellular Neuroscience
  182. Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology.
    Leroy, Karelle, Ando, Kunie, Héraud, Céline, Yilmaz, Zehra, Authelet, Michèle, Boeynaems, Jean-Marie, Buée, Luc, De Decker, Robert, Brion, Jean-Pierre · 2010 · Journal of Alzheimer's Disease
  183. Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2
    T Hiroi, Huafeng Wei, Christopher J. Hough, Peter R. Leeds, D M Chuang · 2005 · The Pharmacogenomics Journal
  184. Mode of Action: Inhibition of Histone Deacetylase, Altering WNT-Dependent Gene Expression, and Regulation of Beta-Catenin—Developmental Effects of Valproic Acid
    Jeanette A. Wiltse · 2005 · Critical Reviews in Toxicology
  185. Lithium stimulates progenitor proliferation in cultured brain neurons
    Ryota Hashimoto, Vladimir V. Senatorov, Hirohiko Kanai, Peter R. Leeds, D M Chuang · 2003 · Neuroscience
  186. A double‐blind, parallel, multicenter comparison of <scp>L</scp>‐acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boys
    Torrioli, M. Giulia, Vernacotola, Silvia, Peruzzi, Laura, Tabolacci, Elisabetta, Mila, Montserrat, Militerni, Roberto, Musumeci, Sebastiano, Ramos, Feliciano J., Frontera, Marìa, Sorge, Giovanni et al. · 2008 · American Journal of Medical Genetics Part A
  187. Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3β transgenes
    Janet Brownlees, Nicholas G. Irving, Jean‐Pierre Brion, Barry J. M. Gibb, Uta Wagner, James Robert Woodgett, Christopher C.J. Miller · 1997 · Neuroreport
  188. Lithium enhances proliferation and neuronal differentiation of neural progenitor cells in vitro and after transplantation into the adult rat spinal cord
    Huanxing Su, Tak‐Ho Chu, Wutian Wu · 2007 · Experimental Neurology
  189. The Patents-Based Pharmaceutical Development Process
    John H. Barton, Ezekiel J. Emanuel · 2005 · JAMA
  190. Lithium and dementia: A preliminary study
    Takeshi Terao, Hideki Nakano, Yoshiaki Inoue, Tatsuya Okamoto, Jun Nakamura, Noboru Iwata · 2006 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  191. Lithium and hematology: established and proposed uses
    Focosi, Daniele, Azzarà, Antonio, Kast, Richard Eric, Carulli, Giovanni, Petrini, Mario · 2009 · Journal of Leukocyte Biology
  192. Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury
    Na’ama A. Shein, Nikolaos Grigoriadis, Alexander G. Alexandrovich, Constantina Simeonidou, Athanasios I. Lourbopoulos, Eleni Polyzoidou, Victoria Trembovler, Paolo Mascagni, Charles Anthony Dinarello, Esther Shohami · 2009 · The FASEB Journal
  193. Potential autophagy enhancers attenuate rotenone-induced toxicity in SH-SY5Y
    Nian Xiong, Min Jia, Chung‐Kuan Chen, Jing Xiong, Z. Zhang, J. Huang, L. Hou, Hecheng Yang, Xin Cao, Zhihou Liang et al. · 2011 · Neuroscience
  194. Expression of Vascular Endothelial Growth Factor and Its Receptors in the Central Nervous System in Amyotrophic Lateral Sclerosis
    Alice Brockington, Stephen B. Wharton, Malee S Fernando, Catherine Gelsthorpe, Lynne Baxter, Paul G. Ince, Claire E. Lewis, Pamela J. Shaw · 2006 · Journal of Neuropathology & Experimental Neurology
  195. Support of Retinal Ganglion Cell Survival and Axon Regeneration by Lithium through a Bcl-2-Dependent Mechanism
    Xizhong Huang, Da-Yu Wu, Guang Chen, Husseini K. Manji, Dong Feng Chen · 2003 · Investigative Ophthalmology & Visual Science
  196. Lithium carbonate in amyotrophic lateral sclerosis: Lack of efficacy in a dose-finding trial
    Chiò, A., Borghero, G., Calvo, A., Capasso, M., Caponnetto, C., Corbo, M., Giannini, F., Logroscino, G., Mandrioli, J., Marcello, N. et al. · 2010 · Neurology
  197. Role of ubiquitin–proteasome-mediated proteolysis in nervous system disease
    Ashok N. Hegde, Sudarshan C. Upadhya · 2010 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  198. Differential Display PCR Reveals Novel Targets for the Mood-Stabilizing Drug Valproate Including the Molecular Chaperone GRP78
    Junfeng Wang, Christopher D. Bown, L. Trevor Young · 1999 · Molecular Pharmacology
  199. Valproate protects the retina from endoplasmic reticulum stress-induced apoptosis after ischemia–reperfusion injury
    Zhenzhen Zhang, Nianting Tong, Yuanyuan Gong, Qinghua Qiu, Lili Yin, Xiu-Hong Lv, Xingwei Wu · 2011 · Neuroscience Letters
  200. Association of the putative susceptibility gene, transient receptor potential protein melastatin type 2, with bipolar disorder
    Chun Di Xu, Fabio M. Macciardi, Peter P. Li, Il‐Sang Yoon, R.G. Cooke, Bronwen Hughes, Sagar V. Parikh, Roger S. McIntyre, James L. Kennedy, Jerry J. Warsh · 2005 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics