Therapeutic potential of mood stabilizers lithium and valproic acid:Beyond bipolar disorder
Cites (580)
Items 201–400 of 580
- Valproic acid increases SMN levels in spinal muscular atrophy patient cellsCharlotte J. Sumner, Thanh N. Huynh, Jennifer A. Markowitz, J. Stephen Perhac, Brenna J. Hill, Daniel D. Coovert, Kristie R. Schussler, Xiaocun Chen, Jill Jarecki, Arthur H.M. Burghes et al. · 2003 · Annals of Neurology
- Neuroprotective Effects of Regulators of the Glycogen Synthase Kinase-3β Signaling Pathway in a Transgenic Model of Alzheimer's Disease Are Associated with Reduced Amyloid Precursor Protein PhosphorylationEdward M. Rockenstein, Magdalena Torrance, Anthony Adame, Michael Mante, Pazit Bar‐On, John Bart Rose, Leslie A. Crews, Eliezer Masliah · 2007 · Journal of Neuroscience
- Mental Health Service Utilization by Borderline Personality Disorder Patients and Axis II Comparison Subjects Followed Prospectively for 6 YearsZanarini, Mary C., Frankenburg, Frances R., Hennen, John, Silk, Kenneth R. · 2004 · The Journal of Clinical Psychiatry
- Cellular Plasticity Cascades: Targets for the Development of Novel Therapeutics for Bipolar DisorderCarlos A. Zarate, Jaskaran B. Singh, Husseini K. Manji · 2006 · Biological Psychiatry
- Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on β-catenin in mouse hippocampusOksana Kaidanovich‐Beilin, Anat Milman, Abraham Weizman, Chaim G. Pick, Hagit Eldar-Finkelman · 2004 · Biological Psychiatry
- α‐Synuclein contributes to GSK‐3β‐catalyzed Tau phosphorylation in Parkinson's disease modelsTetyana Duka, Valeriy Duka, Jeffrey N. Joyce, Anita Sidhu · 2009 · The FASEB Journal
- Understanding microRNAs in neurodegenerationStephen M. Eacker, Ted M. Dawson, Valina Lynn Dawson · 2009 · Nature reviews. Neuroscience
- Transcriptional signatures in Huntington's diseaseJang-Ho J. Cha · 2007 · Progress in Neurobiology
- Stem cell technology for neurodegenerative diseasesJ. Simon Lunn, Stacey A. Sakowski, Junguk Hur, Eva L. Feldman · 2011 · Annals of Neurology
- National US Estimates of Recombinant Tissue Plasminogen Activator UseDawn Kleindorfer, Christopher John Lindsell, Lawrence M. Brass, Walter J. Koroshetz, Joseph P. Broderick · 2008 · Stroke
- Lithium protects cultured neurons against β‐amyloid‐induced neurodegenerationGema Alvarez, Juan Ramón Muñoz-Montaño, Jorgina Satrústegui, Jesús Ávila, Elena Bogónez, Javier Díaz‐Nido · 1999 · FEBS Letters
- Lithium Treatment and Risk of DementiaKessing, Lars Vedel, Søndergård, Lars, Forman, Julie Lyng, Andersen, Per Kragh · 2008 · Archives of General Psychiatry
- Clusterin: A forgotten player in Alzheimer's diseaseNuutinen, Tapio, Suuronen, Tiina, Kauppinen, Anu, Salminen, Antero · 2009 · Brain Research Reviews
- SDF-1α/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat modelYe Wang, Yubin Deng, Guangqian Zhou · 2008 · Brain Research
- GSK-3β inhibition reverses axonal transport defects and behavioural phenotypes in DrosophilaMudher, A, Shepherd, D, Newman, T A, Mildren, P, Jukes, J P, Squire, A, Mears, A, Berg, S, MacKay, D, Asuni, A A et al. · 2004 · Molecular Psychiatry
- Increased gray matter volume in lithium-treated bipolar disorder patientsRoberto B. Sassi, Mark Nicoletti, Paolo Brambilla, Alan G. Mallinger, Ellen Frank, David J. Kupfer, Matcheri S. Keshavan, Jair C. Soares · 2002 · Neuroscience Letters
- The NeurotroDhins BDNF, NT‐3 and NT‐4/5 Promote Survival and Morphological and Biochemical Differentiation of Striatal Neurons In VitroRoseann Ventimiglia, Pamela E. Mather, Bruce Edward Jones, Ronald M. Lindsay · 1995 · European Journal of Neuroscience
- Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicityChen, P.S., Wang, C.-C., Bortner, C.D., Peng, G.-S., Wu, X., Pang, H., Lu, R.-B., Gean, P.-W., Chuang, D.-M., Hong, J.-S. · 2007 · Neuroscience
- Biochemical interactions in the wnt pathwayMartin J. Seidensticker, Jürgen Behrens · 2000 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: An essential step for neuroprotection against glutamate excitotoxicityRyota Hashimoto, Nobuyuki Takei, Kazuhiro Shimazu, Lori A. Christ, Bai Lu, De‐Maw Chuang · 2002 · Neuropharmacology
- Post-menopausal oestrogen therapy.Richard J. Lindsay · 1979 · PubMed
- Upregulation of Dicer and MicroRNA Expression in the Dorsolateral Prefrontal Cortex Brodmann Area 46 in SchizophreniaDanielle M. Santarelli, Natalie Jane Beveridge, Paul A. Tooney, Murray J. Cairns · 2010 · Biological Psychiatry
- Pharmacological Inhibition of Histone Deacetylases by Suberoylanilide Hydroxamic Acid Specifically Alters Gene Expression and Reduces Ischemic Injury in the Mouse BrainGiuseppe Faraco, Tristano Pancani, Laura Formentini, Paolo Mascagni, Gianluca Fossati, Flavio Leoni, Flavio Moroni, Alberto Chiarugi · 2006 · Molecular Pharmacology
- Neuroprotective effects of chronic lithium on focal cerebral ischemia in ratsShigeyuki Nonaka, De‐Maw Chuang · 1998 · Neuroreport
- Altered MicroRNA Expression Profiles in Postmortem Brain Samples from Individuals with Schizophrenia and Bipolar DisorderMoreau, Michael P., Bruse, Shannon E., David-Rus, Richard, Buyske, Steven, Brzustowicz, Linda M. · 2011 · Biological Psychiatry
- Lithium-Induced Gray Matter Volume Increase As a Neural Correlate of Treatment Response in Bipolar Disorder: A Longitudinal Brain Imaging StudyIn Kyoon Lyoo, Stephen R. Dager, Jieun E. Kim, Sujung J. Yoon, Seth D. Friedman, David L. Dünner, Perry Franklin Renshaw · 2010 · Neuropsychopharmacology
- Acceleration and Augmentation of Antidepressants With Lithium for Depressive Disorders: Two Meta-Analyses of Randomized, Placebo-Controlled TrialsCrossley, Nicolas Andres, Bauer, Michael · 2007 · The Journal of Clinical Psychiatry
- Specification of the Neurobehavioral Phenotype in Males with Fragile X SyndromeThomas L. Baumgardner, Allan L. Reiss, Lisa S. Freund, Michael T. Abrams · 1995 · PEDIATRICS
- Widespread Disruption of Repressor Element-1 Silencing Transcription Factor/Neuron-Restrictive Silencer Factor Occupancy at Its Target Genes in Huntington's DiseaseZuccato, C., Belyaev, N., Conforti, P., Ooi, L., Tartari, M., Papadimou, E., MacDonald, M., Fossale, E., Zeitlin, S., Buckley, N. et al. · 2007 · Journal of Neuroscience
- Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer diseaseRicobaraza, Ana, Cuadrado‐Tejedor, Mar, Marco, Sonia, Pérez‐Otaño, Isabel, García‐Osta, Ana · 2012 · Hippocampus
- Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizersTodd D. Gould, Jorge A. Quiroz, Jaskaran B. Singh, Carlos A. Zarate, H.K. Manji · 2004 · Molecular Psychiatry
- A Longitudinal Study of the Effects of Lithium Treatment on Prefrontal and Subgenual Prefrontal Gray Matter Volume in Treatment-Responsive Bipolar Disorder PatientsMoore, Gregory J., Cortese, Bernadette M., Glitz, Debra A., Zajac-Benitez, Caroline, Quiroz, Jorge A., Uhde, Thomas W., Drevets, Wayne C., Manji, Husseini K. · 2009 · The Journal of Clinical Psychiatry
- Inactivation of Glycogen Synthase Kinase 3 Promotes Axonal Growth and Recovery in the CNSJohn Dill, Hongyu Wang, Feng‐Quan Zhou, Shuxin Li · 2008 · Journal of Neuroscience
- Valproic Acid Attenuates Blood–Brain Barrier Disruption in a Rat Model of Transient Focal Cerebral Ischemia: The Roles of HDAC and MMP-9 InhibitionZhifei Wang, Yan Leng, Li‐Kai Tsai, Peter R. Leeds, De‐Maw Chuang · 2010 · Journal of Cerebral Blood Flow & Metabolism
- Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse modelHonglin Feng, Yan Leng, Cong Ma, Jinzhi Zhang, Ming Ren, D M Chuang · 2008 · Neuroscience
- Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disordersChi‐Tso Chiu, De‐Maw Chuang · 2010 · Pharmacology & Therapeutics
- Untitled work2011 · 10.2165/11586970-000000000-00000
- Novel Insights into Lithium’s Mechanism of Action: Neurotrophic and Neuroprotective EffectsJorge A. Quiroz, Rodrigo Machado‐Vieira, Carlos A. Zarate, Husseini K. Manji · 2010 · Neuropsychobiology
- Anti-Inflammatory Effects of the 70 kDa Heat Shock Protein in Experimental StrokeZhen Zheng, Jong Youl Kim, Hualong Ma, Jong Eun Lee, Midori Anne Yenari · 2007 · Journal of Cerebral Blood Flow & Metabolism
- Chronic Divalproex Sodium to Attenuate Agitation and Clinical Progression of Alzheimer DiseasePierre N. Tariot · 2011 · Archives of General Psychiatry
- Lithium levels in drinking water and risk of suicideHirochika Ohgami, Takeshi Terao, Ippei Shiotsuki, Nobuyoshi Ishii, Noboru Iwata · 2009 · The British Journal of Psychiatry
- In Vivo Evidence in the Brain for Lithium Inhibition of Glycogen Synthase Kinase-3Todd D. Gould, Guang Jing Chen, Husseini K. Manji · 2003 · Neuropsychopharmacology
- Phosphorylation of paired helical filament tau in Alzheimer's disease neurofibrillary lesions: focusing on phosphatases.John Q. Trojanowski, V M Lee · 1995 · The FASEB Journal
- Multiphasic roles for matrix metalloproteinases after strokeROSELL, A, LO, E · 2008 · Current Opinion in Pharmacology
- Synergistic Neuroprotective Effects of Lithium and Valproic Acid or Other Histone Deacetylase Inhibitors in Neurons: Roles of Glycogen Synthase Kinase-3 InhibitionYan Leng, Min‐Huei Liang, Ming Ren, Zoya Marinova, Peter R. Leeds, De‐Maw Chuang · 2008 · Journal of Neuroscience
- Motor Deficit in a Drosophila Model of Mucolipidosis Type IV due to Defective Clearance of Apoptotic CellsKartik Venkatachalam, Ashleigh Long, Rebecca S. Elsaesser, Daria Nikolaeva, Kendal S. Broadie, Craig Montell · 2008 · Cell
- Open-Label Treatment Trial of Lithium to Target the Underlying Defect in Fragile X SyndromeBerry-Kravis, Elizabeth, Sumis, Allison, Hervey, Crystal, Nelson, Michael, Porges, Stephen W., Weng, Ning, Weiler, Ivan Jeanne, Greenough, William T. · 2008 · Journal of Developmental & Behavioral Pediatrics
- Sodium Valproate Exerts Neuroprotective EffectsIn Vivothrough CREB-Binding Protein-Dependent Mechanisms But Does Not Improve Survival in an Amyotrophic Lateral Sclerosis Mouse ModelCaroline Rouaux, Irina Panteleeva, Frédérique René, José‐Luis González de Aguilar, Andoni Echaniz‐Laguna, Luc Dupuis, Yannick Menger, Anne‐Laurence Boutillier, Jean‐Philippe Loeffler · 2007 · Journal of Neuroscience
- Bilateral hippocampal volume increases after long-term lithium treatment in patients with bipolar disorder: a longitudinal MRI studyKaan Yücel, Margaret C. McKinnon, Valerie H. Taylor, Kathryn Macdonald, Martin Alda, Lionel Trevor Young, GLENDA M. MacQUEEN · 2007 · Psychopharmacology
- Benefit of valproic acid in suppressing disease progression of ALS model miceFuminobu Sugai, Yoichi Yamamoto, Katsuyuki Miyaguchi, Zhiwei Zhou, Hisae Sumi, Toshimitsu Hamasaki, Masashi Goto, Saburo Sakoda · 2004 · European Journal of Neuroscience
- Bilateral Hippocampal Volume Increase in Patients with Bipolar Disorder and Short-term Lithium TreatmentKaan Yücel, Valerie H. Taylor, Margaret C. McKinnon, Kathryn Macdonald, Martin Alda, Lionel Trevor Young, GLENDA M. MacQUEEN · 2007 · Neuropsychopharmacology
- Identification of New Genetic Risk Variants for Type 2 DiabetesXiao Ou Shu, Jirong Long, Qiuyin Cai, Lu Qi, Yong‐Bing Xiang, Yoon Shin Cho, E Shyong Tai, Xiangyang Li, Lin Xu, Wong‐Ho Chow et al. · 2010 · PLoS Genetics
- Inflammation Induced by Infection Potentiates Tau Pathological Features in Transgenic MiceSy, Michael, Kitazawa, Masashi, Medeiros, Rodrigo, Whitman, Lucia, Cheng, David, Lane, Thomas E., LaFerla, Frank M. · 2011 · The American Journal of Pathology
- GSK3 Influences Social Preference and Anxiety-Related Behaviors during Social Interaction in a Mouse Model of Fragile X Syndrome and AutismMarjelo A. Mines, Christopher J. Yuskaitis, Margaret K. King, Eléonore Beurel, Richard Scott Jope · 2010 · PLoS ONE
- Alteration in Kinase Activity But Not in Protein Levels of Protein Kinase B and Glycogen Synthase Kinase-3β in Ventral Prefrontal Cortex of Depressed Suicide VictimsFélicien Karege, Nader Ali Perroud, Sandra Burkhardt, Michèle Schwald, Eladia Ballmann, Romano La Harpe, Alain Malafosse · 2006 · Biological Psychiatry
- GDNF and GFRα: a versatile molecular complex for developing neuronsGustavo Paratcha, Fernanda Ledda · 2008 · Trends in Neurosciences
- MOLECULAR EFFECTS of lithiumJ. A. Quiroz · 2004 · Molecular Interventions
- Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion modelMing Ren, Vladimir V. Senatorov, Ren‐Wu Chen, De‐Maw Chuang · 2003 · Proceedings of the National Academy of Sciences
- 3-Nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorderAna C. Andreazza, Flávio Pereira Kapczinski, Marcia Kauer‐Sant’Anna, Júlio Cesar Walz, David J. Bond, Carlos Alberto Gonçalves, Lionel Trevor Young, Lakshmi N. Yatham · 2009 · Journal of Psychiatry and Neuroscience
- Apoptosis in Huntington's diseaseMiriam Ann Hickey, Marie-Françoise Chesselet · 2003 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Mutant Huntingtin Enhances Excitotoxic Cell DeathMelinda M. Zeron, Nansheng Chen, Ali Moshaver, Allen Ting Chun Lee, Cheryl Lea Wellington, Michael R. Hayden, Lynn A. Raymond · 2001 · Molecular and Cellular Neuroscience
- Inhibition of Protein Phosphatase 2A Overrides Tau Protein Kinase I/Glycogen Synthase Kinase 3β and Cyclin-dependent Kinase 5 Inhibition and Results in Tau Hyperphosphorylation in the Hippocampus of Starved MouseEmmanuel Planel, Kaori Yasutake, Shinobu C. Fujita, Koichi Ishiguro · 2001 · Journal of Biological Chemistry
- Active HSF1 Significantly Suppresses Polyglutamine Aggregate Formation in Cellular and Mouse ModelsMitsuaki Fujimoto, Eiichi Takaki, Tetsuya Hayashi, Yasushi Kitaura, Yasunori Tanaka, Sachiye Inouye, Akira Nakai · 2005 · Journal of Biological Chemistry
- Lithium neuroprotection: molecular mechanisms and clinical implicationsMichael K. Rowe, De‐Maw Chuang · 2004 · Expert Reviews in Molecular Medicine
- Safety and efficacy of lithium in combination with riluzole for treatment of amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trialAggarwal, Swati P, Zinman, Lorne, Simpson, Elizabeth, McKinley, Jane, Jackson, Katherine E, Pinto, Hanika, Kaufman, Petra, Conwit, Robin A, Schoenfeld, David, Shefner, Jeremy et al. · 2010 · The Lancet Neurology
- Glycogen Synthase Kinase-3β Inhibitors Prevent Cellular Polyglutamine Toxicity Caused by the Huntington’s Disease MutationJenny Carmichael, Katherine L. Sugars, Yi Ping Bao, David Chaim Rubinsztein · 2002 · Journal of Biological Chemistry
- Reduced left anterior cingulate volumes in untreated bipolar patientsRoberto B. Sassi, Paolo Brambilla, John P. Hatch, Mark Nicoletti, Alan G. Mallinger, Ellen Frank, David J. Kupfer, Matcheri S. Keshavan, Jair C. Soares · 2004 · Biological Psychiatry
- On the excitotoxic properties of quinolinic acid, 2,3-piperidine dicarboxylic acids and structurally related compoundsAlan C. Foster · 1983 · Neuropharmacology
- Valproate Administered after Traumatic Brain Injury Provides Neuroprotection and Improves Cognitive Function in RatsPramod K. Dash, Sara A. Orsi, Min Zhang, Raymond J. Grill, Shibani Pati, Jing Zhao, Anthony N. Moore · 2010 · PLoS ONE
- Lithium regulates adult hippocampal progenitor development through canonical Wnt pathway activationEric Wexler, Daniel H. Geschwind, Theo D. Palmer · 2007 · Molecular Psychiatry
- Behavioural abnormalities contribute to functional decline in Huntington's diseaseJoanne M. Hamilton · 2002 · Journal of Neurology Neurosurgery & Psychiatry
- MicroRNA-134 plasma levels before and after treatment for bipolar maniaHan Rong, Tie Bang Liu, Kong Jun Yang, Hai Chen Yang, Dong Wu, Chun-ping Liao, Fei Hong, He Zen Yang, Feng Wan, Xiao Ying Ye et al. · 2010 · Journal of Psychiatric Research
- The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger systemLuca Maria Neri, Paola Borgatti, Silvano Capitani, Alberto Maria Martelli · 2002 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Lithium induces clearance of protease resistant prion protein in prion‐infected cells by induction of autophagyAndreas Heiseke, Yasmine Aguib, Constanze Riemer, Michael Baier, Hermann M. Schätzl · 2009 · Journal of Neurochemistry
- Oxidative stress parameters in plasma of Huntington's disease patients, asymptomatic Huntington’s disease gene carriers and healthy subjectsN. Klepac, Maja Relja, R. Klepac, Silva Katusic Hecimovic, Tomislav Babić, Vladimir Trkulja · 2007 · Journal of Neurology
- Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse modelMar Pérez, Félix Hernández, Filip Lim, Javier Díaz‐Nido, Jesús Ávila · 2003 · Journal of Alzheimer s Disease
- Glucose Regulated Protein 78 Diminishes α-Synuclein Neurotoxicity in a Rat Model of Parkinson DiseaseMarina S. Gorbatyuk, Arseniy E. Shabashvili, Weijun Chen, Craig Meyers, Layla F Sullivan, Max Salganik, Jonathan H. Lin, Alfred S. Lewin, Nicholas Muzyczka, Oleg S. Gorbatyuk · 2012 · Molecular Therapy
- AAV-Mediated gene delivery of BDNF or GDNF is neuroprotective in a model of huntington diseaseAdrian P. Kells, Dahna M. Fong, Mike Dragunow, Matthew J. During, Deborah Young, Bronwen J. Connor · 2004 · Molecular Therapy
- Lithium Increases Transcription Factor Binding to AP‐1 and Cyclic AMP‐Responsive Element in Cultured Neurons and Rat BrainNaoko Ozaki, De‐Maw Chuang · 1997 · Journal of Neurochemistry
- Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3β and attenuated by lithiumTaj D. King, Gautam N. Bijur, Richard Scott Jope · 2001 · Brain Research
- Abnormalities in brain structure and behavior in GSK-3alpha mutant miceOksana Kaidanovich‐Beilin, Tatiana V. Lipina, Keizo Takao, Matthijs van Eede, Satoko Hattori, Christine L. Laliberté, Mustafa Khan, Kenichi Okamoto, John W Chambers, Paul J. Fletcher et al. · 2009 · Molecular Brain
- Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activationDong-In Sinn, Se-Jeong Kim, Kon Chu, Keun‐Hwa Jung, Soon‐Tae Lee, Eun‐Cheol Song, Jeong‐Min Kim, Dong-Kyu Park, Sang Kun Lee, Manho Kim et al. · 2007 · Neurobiology of Disease
- Inhibition of GSK-3 Ameliorates Aβ Pathology in an Adult-Onset Drosophila Model of Alzheimer's DiseaseSofola, Oyinkan, Kerr, Fiona, Rogers, Iain, Killick, Richard, Augustin, Hrvoje, Gandy, Carina, Allen, Marcus J., Hardy, John, Lovestone, Simon, Partridge, Linda · 2010 · PLoS Genetics
- Lithium: Bipolar disorder and neurodegenerative diseases Possible cellular mechanisms of the therapeutic effects of lithiumFrederic Mármol · 2008 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Glycogen Synthase Kinase-3 in the Etiology and Treatment of Mood DisordersRichard Scott Jope · 2011 · Frontiers in Molecular Neuroscience
- Valproic Acid is Neuroprotective in the Rotenone Rat Model of Parkinson’s Disease: Involvement of α-SynucleinBarbara Monti, Valentina Gatta, Francesca Piretti, Simonetta S. Raffaelli, Marco Virgili, Antonio Contestabile · 2009 · Neurotoxicity Research
- Inositol and IP3 Levels Regulate Autophagy—Biology and Therapeutic SpeculationsSovan Sarkar, David Chaim Rubinsztein · 2005 · Autophagy
- GSK-3 as a Target for Lithium-Induced Neuroprotection Against Excitotoxicity in Neuronal Cultures and Animal Models of Ischemic StrokeDe‐Maw Chuang, Zhifei Wang, Chi‐Tso Chiu · 2011 · Frontiers in Molecular Neuroscience
- Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microgliaGiia-Sheun Peng, Guorong Li, Nian‐Sheng Tzeng, Po-See Chen, De‐Maw Chuang, Yaw‐Don Hsu, Sufen Yang, Jau‐Shyong Hong · 2004 · Molecular Brain Research
- The mood stabilizer valproic acid stimulates GABA neurogenesis from rat forebrain stem cellsPascal Laeng, Richard L. Pitts, Andrew L. Lemire, Christopher E. Drabik, Arin Weiner, Haiping Tang, Rathi Thyagarajan, Barbara S. Mallon, C. Anthony Altar · 2004 · Journal of Neurochemistry
- Intracerebral Peripheral Blood Stem Cell (CD34+) Implantation Induces Neuroplasticity by Enhancing β1 Integrin-Mediated Angiogenesis in Chronic Stroke RatsWoei‐Cherng Shyu, Shinn‐Zong Lin, Ming‐Fu Chiang, Ching-Yuan Su, Hung Li · 2006 · Journal of Neuroscience
- Vascular Endothelial Growth Factor Overexpression Delays Neurodegeneration and Prolongs Survival in Amyotrophic Lateral Sclerosis MiceYaoming Wang, Xiao Ou Mao, Lin Xie, Surita Banwait, Hugo H. Marti, David A. Greenberg, Kunlin Jin · 2007 · Journal of Neuroscience
- Chronic Treatment With a Low Dose of Lithium Protects the Brain Against Ischemic Injury by Reducing Apoptotic DeathJihong Xu, Juraj Čulman, Annegret Blume, Stephan Brecht, Peter Gohlke · 2003 · Stroke
- Social Cognition Impairments in Relation to General Cognitive Deficits, Injury Severity, and Prefrontal Lesions in Traumatic Brain Injury PatientsJacoba Margje Spikman, Marieke E. Timmerman, Maarten V. Milders, Wencke S. Veenstra, Joukje van der Naalt · 2011 · Journal of Neurotrauma
- Fetal valproate syndrome.Jill Clayton‐Smith, Dian Donnai · 1995 · Journal of Medical Genetics
- HIV‐1 Tat‐Mediated Activation of Glycogen Synthase Kinase‐3β Contributes to Tat‐Mediated NeurotoxicitySanjay B. Maggirwar, Ning Tong, Servio H. Ramirez, Harris A. Gelbard, Stephen Dewhurst · 1999 · Journal of Neurochemistry
- Brain-Derived Neurotrophic Factor-Mediated Protection of Striatal Neurons in an Excitotoxic Rat Model of Huntington's Disease, as Demonstrated by Adenoviral Gene TransferAlexis‐Pierre Bemelmans, Philippe Horellou, Laurent Pradier, Isabelle Brunet, Philippe Colin, Jacques J. Mallet · 1999 · Human Gene Therapy
- microRNAs in neurons: manifold regulatory roles at the synapseGabriele Siegel, Reuben Saba, Gerhard M. Schratt · 2011 · Current Opinion in Genetics & Development
- Lithium Therapy Improves Neurological Function and Hippocampal Dendritic Arborization in a Spinocerebellar Ataxia Type 1 Mouse ModelKei Watase, Jennifer R. Gatchel, Yaling Sun, Effat S. Emamian, Richard Atkinson, Ronald Richman, Hidehiro Mizusawa, Harry T. Orr, Chad A. Shaw, Huda Yahya Zoghbi · 2007 · PLoS Medicine
- Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100Xiaoyan Sun, Shinji Sato, Ohoshi Murayama, M. Murayama, J.-M. Park, H. Yamaguchi, Akihiko Takashima · 2002 · Neuroscience Letters
- Three-Dimensional Mapping of Hippocampal Anatomy in Unmedicated and Lithium-Treated Patients with Bipolar DisorderCarrie E. Bearden, Paul M. Thompson, Rebecca A. Dutton, Benicio Noronha Frey, Marco Aurélio Monteiro Peluso, Mark Nicoletti, Nicole A. Dierschke, Kiralee M. Hayashi, Andrea D. Klunder, David C. Glahn et al. · 2007 · Neuropsychopharmacology
- Lithium ameliorates phenotypic deficits in a mouse model of fragile X syndromeZhonghua Liu, De‐Maw Chuang, Carolyn Beebe Smith · 2010 · The International Journal of Neuropsychopharmacology
- A feasibility and tolerability study of lithium in Alzheimer's diseaseAlastair Macdonald, Kate Briggs, Michaela Poppe, Andrea R. Higgins, Latha Velayudhan, Simon Lovestone · 2008 · International Journal of Geriatric Psychiatry
- Increase of BDNF Serum Concentration in Lithium Treated Patients with Early Alzheimer's DiseaseThomas Leyhe, Gerhard Wilhelm Eschweiler, Elke Stransky, Thomas Gasser, Peter Annas, Hans Basun, Christoph Laske · 2009 · Journal of Alzheimer s Disease
- Valproic acid promotes neuronal differentiation by induction of proneural factors in association with H4 acetylationIn Tag Yu, Jin-Yong Park, Sung Hyun Kim, Jeong-Sik Lee, Yong-Seok Kim, Hyeon Son · 2008 · Neuropharmacology
- Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor in a rat model of depressionAngelucci, Francesco, Aloe, Luigi, Jiménez-Vasquez, Patricia, Mathé, Aleksander A. · 2003 · The International Journal of Neuropsychopharmacology
- Wnt Signaling Regulates the Invasion Capacity of Human Mesenchymal Stem CellsPeter Neth, Marisa Karow, Virginia Egea, Juergen Hoelters, Marianne Jochum, Christian Ries · 2006 · Stem Cells
- Valproic Acid, a Molecular Lead to Multiple Regulatory PathwaysMarta Kostrouchová, Z Kostrouch, Marta Kostrouchová · 2007 · Folia Biologica
- Transcription, translation and fragile X syndromeKathryn B. Garber, Karen T. Smith, Daniel Reines, Stephen T. Warren · 2006 · Current Opinion in Genetics & Development
- Elevated glycogen synthase kinase-3 activity in Fragile X mice: Key metabolic regulator with evidence for treatment potentialMin, Wenzhong William, Yuskaitis, Christopher J., Yan, Qijiang, Sikorski, Christopher, Chen, Shengqiang, Jope, Richard S., Bauchwitz, Robert P. · 2009 · Neuropharmacology
- Lithium increases plasma brain-derived neurotrophic factor in acute bipolar mania: A preliminary 4-week studyRAFAEL TEIXEIRA DE SOUSA, Martinus Theodorus van de Bilt, Breno Satler Diniz, Rodolfo Braga Ladeira, Luis Valmor Portela, Diogo Onofre Souza, Orestes Vicente Forlenza, Wagner F. Gattaz, Rodrigo Machado‐Vieira · 2011 · Neuroscience Letters
- Predictors of nursing home placement in Huntington diseaseVictoria Wheelock, Teresa Tempkin, Karen S. Marder, MARTHA A. NANCE, Richard H. Myers, H. Zhao, Elise Kayson, Constance Orme, Ira Shoulson, the Huntington Study Group · 2003 · Neurology
- Histone deactylase inhibition combined with behavioral therapy enhances learning and memory following traumatic brain injuryPramod K. Dash, Sara A. Orsi, Amanda Moore · 2009 · Neuroscience
- Opposing Actions of Phosphatidylinositol 3‐Kinase and Glycogen Synthase Kinase‐3β in the Regulation of HSF‐1 ActivityGautam N. Bijur, Richard Scott Jope · 2000 · Journal of Neurochemistry
- Lithium Prevents and Ameliorates Experimental Autoimmune EncephalomyelitisPatrizia De Sarno, Robert C. Axtell, Chander Raman, Kevin Aaron Roth, Dario R. Alessi, Richard Scott Jope · 2008 · The Journal of Immunology
- Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: Impact of past episodesHALUK ASUMAN SAVAS, Hasan Serdar Gergerlioğlu, Ferah Armutçu, Hasan Herken, H. Ramazan Yılmaz, Esra Koçoğlu, Salih Selek, Hamdi Tutkun, Süleyman Salih Zoroğlu, Ömer Akyol · 2006 · The World Journal of Biological Psychiatry
- GSK-3 is a viable potential target for therapeutic intervention in bipolar disorderMichael K. Rowe, Charlotte Wiest, De‐Maw Chuang · 2007 · Neuroscience & Biobehavioral Reviews
- Ebola virus: new insights into disease aetiopathology and possible therapeutic interventionsThomas W. Geisbert, Lisa E. Hensley · 2004 · Expert Reviews in Molecular Medicine
- Combined Treatment with the Mood Stabilizers Lithium and Valproate Produces Multiple Beneficial Effects in Transgenic Mouse Models of Huntington's DiseaseChi‐Tso Chiu, Guangping Liu, Peter R. Leeds, De‐Maw Chuang · 2011 · Neuropsychopharmacology
- Suicide risk in Huntington's disease.Luigi Di Maio, Ferdinando Squitieri, G Napolitano, Giuseppe Campanella, James A. Trofatter, P. Michael Conneally · 1993 · Journal of Medical Genetics
- Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's diseaseWenzhen Duan, Qi Peng, Naoki Masuda, Eric Ford, Erik J. Tryggestad, Bruce Ladenheim, Ming Zhao, Jean Lud Cadet, John Wong, Christopher A. Ross · 2008 · Neurobiology of Disease
- Lithium Ameliorates Neurodegeneration, Suppresses Neuroinflammation, and Improves Behavioral Performance in a Mouse Model of Traumatic Brain InjuryFengshan Yu, Zhifei Wang, Flaubert Tchantchou, Chi‐Tso Chiu, Yumin Zhang, De‐Maw Chuang · 2011 · Journal of Neurotrauma
- HDAC inhibitor increases histone H3 acetylation and reduces microglia inflammatory response following traumatic brain injury in rats.Bin Zhang, E. West, Ken C. Van, Gene G. Gurkoff, Jia Zhou, Xiu-Mei Zhang, A. Kozikowski, Bruce G. Lyeth · 2008 · Brain Research
- The Wnt/β-Catenin Signaling Pathway as a Target in Drug DiscoveryFumi Takahashi‐Yanaga, Toshiyuki Sasaguri · 2007 · Journal of Pharmacological Sciences
- Lithium reduces apoptosis and autophagy after neonatal hypoxia–ischemiaQ Li, Huiqi Li, Karolina Roughton · 2010 · Cell Death and Disease
- Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington’s diseaseHuafeng Wei, Zheng‐Hong Qin, Vladimir V. Senatorov, Wenlin Wei, Y Wang, Yanning Qian, D M Chuang · 2001 · Neuroscience
- β-Catenin Overexpression in the Mouse Brain Phenocopies Lithium-Sensitive BehaviorsTodd D. Gould, Haim Einat, Kelley C. O’Donnell, Alyssa M. Picchini, Robert J. Schloesser, Husseini K. Manji · 2007 · Neuropsychopharmacology
- Lithium Plus Valproate Combination Therapy Versus Monotherapy for Relapse Prevention in Bipolar I Disorder (BALANCE): A Randomised Open-Label TrialThe BALANCE investigators and collaborators, John Richard Geddes, Guy M. Goodwin, Jennifer Rendell, Azorin Jm, Andrea Cipriani, Michael Joshua Ostacher, Richard Keith Morriss, Nicola C. Alder, Ed Juszczak · 2011 · FOCUS The Journal of Lifelong Learning in Psychiatry
- The Turn Motif Is a Phosphorylation Switch That Regulates the Binding of Hsp70 to Protein Kinase CTianyan Gao, Alexandra C. Newton · 2002 · Journal of Biological Chemistry
- Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factorsDiviya Sinha, Zhiyong Wang, Kathleen L. Ruchalski, Jerrold S. Levine, Selvi Krishnan, Wilfred Lieberthal, John H. Schwartz, Steven C. Borkan · 2004 · American Journal of Physiology-Renal Physiology
- Chapter 26 Role of Akt and Erk Signaling in the Neurogenesis Following Brain IschemiaNorifumi Shioda, Feng Han, Kohji Fukunaga · 2009 · International review of neurobiology
- Treatment with lithium carbonate does not improve disease progression in two different strains of SOD1 mutant miceChiara Pizzasegola, Ilaria Caron, Cristina Daleno, Anna Ronchi, Claudio Minoia, Maria Teresa Carrı̀, Caterina Bendotti · 2009 · Amyotrophic Lateral Sclerosis
- Antidepressant-like effect of the novel thiadiazolidinone NP031115 in miceAngelo Oscar Rosa, Manuella Pinto Kaster, Ricardo W. Binfaré, Susana Morales, Ester Martı́n-Aparicio, Marı́a Luisa Navarro-Rico, Ana Martı́nez, Miguel Medina, Antonio G. Garcı́a, Manuela G. López et al. · 2008 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Valproic acid attenuates blood–spinal cord barrier disruption by inhibiting matrix metalloprotease‐9 activity and improves functional recovery after spinal cord injuryJee Y. Lee, Hwang S. Kim, Hye Young Choi, Tae H. Oh, Bong Gun Ju, Tae Young Yune · 2012 · Journal of Neurochemistry
- Valproic Acid–Mediated Neuroprotection and Regeneration in Injured Retinal Ganglion CellsJulia Biermann, Philippe Grieshaber, Ulrich Goebel, Gottfried Martin, Solon Thanos, Simone Di Giovanni, Wolf Alexander Lagrèze · 2010 · Investigative Ophthalmology & Visual Science
- Valproic acid induces functional heat‐shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylationZoya Marinova, Ming Ren, Jens R. Wendland, Yan Leng, Min‐Huei Liang, Shigeru Yasuda, Peter R. Leeds, De‐Maw Chuang · 2009 · Journal of Neurochemistry
- Inhibition of Wnt signaling, modulation of Tau phosphorylation and induction of neuronal cell death by DKK1Carla Scali, Filippo Caraci, Marco Gianfriddo, Enrica Diodato, Renza Roncarati, Giuseppe Pollio, Giovanni Gaviraghi, Agata Copani, Ferdinando Nicoletti, Georg C. Terstappen et al. · 2006 · Neurobiology of Disease
- Mesenchymal Stem Cells Primed With Valproate and Lithium Robustly Migrate to Infarcted Regions and Facilitate Recovery in a Stroke ModelLi‐Kai Tsai, Zhifei Wang, Jeeva Munasinghe, Yan Leng, Peter R. Leeds, De‐Maw Chuang · 2011 · Stroke
- High resolution methylation analysis of the FMR1 gene trinucleotide repeat region in fragile X syndromeLan K. Hornstra, David Lee Nelson, Stephen T. Warren, Thomas P. Yang · 1993 · Human Molecular Genetics
- β-Amyloid peptide-induced death of PC 12 cells and cerebellar granule cell neurons is inhibited by long-term lithium treatmentHuafeng Wei, Peter R. Leeds, Yanning Qian · 2000 · European Journal of Pharmacology
- Abnormal SMN1 gene copy number is a susceptibility factor for amyotrophic lateral sclerosisPhilippe Corcia, Véronique Mayeux‐Portas, Jawad Khoris, Bertrand de Toffol, Alain Autret, J.P. Müh, William Camu, Christian Robert Andres · 2002 · Annals of Neurology
- Prevention of MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) dopaminergic neurotoxicity in mice by chronic lithium: involvements of Bcl-2 and BaxZaher Arraf, Moussa B. H. Youdim · 2004 · Neuropharmacology
- Mutant Huntingtin reduces HSP70 expression through the sequestration of NF‐Y transcription factorTomoyuki Yamanaka, Haruko Miyazaki, Fumitaka Oyama, Masaru Kurosawa, Chika Washizu, Hiroshi Doi, Nobuyuki Nukina · 2008 · The EMBO Journal
- Regulation of Cortical Interneurons by Neurotrophins: From Development to Cognitive DisordersNewton H. Woo, Bai Lu · 2006 · The Neuroscientist
- BRAN AND BLOOD-LIPIDSI. Persson, KN. Raby, Peter Fønss-Bech, Eva N. Jensen · 1975 · The Lancet
- Randomized sequential trial of valproic acid in amyotrophic lateral sclerosisSanne Piepers, Jan Herman Veldink, Sonja W. de Jong, Ingeborg van der Tweel, W. Ludo van der Pol, Esther V. Uijtendaal, Helenius Jurgen Schelhaas, Hans Scheffer, Marianne de Visser, J.M.B.V. de Jong et al. · 2009 · Annals of Neurology
- Lithium regulates hippocampal neurogenesis by ERK pathway and facilitates recovery of spatial learning and memory in rats after transient global cerebral ischemiaXuebo Yan, Hailong Hou, Lin-Min Wu, Ji Liu, Jiang‐Ning Zhou · 2007 · Neuropharmacology
- Effects of lithium on oxidative stress parameters in healthy subjectsRodrigo Machado‐Vieira · 2011 · Molecular Medicine Reports
- Homozygous deletion of the survival motor neuron 2 gene is a prognostic factor in sporadic ALSJan Herman Veldink, Leonard H. van den Berg, Jan Maarten Cobben, Rein P. Stulp, J.M.B.V. de Jong, Oscar J.M. Vogels, Frank Baas, John H. J. Wokke, Hans Scheffer · 2001 · Neurology
- Neuropsychological effects of valproate in traumatic brain injuryS.S. Dikmen, Joan Machamer, H. Richard Winn · 2000 · Neurology
- Chronic lithium treatment decreases tau lesions by promoting ubiquitination in a mouse model of tauopathiesHanae Nakashima, Takeshi Ishihara, S. Pilar Suguimoto, Osamu Yokota, Etsuko Oshima, Aki Kugo, Seishi Terada, Takashi Hamamura, John Q. Trojanowski, Virginia M.‐Y. Lee et al. · 2005 · Acta Neuropathologica
- Long-Term Treatment with Lithium Alleviates Memory Deficits and Reduces Amyloid-β Production in an Aged Alzheimer's Disease Transgenic Mouse ModelXin Zhang, Xin Heng, Ting Li, Lixi Li, Dehua Yang, Xiaojie Zhang, Yunlan Du, Rachelle Smith Doody, Weidong Le · 2011 · Journal of Alzheimer s Disease
- Neuroprotective effects of valproic acid following transient global ischemia in ratsAiguo Xuan, Dahong Long, Jianhua Li, Weidong Ji, Le-Peng Hong, Meng Zhang, Wenjuan Zhang · 2012 · Life Sciences
- Cytoprotection by lithium and valproate varies between cell types and cellular stressesJustin S. Lai, Chunnian Zhao, Jerry J. Warsh, Peter P. Li · 2006 · European Journal of Pharmacology
- Recent advances in fragile X: a model for autism and neurodegenerationRandi Jenssen Hagerman, Michele Y. Ono, Paul J. Hagerman · 2005 · Current Opinion in Psychiatry
- Regulation of tau phosphorylation and protection against β‐amyloid‐induced neurodegeneration by lithium. Possible implications for Alzheimer's diseaseGema Alvarez, Juan Ramón Muñoz-Montaño, Jorgina Satrústegui, Jesús Ávila, Elena Bogónez, Javier Díaz‐Nido · 2002 · Bipolar Disorders
- Intracellular mechanisms underlying aluminum-induced apoptosis in rabbit brainJ Savory · 2003 · Journal of Inorganic Biochemistry
- Chronic Valproate Treatment Enhances Postischemic Angiogenesis and Promotes Functional Recovery in a Rat Model of Ischemic StrokeZhifei Wang, Li‐Kai Tsai, Jeeva Munasinghe, Yan Leng, Emily Bame Fessler, Fairouz L. Chibane, Peter R. Leeds, De‐Maw Chuang · 2012 · Stroke
- Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibitionKidd, Sarah K., Schneider, Jay S. · 2010 · Brain Research
- The regulation of phosphorylation of τ in SY5Y neuroblastoma cells: the role of protein phosphatasesToshihisa Tanaka, Jun Zhong, Khalid Iqbal, Ekkhart Trenkner, Inge Grundke · 1998 · FEBS Letters
- Short-term lithium treatment promotes neuronal survival and proliferation in rat striatum infused with quinolinic acid, an excitotoxic model of Huntington's diseaseVladimir V. Senatorov, M Ren, Hirohiko Kanai, Huafeng Wei, D M Chuang · 2003 · Molecular Psychiatry
- Valproic acid increases white matter repair and neurogenesis after strokeXuesheng Liu, Michael Chopp, Haifa Kassis, Longfei Jia, Ann Hozeska‐Solgot, R.L. Zhang, C. Chen, Y.S. Cui, Zhixian Zhang · 2012 · Neuroscience
- Vascular endothelial growth factor protects spinal cord motoneurons against glutamate‐induced excitotoxicity via phosphatidylinositol 3‐kinaseLaia Tolosa, Margalida Mir, Víctor J. Asensio, Gabriel Olmos, Jerònia Lladó · 2007 · Journal of Neurochemistry
- Lithium Regulates Glycogen Synthase Kinase-3β in Human Peripheral Blood Mononuclear Cells: Implication in the Treatment of Bipolar DisorderXiaohua Li, Ari B. Friedman, Wawa Zhu, Li Wang, Sherer Boswell, Roberta May, Lori L. Davis, Richard Scott Jope · 2006 · Biological Psychiatry
- Antiepileptic drug use in women of childbearing ageKimford J. Meador, Patricia E. Penovich, Gus A. Baker et al. · 2009 · Epilepsy & Behavior
- Adult human hematopoietic stem cells produce neurons efficiently in the regenerating chicken embryo spinal cordÓlafur E. Sigurjónsson, Marie‐Claude Perreault, TORSTEIN EGELAND, Joel Clinton Glover · 2005 · Proceedings of the National Academy of Sciences
- Lithium Reduces BACE1 Overexpression, Beta Amyloid Accumulation, and Spatial Learning Deficits in Mice with Traumatic Brain InjuryFengshan Yu, Yumin Zhang, De‐Maw Chuang · 2012 · Journal of Neurotrauma
- INCOMPRESSIBLE VESSELSLeslie Klenerman, J D Lewis · 1976 · The Lancet
- SMN genotypes producing less SMN protein increase susceptibility to and severity of sporadic ALSJan Herman Veldink, Sandra Kalmijn, Annemarie H. van der Hout, Henny H. Lemmink, Geert Jan Groeneveld, Chantal Lummen, Hans Scheffer, John H. J. Wokke, Leonard H. van den Berg · 2005 · Neurology
- Lithium-Mediated Long-Term Neuroprotection in Neonatal Rat Hypoxia–Ischemia is Associated with Antiinflammatory Effects and Enhanced Proliferation and Survival of Neural Stem/Progenitor CellsHongfu Li, Qian Li, Xiaonan Du, Yanyan Sun, Xiaoyang Wang, Guido Kroemer, Klas Blomgren, Changlian Zhu · 2011 · Journal of Cerebral Blood Flow & Metabolism
- Proteasomal dysfunction in aging and Huntington diseaseXiao‐Jiang Li, Shihua Li · 2010 · Neurobiology of Disease
- Anxiety and physical illness in the elderly.J M Turnbull · 1989 · PubMed
- Lithium Chloride Reinforces the Regeneration-Promoting Effect of Chondroitinase ABC on Rubrospinal Neurons after Spinal Cord InjuryYick, Leung-Wah, So, Kwok-Fai, Cheung, Pik-To, Wu, Wu-Tian · 2004 · Journal of Neurotrauma
- Functional Repression of cAMP Response Element in 6-Hydroxydopamine-treated Neuronal Cells*E. M. Chalovich, Jian-Hui Zhu, John Caltagarone, R. Bowser, Charleen T. Chu · 2006 · Journal of Biological Chemistry
- Proton magnetic resonance spectroscopy in Huntington's disease: Evidence in favour of the glutamate excitotoxic theory?Simon David Taylor-Robinson, RobertA. Weeks, D. J. Bryant, Janet Sargentoni, ClaudeD. Marcus, A. E. Harding, David James Brooks · 1996 · Movement Disorders
- Newer anticonvulsants in the treatment of bipolar disorder.Lakshmi N. Yatham · 2004 · PubMed
- Valproate inhibits oxidative damage to lipid and protein in primary cultured rat cerebrocortical cellsJunfeng Wang, Joseph E. Azzam, Lionel Trevor Young · 2003 · Neuroscience
- A Placebo-Controlled Trial of Valproate for Agitation and Aggression in Alzheimer’s DiseaseNathan Herrmann, Krista L. Lanctôt, Lana S. Rothenburg, Goran M. Eryavec · 2006 · Dementia and Geriatric Cognitive Disorders
- Role of glycogen synthase kinase-3β in early depressive behavior induced by mild traumatic brain injuryMoran Shapira, Avital Licht-Murava, Anat Milman, Chaim G. Pick, Esther Shohami, Hagit Eldar-Finkelman · 2006 · Molecular and Cellular Neuroscience
- Disorders of reproduction in patients with epilepsy: Antiepileptic drug related mechanismsJouko I. T. Isojärvi · 2008 · Seizure
- Lithium Ameliorates HIV-gp120-Mediated NeurotoxicityIan Everall · 2002 · Molecular and Cellular Neuroscience
- Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology.Leroy, Karelle, Ando, Kunie, Héraud, Céline, Yilmaz, Zehra, Authelet, Michèle, Boeynaems, Jean-Marie, Buée, Luc, De Decker, Robert, Brion, Jean-Pierre · 2010 · Journal of Alzheimer's Disease
- Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2T Hiroi, Huafeng Wei, Christopher J. Hough, Peter R. Leeds, D M Chuang · 2005 · The Pharmacogenomics Journal
- Mode of Action: Inhibition of Histone Deacetylase, Altering WNT-Dependent Gene Expression, and Regulation of Beta-Catenin—Developmental Effects of Valproic AcidJeanette A. Wiltse · 2005 · Critical Reviews in Toxicology
- Lithium stimulates progenitor proliferation in cultured brain neuronsRyota Hashimoto, Vladimir V. Senatorov, Hirohiko Kanai, Peter R. Leeds, D M Chuang · 2003 · Neuroscience
- A double‐blind, parallel, multicenter comparison of <scp>L</scp>‐acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boysTorrioli, M. Giulia, Vernacotola, Silvia, Peruzzi, Laura, Tabolacci, Elisabetta, Mila, Montserrat, Militerni, Roberto, Musumeci, Sebastiano, Ramos, Feliciano J., Frontera, Marìa, Sorge, Giovanni et al. · 2008 · American Journal of Medical Genetics Part A
- Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3β transgenesJanet Brownlees, Nicholas G. Irving, Jean‐Pierre Brion, Barry J. M. Gibb, Uta Wagner, James Robert Woodgett, Christopher C.J. Miller · 1997 · Neuroreport
- Lithium enhances proliferation and neuronal differentiation of neural progenitor cells in vitro and after transplantation into the adult rat spinal cordHuanxing Su, Tak‐Ho Chu, Wutian Wu · 2007 · Experimental Neurology
- The Patents-Based Pharmaceutical Development ProcessJohn H. Barton, Ezekiel J. Emanuel · 2005 · JAMA
- Lithium and dementia: A preliminary studyTakeshi Terao, Hideki Nakano, Yoshiaki Inoue, Tatsuya Okamoto, Jun Nakamura, Noboru Iwata · 2006 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Lithium and hematology: established and proposed usesFocosi, Daniele, Azzarà, Antonio, Kast, Richard Eric, Carulli, Giovanni, Petrini, Mario · 2009 · Journal of Leukocyte Biology
- Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injuryNa’ama A. Shein, Nikolaos Grigoriadis, Alexander G. Alexandrovich, Constantina Simeonidou, Athanasios I. Lourbopoulos, Eleni Polyzoidou, Victoria Trembovler, Paolo Mascagni, Charles Anthony Dinarello, Esther Shohami · 2009 · The FASEB Journal
- Potential autophagy enhancers attenuate rotenone-induced toxicity in SH-SY5YNian Xiong, Min Jia, Chung‐Kuan Chen, Jing Xiong, Z. Zhang, J. Huang, L. Hou, Hecheng Yang, Xin Cao, Zhihou Liang et al. · 2011 · Neuroscience
- Expression of Vascular Endothelial Growth Factor and Its Receptors in the Central Nervous System in Amyotrophic Lateral SclerosisAlice Brockington, Stephen B. Wharton, Malee S Fernando, Catherine Gelsthorpe, Lynne Baxter, Paul G. Ince, Claire E. Lewis, Pamela J. Shaw · 2006 · Journal of Neuropathology & Experimental Neurology
- Support of Retinal Ganglion Cell Survival and Axon Regeneration by Lithium through a Bcl-2-Dependent MechanismXizhong Huang, Da-Yu Wu, Guang Chen, Husseini K. Manji, Dong Feng Chen · 2003 · Investigative Ophthalmology & Visual Science
- Lithium carbonate in amyotrophic lateral sclerosis: Lack of efficacy in a dose-finding trialChiò, A., Borghero, G., Calvo, A., Capasso, M., Caponnetto, C., Corbo, M., Giannini, F., Logroscino, G., Mandrioli, J., Marcello, N. et al. · 2010 · Neurology
- Role of ubiquitin–proteasome-mediated proteolysis in nervous system diseaseAshok N. Hegde, Sudarshan C. Upadhya · 2010 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
- Differential Display PCR Reveals Novel Targets for the Mood-Stabilizing Drug Valproate Including the Molecular Chaperone GRP78Junfeng Wang, Christopher D. Bown, L. Trevor Young · 1999 · Molecular Pharmacology
- Valproate protects the retina from endoplasmic reticulum stress-induced apoptosis after ischemia–reperfusion injuryZhenzhen Zhang, Nianting Tong, Yuanyuan Gong, Qinghua Qiu, Lili Yin, Xiu-Hong Lv, Xingwei Wu · 2011 · Neuroscience Letters
- Association of the putative susceptibility gene, transient receptor potential protein melastatin type 2, with bipolar disorderChun Di Xu, Fabio M. Macciardi, Peter P. Li, Il‐Sang Yoon, R.G. Cooke, Bronwen Hughes, Sagar V. Parikh, Roger S. McIntyre, James L. Kennedy, Jerry J. Warsh · 2005 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics