Epigenetic Regulation of Aging in Honeybee Workers
Abstract
Aging and longevity are complex life history traits that are influenced by both genes and environment and exhibit significant phenotypic plasticity in a broad range of organisms. A striking example of this plasticity is seen in social insects, such as ants and bees, where different castes can have very different life spans. In particular, the honeybee worker offers an intriguing example of environmental control on aging rate, because workers are conditionally sterile and display very different aging patterns depending on which temporal caste they belong to (hive bee, forager, or a long-lived caste capable of surviving for several months on honey alone). The ubiquitous yolk protein vitellogenin appears to play a key role in the regulatory circuitry that controls this variation. Here we outline the current understanding of the relation between vitellogenin and somatic maintenance in honeybee workers, and how this relation can be understood in a life history context.
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In controlled laboratory settings, social contact is linked to longer lifespan across many social species, including insects, rodents, and primates.
“Even in controlled laboratory environments (where external threats to survival are absent), the presence of social contact is associated with increased lifespan across a range of social species including honeybees, ants, Drosophila melanogaster22,23, mice24,25, and rats26–28, as well as in free-ranging groups of macaques29, and baboons30.”
From Neural mechanisms of social homeostasis (2019) · cites this paper as [23]
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- Authors
- Omholt, S. W., & Amdam, G. V.
- Affiliations
- University of California, Davis (US)
- Venue
- Science of Aging Knowledge Environment
- Published
- 2004-06-30
- Volume
- 2004
- Issue
- 26
- Pages
- pe28-pe28
- ISSN
- 1539-6150 (ISSN-L)
- OpenAlex
- W1969605870
- Cited by
- 79
- References
- 34
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 6 · 2023: 4 · 2022: 5 · 2021: 3 · 2020: 2 · 2019: 3 · 2018: 2 · 2017: 1 · 2016: 3 · 2014: 3 · 2013: 8 · 2012: 2
- FWCI
- 0.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science of Aging Knowledge Environment (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Insect and Arachnid Ecology and Behavior
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Animal Behavior and Reproduction
- Keywords
- epigenetic regulation, aging, honeybee workers, vitellogenin, longevity, life history, somatic maintenance, social insects
- MeSH terms
- Aging, Animals, Bees, Behavior, Animal, Biological Evolution, Feeding Behavior, Female, Social Behavior, Species Specificity, Vitellogenins, Epigenesis, Genetic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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