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The microbiome of uncontacted Amerindians
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Fecal, oral, and skin biomes of isolated Amerindians show higher human bacterial diversity including antibiotic resistance genes.
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“Although no living population today carries an ancestral microbiome, comparison studies of non-Western and Western populations show significant differences in the relative abundances of common phyla and a much greater species diversity in non-Western populations [126,127].”
From Polycystic Ovary Syndrome: An Evolutionary Adaptation to Lifestyle and the Environment (2022) · cites this paper as [127]
Experimental — accuracy not yet measuredIn the citing paper
“The gut microbiota of eight hunter–gatherer or rural farming populations in various parts of the world showed increased bacterial diversity compared with those of Western populations19,40,52–55.”
From Diet–microbiota interactions as moderators of human metabolism (2016) · cites this paper as [55]
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Metadata
- Authors
- Clemente, J. C., Pehrsson, E. C., Blaser, M. J., Sandhu, K., Gao, Z., Wang, B., Magris, M., Hidalgo, G., Contreras, M., Noya-Alarcón, Ó., Lander, O., McDonald, J., Cox, M., Walter, J., Oh, P. L., Ruiz, J. F., Rodriguez, S., Shen, N., Song, S. J., Metcalf, J., Knight, R., Dantas, G., & Dominguez-Bello, M. G.
- Affiliations
- Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
- Washington University in St. Louis (US)
- United States Department of Veterans Affairs (US)
- New York University (US)
- Amazonic Center for Research and Control of Tropical Diseases (CAICET), Puerto Ayacucho 7101, Venezuela.
- Venezuelan Institute for Scientific Research, Caracas 1020-A, Venezuela.
- Universidad Central de Venezuela (VE)
- AnMed Health (US)
- University of Nebraska–Lincoln (US)
- University of Puerto Rico at Río Piedras (PR)
- Icahn School of Medicine at Mount Sinai (US)
- University of Colorado Boulder (US)
- Howard Hughes Medical Institute (US)
- New York University School of Medicine, New York, NY 10016, USA.
- Corresponding author
- Pehrsson, Erica C.
- Sandhu, Kuldip
- Walter, Jens
- Knight, Rob
- ORCID
- Venue
- Science Advances
- Published
- 2015-04-03
- Volume
- 1
- Issue
- 3
- ISSN
- 2375-2548 (ISSN-L)
- PMC
- PMC4517851
- OpenAlex
- W1986189475
- Cited by
- 851
- References
- 74
- Citations by year
- 2026: 35 · 2025: 55 · 2024: 59 · 2023: 72 · 2022: 81 · 2021: 88 · 2020: 90 · 2019: 103 · 2018: 77 · 2017: 72 · 2016: 86 · 2015: 31
- FWCI
- 38.52
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc
- Locations
- Science Advances (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Digital Commons@Becker (Washington University School of Medicine) (submittedVersion)
- Rutgers University Community Repository (Rutgers University) (submittedVersion)
- Lincoln (University of Nebraska) (submittedVersion, cc-by-nc)
- eScholarship (California Digital Library) (submittedVersion)
- eScholarship (California Digital Library) (submittedVersion, cc-by-nc)
- Funders
- C&D Research Fund (ID0EWFBG929)
- Emch Research Fund (ID0EBMBG930)
- NIH SCORE-PES RISE (ID0EMSBG931, 2R25GM061151-13)
- SUCCESS (ID0EZYBG932)
- Leona M. and Harry B. Helmsley Charitable Trust (ID0ET1BG933)
- NIH NIDDK (ID0EN3BG934, DK062429)
- NAKFI Synthetic Biology (ID0EJ5BG935, SB2, ID0ECAAI936)
- NIH Director’s New Innovator Award (ID0EYBAI937, NIDDK DP2-DK098089)
- NIH NIGMS (ID0EQDAI938, R01-GM099538)
- Washington University I-CARES (ID0EIFAI939)
- NIH NIAMS (ID0E5GAI940, UH2AR057506)
- Diane Belfer Program for Human Microbial Ecology (ID0EYIAI941)
- NDSEG (ID0EQKAI942)
- Howard Hughes Medical Institute (ID0EEMAI943)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Microbiology (medical) › Antibiotic Resistance in Bacteria
- Physical Sciences › Environmental Science › Ecology › Microbial Community Ecology and Physiology
- Keywords
- human microbiome, resistome, antibiotic resistance genes, Yanomami, isolated populations, Westernization, bacterial diversity, synthetic antibiotics, gut microbiota, oral microbiota, skin microbiome
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