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Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti–COVID-19 drug design
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A multidisciplinary approach yields novel inhibitors and reveals substrate specificity, structure, and mechanisms of CoV-2 PLpro.
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Metadata
- Authors
- Rut, W., Lv, Z., Zmudzinski, M., Patchett, S., Nayak, D., Snipas, S. J., El Oualid, F., Huang, T. T., Bekes, M., Drag, M., & Olsen, S. K.
- Venue
- Science Advances
- Published
- 2020-10-16
- Volume
- 6
- Issue
- 42
- ISSN
- 2375-2548 (ISSN-L)
- OpenAlex
- W3092736134
- Cited by
- 459
- References
- 45
- FWCI
- 10.23
- Type
- journal article
- Language
- en
- Open access
- gold
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