The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
RNA-Dependent RNA Polymerases, Viruses, and RNA Silencing
Abstract
Most viruses have RNA genomes that are replicated and transcribed into messenger RNA by viral RNA–dependent RNA polymerases (RdRps), usually in concert with other viral and host factors. Many, if not most, eukaryotes also encode putative RdRps that have been implicated in sequence-specific, RNA-triggered gene silencing. Although the viral and cellular RdRps have no sequence homology, they share functional similarities such as copying messenger RNA templates and intercellular spread of the amplified sequences. Better understanding of viral and host RdRps will improve our ability to control viruses and to use RNA silencing and viruses as tools for research, biotechnology, and medicine.
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Cites
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
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Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding
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On the Role of RNA Amplification in dsRNA-Triggered Gene Silencing
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Induction and Suppression of RNA Silencing by an Animal Virus
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Cited by
Tolerance for mutations and chemical modifications in a siRNA
Amarzguioui, M. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg147 · Cited by 534
Common and unique features of viral RNA-dependent polymerases
te Velthuis, A. J. W. (2014) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1695-z · Cited by 275
Serva, S., & Nagy, P. D. (2006) · Journal of Virology · doi:10.1128/jvi.80.5.2162-2169.2006 · Cited by 181
Uyaguari-Diaz, M. I., Chan, M., Chaban, B. L., Croxen, M. A., Finke, J. F., Hill, J. E., Peabody, M. A., Van Rossum, T., Suttle, C. A., Brinkman, F. S. L., et al. (2016) · Microbiome · doi:10.1186/s40168-016-0166-1 · Cited by 104
Making of Viral Replication Organelles by Remodeling Interior Membranes
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Metadata
- Authors
- Ahlquist, P.
- Venue
- Science
- Published
- 2002-05-17
- Volume
- 296
- Issue
- 5571
- Pages
- 1270-1273
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2145665475
- Cited by
- 462
- References
- 46
- FWCI
- 48.25
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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