The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Systematic Identification of Pathways That Couple Cell Growth and Division in Yeast
Abstract
Size homeostasis in budding yeast requires that cells grow to a critical size before commitment to division in the late prereplicative growth phase of the cell cycle, an event termed Start. We determined cell size distributions for the complete set of ∼6000 Saccharomyces cerevisiae gene deletion strains and identified ∼500 abnormally small ( whi ) or large ( lge ) mutants. Genetic analysis revealed a complex network of newly found factors that govern critical cell size at Start, the most potent of which were Sfp1, Sch9, Cdh1, Prs3, and Whi5. Ribosome biogenesis is intimately linked to cell size through Sfp1, a transcription factor that controls the expression of at least 60 genes implicated in ribosome assembly. Cell growth and division appear to be coupled by multiple conserved mechanisms.
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Cites
Cluster analysis and display of genome-wide expression patterns
Eisen, M. B., Spellman, P. T., Brown, P. O., & Botstein, D. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.14863 · Cited by 16,184
Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants
Tong, A. H. Y., Evangelista, M., Parsons, A. B., Xu, H., Bader, G. D., Pagé, N., Robinson, M., Raghibizadeh, S., Hogue, C. W. V., Bussey, H., et al. (2001) · Science · doi:10.1126/science.1065810 · Cited by 2,138
Self-citationCoordination of growth with cell division in the yeast
JOHNSTON, G., PRINGLE, J., & HARTWELL, L. (1977) · Experimental Cell Research · doi:10.1016/0014-4827(77)90154-9 · Cited by 827
Cited by
Influence of Metabolism on Epigenetics and Disease
Kaelin, W. G., & McKnight, S. L. (2013) · Cell · doi:10.1016/j.cell.2013.03.004 · Cited by 920
Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control
Loewith, R., & Hall, M. N. (2011) · Genetics · doi:10.1534/genetics.111.133363 · Cited by 910
Zhao, R., Davey, M., Hsu, Y.-C., Kaplanek, P., Tong, A., Parsons, A. B., Krogan, N., Cagney, G., Mai, D., Greenblatt, J., et al. (2005) · Cell · doi:10.1016/j.cell.2004.12.024 · Cited by 819
Integrative Analysis of Cell Cycle Control in Budding Yeast
Chen, K. C., Calzone, L., Csikasz-Nagy, A., Cross, F. R., Novak, B., & Tyson, J. J. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e03-11-0794 · Cited by 632
Exploration of Essential Gene Functions via Titratable Promoter Alleles
Mnaimneh, S., Davierwala, A. P., Haynes, J., Moffat, J., Peng, W.-T., Zhang, W., Yang, X., Pootoolal, J., Chua, G., Lopez, A., et al. (2004) · Cell · doi:10.1016/j.cell.2004.06.013 · Cited by 604
Metadata
- Authors
- Jorgensen, P., Nishikawa, J. L., Breitkreutz, B.-J., & Tyers, M.
- Venue
- Science
- Published
- 2002-07-19
- Volume
- 297
- Issue
- 5580
- Pages
- 395-400
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2088127501
- Cited by
- 768
- References
- 3
- FWCI
- 14.04
- Type
- journal article
- Language
- en
- Open access
- closed
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