The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
"Stemness": Transcriptional Profiling of Embryonic and Adult Stem Cells
Abstract
The transcriptional profiles of mouse embryonic, neural, and hematopoietic stem cells were compared to define a genetic program for stem cells. A total of 216 genes are enriched in all three types of stem cells, and several of these genes are clustered in the genome. When compared to differentiated cell types, stem cells express a significantly higher number of genes (represented by expressed sequence tags) whose functions are unknown. Embryonic and neural stem cells have many similarities at the transcriptional level. These results provide a foundation for a more detailed understanding of stem cell biology.
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Cites
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Genomic Expression Programs in the Response of Yeast Cells to Environmental Changes
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Changing potency by spontaneous fusion
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Accuracy and calibration of commercial oligonucleotide and custom cDNA microarrays
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Cited by
Cahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., Xing, Y., Lubischer, J. L., Krieg, P. A., Krupenko, S. A., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4178-07.2008 · Cited by 3,129
“Many other transcription factors such as Sox2, Pax6, Id1, and Id3, thought to be enriched in progenitor cells (Ramalho-Santos et al., 2002), were expressed at A: Astrocyte enriched signaling pathways C: Neuron enriched signaling pathways P-value Signaling Pathway P-value Signaling Pathway 1 1.”
BackgroundKiel, M. J., Yilmaz, Ö. H., Iwashita, T., Yilmaz, O. H., Terhorst, C., & Morrison, S. J. (2005) · Cell · doi:10.1016/j.cell.2005.05.026 · Cited by 3,168
MAQC Consortium, Shi, L., Shi, L., Reid, L. H., Jones, W. D., Shippy, R., Warrington, J. A., Baker, S. C., Collins, P. J., de Longueville, F., et al. (2006) · Nature Biotechnology · doi:10.1038/nbt1239 · Cited by 2,126
Sato, N., Meijer, L., Skaltsounis, L., Greengard, P., & Brivanlou, A. H. (2004) · Nature Medicine · doi:10.1038/nm979 · Cited by 2,109
Defining the Epithelial Stem Cell Niche in Skin
Tumbar, T., Guasch, G., Greco, V., Blanpain, C., Lowry, W. E., Rendl, M., & Fuchs, E. (2004) · Science · doi:10.1126/science.1092436 · Cited by 2,031
Metadata
- Authors
- Ramalho-Santos, M., Yoon, S., Matsuzaki, Y., Mulligan, R. C., & Melton, D. A.
- Venue
- Science
- Published
- 2002-10-18
- Volume
- 298
- Issue
- 5593
- Pages
- 597-600
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2001627351
- Cited by
- 1,709
- References
- 7
- FWCI
- 48.92
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ramalho-Santos, M., Yoon, S., Matsuzaki, Y., Mulligan, R. C., & Melton, D. A. (2002). "Stemness": Transcriptional Profiling of Embryonic and Adult Stem Cells. Science. https://doi.org/10.1126/science.1072530
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.