TGF-ß Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia

Bhowmick, Neil A., Chytil, Anna, Plieth, David, Gorska, Agnieszka E., Dumont, Nancy, Shappell, Scott, Washington, M. Kay, Neilson, Eric G. +1 more·2004·Science

DOI 10.1126/science.1090922

Cited by (1,001)

Items 301–400 of 1,001

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Chunyu Zhang, Li Fu, Jianhua Fu, Liang Hu, Hong Yang, Tie-Hua Rong, Yan Li, Haibo Liu, Song-Bin Fu, Yi-Xin Zeng et al. · 2009 · Clinical Cancer Research
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Nickoloff, Brian J., Ben-Neriah, Yinon, Pikarsky, Eli · 2005 · Journal of Investigative Dermatology
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Eloïse M. Grasset, Thomas Bertero, Alexandre Bozec, Jonas Friard, Isabelle Bourget, Sabrina Pisano, Margaux Lecacheur, Majdi Maiel, Caroline Bailleux, Alexander Emelyanov et al. · 2018 · Cancer Research
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Platel, Valentin, Faure, Sébastien, Corre, Isabelle, Clere, Nicolas · 2019 · Journal of Oncology
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