Insulin Signaling in Health and Disease

Cited by (732)

Items 201–300 of 732

1. Identification of Insulin Receptor Substrate 1 Serine/Threonine Phosphorylation Sites Using Mass Spectrometry Analysis: Regulatory Role of Serine 1223
   Moulun Luo, Sara M. Reyna, Lishan Wang, Zheng-Ping Yi, Christopher A. Carroll, Lily Dong, Paul R. Langlais, Susan T. Weintraub, Lawrence J. Mandarino · 2005 · Endocrinology
2. Angiotensin receptor blockers in the treatment of NASH/NAFLD: Could they be a first-class option?
   Eugen Florin Georgescu · 2008 · Advances in Therapy
3. Dietary Reversal Ameliorates Short- and Long-Term Memory Deficits Induced by High-fat Diet Early in Life
   Catrina Sims‐Robinson, Anna Bakeman, Elizabeth S. Bruno, Samuel Jackson, Rebecca Glasser, Geoffrey G. Murphy, Eva L. Feldman · 2016 · PLoS ONE
4. Neurotrophins and Other Growth Factors in the Pathogenesis of Alzheimer’s Disease
   Tadahiro Numakawa, Ryutaro Kajihara · 2023 · Life
5. Hormonal regulation of metabolism—recent lessons learned from insulin and estrogen
   Zhipeng Tao, Zhiyong Cheng · 2023 · Clinical Science
6. The role of insulin signaling in the development of β-cell dysfunction and diabetes
   Qinghua Wang, Tianru Jin · 2009 · Islets
7. Genetic variation in IGF1, IGFBP3, IRS1, IRS2 and risk of breast cancer in women living in Southwestern United States
   Martha L. Slattery, Carol Sweeney, Roger K. Wolff, Jennifer S. Herrick, Kathy B. Baumgartner, Anna R. Giuliano, T. Byers · 2006 · Breast Cancer Research and Treatment
8. Early responses of insulin signaling to high-carbohydrate and high-fat overfeeding
   Rebecca Adochio, J. Wayne Leitner, Karen Gray, Boris Draznin, Marc‐André Cornier · 2009 · Nutrition & Metabolism
9. Lipid metabolism in Alzheimer’s disease
   Zhu, Tian-Bi, Zhang, Zhao, Luo, Piao, Wang, Sha-Sha, Peng, Ye, Chu, Shi-Feng, Chen, Nai-Hong · 2019 · Brain Research Bulletin
10. Molecular basis of insulin resistance: the role of IRS and Foxo1 in the control of diabetes mellitus and its complications
    Shaodong Guo · 2013 · Drug Discovery Today Disease Mechanisms
11. Differential regulation of IGF-I and IGF-II gene expression in skeletal muscle cells
    Shuang Jiao, Hongxia Ren, Yun Li, Jianfeng Zhou, Cunming Duan, Ling Lü · 2012 · Molecular and Cellular Biochemistry
12. Oleanolic acid supplement attenuates liquid fructose-induced adipose tissue insulin resistance through the insulin receptor substrate-1/phosphatidylinositol 3-kinase/Akt signaling pathway in rats
    Ying Li, Jianwei Wang, Tieguang Gu, Johji Yamahara, Yuhao Li · 2014 · Toxicology and Applied Pharmacology
13. The good and the bad in the link between insulin resistance and vascular calcification
    Gian Paolo Fadini, Paolo Pauletto, Angelo Avogaro, Marcello Rattazzi · 2007 · Atherosclerosis
14. Effects of Moringa oleifera aqueous leaf extract in alloxan induced diabetic mice
    Muobarak J. Tuorkey · 2016 · Interventional Medicine and Applied Science
15. Exercise and Glycemic Control: Focus on Redox Homeostasis and Redox-Sensitive Protein Signaling
    Lewan Parker, Christopher S. Shaw, Nigel K. Stepto, Itamar Levinger · 2017 · Frontiers in Endocrinology
16. Metabolic and Energy Imbalance in Dysglycemia-Based Chronic Disease
    Sanjay Kalra, AG Unnikrishnan, Manash Pratim Baruah, Rakesh Kumar Sahay, Ganapathi Bantwal · 2021 · Diabetes Metabolic Syndrome and Obesity
17. Post‐synaptic density perturbs insulin‐induced Kv1.3 channel modulation via a clustering mechanism involving the SH3 domain
    D. R. Marks, Debra Ann Fadool · 2007 · Journal of Neurochemistry
18. Aging: gene silencing or gene activation?
    Stanislaw Rajmund Burzynski · 2004 · Medical Hypotheses
19. Cucurbitane Triterpenoids from the Fruits of Momordica Charantia Improve Insulin Sensitivity and Glucose Homeostasis in Streptozotocin‐Induced Diabetic Mice
    Joo‐Hui Han, Nguyễn Quốc Tuấn, Min‐Ho Park, Khong Trong Quan, Joonseok Oh, Kyung‐Sun Heo, MinKyun Na, Chang‐Seon Myung · 2018 · Molecular Nutrition & Food Research
20. Exosomal lipids induce human pancreatic tumoral MiaPaCa-2 cells resistance through the CXCR-4SDF-1α signaling axis
    Sadia Beloribi‐Djefaflia, Carole Siret, Dominique Lombardo · 2014 · Oncoscience
21. Does Parkinson’s Disease and Type-2 Diabetes Mellitus Present Common Pathophysiological Mechanisms and Treatments?
    Marcelo M. S. Lima, Adriano Targa, Ana Carolina D. Noseda, Laís Soares Rodrigues, Ana Márcia Delattre, Fabiola Vila dos Santos, Mariana Fortes, Maira J. Maturana, Anete Curte Ferraz · 2014 · CNS & Neurological Disorders - Drug Targets
22. Exercise and dexamethasone oppositely modulate β-cell function and survival via independent pathways in 90% pancreatectomized rats
    Soo Bong Choi, Jin Sun Jang, Sang Mee Hong, Dong Wha Jun, Sunmin Park · 2006 · Journal of Endocrinology
23. Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture
    Domenico Accili · 2018 · Diabetes
24. Sprouty-2 Overexpression in C2C12 Cells Confers Myogenic Differentiation Properties in the Presence of FGF2
    Cristina de Álvaro, Natalia J. Martinez, José M. Rojas, Margarita Lorenzo · 2005 · Molecular Biology of the Cell
25. AMPK in the Small Intestine in Normal and Pathophysiological Conditions
    Élodie Harmel, Émilie Grenier, Ali Ben Djoudi Ouadda, Mounib Elchebly, Ehud Ziv, Jean‐François Beaulieu, Alain Théophile Sané, Schohraya Spahis, Martine Laville, Emile H. Levy · 2014 · Endocrinology
26. Promotion of immune and glycaemic functions in streptozotocin-induced diabetic rats treated with un-denatured camel milk whey proteins
    Hossam Ebaid · 2014 · Nutrition & Metabolism
27. Insulin potentiates TRPC3-mediated cation currents in normal but not in insulin-resistant mouse cardiomyocytes
    Jérémy Fauconnier, Johanna T. Lanner, A SULTAN, S ZHANG, A KATZ, Joseph D. Bruton, Håkan Westerblad · 2006 · Cardiovascular Research
28. YAP/TAZ regulates the insulin signaling via IRS1/2 in endometrial cancer.
    Chao Wang, Kangjin Jeong, Hongyuan Jiang, Wei Guo, Chao Gu, Yiling Lu, Jiyong Liang · 2016 · PubMed Central
29. Modifying Effects of IL‐6 Polymorphisms on Body Size–Associated Breast Cancer Risk
    Martha L. Slattery, Karen Curtin, Carol Sweeney, Roger K. Wolff, Richard Baumgartner, Kathy B. Baumgartner, Anna R. Giuliano, Tim Byers · 2008 · Obesity
30. Insulin Regulation of Hepatic Lipid Homeostasis
    Uehara, Kahealani, Santoleri, Dominic, Whitlock, Anna E. Garcia, Titchenell, Paul M. · 2023 · Comprehensive Physiology
31. Role of Long Non-Coding RNAs and the Molecular Mechanisms Involved in Insulin Resistance
    Vianet Argelia Tello‐Flores, Fredy Omar Beltrán‐Anaya, Marco Antonio Ramírez‐Vargas, Brenda Ely Esteban-Casales, Napoleón Navarro‐Tito, Luz del Carmen Alarcón‐Romero, Carlos Aldair Luciano-Villa, Mónica Ramı́rez, Óscar Del Moral-Hernández, Eugenia Flores‐Alfaro · 2021 · International Journal of Molecular Sciences
32. Insulin Receptor Substrate-1 Deficiency Promotes Apoptosis in the Putative Intestinal Crypt Stem Cell Region, Limits Apcmin/+ Tumors, and Regulates Sox9
    Nicole M. Ramocki, Heather R. Wilkins, Scott T. Magness, James G. Simmons, Brooks Scull, Ginny H. Lee, Kirk K. McNaughton, P. Kay Lund · 2007 · Endocrinology
33. Absence of Functional Leptin Receptor Isoforms in the POUND (Leprdb/lb) Mouse Is Associated with Muscle Atrophy and Altered Myoblast Proliferation and Differentiation
    Phonepasong Arounleut, Matthew Bowser, Sunil Kumar Upadhyay, Xingming Shi, Sadanand Fulzele, Maribeth H. Johnson, Alexis M. Stranahan, William Hill, Carlos M. Isales, Mark W. Hamrick · 2013 · PLoS ONE
34. Phosphatase and Tensin Homolog Regulation of Islet Growth and Glucose Homeostasis
    Jake A. Kushner, Laura Simpson, Lynn M. Wartschow, Shaodong Guo, Matthew M. Rankin, Ramon E. Parsons, Morris F. White · 2005 · Journal of Biological Chemistry
35. Enhanced expression of glucose transporter-1 in vascular smooth muscle cells via the Akt/tuberous sclerosis complex subunit 2 (TSC2)/mammalian target of rapamycin (mTOR)/ribosomal S6 protein kinase (S6K) pathway in experimental renal failure
    Chih‐Yuan Lin, Shih-Che Hsu, Herng-Sheng Lee, Shih‐Hua Lin, Chien‐Sung Tsai, Shih-Ming Huang, Chun-Che Shih, Yu‐Juei Hsu · 2012 · Journal of Vascular Surgery
36. Molecular mechanisms involved in obesity-associated insulin resistance: Therapeutical approach
    Sonia Fernández‐Veledo, Iria Nieto-Vázquez, Rocío Vila‐Bedmar, Lucía García‐Guerra, María Alonso-Chamorro, Margarita Lorenzo · 2009 · Archives of Physiology and Biochemistry
37. The rise and fall of insulin signaling in Alzheimer’s disease
    Belal Chami, Ariah J. Steel, Suzanne M. de la Monte, Greg Trevor Sutherland · 2016 · Metabolic Brain Disease
38. Type 2 Diabetes and Cognitive Compromise
    Efrat Kravitz, James Schmeidler, Michal Schnaider Beeri · 2013 · Endocrinology and Metabolism Clinics of North America
39. IRS posttranslational modifications in regulating insulin signaling
    Jinghua Peng, Ling He · 2017 · Journal of Molecular Endocrinology
40. Edgeworthia gardneri (Wall.) Meisn. Water Extract Ameliorates Palmitate Induced Insulin Resistance by Regulating IRS1/GSK3β/FoxO1 Signaling Pathway in Human HepG2 Hepatocytes
    Yi Zhang, Li Shan Yan, Yu‐Qiang Ding, Brian Chi Yan Cheng, Gan Luo, Jing Kong, Tong Hua Liu, Shuo Feng Zhang · 2020 · Frontiers in Pharmacology
41. Biotin, coenzyme Q10, and their combination ameliorate aluminium chloride‐induced Alzheimer's disease via attenuating neuroinflammation and improving brain insulin signaling
    Hala Attia, Shaykhah Albuhayri, Sadeem Alaraidh, Amirah Alotaibi, Hazar Ibrahim Yacoub, Raeesa A. Mohamad, Maha A. Alamin · 2020 · Journal of Biochemical and Molecular Toxicology
42. Oxidative stress and vascular disease in diabetes: Is the dichotomization of insulin signaling still valid?
    Angelo Avogaro, Saula Vigili de Kreutzenberg, Gian Paolo Fadini · 2008 · Free Radical Biology and Medicine
43. Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis
    Marianna Sadagurski, Xiaocheng Charlie Dong, Martin Grosvenor Myers, Morris F. White · 2013 · Molecular Metabolism
44. The Effect of Healthy Lifestyle Strategies on the Management of Insulin Resistance in Children and Adolescents with Obesity: A Narrative Review
    Valeria Calcaterra, Elvira Verduci, Matteo Vandoni, Virginia Rossi, Giulia Fiore, Giulia Massini, Clarissa Berardo, Alessandro Gatti, Paola Baldassarre, Alice Bianchi et al. · 2022 · Nutrients
45. Therapeutic Angiogenesis in Diabetes and Hypercholesterolemia: Influence of Oxidative Stress
    Munir Boodhwani, Frank William Sellke · 2009 · Antioxidants and Redox Signaling
46. Insulin signalling to the kidney in health and disease
    Lorna J. Hale, Richard J. Coward · 2012 · Clinical Science
47. Endothelial derived factors inhibit anoikis of head and neck cancer stem cells
    Márcia Sampaio Campos, Kathleen G. Neiva, Kristy A. Meyers, Sudha Krishnamurthy, Jacques Eduardo Nor · 2011 · Oral Oncology
48. Insulin promotes proliferation, survival, and invasion in endometrial carcinoma by activating the MEK/ERK pathway
    Yingmei Wang, Yuanxi Zhu, Lizhi Zhang, Wenyan Tian, Shaofang Hua, Jing Tai Zhao, Huiying Zhang, Fengxia Xue · 2012 · Cancer Letters
49. Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation
    Sonja M. Kessler, Stephan Laggai, Elien Van Wonterghem, Katja Gemperlein, Rolf Müller, Johannes Haybaeck, Roosmarijn E. Vandenbroucke, Manfred Ogris, Claude Libert, Alexandra K. Kiemer · 2016 · Frontiers in Physiology
50. Parasite excretory‐secretory products and their effects on metabolic syndrome
    Jenny Crowe, F. E. Lumb, Maggie Harnett, William Harnett · 2017 · Parasite Immunology
51. Uncarboxylated osteocalcin ameliorates hepatic glucose and lipid metabolism in KKAy mice via activating insulin signaling pathway
    Xiaolin Zhang, Yanan Wang, Luyao Ma, Zhong-sheng Liu, Fei Ye, Jianhong Yang · 2019 · Acta Pharmacologica Sinica
52. Micronutrients and Alzheimer's disease
    Hannes B. Staehelin · 2005 · Proceedings of The Nutrition Society
53. Structural basis of insulin fibrillation
    Liwei Wang, Catherine Hall, Emiko Uchikawa, Dailu Chen, Eunhee Choi, Xuewu Zhang, Xiao‐chen Bai · 2023 · Science Advances
54. Role of Insulin Signaling in Maintaining Energy Homeostasis
    Morali D. Sharma, Alan J. Garber, John Alan Farmer · 2008 · Endocrine Practice
55. PI3-kinase activity modulates apo B available for hepatic VLDL production inapobec-1−/−mice
    Doru V. Chirieac, Nicholas O. Davidson, Charles E. Sparks, Janet D. Sparks · 2006 · American Journal of Physiology-Gastrointestinal and Liver Physiology
56. Role of E3 ubiquitin ligases in insulin resistance
    Xi‐Ding Yang, Daxiong Xiang, Yong‐Yu Yang · 2016 · Diabetes Obesity and Metabolism
57. Research progress on intervention effect and mechanism of protocatechuic acid on nonalcoholic fatty liver disease
    Yunxiao Gao, Rongrong Tian, Haiyue Liu, Huimin Xue, Ruizhe Zhang, Suping Han, Lin Ji, Weidong Huang, Jicheng Zhan, Yilin You · 2021 · Critical Reviews in Food Science and Nutrition
58. Tissue specificity on insulin action and resistance: past to recent mechanisms
    Manuel Benito · 2010 · Acta Physiologica
59. Insulin Receptor Substrate-1 Suppresses Transforming Growth Factor-β1–Mediated Epithelial-Mesenchymal Transition
    Jian Shi, Dongmei Wang, Chunmei Wang, Ying Hu, Aihua Liu, Yonglian Zhang, Bing Sun, Jianguo Song · 2009 · Cancer Research
60. EphrinA/EphA signal facilitates insulin-like growth factor-I–induced myogenic differentiation through suppression of the Ras/extracellular signal–regulated kinase 1/2 cascade in myoblast cell lines
    Masayoshi MINAMI, Tatsuya Koyama, Yuki Wakayama, Shigetomo Fukuhara, Naoki Mochizuki · 2011 · Molecular Biology of the Cell
61. TRiC/CCT chaperonins are essential for organ growth by interacting with insulin/TOR signaling in Drosophila
    Ah-Ram Kim, Kwang‐Wook Choi · 2019 · Oncogene
62. Insulin-mediated cortical activity in the slow frequency range is diminished in obese mice and promotes physical inactivity
    Hennige, A. M., Sartorius, T., Lutz, S. Z., Tschritter, O., Preissl, H., Hopp, S., Fritsche, A., Rammensee, H.-G., Ruth, P., Häring, H.-U. · 2009 · Diabetologia
63. Insulin Receptor Isoforms and Insulin Growth Factor-like Receptors: Implications in Cell Signaling, Carcinogenesis, and Chemoresistance
    Mariam Ahmed Galal, Samhar Samer Alouch, Buthainah Saad Alsultan, Huda Dahman, Nouf Abdullah Alyabis, Sarah Alammar, Ahmad Aljada · 2023 · International Journal of Molecular Sciences
64. Association between triglyceride glucose index and total bone mineral density: a cross-sectional study from NHANES 2011–2018
    Ningsheng Tian, Daiwen Chen, Huawei Han, Jie Jin, Zhiwei Li · 2024 · Scientific Reports
65. miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway
    Zhihua Li, Qiuyun Xiong, Liang Xu, Peng Duan, Qianwen Yang, Ping Zhou, Jianhong Tu · 2017 · Oncotarget
66. Functional defects in adenylyl cyclase signaling mechanisms of insulin and relaxin in skeletal muscles of rat with streptozotocin type 1 diabetes
    Alexander Olegovich Shpakov, Ludmila A. Kuznetsova, Svetlana A. Plesneva, A. P. Kolychev, В. М. Бондарева, Oksana V. Chistyakova, Marianna N. Pertseva · 2006 · Open Life Sciences
67. Knockout mouse models of insulin signaling: Relevance past and future
    Anne E. Bunner, P. Charukeshi Chandrasekera, Neal D. Barnard · 2014 · World Journal of Diabetes
68. Accelerated diabetic neuropathy in axons without neurofilaments
    Douglas William Zochodne · 2004 · Brain
69. Aging-associated insulin resistance predisposes to hypertension and its reversal by exercise: the role of vascular vasorelaxation to insulin
    Qiuxia Li, Xiong Zheng-ying, HU Bai-ping, Zhenjun Tian, Haifeng Zhang, Wen-Yi Gou, Haichang Wang, Feng Gao, Quan‐Jiang Zhang · 2008 · Basic Research in Cardiology
70. IRS-2 Partially Compensates for the Insulin Signal Defects in IRS-1−/− Mice Mediated by miR-33
    Chen-Yi Tang, Xiao-Fei Man, Yue Guo, Hao-Neng Tang, Jun Tang, Ci-La Zhou, Shu-Wen Tan, Min Wang, Hou-De Zhou · 2017 · Molecules and Cells
71. Targeting SHP2 as a therapeutic strategy for inflammatory diseases
    Yang Liu, Xiaohe Yang, Yali Wang, Yueying Yang, Dejuan Sun, Hua Li, Lixia Chen · 2021 · European Journal of Medicinal Chemistry
72. PI3K integrates the effects of insulin and leptin on large-conductance Ca2+-activated K+ channels in neuropeptide Y neurons of the hypothalamic arcuate nucleus
    Mengjie Yang, Fang Wang, Jianghua Wang, Wen‐Ning Wu, Zhuang‐Li Hu, Cheng S. Jin, Danfang Yu, Li‐Hong Long, Hui Qun Fu, Na Xie et al. · 2009 · American Journal of Physiology-Endocrinology and Metabolism
73. All roads lead to FoxO
    Michihiro Matsumoto, Domenico Accili · 2005 · Cell Metabolism
74. The AKTion in non-canonical insulin signaling
    Zhiyong Cheng, Morris F. White · 2012 · Nature Medicine
75. PI3K/Akt/mTOR pathway involvement in regulating growth hormone secretion in a rat pituitary adenoma cell line
    Carmelina Di Pasquale, Erica Gentilin, Simona Falletta, Mariaenrica Bellio, Mattia Buratto, Ettore C. degli Uberti, Maria Chiara Zatelli · 2017 · Endocrine
76. Integrating Metabolism and Longevity Through Insulin and IGF1 Signaling
    Marianna Sadagurski, Morris F. White · 2012 · Endocrinology and Metabolism Clinics of North America
77. Anti-diabetes effect of chronic intermittent hypobaric hypoxia through improving liver insulin resistance in diabetic rats
    Yanming Tian, Yan Liu, Sheng Wang, Yi Dong, Tong Su, Huijie Ma, Yi Zhang · 2016 · Life Sciences
78. Crocin ameliorates oxidative stress and suppresses renal damage in streptozotocin induced diabetic male rats
    Ayşegül Kapucu · 2020 · Biotechnic & Histochemistry
79. Effects of treadmill exercise on brain insulin signaling and β-amyloid in intracerebroventricular streptozotocin induced-memory impairment in rats
    Eun‐Bum Kang, Joon Yong Cho · 2014 · Physical Activity and Nutrition
80. From physical inactivity to immobilization: Dissecting the role of oxidative stress in skeletal muscle insulin resistance and atrophy
    Nicolas Pierre, Zéphyra Appriou, Arlette Gratas‐Delamarche, Frederic Derbré · 2015 · Free Radical Biology and Medicine
81. Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans
    Viola, Cristina M., Frittmann, Orsolya, Jenkins, Huw T., Shafi, Talha, De Meyts, Pierre, Brzozowski, Andrzej M. · 2023 · Nature Communications
82. Effects of BMP-9 and BMP-2 on the PI3K/Akt Pathway in MC3T3-E1 Preosteoblasts
    Marc-Antoine Lauzon, Olivier Drevelle, Alex Daviau, Nathalie Faucheux · 2016 · Tissue Engineering Part A
83. GH/IGF-I/insulin system in centenarians
    Giovanni Vitale, Michelangela Barbieri, Marina Kamenetskaya, Giuseppe Paolisso · 2016 · Mechanisms of Ageing and Development
84. Novel roles for JNK1 in metabolism
    Bengt‐Frederik Belgardt, Jan Mauer, Jens C. Brüning · 2010 · Aging
85. Nutritional upregulation of p85α expression is an early molecular manifestation of insulin resistance
    Cornier, M.-A., Bessesen, D. H., Gurevich, I., Leitner, J. W., Draznin, B. · 2006 · Diabetologia
86. Metabolic Syndrome and Ionic Channels in Pancreatic Beta Cells
    Marcia Hiriart, Myrian Velasco, Carlos Larqué, Carlos Manlio Díaz‐García · 2014 · Vitamins and hormones
87. Insulin and insulin-like growth factor-1 promote mast cell survival via activation of the phosphatidylinositol-3-kinase pathway
    Eva Lessmann, Gordon Grochowy, Lars Weingarten, Torsten Giesemann, Klaus Aktories, Michael Leitges, Gerald Krystal, Michael Huber · 2006 · Experimental Hematology
88. Intracellular molecular effects of insulin resistance in patients with metabolic syndrome
    Evasio Pasini, Vincenzo Flati, Silvia Paiardi, Damiano Rizzoni, Enzo Porteri, Roberto Aquilani, Deodato Assanelli, Giovanni Corsetti, Silvia Speca, Rita Rezzani et al. · 2010 · Cardiovascular Diabetology
89. Genetics and Pharmacology of Longevity
    Jorge Iván Castillo-Quan, Kerri J. Kinghorn, Ivana Bjedov · 2015 · Advances in genetics
90. PPAR β activation restores the high glucose‐induced impairment of insulin signalling in endothelial cells
    Ana María Quintela, Rosario Jiménez, Laura Piqueras, Manuel Gómez‐Guzmán, J Haro, María José Zarzuelo-Romero, Angel L. Cogolludo, María‐Jesús Sanz, Marta Toral, Miguel Romero et al. · 2014 · British Journal of Pharmacology
91. Dissecting “PI3Kness”: The Complexity of Personalized Therapy for Ovarian Cancer
    Robert C. Bast, Gordon Brent Mills · 2012 · Cancer Discovery
92. Negative Regulators of Insulin Signaling Revealed in a Genome-Wide Functional Screen
    Shih-Min A. Huang, Michael K. Hancock, Jeffrey L. Pitman, Anthony P. Orth, Nicholas Gekakis · 2009 · PLoS ONE
93. A novel spontaneous mutation of Irs1 in mice results in hyperinsulinemia, reduced growth, low bone mass and impaired adipogenesis
    Victoria DeMambro, Masanobu Kawai, Thomas L. Clemens, Keertik S. Fulzele, Jane A Maynard, Caralina Marín de Evsikova, Kenneth R. Johnson, ERNESTO M. CANALIS, Wesley G. Beamer, Clifford james Rosen et al. · 2009 · Journal of Endocrinology
94. Metabolic Dysregulation of the Insulin–Glucose Axis and Risk of Obesity-Related Cancers in the Framingham Heart Study-Offspring Cohort (1971–2008)
    Niyati Parekh, Yong Lin, Maya K. Vadiveloo, Richard B. Hayes, Grace L. Lu‐Yao · 2013 · Cancer Epidemiology Biomarkers & Prevention
95. Cardiovascular Action of Insulin in Health and Disease: Endothelial L-Arginine Transport and Cardiac Voltage-Dependent Potassium Channels
    Sebastián Dubó, David Gallegos, Lissette Cabrera, Luis Sobrevía, Leandro Zúñiga, Marcelo González · 2016 · Frontiers in Physiology
96. Insertion of a synthetic switch into insulin provides metabolite-dependent regulation of hormone–receptor activation
    Yen‐Shan Chen, Jeremy Gleaton, Yanwu Yang, Balamurugan Dhayalan, Nelson B. Phillips, Yule Liu, Laurie Broadwater, Mark A. Jarosinski, Deepak Chatterjee, Michael C. Lawrence et al. · 2021 · Proceedings of the National Academy of Sciences
97. Ceramide mediates TNF-α-induced insulin resistance on GLUT4 gene expression in brown adipocytes
    Sonia Fernández‐Veledo, Rosario Hernández, Teresa Teruel, José A. Mas, Manuel Ros, Margarita Lorenzo · 2006 · Archives of Physiology and Biochemistry
98. miR-23a-mediated migration/invasion is rescued by its target, IRS-1, in non-small cell lung cancer cells
    Mengru Cao, Yulian Li, Hailing Lu, Qingwei Meng, Long Wang, Cai Li, Xiaoqun Dong · 2014 · Journal of Cancer Research and Clinical Oncology
99. Maternal protein restriction during early lactation induces GLUT4 translocation and mTOR/Akt activation in adipocytes of adult rats
    Érica Patrícia Garcia‐Souza, Simone Vargas da Silva, Gisele Barreto Félix, Ananda Lages Rodrigues, Marta Sampaio de Freitas, Aníbal Sanchez Moura, Christina Barja‐Fidalgo · 2008 · American Journal of Physiology-Endocrinology and Metabolism
100. Clinical pathological characteristics and prognostic analysis of diabetic women with luminal subtype breast cancer
     Yuan-ting Xiao, Sheng Zhang, Guofang Hou, Xiaobei Zhang, Xiaomeng Hao, Jin Zhang · 2013 · Tumor Biology