The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Local Nanomechanical Motion of the Cell Wall of Saccharomyces cerevisiae
Abstract
We demonstrate that the cell wall of living Saccharomyces cerevisiae (baker's yeast) exhibits local temperature-dependent nanomechanical motion at characteristic frequencies. The periodic motions in the range of 0.8 to 1.6 kHz with amplitudes of ∼3 nm were measured using the cantilever of an atomic force microscope (AFM). Exposure of the cells to a metabolic inhibitor causes the periodic motion to cease. From the strong frequency dependence on temperature, we derive an activation energy of 58 kJ/mol, which is consistent with the cell's metabolism involving molecular motors such as kinesin, dynein, and myosin. The magnitude of the forces observed (∼10 nN) suggests concerted nanomechanical activity is operative in the cell.
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Binnig, G., Quate, C. F., & Gerber, C. (1986) · Physical Review Letters · doi:10.1103/physrevlett.56.930 · Cited by 14,762
Harris, C. M., Crede, C. E., & Trent, H. M. (1962) · Physics Today · doi:10.1063/1.3058391 · Cited by 1,023
Relative Microelastic Mapping of Living Cells by Atomic Force Microscopy
A-Hassan, E., Heinz, W. F., Antonik, M. D., D’Costa, N. P., Nageswaran, S., Schoenenberger, C.-A., & Hoh, J. H. (1998) · Biophysical Journal · doi:10.1016/s0006-3495(98)77868-3 · Cited by 552
Molecular motors: structural adaptations to cellular functions
Howard, J. (1997) · Nature · doi:10.1038/39247 · Cited by 494
Nanoscale Mapping of the Elasticity of Microbial Cells by Atomic Force Microscopy
Touhami, A., Nysten, B., & Dufrêne, Y. F. (2003) · Langmuir · doi:10.1021/la034136x · Cited by 466
Surface morphology and mechanical properties of MDCK monolayers by atomic force microscopy
Hoh, J. H., & Schoenenberger, C.-A. (1994) · Journal of Cell Science · doi:10.1242/jcs.107.5.1105 · Cited by 418
Lévy, R., & Maaloum, M. (2002) · Nanotechnology · doi:10.1088/0957-4484/13/1/307 · Cited by 366
Bacterial turgor pressure can be measured by atomic force microscopy
Arnoldi, M., Fritz, M., Bäuerlein, E., Radmacher, M., Sackmann, E., & Boulbitch, A. (2000) · Physical Review E · doi:10.1103/physreve.62.1034 · Cited by 301
Single Cell Mechanotransduction and Its Modulation Analyzed by Atomic Force Microscope Indentation
Charras, G. T., & Horton, M. A. (2002) · Biophysical Journal · doi:10.1016/s0006-3495(02)75638-5 · Cited by 281
Ding, D.-Q., Chikashige, Y., Haraguchi, T., & Hiraoka, Y. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.6.701 · Cited by 278
Cited by
Nanomechanical analysis of cells from cancer patients
Cross, S. E., Jin, Y.-S., Rao, J., & Gimzewski, J. K. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.388 · Cited by 1,908
Self-citationGreen symphonies: a call for studies on acoustic communication in plants
Gagliano, M. (2013) · Behavioral Ecology · doi:10.1093/beheco/ars206 · Cited by 136
Metadata
- Authors
- Pelling, A. E., Sehati, S., Gralla, E. B., Valentine, J. S., & Gimzewski, J. K.
- Venue
- Science
- Published
- 2004-08-20
- Volume
- 305
- Issue
- 5687
- Pages
- 1147-1150
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2046467293
- Cited by
- 386
- References
- 22
- FWCI
- 14.13
- Type
- journal article
- Language
- en
- Open access
- closed
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- Pelling, A. E., Sehati, S., Gralla, E. B., Valentine, J. S., & Gimzewski, J. K. (2004). Local Nanomechanical Motion of the Cell Wall of Saccharomyces cerevisiae. Science. https://doi.org/10.1126/science.1097640
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