The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
PHYTOCHROME-INTERACTING FACTOR 1 Is a Critical bHLH Regulator of Chlorophyll Biosynthesis
Abstract
Photosynthetic organisms must achieve a delicate balance between the light energy absorbed by chlorophyll and their capacity to channel that energy into productive photochemical reactions. Release of excess absorbed energy in the cell can cause lethal photooxidative damage. We identified a basic helix-loop-helix (bHLH) transcription factor, designated PHYTOCHROME-INTERACTING FACTOR 1 (PIF1), that negatively regulates chlorophyll biosynthesis. pif1 mutant seedlings accumulate excess free protochlorophyllide when grown in the dark, with consequent lethal bleaching upon exposure to light. PIF1 interacts specifically with the photoactivated conformer of phytochromes A and B, suggesting a signaling pathway by which chlorophyll biosynthetic rates are tightly controlled during the critical initial emergence of seedlings from subterranean darkness into sunlight.
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Self-citationRapid Induction of Distinct Stress Responses after the Release of Singlet Oxygen in Arabidopsis[W]
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Self-citationDirect Targeting of Light Signals to a Promoter Element-Bound Transcription Factor
Martı́nez-Garcı́a, J. F., Huq, E., & Quail, P. H. (2000) · Science · doi:10.1126/science.288.5467.859 · Cited by 687
Self-citationFLU: A negative regulator of chlorophyll biosynthesis in Arabidopsis thaliana
Meskauskiene, R., Nater, M., Goslings, D. A. M., Kessler, F., den Camp, R. O., & Apel, K. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.221252798 · Cited by 577
Self-citationHuq, E. (2002) · The EMBO Journal · doi:10.1093/emboj/21.10.2441 · Cited by 574
Self-citationLight: an indicator of time and place
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Binding of phytochrome B to its nuclear signalling partner PIF3 is reversibly induced by light
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Cited by
Light-Regulated Plant Growth and Development
Kami, C., Lorrain, S., Hornitschek, P., & Fankhauser, C. (2010) · Current Topics in Developmental Biology · doi:10.1016/s0070-2153(10)91002-8 · Cited by 927
Tetrapyrrole Biosynthesis in Higher Plants
Tanaka, R., & Tanaka, A. (2007) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.57.032905.105448 · Cited by 818
Franklin, K. A. (2008) · New Phytologist · doi:10.1111/j.1469-8137.2008.02507.x · Cited by 801
Phytochrome Signaling Mechanisms
Li, J., Li, G., Wang, H., & Wang Deng, X. (2011) · The Arabidopsis Book · doi:10.1199/tab.0148 · Cited by 561
Toledo-Ortiz, G., Johansson, H., Lee, K. P., Bou-Torrent, J., Stewart, K., Steel, G., Rodríguez-Concepción, M., & Halliday, K. J. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004416 · Cited by 494
Metadata
- Authors
- Huq, E., Al-Sady, B., Hudson, M., Kim, C., Apel, K., & Quail, P. H.
- Venue
- Science
- Published
- 2004-09-24
- Volume
- 305
- Issue
- 5692
- Pages
- 1937-1941
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1982981899
- Cited by
- 502
- References
- 18
- FWCI
- 22.12
- Type
- journal article
- Language
- en
- Open access
- closed
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- Huq, E., Al-Sady, B., Hudson, M., Kim, C., Apel, K., & Quail, P. H. (2004). PHYTOCHROME-INTERACTING FACTOR 1 Is a Critical bHLH Regulator of Chlorophyll Biosynthesis. Science. https://doi.org/10.1126/science.1099728
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